Works by Willis, Christine L.

Results: 60

Resistance to and synthesis of the antibiotic mupirocin.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 4, p. 281, doi. 10.1038/nrmicro2278

By:

Thomas, Christopher M.;
Hothersall, Joanne;
Willis, Christine L.;
Simpson, Thomas J.

Publication type:

Article

Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases.

Published in:

ChemBioChem, 2023, v. 24, n. 14, p. 1, doi. 10.1002/cbic.202300382

By:

Zorn, Katja;
Back, Catherine R.;
Barringer, Rob;
Chadimová, Veronika;
Manzo‐Ruiz, Monserrat;
Mbatha, Sbusisiwe Z.;
Mobarec, Juan‐Carlos;
Williams, Sam E.;
van der Kamp, Marc W.;
Race, Paul R.;
Willis, Christine L.;
Hayes, Martin A.

Publication type:

Article

Core Steps to the Azaphilone Family of Fungal Natural Products.

Published in:

ChemBioChem, 2021, v. 22, n. 21, p. 3027, doi. 10.1002/cbic.202100240

By:

Williams, Katherine;
Greco, Claudio;
Bailey, Andrew M.;
Willis, Christine L.

Publication type:

Article

Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans‐AT Polyketide Synthase Pathway.

Published in:

ChemBioChem, 2018, v. 19, n. 8, p. 836, doi. 10.1002/cbic.201800036

By:

Mohammad, Hadi H.;
Connolly, Jack A.;
Song, Zhongshu;
Hothersall, Joanne;
Race, Paul R.;
Willis, Christine L.;
Simpson, Thomas J.;
Winn, Peter J.;
Thomas, Christopher M.

Publication type:

Article

Bicyclic Oxygen Heterocycles from γ,δ-Unsaturated Alcohols: Synthetic Targets Inspired by Blepharocalyxin D.

Published in:

Angewandte Chemie, 2012, v. 124, n. 16, p. 3967, doi. 10.1002/ange.201108315

By:

Bunt, Adam J.;
Bailey, Christopher D.;
Cons, Benjamin D.;
Edwards, Sophie J.;
Elsworth, Jon D.;
Pheko, Tshepo;
Willis, Christine L.

Publication type:

Article

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390.

Published in:

Angewandte Chemie, 2011, v. 123, n. 14, p. 3329, doi. 10.1002/ange.201007029

By:

Murphy, Annabel C.;
Fukuda, Daisuke;
Song, Zhongshu;
Hothersall, Joanne;
Cox, Russell J.;
Willis, Christine L.;
Thomas, Christopher M.;
Simpson, Thomas J.

Publication type:

Article

Synthesis and Incorporation of the First Polyketide Synthase Free Intermediate in Monocerin Biosynthesis ( We thank the Engineering and Physical Sciences Research Council for support (GR/N21352) and for a research studentship (L.C.A.), and Dr. M. P. Crump for a 600 MHz NMR spectrum. )

Published in:

Angewandte Chemie, 2004, v. 116, n. 6, p. 745, doi. 10.1002/ange.200352652

By:

Lorraine C. Axford;
Thomas J. Simpson;
Christine L. Willis

Publication type:

Article

Synthesis of [6-13C]-L-lysine.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 1996, v. 38, n. 1, p. 95, doi. 10.1002/(SICI)1099-1344(199601)38:1<95::AID-JLCR816>3.0.CO;2-Q

By:

Sutherland, Andrew;
Willis, Christine L.

Publication type:

Article

Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 3, p. 1017, doi. 10.1007/s00253-011-3145-2

By:

Hothersall, Joanne;
Murphy, Annabel C.;
Iqbal, Zafar;
Campbell, Genevieve;
Stephens, Elton R.;
Ji'en Wu;
Cooper, Helen;
Atkinson, Steve;
Williams, Paul;
Crosby, John;
Willis, Christine L.;
Cox, Russell J.;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

Structure and Function of the α‐Hydroxylation Bimodule of the Mupirocin Polyketide Synthase.

Published in:

Angewandte Chemie, 2023, v. 135, n. 47, p. 1, doi. 10.1002/ange.202312514

By:

Winter, Ashley J.;
Khanizeman, R. Nisha;
Barker‐Mountford, Abigail M. C.;
Devine, Andrew J.;
Wang, Luoyi;
Song, Zhongshu;
Davies, Jonathan A.;
Race, Paul R.;
Williams, Christopher;
Simpson, Thomas J.;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis.

