Works matching AU Winssinger, Nicolas

Results: 103

Allosterically Regulated Phosphatase Activity from Peptide-PNA Conjugates Folded Through Hybridization.

Published in:

Angewandte Chemie, 2016, v. 128, n. 30, p. 8737, doi. 10.1002/ange.201602751

By:

Machida, Takuya;
Dutt, Som;
Winssinger, Nicolas

Publication type:

Article

Identifizierung von niedermolekularen kovalenten Bromodomäne-Bindern aus einer DNA-kodierten Bibliothek.

Published in:

Angewandte Chemie, 2015, v. 127, n. 20, p. 6155, doi. 10.1002/ange.201412276

By:

Daguer, Jean-Pierre;
Zambaldo, Claudio;
Abegg, Daniel;
Barluenga, Sofia;
Tallant, Cynthia;
Müller, Susanne;
Adibekian, Alexander;
Winssinger, Nicolas

Publication type:

Article

A LecA Ligand Identified from a Galactoside-Conjugate Array Inhibits Host Cell Invasion by Pseudomonas aeruginosa.

Published in:

Angewandte Chemie, 2014, v. 126, n. 34, p. 9031, doi. 10.1002/ange.201402831

By:

Novoa, Alexandre;
Eierhoff, Thorsten;
Topin, Jérémie;
Varrot, Annabelle;
Barluenga, Sofia;
Imberty, Anne;
Römer, Winfried;
Winssinger, Nicolas

Publication type:

Article

Reaktionen an Nucleinsäuretemplaten: mehr Methoden zur Übersetzung Oligonucleotid-basierter Informationen in neue Funktionen.

Published in:

Angewandte Chemie, 2013, v. 125, n. 27, p. 6956, doi. 10.1002/ange.201208460

By:

Gorska, Katarzyna;
Winssinger, Nicolas

Publication type:

Article

Diversity-Oriented Synthesis of Diverse Polycyclic Scaffolds Inspired by the Logic of Sesquiterpene Lactones Biosynthesis.

Published in:

Angewandte Chemie, 2012, v. 124, n. 22, p. 5487, doi. 10.1002/ange.201201157

By:

Valot, Gaëlle;
Garcia, José;
Duplan, Vincent;
Serba, Christelle;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Combining recombinase polymerase amplification and DNA‐templated reaction for SARS‐CoV‐2 sensing with dual fluorescence and lateral flow assay output.

Published in:

Biopolymers, 2022, v. 113, n. 4, p. 1, doi. 10.1002/bip.23485

By:

Farrera‐Soler, Lluc;
Gonse, Arthur;
Kim, Ki Tae;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Rapid and Scalable Synthesis of cis-Fused Guaiane-Type Sesquiterpenes.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 4, p. 644, doi. 10.1002/ejoc.201501277

By:

Serba, Christelle;
Lagoutte, Roman;
Winssinger, Nicolas

Publication type:

Article

Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 20, p. 4195, doi. 10.1002/ejoc.201300201

By:

Serba, Christelle;
Winssinger, Nicolas

Publication type:

Article

DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 41, p. 7695, doi. 10.1002/anie.200903328

By:

Gorska, Katarzyna;
Huang, Kuo-Ting;
Chaloin, Olivier;
Winssinger, Nicolas

Publication type:

Article

Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 23, p. 4432, doi. 10.1002/anie.200800233

By:

Barluenga, Sofia;
Wang, Cuihua;
Fontaine, Jean-Gonzague;
Aouadi, Kaïss;
Beebe, Kristin;
Tsutsumi, Shinji;
Neckers, Len;
Winssinger, Nicolas

Publication type:

Article

Modular Synthesis of Radicicol A and Related Resorcylic Acid Lactones, Potent Kinase Inhibitors.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 36, p. 6899, doi. 10.1002/anie.200702406

By:

Dakas, Pierre-Yves;
Barluenga, Sofia;
Totzke, Frank;
Zirrgiebel, Ute;
Winssinger, Nicolas

Publication type:

Article

Modular Asymmetric Synthesis of Aigialomycin D, a Kinase-Inhibitory ScaffoldThis project was partly supported by grants from the ARC (3683 to N.W.), the EEC (FP6-2002-Life Sciences & Health, PRO-KINASE Research Project to L.M. and MIRG-CT-2004-505317 to N.W.), and the Human Frontier Science Program (HFSP 0080/2003 to N.W.). A MENRT fellowship (P.-Y.D.) is also gratefully acknowledged. The authors thank Niels Reichardt for preliminary work on this project.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 24, p. 3951, doi. 10.1002/anie.200600593

