Works by Winzeler, Elizabeth A.

Results: 74
    1

    Development of Potent and Highly Selective Epoxyketone‐Based Plasmodium Proteasome Inhibitors.

    Published in:
    Chemistry - A European Journal, 2023, v. 29, n. 20, p. 1, doi. 10.1002/chem.202203958
    By:
    • Almaliti, Jehad;
    • Fajtová, Pavla;
    • Calla, Jaeson;
    • LaMonte, Gregory M.;
    • Feng, Mudong;
    • Rocamora, Frances;
    • Ottilie, Sabine;
    • Glukhov, Evgenia;
    • Boura, Evzen;
    • Suhandynata, Raymond T.;
    • Momper, Jeremiah D.;
    • Gilson, Michael K.;
    • Winzeler, Elizabeth A.;
    • Gerwick, William H.;
    • O'Donoghue, Anthony J.
    Publication type:
    Article
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    Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites.

    Published in:
    Communications Chemistry, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42004-018-0062-7
    By:
    • Beteck, Richard M.;
    • Seldon, Ronnett;
    • Coertzen, Dina;
    • van der Watt, Mariëtte E.;
    • Reader, Janette;
    • Mackenzie, Jared S.;
    • Lamprecht, Dirk A.;
    • Abraham, Matthew;
    • Eribez, Korina;
    • Müller, Joachim;
    • Rui, Feng;
    • Zhu, Guang;
    • de Grano, Ruel Valerio;
    • Williams, Ian D.;
    • Smit, Frans J.;
    • Steyn, Adrie J. C.;
    • Winzeler, Elizabeth A.;
    • Hemphill, Andrew;
    • Birkholtz, Lyn-Marie;
    • Warner, Digby F.
    Publication type:
    Article
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    A key role for lipoic acid synthesis during Plasmodium liver stage development.

    Published in:
    Cellular Microbiology, 2013, v. 15, n. 9, p. 1585, doi. 10.1111/cmi.12137
    By:
    • Falkard, Brie;
    • Kumar, T. R. Santha;
    • Hecht, Leonie‐Sophie;
    • Matthews, Krista A.;
    • Henrich, Philipp P.;
    • Gulati, Sonia;
    • Lewis, Rebecca E.;
    • Manary, Micah J.;
    • Winzeler, Elizabeth A.;
    • Sinnis, Photini;
    • Prigge, Sean T.;
    • Heussler, Volker;
    • Deschermeier, Christina;
    • Fidock, David
    Publication type:
    Article
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    Infection of Laboratory-Colonized Anopheles darlingi Mosquitoes by Plasmodium vivax.

    Published in:
    American Journal of Tropical Medicine & Hygiene, 2014, v. 90, n. 4, p. 612, doi. 10.4269/ajtmh.13-0708
    By:
    • Moreno, Marta;
    • Tong, Carlos;
    • Guzmán, Mitchel;
    • Chuquiyauri, Raul;
    • Llanos-Cuentas, Alejandro;
    • Rodriguez, Hugo;
    • Gamboa, Dionicia;
    • Meister, Stephan;
    • Winzeler, Elizabeth A.;
    • Maguina, Paula;
    • Conn, Jan E.;
    • Vinetz, Joseph M.
    Publication type:
    Article
    11

    Plasma Lipid Metabolites, Clinical Glycemic Predictors, and Incident Type 2 Diabetes.

    Published in:
    Diabetes Care, 2025, v. 48, n. 3, p. 473, doi. 10.2337/dc24-2266
    By:
    • Begzati, Arjana;
    • Godinez-Macias, Karla P.;
    • Long, Tao;
    • Watrous, Jeramie D.;
    • Moranchel, Rafael;
    • Kantz, Edward D.;
    • Tuomilehto, Jaakko;
    • Havulinna, Aki S.;
    • Niiranen, Teemu J.;
    • Jousilahti, Pekka;
    • Salomaa, Veikko;
    • Yu, Bing;
    • Norby, Faye;
    • Rebholz, Casey M.;
    • Selvin, Elizabeth;
    • Winzeler, Elizabeth A.;
    • Cheng, Susan;
    • Alotaibi, Mona;
    • Goyal, Ravi;
    • Ideker, Trey
    Publication type:
    Article
    12

    A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.

