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Therapeutically targeting the unique disease landscape of pediatric high-grade gliomas.
- Published in:
- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1347694
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- Publication type:
- Article
Integrin-linked kinase expression in myeloid cells promotes colon tumorigenesis.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1270194
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- Publication type:
- Article
The protein kinase R modifies gut physiology to limit colitis.
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- Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1106737
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- Publication type:
- Article
Integrin-Linked Kinase Expression Characterizes the Immunosuppressive Tumor Microenvironment in Colorectal Cancer and Regulates PD-L1 Expression and Immune Cell Cytotoxicity.
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- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.836005
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- Publication type:
- Article
A Potential Role for Integrin-Linked Kinase in Colorectal Cancer Growth and Progression via Regulating Senescence and Immunity.
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- Frontiers in Genetics, 2021, v. 11, p. 1, doi. 10.3389/fgene.2021.638558
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- Publication type:
- Article
(−)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 1, p. 58, doi. 10.1111/1440-1681.12854
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- Article
Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry.
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- 2017
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- Publication type:
- journal article
An Emergence Framework of Carcinogenesis.
- Published in:
- Frontiers in Oncology, 2017, p. 1, doi. 10.3389/fonc.2017.00198
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- Publication type:
- Article
Auto-phosphorylation Represses Protein Kinase R Activity.
- Published in:
- Scientific Reports, 2017, p. 44340, doi. 10.1038/srep44340
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- Article
Activation of cGAS-dependent antiviral responses by DNA intercalating agents.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 1, p. 198, doi. 10.1093/nar/gkw878
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- Article
Cre-dependent DNA recombination activates a STING-dependent innate immune response.
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- Nucleic Acids Research, 2016, v. 44, n. 11, p. 5356, doi. 10.1093/nar/gkw405
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- Article
The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.
- Published in:
- FEBS Journal, 2015, v. 282, n. 24, p. 4766, doi. 10.1111/febs.13533
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- Article
Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and Diversity.
- Published in:
- Biomolecules (2218-273X), 2015, v. 5, n. 4, p. 3087, doi. 10.3390/biom5043087
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- Publication type:
- Article
The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.
- Published in:
- Nature Communications, 2015, v. 6, n. 4, p. 6795, doi. 10.1038/ncomms7795
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- Publication type:
- Article
Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1177, doi. 10.1093/nar/gku1343
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- Publication type:
- Article
Molecular dynamics reveal a novel kinase–substrate interface that regulates protein translation.
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- Journal of Molecular Cell Biology, 2014, v. 6, n. 6, p. 473, doi. 10.1093/jmcb/mju044
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- Publication type:
- Article
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
- Published in:
- Nature Immunology, 2014, v. 15, n. 2, p. 152, doi. 10.1038/ni.2784
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- Publication type:
- Article
Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.
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- Nucleic Acids Research, 2013, v. 41, n. 5, p. 3436, doi. 10.1093/nar/gks1477
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- Publication type:
- Article
A miR-19 regulon that controls NF-κB signaling.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 16, p. 8048, doi. 10.1093/nar/gks521
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- Publication type:
- Article
Making Sense of Viral RNA Sensing.
- Published in:
- 2011
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- Publication type:
- Opinion
Analysis of microRNA turnover in mammalian cells following Dicer1 ablation.
- Published in:
- Nucleic Acids Research, 2011, v. 39, n. 13, p. 5692, doi. 10.1093/nar/gkr148
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- Publication type:
- Article
Different modes of interaction by TIAR and HuR with target RNA and DNA.
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- Nucleic Acids Research, 2011, v. 39, n. 3, p. 1117, doi. 10.1093/nar/gkq837
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- Publication type:
- Article
Role of PKR and Type I IFNs in Viral Control during Primary and Secondary Infection.
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- PLoS Pathogens, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.ppat.1000966
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- Publication type:
- Article
Viral apoptosis is induced by IRF-3-mediated activation of Bax.
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- EMBO Journal, 2010, v. 29, n. 10, p. 1762, doi. 10.1038/emboj.2010.50
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- Publication type:
- Article
ATF3 transcription factor and its emerging roles in immunity and cancer.
- Published in:
- Journal of Molecular Medicine, 2009, v. 87, n. 11, p. 1053, doi. 10.1007/s00109-009-0520-x
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- Publication type:
- Article
siRNA delivery not Toll-free.
- Published in:
- Nature Biotechnology, 2009, v. 27, n. 10, p. 911, doi. 10.1038/nbt1009-911
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- Publication type:
- Article
An Antiviral Response Directed by PKR Phosphorylation of the RNA Helicase A.
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- PLoS Pathogens, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.ppat.1000311
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- Publication type:
- Article
Interferon-inducible antiviral effectors.
