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Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops.
Published in:
Diabetologia, 2023, v. 66, n. 5, p. 897, doi. 10.1007/s00125-023-05877-9
By:
- Marzinotto, Ilaria;
- Pittman, David L.;
- Williams, Alistair J. K.;
- Long, Anna E.;
- Achenbach, Peter;
- Schlosser, Michael;
- Akolkar, Beena;
- Winter, William E.;
- Lampasona, Vito
Publication type:
Article
Type 1 diabetes in Africa: an immunogenetic study in the Amhara of North-West Ethiopia.
Published in:
Diabetologia, 2020, v. 63, n. 10, p. 2158, doi. 10.1007/s00125-020-05229-x
By:
- Balcha, Shitaye A.;
- Demisse, Abayneh G.;
- Mishra, Rajashree;
- Vartak, Tanwi;
- Cousminer, Diana L.;
- Hodge, Kenyaita M.;
- Voight, Benjamin F.;
- Lorenz, Kim;
- Schwartz, Stanley;
- Jerram, Samuel T.;
- Gamper, Arla;
- Holmes, Alice;
- Wilson, Hannah F.;
- Williams, Alistair J. K.;
- Grant, Struan F. A.;
- Leslie, R. David;
- Phillips, David I. W.;
- Trimble, Elisabeth R.
Publication type:
Article
Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.
Published in:
Diabetologia, 2020, v. 63, n. 6, p. 1174, doi. 10.1007/s00125-020-05114-7
By:
- Hanna, Stephanie J.;
- Powell, Wendy E.;
- Long, Anna E.;
- Robinson, Emma J. S.;
- Davies, Joanne;
- Megson, Clare;
- Howell, Alexandra;
- Jones, Taz J.;
- Ladell, Kristin;
- Price, David A.;
- Dayan, Colin M.;
- Williams, Alistair J. K.;
- Gillespie, Kathleen M.;
- Wong, F. Susan
Publication type:
Article
Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12.
Published in:
Diabetologia, 2018, v. 61, n. 7, p. 1644, doi. 10.1007/s00125-018-4605-3
By:
- Achenbach, Peter;
- Hawa, Mohammed I.;
- Krause, Stephanie;
- Lampasona, Vito;
- Jerram, Samuel T.;
- Williams, Alistair J. K.;
- Bonifacio, Ezio;
- Ziegler, Anette G.;
- Leslie, R. David;
- on behalf of the Action LADA consortium
Publication type:
Article
Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: the SNAIL study.
Published in:
Diabetologia, 2018, v. 61, n. 6, p. 1484, doi. 10.1007/s00125-018-4591-5
By:
- Long, Anna E.;
- Wilson, Isabel V.;
- Becker, Dorothy J.;
- Libman, Ingrid M.;
- Arena, Vincent C.;
- Wong, F. Susan;
- Steck, Andrea K.;
- Rewers, Marian J.;
- Yu, Liping;
- Achenbach, Peter;
- Casas, Rosaura;
- Ludvigsson, Johnny;
- Williams, Alistair J. K.;
- Gillespie, Kathleen M.
Publication type:
Article
The measurement of autoantibodies to insulin informs diagnosis of diabetes in a childhood population negative for other autoantibodies.
Published in:
Diabetic Medicine, 2022, v. 39, n. 12, p. 1, doi. 10.1111/dme.14979
By:
- Williams, Claire L.;
- Aitken, Rachel J.;
- Wilson, Isabel V.;
- Mortimer, Georgina L. M.;
- Long, Anna E.;
- Williams, Alistair J. K.;
- Gillespie, Kathleen M.
Publication type:
Article
Proinsulin-specific autoantibodies are relatively infrequent in young offspring with pre-type 1 diabetes.
Published in:
2001
By:
- Hummel, Michael;
- Williams, Alistair J. K.;
- Norcross, Alastair;
- Bingley, Polly J.;
- Standl, Eberhard;
- Bonifacio, Ezio;
- Ziegler, Anette G.;
- Hummel, M;
- Williams, A J;
- Norcross, A;
- Standl, E;
- Bonifacio, E;
- Ziegler, A G;
- Bingley, P J
Publication type:
Letter
The high prevalence of autoantibodies to tissue transglutaminase in first-degree relatives of patients with type 1 diabetes is not associated with islet autoimmunity.
Published in:
2001
By:
- Williams, Alistair J. K.;
- Norcross, Alastair J.;
- Lock, Robert J.;
- Unsworth, David J.;
- Gale, Edwin A. M;
- Bingley, Polly J.;
- Williams, A J;
- Norcross, A J;
- Lock, R J;
- Unsworth, D J;
- Gale, E A;
- Bingley, P J
Publication type:
journal article
Diabetes Antibody Standardization Program:First Proficiency Evaluation of Assays for Autoantibodies to Zinc Transporter 8.