    Published in:
    PLoS Pathogens, 2022, v. 18, n. 3, p. 1, doi. 10.1371/journal.ppat.1010409
    By:
    • Beutler, Nathan;
    • Pholcharee, Tossapol;
    • Oyen, David;
    • Flores-Garcia, Yevel;
    • MacGill, Randall S.;
    • Garcia, Elijah;
    • Calla, Jaeson;
    • Parren, Mara;
    • Yang, Linlin;
    • Volkmuth, Wayne;
    • Locke, Emily;
    • Regules, Jason A.;
    • Dutta, Sheetij;
    • Emerling, Daniel;
    • Early, Angela M.;
    • Neafsey, Daniel E.;
    • Winzeler, Elizabeth;
    • King, C. Richter;
    • Zavala, Fidel;
    • Burton, Dennis R.
    Publication type:
    Article
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    Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone.

    Published in:
    Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0397-3
    By:
    • Skinner-Adams, Tina S.;
    • Fisher, Gillian M.;
    • Riches, Andrew G.;
    • Hutt, Oliver E.;
    • Jarvis, Karen E.;
    • Wilson, Tony;
    • von Itzstein, Mark;
    • Chopra, Pradeep;
    • Antonova-Koch, Yevgeniya;
    • Meister, Stephan;
    • Winzeler, Elizabeth A.;
    • Clarke, Mary;
    • Fidock, David A.;
    • Burrows, Jeremy N.;
    • Ryan, John H.;
    • Andrews, Katherine T.
    Publication type:
    Article
    17

    A high throughput screen for next-generation leads targeting malaria parasite transmission.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05777-2
    By:
    • Delves, Michael J.;
    • Miguel-Blanco, Celia;
    • Matthews, Holly;
    • Molina, Irene;
    • Ruecker, Andrea;
    • Yahiya, Sabrina;
    • Straschil, Ursula;
    • Abraham, Matthew;
    • León, María Luisa;
    • Fischer, Oliver J.;
    • Rueda-Zubiaurre, Ainoa;
    • Brandt, Jochen R.;
    • Cortés, Álvaro;
    • Barnard, Anna;
    • Fuchter, Matthew J.;
    • Calderón, Félix;
    • Winzeler, Elizabeth A.;
    • Sinden, Robert E.;
    • Herreros, Esperanza;
    • Gamo, Francisco J.
    Publication type:
    Article
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    Perspectives: The missing pieces.

    Published in:
    Nature, 2012, v. 484, n. 7395, p. S22, doi. 10.1038/484S22a
    By:
    • Crabb, Brendan S.;
    • Beeson, James G.;
    • Amino, Rogerio;
    • Ménard, Robert;
    • Waters, Andy;
    • Winzeler, Elizabeth A.;
    • Wahlgren, Mats;
    • Fidock, David A.;
    • Nwaka, Solomon
    Publication type:
    Article
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    Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2.

    Published in:
    ChemMedChem, 2022, v. 17, n. 22, p. 1, doi. 10.1002/cmdc.202200393
    By:
    • Laleu, Benoît;
    • Rubiano, Kelly;
    • Yeo, Tomas;
    • Hallyburton, Irene;
    • Anderson, Mark;
    • Crespo‐Fernandez, Benigno;
    • Gamo, Francisco‐Javier;
    • Antonova‐Koch, Yevgeniya;
    • Orjuela‐Sanchez, Pamela;
    • Wittlin, Sergio;
    • Jana, Gouranga P.;
    • Maity, Bikash C.;
    • Chenu, Elodie;
    • Duffy, James;
    • Sjö, Peter;
    • Waterson, David;
    • Winzeler, Elizabeth;
    • Guantai, Eric;
    • Fidock, David A.;
    • Hansson, Thomas G.
    Publication type:
    Article
    27

    Front Cover: Structure–Activity and Structure–Toxicity Relationships of Peptoid‐Based Histone Deacetylase Inhibitors with Dual‐Stage Antiplasmodial Activity (ChemMedChem 9/2019).

    Published in:
    ChemMedChem, 2019, v. 14, n. 9, p. 887, doi. 10.1002/cmdc.201900235
    By:
    • Mackwitz, Marcel K. W.;
    • Hesping, Eva;
    • Antonova‐Koch, Yevgeniya;
    • Diedrich, Daniela;
    • Woldearegai, Tamirat Gebru;
    • Skinner‐Adams, Tina;
    • Clarke, Mary;
    • Schöler, Andrea;
    • Limbach, Laura;
    • Kurz, Thomas;
    • Winzeler, Elizabeth A.;
    • Held, Jana;
    • Andrews, Katherine T.;
    • Hansen, Finn K.
    Publication type:
    Article
    28

    Structure–Activity and Structure–Toxicity Relationships of Peptoid‐Based Histone Deacetylase Inhibitors with Dual‐Stage Antiplasmodial Activity.