- Published in:
- 2008
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- Publication type:
- journal article
Human Immunodeficiency Virus-1/Surface Glycoprotein 120 Induces Apoptosis through RNA-Activated Protein Kinase Signaling in Neurons.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 41, p. 11047, doi. 10.1523/JNEUROSCI.2733-07.2007
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- Publication type:
- Article
Fine-tuning of the innate immune response by microRNAs.
- Published in:
- Immunology & Cell Biology, 2007, v. 85, n. 6, p. 458, doi. 10.1038/sj.icb.7100091
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- Publication type:
- Article
Type I Interferon Inhibits Antibody Responses Induced by a Chimpanzee Adenovirus Vector.
- Published in:
- Molecular Therapy, 2007, v. 15, n. 2, p. 393, doi. 10.1038/sj.mt.6300024
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- Publication type:
- Article
The lack of RNA-dependent protein kinase enhances susceptibility of mice to genital herpes simplex virus type 2 infection.
- Published in:
- Immunology, 2006, v. 118, n. 4, p. 520, doi. 10.1111/j.1365-2567.2006.02403.x
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- Publication type:
- Article
A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.
- Published in:
- Nature Biotechnology, 2006, v. 24, n. 5, p. 559, doi. 10.1038/nbt1205
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- Publication type:
- Article
Stability of CXCL-8 and Related AU-Rich mRNAs in the Context of Hepatitis C Virus Replication In Vitro.
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- Journal of Infectious Diseases, 2006, v. 193, n. 6, p. 802, doi. 10.1086/500510
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- Publication type:
- Article
ARED 3.0: the large and diverse AU-rich transcriptome.
- Published in:
- Nucleic Acids Research, 2006, v. 34, n. suppl 1, p. d111, doi. 10.1093/nar/gkj052
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- Publication type:
- Article
Activation of the mammalian immune system by siRNAs.
- Published in:
- Nature Biotechnology, 2005, v. 23, n. 11, p. 1399, doi. 10.1038/nbt1161
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- Publication type:
- Article
Detection of foreign RNA: Implications for RNAi.
- Published in:
- Immunology & Cell Biology, 2005, v. 83, n. 3, p. 224, doi. 10.1111/j.1440-1711.2005.01337.x
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- Publication type:
- Article
Double-stranded RNA-dependent protein kinase (PKR) is downregulated by phorbol ester.
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- FEBS Journal, 2005, v. 272, n. 7, p. 1568, doi. 10.1111/j.1742-4658.2005.04572.x
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- Publication type:
- Article
Dicing with siRNA.
- Published in:
- Nature Biotechnology, 2005, v. 23, n. 2, p. 181, doi. 10.1038/nbt0205-181
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- Article
Transcript profiling of Wilms tumors reveals connections to kidney morphogenesis and expression patterns associated with anaplasia.
- Published in:
- Oncogene, 2005, v. 24, n. 3, p. 457, doi. 10.1038/sj.onc.1208228
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- Publication type:
- Article
Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.
- Published in:
- Oncogene, 2004, v. 23, n. 25, p. 4477, doi. 10.1038/sj.onc.1207575
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- Publication type:
- Article
Activation of the interferon system by short-interfering RNAs.
- Published in:
- Nature Cell Biology, 2003, v. 5, n. 9, p. 834, doi. 10.1038/ncb1038
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- Publication type:
- Article
ARED 2.0: an update of AU-rich element mRNA database.
- Published in:
- Nucleic Acids Research, 2003, v. 31, n. 1, p. 421, doi. 10.1093/nar/gkg023
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- Publication type:
- Article
TLR4, but not TLR2, mediates IFN-B-induced STAT1a/B-dependent gene expression in macrophages.
- Published in:
- Nature Immunology, 2002, v. 3, n. 4, p. 392, doi. 10.1038/ni774
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- Publication type:
- Article
Expression and localization of HGF and met in Wilms' tumours.
- Published in:
- Journal of Pathology, 2002, v. 196, n. 1, p. 76, doi. 10.1002/path.997
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- Publication type:
- Article
Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.
- Published in:
- EMBO Journal, 2001, v. 20, n. 10, p. 2487, doi. 10.1093/emboj/20.10.2487
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- Publication type:
- Article
ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins.
- Published in:
- Nucleic Acids Research, 2001, v. 29, n. 1, p. 246, doi. 10.1093/nar/29.1.246
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- Publication type:
- Article
A dynamically tuned double‐stranded RNA binding mechanism for the activation of antiviral kinase PKR.
- Published in:
- EMBO Journal, 2000, v. 19, n. 20, p. 5567, doi. 10.1093/emboj/19.20.5567
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- Publication type:
- Article
A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.
- Published in:
- EMBO Journal, 2000, v. 19, n. 20, p. 5567, doi. 10.1093/emboj/19.20.5567
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- Publication type:
- Article
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin.
- Published in:
- EMBO Journal, 2000, v. 19, n. 16, p. 4292, doi. 10.1093/emboj/19.16.4292
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- Publication type:
- Article