Published in:

Angewandte Chemie, 2023, v. 135, n. 3, p. 1, doi. 10.1002/ange.202213053

By:

Devine, Andrew J.;
Parnell, Alice E.;
Back, Catherine R.;
Lees, Nicholas R.;
Johns, Samuel T.;
Zulkepli, Ainul Z.;
Barringer, Rob;
Zorn, Katja;
Stach, James E. M.;
Crump, Matthew P.;
Hayes, Martin A.;
van der Kamp, Marc W.;
Race, Paul R.;
Willis, Christine L.

Publication type:

Article

Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin.

Published in:

Angewandte Chemie, 2022, v. 134, n. 50, p. 1, doi. 10.1002/ange.202212393

By:

Winter, Ashley J.;
Rowe, Matthew T.;
Weir, Angus N. M.;
Akter, Nahida;
Mbatha, Sbusisiwe Z.;
Walker, Paul D.;
Williams, Christopher;
Song, Zhongshu;
Race, Paul R.;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl‐Acyl Carrier Protein Binding Site of FabI.

Published in:

Angewandte Chemie, 2020, v. 132, n. 26, p. 10636, doi. 10.1002/ange.201915407

By:

Fage, Christopher D.;
Lathouwers, Thomas;
Vanmeert, Michiel;
Gao, Ling‐Jie;
Vrancken, Kristof;
Lammens, Eveline‐Marie;
Weir, Angus N. M.;
Degroote, Ruben;
Cuppens, Harry;
Kosol, Simone;
Simpson, Thomas J.;
Crump, Matthew P.;
Willis, Christine L.;
Herdewijn, Piet;
Lescrinier, Eveline;
Lavigne, Rob;
Anné, Jozef;
Masschelein, Joleen

Publication type:

Article

Control of β‐Branching in Kalimantacin Biosynthesis: Application of 13C NMR to Polyketide Programming.

Published in:

Angewandte Chemie, 2019, v. 131, n. 36, p. 12576, doi. 10.1002/ange.201905482

By:

Walker, Paul D.;
Williams, Christopher;
Weir, Angus N. M.;
Wang, Luoyi;
Crosby, John;
Race, Paul R.;
Simpson, Thomas J.;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

Sequential Photochemical and Prins Reactions for the Diastereoselective Synthesis of Tricyclic Scaffolds.

Published in:

Angewandte Chemie, 2019, v. 131, n. 27, p. 9193, doi. 10.1002/ange.201903488

By:

Donnelly, Bethan L.;
Elliott, Luke D.;
Willis, Christine L.;
Booker‐Milburn, Kevin I.

Publication type:

Article

An Esterase‐like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis.

Published in:

Angewandte Chemie, 2019, v. 131, n. 8, p. 2327, doi. 10.1002/ange.201812105

By:

Lees, Nicholas R.;
Han, Li‐Chen;
Byrne, Matthew J.;
Davies, Jonathan A.;
Parnell, Alice E.;
Moreland, Pollyanna E. J.;
Stach, James E. M.;
van der Kamp, Marc W.;
Willis, Christine L.;
Race, Paul R.

Publication type:

Article

Synthesis of isotopically labelled amino acids.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2007, v. 50, n. 5/6, p. 399, doi. 10.1002/jlcr.1301

By:

Rees, David O.;
Bushby, Nick;
Harding, John R.;
Song, Chuanjun;
Willis, Christine L.

Publication type:

Article

Methods for the synthesis of carbon-13 labelled acids and esters.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2007, v. 50, n. 5/6, p. 338, doi. 10.1002/jlcr.1198

By:

Jordan, Angela C.;
Axford, Lorraine C.;
Harding, John R.;
O'Connell, Yvonne;
Simpson, Thomas J.;
Willis, Christine L.

Publication type:

Article

The Bristol Sponge Microbiome Collection: A Unique Repository of Deep-Sea Microorganisms and Associated Natural Products.

Published in:

Antibiotics (2079-6382), 2020, v. 9, n. 8, p. 509, doi. 10.3390/antibiotics9080509

By:

Williams, Sam E.;
Stennett, Henry L.;
Back, Catherine R.;
Tiwari, Kavita;
Ojeda Gomez, Jorge;
Challand, Martin R.;
Hendry, Katharine R.;
Spencer, James;
Essex-Lopresti, Angela E.;
Willis, Christine L.;
Curnow, Paul;
Race, Paul R.

Publication type:

Article

In silico analyses of maleidride biosynthetic gene clusters.

Published in:

Fungal Biology & Biotechnology, 2022, v. 9, n. 1, p. 1, doi. 10.1186/s40694-022-00132-z

By:

Williams, Katherine;
de Mattos-Shipley, Kate M. J.;
Willis, Christine L.;
Bailey, Andrew M.