    Published in:
    ChemMedChem, 2019, v. 14, n. 9, p. 912, doi. 10.1002/cmdc.201800808
    By:
    • Mackwitz, Marcel K. W.;
    • Hesping, Eva;
    • Antonova‐Koch, Yevgeniya;
    • Diedrich, Daniela;
    • Woldearegai, Tamirat Gebru;
    • Skinner‐Adams, Tina;
    • Clarke, Mary;
    • Schöler, Andrea;
    • Limbach, Laura;
    • Kurz, Thomas;
    • Winzeler, Elizabeth A.;
    • Held, Jana;
    • Andrews, Katherine T.;
    • Hansen, Finn K.
    Publication type:
    Article
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    The core meiotic transcriptome in budding yeasts.

    Published in:
    Nature Genetics, 2000, v. 26, n. 4, p. 415, doi. 10.1038/82539
    By:
    • Primig, Michael;
    • Williams, Roy M.;
    • Winzeler, Elizabeth A.;
    • Tevzadze, Gela G.;
    • Conway, Andrew R.;
    • Hwang, Seung Y.;
    • Davis, Ronald W.;
    • Esposito, Rochelle Easton
    Publication type:
    Article
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    Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer.

    Published in:
    Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.875647
    By:
    • Abacha, Yabalu Z.;
    • Forkuo, Arnold Donkor;
    • Gbedema, Stephen Y.;
    • Mittal, Nimisha;
    • Ottilie, Sabine;
    • Rocamora, Frances;
    • Winzeler, Elizabeth A.;
    • van Schalkwyk, Donelly A.;
    • Kelly, John M.;
    • Taylor, Martin C.;
    • Reader, Janette;
    • Birkholtz, Lyn-Marie;
    • Lisgarten, David R.;
    • Cockcroft, Jeremy K.;
    • Lisgarten, John N.;
    • Palmer, Rex A.;
    • Talbert, Rosemary C.;
    • Shnyder, Steven D.;
    • Wright, Colin W.
    Publication type:
    Article
    35

    CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs.

    Published in:
    Molecular Microbiology, 2016, v. 101, n. 3, p. 381, doi. 10.1111/mmi.13397
    By:
    • Ng, Caroline L.;
    • Siciliano, Giulia;
    • Lee, Marcus C. S.;
    • de Almeida, Mariana J.;
    • Corey, Victoria C.;
    • Bopp, Selina E.;
    • Bertuccini, Lucia;
    • Wittlin, Sergio;
    • Kasdin, Rachel G.;
    • Le Bihan, Amélie;
    • Clozel, Martine;
    • Winzeler, Elizabeth A.;
    • Alano, Pietro;
    • Fidock, David A.
    Publication type:
    Article
    36

    Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08349-0
    By:
    • LaMonte, Gregory M.;
    • Orjuela-Sanchez, Pamela;
    • Calla, Jaeson;
    • Wang, Lawrence T.;
    • Li, Shangzhong;
    • Swann, Justine;
    • Cowell, Annie N.;
    • Zou, Bing Yu;
    • Abdel-Haleem Mohamed, Alyaa M.;
    • Villa Galarce, Zaira Hellen;
    • Moreno, Marta;
    • Tong Rios, Carlos;
    • Vinetz, Joseph M.;
    • Lewis, Nathan;
    • Winzeler, Elizabeth A.
    Publication type:
    Article
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    In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model.

    Published in:
    Science Translational Medicine, 2019, v. 11, n. 521, p. 1, doi. 10.1126/scitranslmed.aav1636
    By:
    • Mandt, Rebecca E. K.;
    • Lafuente-Monasterio, Maria Jose;
    • Sakata-Kato, Tomoyo;
    • Luth, Madeline R.;
    • Segura, Delfina;
    • Pablos-Tanarro, Alba;
    • Viera, Sara;
    • Magan, Noemi;
    • Ottilie, Sabine;
    • Winzeler, Elizabeth A.;
    • Lukens, Amanda K.;
    • Gamo, Francisco Javier;
    • Wirth, Dyann F.
    Publication type:
    Article
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    Direct transfer of whole genomes from bacteria to yeast.

    Published in:
    Nature Methods, 2013, v. 10, n. 5, p. 410, doi. 10.1038/nmeth.2433
    By:
    • Karas, Bogumil J;
    • Jablanovic, Jelena;
    • Sun, Lijie;
    • Ma, Li;
    • Goldgof, Gregory M;
    • Stam, Jason;
    • Ramon, Adi;
    • Manary, Micah J;
    • Winzeler, Elizabeth A;
    • Venter, J Craig;
    • Weyman, Philip D;
    • Gibson, Daniel G;
    • Glass, John I;
    • Hutchison, Clyde A;
    • Smith, Hamilton O;
    • Suzuki, Yo
    Publication type:
    Article
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