Published in:
Clinical Chemistry, 2011, v. 57, n. 12, p. 1693, doi. 10.1373/clinchem.2011.170662
By:
- Lampasona, Vito;
- Schlosser, Michael;
- Mueller, Patricia W.;
- Williams, Alistair J. K.;
- Wenzlau, Janet M.;
- Hutton, John C.;
- Achenbach, Peter
Publication type:
Article
Islet Autoimmunity in Children With Down's Syndrome.
Published in:
Diabetes, 2006, v. 55, n. 11, p. 3185, doi. 10.2337/db06-0856
By:
- Gillespie, Kathleen M.;
- Dix, Rachel J.;
- Williams, Alistair J. K.;
- Newton, Richard;
- Robinson, Zoey F.;
- Bingley, Polly J.;
- Gale, Edwin A. M.;
- Shield, Julian P. H.
Publication type:
Article
Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics.
Published in:
2004
By:
- Achenbach, Peter;
- Warncke, Katharina;
- Reiter, Jürgen;
- Naserke, Heike E.;
- Williams, Alistair J. K.;
- Bingley, Polly J.;
- Bonifacio, Ezio;
- Ziegler, Anette-G.;
- Reiter, Jürgen
Publication type:
journal article
Prediction of IDDM in the General Population.
Published in:
Diabetes, 1997, v. 46, n. 11, p. 1701, doi. 10.2337/diab.46.11.1701
By:
- Bingley, Polly J.;
- Bonifacio, Ezio;
- Williams, Alistair J. K.;
- Genovese, Stefano;
- Bottazzo, Gian Franco;
- Gale, Edwin A. M.
Publication type:
Article
Increased levels of anti-BSA antibodies in children with Down syndrome.
Published in:
Frontiers in Endocrinology, 2023, v. 14, p. 01, doi. 10.3389/fendo.2023.1056925
By:
- Grace, Sian L.;
- Mortimer, Georgina L.;
- Kozhakhmetova, Aizhan;
- Leveret, Jamie;
- Newton, Richard;
- Reimand, Koit;
- Shield, Julian P. H.;
- Uibo, Raivo;
- Williams, Alistair J. K.;
- Gillespie, Kathleen M.
Publication type:
Article
Assessment and Management of Anti-Insulin Autoantibodies in Varying Presentations of Insulin Autoimmune Syndrome.
Published in:
2018
By:
- Church, David;
- Cardoso, Luís;
- Kay, Richard G;
- Williams, Claire L;
- Freudenthal, Bernard;
- Clarke, Catriona;
- Harris, Julie;
- Moorthy, Myuri;
- Karra, Efthmia;
- Gribble, Fiona M;
- Reimann, Frank;
- Burling, Keith;
- Williams, Alistair J K;
- Munir, Alia;
- Jones, T Hugh;
- Führer, Dagmar;
- Moeller, Lars C;
- Cohen, Mark;
- Khoo, Bernard;
- Halsall, David
Publication type:
journal article
A novel LIPS assay for insulin autoantibodies.
Published in:
Acta Diabetologica, 2018, v. 55, n. 3, p. 263, doi. 10.1007/s00592-017-1082-y
By:
- Liberati, Daniela;
- Wyatt, Rebecca C.;
- Brigatti, Cristina;
- Marzinotto, Ilaria;
- Ferrari, Maurizio;
- Bazzigaluppi, Elena;
- Bosi, Emanuele;
- Gillard, Ben T.;
- Gillespie, Kathleen M.;
- Gorus, Frans;
- Weets, Ilse;
- Balti, Eric;
- Piemonti, Lorenzo;
- Achenbach, Peter;
- Williams, Alistair J. K.;
- Lampasona, Vito
Publication type:
Article
Improved Specificity of Glutamate Decarboxylase 65 Autoantibody Measurement Using Luciferase-Based Immunoprecipitation System Assays.
Published in:
Diabetes, 2024, v. 73, n. 4, p. 565, doi. 10.2337/db23-0550
By:
- Wyatt, Rebecca C.;
- Grace, Sian L.;
- Brigatti, Cristina;
- Marzinotto, Ilaria;
- Gillard, Ben T.;
- Shoemark, Deborah K.;
- Chandler, Kyla;
- Achenbach, Peter;
- Piemonti, Lorenzo;
- Long, Anna E.;
- Gillespie, Kathleen M.;
- Lampasona, Vito;
- Williams, Alistair J. K.
Publication type:
Article
Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children.