Publication type:

Article

Diastereodivergent Synthesis of Trisubstituted Alkenes through Protodeboronation of Allylic Boronic Esters: Application to the Synthesis of the Californian Red Scale Beetle Pheromone.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 50, p. 12444, doi. 10.1002/anie.201207312

By:

Hesse, Matthew J.;
Butts, Craig P.;
Willis, Christine L.;
Aggarwal, Varinder K.

Publication type:

Article

Bicyclic Oxygen Heterocycles from γ,δ-Unsaturated Alcohols: Synthetic Targets Inspired by Blepharocalyxin D.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 16, p. 3901, doi. 10.1002/anie.201108315

By:

Bunt, Adam J.;
Bailey, Christopher D.;
Cons, Benjamin D.;
Edwards, Sophie J.;
Elsworth, Jon D.;
Pheko, Tshepo;
Willis, Christine L.

Publication type:

Article

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 14, p. 3271, doi. 10.1002/anie.201007029

By:

Murphy, Annabel C.;
Fukuda, Daisuke;
Song, Zhongshu;
Hothersall, Joanne;
Cox, Russell J.;
Willis, Christine L.;
Thomas, Christopher M.;
Simpson, Thomas J.

Publication type:

Article

Genetic regulation of gibberellin deactivation in Pisum.

Published in:

Plant Journal, 1995, v. 7, n. 3, p. 513, doi. 10.1046/j.1365-313X.1995.7030513.x

By:

Ross, John J.;
Reid, James B.;
Swain, Stephen M.;
Hasan, Omar;
Poole, Andrew T.;
Hedden, Peter;
Willis, Christine L.

Publication type:

Article

Structure and Function of the α‐Hydroxylation Bimodule of the Mupirocin Polyketide Synthase.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 47, p. 1, doi. 10.1002/anie.202312514

By:

Winter, Ashley J.;
Khanizeman, R. Nisha;
Barker‐Mountford, Abigail M. C.;
Devine, Andrew J.;
Wang, Luoyi;
Song, Zhongshu;
Davies, Jonathan A.;
Race, Paul R.;
Williams, Christopher;
Simpson, Thomas J.;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 3, p. 1, doi. 10.1002/anie.202213053

By:

Devine, Andrew J.;
Parnell, Alice E.;
Back, Catherine R.;
Lees, Nicholas R.;
Johns, Samuel T.;
Zulkepli, Ainul Z.;
Barringer, Rob;
Zorn, Katja;
Stach, James E. M.;
Crump, Matthew P.;
Hayes, Martin A.;
van der Kamp, Marc W.;
Race, Paul R.;
Willis, Christine L.

Publication type:

Article

Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 50, p. 1, doi. 10.1002/anie.202212393

By:

Winter, Ashley J.;
Rowe, Matthew T.;
Weir, Angus N. M.;
Akter, Nahida;
Mbatha, Sbusisiwe Z.;
Walker, Paul D.;
Williams, Christopher;
Song, Zhongshu;
Race, Paul R.;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl‐Acyl Carrier Protein Binding Site of FabI.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 26, p. 10549, doi. 10.1002/anie.201915407

By:

Fage, Christopher D.;
Lathouwers, Thomas;
Vanmeert, Michiel;
Gao, Ling‐Jie;
Vrancken, Kristof;
Lammens, Eveline‐Marie;
Weir, Angus N. M.;
Degroote, Ruben;
Cuppens, Harry;
Kosol, Simone;
Simpson, Thomas J.;
Crump, Matthew P.;
Willis, Christine L.;
Herdewijn, Piet;
Lescrinier, Eveline;
Lavigne, Rob;
Anné, Jozef;
Masschelein, Joleen

Publication type:

Article

Control of β‐Branching in Kalimantacin Biosynthesis: Application of 13C NMR to Polyketide Programming.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 36, p. 12446, doi. 10.1002/anie.201905482

By:

Walker, Paul D.;
Williams, Christopher;
Weir, Angus N. M.;
Wang, Luoyi;
Crosby, John;
Race, Paul R.;
Simpson, Thomas J.;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

Sequential Photochemical and Prins Reactions for the Diastereoselective Synthesis of Tricyclic Scaffolds.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 27, p. 9095, doi. 10.1002/anie.201903488

By:

Donnelly, Bethan L.;
Elliott, Luke D.;
Willis, Christine L.;
Booker‐Milburn, Kevin I.