By:

Sofia Barluenga;
Pierre-Yves Dakas;
Yoan Ferandin;
Laurent Meijer;
Nicolas Winssinger

Publication type:

Article

Modular Asymmetric Synthesis of Pochonin CA Marie Curie Fellowship to S.B. (Grant no.: HPMF-CT-2002-01968) and Fellowships from the CNRS to P.L. and E.M. are gratefully acknowledged.

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 26, p. 3467, doi. 10.1002/anie.200454108

By:

Sofia Barluenga;
Pilar Lopez;
Emilie Moulin;
Nicolas Winssinger

Publication type:

Article

Frontispiece: Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 27, p. N.PAG, doi. 10.1002/chem.201982762

By:

Angerani, Simona;
Winssinger, Nicolas

Publication type:

Article

Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 27, p. 6661, doi. 10.1002/chem.201806024

By:

Angerani, Simona;
Winssinger, Nicolas

Publication type:

Article

Turn On of a Ruthenium(II) Photocatalyst by DNA‐Templated Ligation.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 1, p. 334, doi. 10.1002/chem.201804283

By:

Anzola, Marcello;
Winssinger, Nicolas

Publication type:

Article

The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015770

By:

Grad, Iwona;
Cederroth, Christopher R.;
Walicki, Joe l;
Grey, Corinne;
Barluenga, Sofia;
Winssinger, Nicolas;
Massy, Bernard De;
Nef, Serge;
Picard, Didier

Publication type:

Article

Detection of miRNA in Live Cells by Using Templated Ru<sup>II</sup>-Catalyzed Unmasking of a Fluorophore.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 25, p. 8182, doi. 10.1002/chem.201300060

By:

Sadhu, Kalyan K.;
Winssinger, Nicolas

Publication type:

Article

Corrigendum: Expanding the Scope of PNA-Encoded Synthesis (PES): Mtt-Protected PNA Fully Orthogonal to Fmoc Chemistry and a Broad Array of Robust Diversity-Generating Reactions.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 25, p. 8022, doi. 10.1002/chem.201301579

By:

Chouikhi, Dalila;
Ciobanu, Mihai;
Zambaldo, Claudio;
Duplan, Vincent;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Expanding the Scope of PNA-Encoded Synthesis (PES): Mtt-Protected PNA Fully Orthogonal to Fmoc Chemistry and a Broad Array of Robust Diversity-Generating Reactions.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 40, p. 12698, doi. 10.1002/chem.201201337

By:

Chouikhi, Dalila;
Ciobanu, Mihai;
Zambaldo, Claudio;
Duplan, Vincent;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Asymmetric Synthesis of Pochonin E and F, Revision of Their Proposed Structure, and Their Conversion to Potent Hsp90 Inhibitors.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 29, p. 8978, doi. 10.1002/chem.201200546

By:

Karthikeyan, Ganesan;
Zambaldo, Claudio;
Barluenga, Sofia;
Zoete, Vincent;
Karplus, Martin;
Winssinger, Nicolas

Publication type:

Article

Concise Modular Asymmetric Synthesis of Deguelin, Tephrosin and Investigation into Their Mode of Action.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 32, p. 9767, doi. 10.1002/chem.201001080

By:

Garcia, José;
Barluenga, Sofia;
Beebe, Kristin;
Neckers, Len;
Winssinger, Nicolas

Publication type:

Article

Cover Picture: Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin / Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases (Chem. Eur. J. 43/2009)

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 43, p. 11409, doi. 10.1002/chem.200990168

By:

Dakas, Pierre-Yves;
Jogireddy, Rajamalleswaramma;
Valot, Gaëlle;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 43, p. 11498, doi. 10.1002/chem.200901375

By:

Jogireddy, Rajamalleswaramma;
Dakas, Pierre-Yves;
Valot, Gaëlle;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 43, p. 11490, doi. 10.1002/chem.200901373

By:

Dakas, Pierre-Yves;
Jogireddy, Rajamalleswaramma;
Valot, Gaëlle;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

DNA‐Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 9, p. 1, doi. 10.1002/anie.202215542

By:

Dockerill, Millicent;
Winssinger, Nicolas

Publication type:

Article

Cover Picture: Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization (Angew. Chem. Int. Ed. 28/2022).