Published in:
2019
By:
- Endesfelder, David;
- Wolfgang zu Castell;
- Bonifacio, Ezio;
- Rewers, Marian;
- Hagopian, William A.;
- Jin‐Xiong She;
- Lernmark, Åke;
- Toppari, Jorma;
- Vehik, Kendra;
- Williams, Alistair J. K.;
- Liping Yu;
- Akolkar, Beena;
- Krischer, Jeffrey P.;
- Ziegler, Anette-G.;
- Achenbach, Peter;
- Castell, Wolfgang Zu;
- She, Jin-Xiong;
- Yu, Liping;
- TEDDY Study Group;
- Zu Castell, Wolfgang
Publication type:
journal article
Detection of Antibodies Directed to the N-Terminal Region of GAD Is Dependent on Assay Format and Contributes to Differences in the Specificity of GAD Autoantibody Assays for Type 1 Diabetes.
Published in:
Diabetes, 2015, v. 64, n. 9, p. 3239, doi. 10.2337/db14-1693
By:
- Williams, Alistair J. K.;
- Lampasona, Vito;
- Schlosser, Michael;
- Mueller, Patricia W.;
- Pittman, David L.;
- Winter, William E.;
- Akolkar, Beena;
- Wyatt, Rebecca;
- Brigatti, Cristina;
- Krause, Stephanie;
- Achenbach, Peter
Publication type:
Article
Reactivity to N-Terminally Truncated GAD<sub>65</sub>(96-585) Identifies GAD Autoantibodies That Are More Closely Associated With Diabetes Progression in Relatives of Patients With Type 1 Diabetes.
Published in:
Diabetes, 2015, v. 64, n. 9, p. 3247, doi. 10.2337/db14-1694
By:
- Williams, Alistair J. K.;
- Lampasona, Vito;
- Wyatt, Rebecca;
- Brigatti, Cristina;
- Gillespie, Kathleen M.;
- Bingley, Polly J.;
- Achenbach, Peter
Publication type:
Article
Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes.
Published in:
Diabetes, 2015, v. 64, n. 8, p. 3017, doi. 10.2337/db14-1730
By:
- Brorsson, Caroline A.;
- Onengut, Suna;
- Wei-Min Chen;
- Wenzlau, Janet;
- Liping Yu;
- Baker, Peter;
- Williams, Alistair J. K.;
- Bingley, Polly J.;
- Hutton, John C.;
- Eisenbarth, George S.;
- Concannon, Patrick;
- Rich, Stephen S.;
- Pociot, Flemming
Publication type:
Article
Early Onset of Diabetes in the Proband Is the Major Determinant of Risk in HLA DR3-DQ2/DR4-DQ8 Siblings.
Published in:
Diabetes, 2014, v. 63, n. 3, p. 1041, doi. 10.2337/db13-0994
By:
- Gillespie, Kathleen M.;
- Aitken, Rachel J.;
- Wilson, Isabel;
- Williams, Alistair J. K.;
- Bingley, Polly J.
Publication type:
Article
Following the fate of the failing β-cell: new insights from first-phase insulin responses.
Published in:
2013
By:
- Williams, Alistair J K;
- Long, Anna E
Publication type:
journal article
Islet Autoantibody Testing: An End to the Trials and Tribulations?
Published in:
2013
By:
- Bingley, Polly J.;
- Williams, Alistair J. K.
Publication type:
Opinion
Following the Fate of the Failing β-Cell: New Insights From First-Phase Insulin Responses.
Published in:
2013
By:
- Williams, Alistair J. K.;
- Long, Anna E.
Publication type:
Opinion
Humoral Responses to Islet Antigen-2 and Zinc Transporter 8 Are Attenuated in Patients Carrying HLA-A*24 Alleles at the Onset of Type 1 Diabetes.
Published in:
Diabetes, 2013, v. 62, n. 6, p. 2067, doi. 10.2337/db12-1468
By:
- Long, Anna E.;
- Gillespie, Kathleen M.;
- Aitken, Rachel J.;
- Goode, Julia C.;
- Bingley, Polly J.;
- Williams, Alistair J. K.
Publication type:
Article
The Core Cysteines, (C909) of Islet Antigen-2 and (C945) of Islet Antigen-2β, Are Crucial to Autoantibody Binding in Type 1 Diabetes.
Published in:
Diabetes, 2013, v. 62, n. 1, p. 214, doi. 10.2337/db11-1590
By:
- Elvers, Karen T.;
- Geoghegan, Ivey;
- Shoemark, Debbie K.;
- Lampasona, Vito;
- Bingley, Polly J.;
- Williams, Alistair J. K.
Publication type:
Article

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