Publication type:

Article

Sequential Photochemical and Prins Reactions for the Diastereoselective Synthesis of Tricyclic Scaffolds.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 27, p. 9095, doi. 10.1002/anie.201903488

By:

Donnelly, Bethan L.;
Elliott, Luke D.;
Willis, Christine L.;
Booker‐Milburn, Kevin I.

Publication type:

Article

An Esterase‐like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 8, p. 2305, doi. 10.1002/anie.201812105

By:

Lees, Nicholas R.;
Han, Li‐Chen;
Byrne, Matthew J.;
Davies, Jonathan A.;
Parnell, Alice E.;
Moreland, Pollyanna E. J.;
Stach, James E. M.;
van der Kamp, Marc W.;
Willis, Christine L.;
Race, Paul R.

Publication type:

Article

Divergent Tandem Acyl Carrier Proteins Necessitate In‐Series Polyketide Processing in the Leinamycin Family.

Published in:

Angewandte Chemie, 2025, v. 137, n. 2, p. 1, doi. 10.1002/ange.202414165

By:

Phillips, Annabel P.;
Winter, Ashley J.;
Hooper, Chloe M.;
Williams, Christopher;
Crosby, John;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

An Integrated Module Performs Selective 'Online' Epoxidation in the Biosynthesis of the Antibiotic Mupirocin.

Published in:

Angewandte Chemie, 2024, v. 136, n. 49, p. 1, doi. 10.1002/ange.202410502

By:

Winter, Ashley J.;
de Courcy‐Ireland, Felix;
Phillips, Annabel P.;
Barker, Joseph M.;
Bakar, Nurfarhanim A.;
Akter, Nahida;
Wang, Luoyi;
Song, Zhongshu;
Crosby, John;
Williams, Christopher;
Willis, Christine L.;
Crump, Matthew P.

Publication type:

Article

In vivo Mutational Analysis of the Mupirocin Gene Cluster Reveals Labile Points in the Biosynthetic Pathway: the 'Leaky Hosepipe' Mechanism.

Published in:

ChemBioChem, 2008, v. 9, n. 9, p. 1500, doi. 10.1002/cbic.200800085

By:

Wu, Ji'en;
Hothersall, Joanne;
Mazzetti, Carlo;
O'Connell, Yvonne;
Shields, Jennifer A.;
Rahman, Ayesha S.;
Cox, Russell J.;
Crosby, John;
Simpson, Thomas J.;
Thomas, Christopher M.;
Willis, Christine L.

Publication type:

Article

Synthesis of [1,2-13C2,15N]-L-Homoserine and Its Incorporation by the PKS-NRPS System of Fusarium moniliforme into the Mycotoxin Fusarin C.

Published in:

ChemBioChem, 2007, v. 8, n. 1, p. 46, doi. 10.1002/cbic.200600404

By:

David O. Rees;
Nick Bushby;
Russell J. Cox;
John R. Harding;
Thomas J. Simpson;
Christine L. Willis

Publication type:

Article

Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-38038-9

By:

Connolly, Jack A.;
Wilson, Amber;
Macioszek, Malgorzata;
Song, Zhongshu;
Wang, Luoyi;
Mohammad, Hadi H.;
Yadav, Mukul;
di Martino, Maura;
Miller, Claire E.;
Hothersall, Joanne;
Haines, Anthony S.;
Stephens, Elton R.;
Crump, Matthew P.;
Willis, Christine L.;
Simpson, Thomas J.;
Winn, Peter J.;
Thomas, Christopher M.

Publication type:

Article

Synthesis and Incorporation of the First Polyketide Synthase Free Intermediate in Monocerin Biosynthesis ( We thank the Engineering and Physical Sciences Research Council for support (GR/N21352) and for a research studentship (L.C.A.), and Dr. M. P. Crump for a 600 MHz NMR spectrum. )

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 6, p. 727, doi. 10.1002/anie.200352652

By:

Lorraine C. Axford;
Thomas J. Simpson;
Christine L. Willis

Publication type:

Article

Rücktitelbild: Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics (Angew. Chem. 14/2017).

Published in:

Angewandte Chemie, 2017, v. 129, n. 14, p. 4126, doi. 10.1002/ange.201702123

By:

Gao, Shu ‐ Shan;
Wang, Luoyi;
Song, Zhongshu;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Cox, Russell J.;
Crump, Matthew P.;
Race, Paul R.;
Thomas, Christopher M.;
Simpson, Thomas J.;
Willis, Christine L.