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 28, p. 1, doi. 10.1002/anie.202208067

By:

Watson, Emma E.;
Russo, Francesco;
Moreau, Dimitri;
Winssinger, Nicolas

Publication type:

Article

Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 28, p. 1, doi. 10.1002/anie.202203390

By:

Watson, Emma E.;
Russo, Francesco;
Moreau, Dimitri;
Winssinger, Nicolas

Publication type:

Article

Luciferase-induced photoreductive uncaging of small-molecule effectors.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05916-9

By:

Lindberg, Eric;
Angerani, Simona;
Anzola, Marcello;
Winssinger, Nicolas

Publication type:

Article

Diversity-Oriented Synthesis of Pochonins and Biological Evaluation against a Panel of Kinases.

Published in:

Chemistry - A European Journal, 2006, v. 12, n. 34, p. 8819, doi. 10.1002/chem.200600553

By:

Moulin, Emilie;
Barluenga, Sofia;
Totzke, Frank;
Winssinger, Nicolas

Publication type:

Article

PNA Encoding (PNA=peptide nucleic acid): From Solution-Based Libraries to Organized Microarrays.

Published in:

Chemistry - A European Journal, 2005, v. 11, n. 23, p. 6792, doi. 10.1002/chem.200500305

By:

Jennifer L. Harris;
Nicolas Winssinger

Publication type:

Article

Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C.

Published in:

Chemistry - A European Journal, 2005, v. 11, n. 17, p. 4935, doi. 10.1002/chem.200500160

By:

Sofia Barluenga;
Emilie Moulin;
Pilar Lopez;
Nicolas Winssinger

Publication type:

Article

Synthesis and Biological Evaluation of Vancomycin Dimers with Potent Activity against Vancomycin-Resistant Bacteria: Target-Accelerated Combinatorial Synthesis.

Published in:

Chemistry - A European Journal, 2001, v. 7, n. 17, p. 3824, doi. 10.1002/1521-3765(20010903)7:17<3824::AID-CHEM3824>3.0.CO;2-1

By:

Nicolaou, K. C.;
Hughes, Robert;
Cho, Suk Young;
Winssinger, Nicolas;
Labischinski, Harald;
Endermann, Rainer

Publication type:

Article

Solid- and Solution-Phase Synthesis of Vancomycin and Vancomycin Analogues with Activity against Vancomycin-Resistant Bacteria.

Published in:

Chemistry - A European Journal, 2001, v. 7, n. 17, p. 3798, doi. 10.1002/1521-3765(20010903)7:17<3798::AID-CHEM3798>3.0.CO;2-6

By:

Nicolaou, K. C.;
Cho, Suk Young;
Hughes, Robert;
Winssinger, Nicolas;
Smethurst, Christian;
Labischinski, Harald;
Endermann, Rainer

Publication type:

Article

Total Synthesis of 16-Desmethylepothilone B, Epothilone B<sub>10</sub>, Epothilone F, and Related Side Chain Modified Epothilone B Analogues.

Published in:

Chemistry - A European Journal, 2000, v. 6, n. 15, p. 2783, doi. 10.1002/1521-3765(20000804)6:15<2783::AID-CHEM2783>3.0.CO;2-B

By:

Nicolaou, K. C.;
Hepworth, David;
King, N. Paul;
Finlay, M. Raymond V.;
Scarpelli, Rita;
Pereira, M. Manuela A.;
Bollbuck, Birgit;
Bigot, Antony;
Werschkun, Barbara;
Winssinger, Nicolas

Publication type:

Article

Total Synthesis of Vancomycin-Part 4: Attachment of the Sugar Moieties and Completion of the Synthesis.

Published in:

Chemistry - A European Journal, 1999, v. 5, n. 9, p. 2648, doi. 10.1002/(SICI)1521-3765(19990903)5:9<2648::AID-CHEM2648>3.0.CO;2-Q

By:

Nicolaou, K. C.;
Mitchell, Helen J.;
Jain, Nareshkumar F.;
Bando, Toshikazu;
Hughes, Robert;
Winssinger, Nicolas;
Natarajan, Swaminathan;
Koumbis, Alexandros E.