Publication type:

Article

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Published in:

Angewandte Chemie, 2017, v. 129, n. 14, p. 3988, doi. 10.1002/ange.201611590

By:

Gao, Shu ‐ Shan;
Wang, Luoyi;
Song, Zhongshu;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Cox, Russell J.;
Crump, Matthew P.;
Race, Paul R.;
Thomas, Christopher M.;
Simpson, Thomas J.;
Willis, Christine L.

Publication type:

Article

Heterologe Produktion pilzlicher Maleidride enthüllt die kryptische Cyclisierung in ihrer Biosynthese.

Published in:

Angewandte Chemie, 2016, v. 128, n. 23, p. 6896, doi. 10.1002/ange.201511882

By:

Williams, Katherine;
Szwalbe, Agnieszka J.;
Mulholland, Nicholas P.;
Vincent, Jason L.;
Bailey, Andrew M.;
Willis, Christine L.;
Simpson, Thomas J.;
Cox, Russell J.

Publication type:

Article

Highly Selective Allylborations of Aldehydes Using α,α-Disubstituted Allylic Pinacol Boronic Esters.

Published in:

Angewandte Chemie, 2014, v. 126, n. 24, p. 6259, doi. 10.1002/ange.201402995

By:

Hesse, Matthew J.;
Essafi, Stéphanie;
Watson, Charlotte G.;
Harvey, Jeremy N.;
Hirst, David;
Willis, Christine L.;
Aggarwal, Varinder K.

Publication type:

Article

Diastereodivergent Synthesis of Trisubstituted Alkenes through Protodeboronation of Allylic Boronic Esters: Application to the Synthesis of the Californian Red Scale Beetle Pheromone.

Published in:

Angewandte Chemie, 2012, v. 124, n. 50, p. 12612, doi. 10.1002/ange.201207312

By:

Hesse, Matthew J.;
Butts, Craig P.;
Willis, Christine L.;
Aggarwal, Varinder K.

Publication type:

Article

Correction to: ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.

Published in:

2020

By:

Evans, Charles E.;
Miners, James S.;
Piva, Giulia;
Willis, Christine L.;
Heard, David M.;
Kidd, Emma J.;
Good, Mark A.;
Kehoe, Patrick G.

Publication type:

Correction Notice

ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 3, p. 485, doi. 10.1007/s00401-019-02098-6

By:

Evans, Charles E.;
Miners, James S.;
Piva, Giulia;
Willis, Christine L.;
Heard, David M.;
Kidd, Emma J.;
Good, Mark A.;
Kehoe, Patrick G.

Publication type:

Article

Strobilurin biosynthesis in Basidiomycete fungi.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06202-4

By:

Nofiani, Risa;
de Mattos-Shipley, Kate;
Lebe, Karen E.;
Han, Li-Chen;
Iqbal, Zafar;
Bailey, Andrew M.;
Willis, Christine L.;
Simpson, Thomas J.;
Cox, Russell J.

Publication type:

Article

Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01659-1

By:

Alberti, Fabrizio;
Khairudin, Khairunisa;
Rodriguez Venegas, Edith;
Davies, Jonathan A.;
Hayes, Patrick M.;
Willis, Christine L.;
Bailey, Andy M.;
Foster, Gary D.

Publication type:

Article

Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide β-methyl branch incorporation.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71850-w

By:

Nair, Asha V.;
Robson, Alice;
Ackrill, Thomas D.;
Till, Marisa;
Byrne, Matthew J.;
Back, Catherine R.;
Tiwari, Kavita;
Davies, Jonathan A.;
Willis, Christine L.;
Race, Paul R.

Publication type:

Article

A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018031

By:

Fukuda, Daisuke;
Haines, Anthony S.;
Song, Zhongshu;
Murphy, Annabel C.;
Hothersall, Joanne;
Stephens, Elton R.;
Gurney, Rachel;
Cox, Russell J.;
Crosby, John;
Willis, Christine L.;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

A Natural Diels‐Alder Biocatalyst Enables Efficient [4+2] Cycloaddition Under Harsh Reaction Conditions.

Published in:

ChemCatChem, 2019, v. 11, n. 20, p. 5027, doi. 10.1002/cctc.201901285

By:

Marsh, Carl O.;
Lees, Nicholas R.;
Han, Li‐Chen;
Byrne, Matthew J.;
Mbatha, Sbusisiwe Z.;
Maschio, Laurence;
Pagden‐Ratcliffe, Sebastian;
Duke, Phillip W.;
Stach, James E. M.;
Curnow, Paul;
Willis, Christine L.;
Race, Paul R.

Publication type:

Article