Publication type:

Article

Chemical Biology: From Small Molecules to Systems Biology and Drug Design. Edited by Stuart L. Schreiber, Tarun Kapoor, and Günther Wess.

Published in:

ChemBioChem, 2007, v. 8, n. 11, p. 1326, doi. 10.1002/cbic.200700329

By:

Winssinger, Nicolas

Publication type:

Article

Self-Assembled Small-Molecule Microarrays for Protease Screening and Profiling.

Published in:

ChemBioChem, 2006, v. 7, n. 11, p. 1790, doi. 10.1002/cbic.200600242

By:

Hugo D. Urbina;
François Debaene;
Bernard Jost;
Christine Bole-Feysot;
Daniel E. Mason;
Petr Kuzmic;
Jennifer L. Harris;
Nicolas Winssinger

Publication type:

Article

DNA‐Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution.

Published in:

Angewandte Chemie, 2023, v. 135, n. 9, p. 1, doi. 10.1002/ange.202215542

By:

Dockerill, Millicent;
Winssinger, Nicolas

Publication type:

Article

Titelbild: Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization (Angew. Chem. 28/2022).

Published in:

Angewandte Chemie, 2022, v. 134, n. 28, p. 1, doi. 10.1002/ange.202208067

By:

Watson, Emma E.;
Russo, Francesco;
Moreau, Dimitri;
Winssinger, Nicolas

Publication type:

Article

Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization.

Published in:

Angewandte Chemie, 2022, v. 134, n. 28, p. 1, doi. 10.1002/ange.202203390

By:

Watson, Emma E.;
Russo, Francesco;
Moreau, Dimitri;
Winssinger, Nicolas

Publication type:

Article

Synthesis of Protein-Oligonucleotide Conjugates.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 10, p. N.PAG, doi. 10.3390/biom12101523

By:

Watson, Emma E.;
Winssinger, Nicolas

Publication type:

Article

Kinesin-1 activity recorded in living cells with a precipitating dye.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21626-1

By:

Angerani, Simona;
Lindberg, Eric;
Klena, Nikolai;
Bleck, Christopher K. E.;
Aumeier, Charlotte;
Winssinger, Nicolas

Publication type:

Article

Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation.

Published in:

Proteomics - Clinical Applications, 2010, v. 4, n. 8/9, p. 750, doi. 10.1002/prca.201090030

By:

Broggini-Tenzer, Angela;
Hollenstein, Andreas;
Pianowski, Zbigniew;
Wampfler, Andrea;
Furmanova, Polina;
Winssinger, Nicolas;
Pruschy, Martin

Publication type:

Article

Biography of Professor Nicolaou: a journey to the extremes of molecular complexity.

Published in:

Journal of Antibiotics, 2018, v. 71, n. 2, p. 149, doi. 10.1038/ja.2017.144

By:

Winssinger, Nicolas

Publication type:

Article

Synthesis of deoxyelephantopin analogues.

Published in:

Journal of Antibiotics, 2018, v. 71, n. 2, p. 248, doi. 10.1038/ja.2017.132

By:

Lagoutte, Roman;
Serba, Christelle;
Winssinger, Nicolas

Publication type:

Article

DNA as a Platform to Program Assemblies with Emerging Functions in Chemical Biology.

Published in:

Israel Journal of Chemistry, 2013, v. 53, n. 1/2, p. 75, doi. 10.1002/ijch.201200100

By:

Sadhu, Kalyan K.;
Röthlingshöfer, Manuel;
Winssinger, Nicolas

Publication type:

Article

Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56746-5

By:

von Glasenapp, Victoria;
C. Almeida, Ana;
Chang, Dalu;
Gasic, Ivana;
Winssinger, Nicolas;
Gotta, Monica

Publication type:

Article

Control of Therapeutic Activity through Programmed Assembly.

Published in:

Chimia, 2025, v. 79, n. 3, p. 128, doi. 10.2533/chimia.2025.128

By:

Dockerill, Millicent;
Winssinger, Nicolas

Publication type:

Article

Conference Report.

Published in:

Chimia, 2022, v. 76, n. 6, p. 604, doi. 10.2533/chimia.2022.604

By:

Hoogendoorn, Sascha;
Winssinger, Nicolas;
Matile, Stefan

Publication type:

Article