Works by Willenbring, Holger

Results: 20

Genomic structure and transcript variants of the human methylenetetrahydrofolate reductase gene.

Published in:

European Journal of Human Genetics, 2000, v. 8, n. 9, p. 725, doi. 10.1038/sj.ejhg.5200522

By:

Homberger, Anja;
Linnebank, Michael;
Winter, Carsten;
Willenbring, Holger;
Marquardt, Thorsten;
Harms, Erik;
Koch, Hans Georg

Publication type:

Article

Myelomonocytic cells are sufficient for therapeutic cell fusion in liver.

Published in:

Nature Medicine, 2004, v. 10, n. 7, p. 744, doi. 10.1038/nm1062

By:

Willenbring, Holger;
Bailey, Alexis S;
Foster, Mark;
Akkari, Yassmine;
Dorrell, Craig;
Olson, Susan;
Finegold, Milton;
Fleming, William H;
Grompe, Markus

Publication type:

Article

Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39311-w

By:

Groeger, Marko;
Matsuo, Koji;
Heidary Arash, Emad;
Pereira, Ashley;
Le Guillou, Dounia;
Pino, Cindy;
Telles-Silva, Kayque A.;
Maher, Jacquelyn J.;
Hsiao, Edward C.;
Willenbring, Holger

Publication type:

Article

Cholangiocarcinomas can originate from hepatocytes in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 8, p. 2911, doi. 10.1172/JCI63212

By:

Fan, Biao;
Malato, Yann;
Calvisi, Diego F.;
Naqvi, Syed;
Razumilava, Nataliya;
Ribback, Silvia;
Gores, Gregory J.;
Dombrowski, Frank;
Evert, Matthias;
Xin Chen;
Willenbring, Holger

Publication type:

Article

A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 3, p. 1097, doi. 10.1172/JCI46039

By:

Ng, Raymond;
Song, Guisheng;
Roll, Garrett R.;
Frandsen, Niels M.;
Willenbring, Holger

Publication type:

Article

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.

Published in:

2011

By:

Malato, Yann;
Naqvi, Syed;
Schürmann, Nina;
Ng, Raymond;
Wang, Bruce;
Zape, Joan;
Kay, Mark A.;
Grimm, Dirk;
Willenbring, Holger;
Schürmann, Nina

Publication type:

journal article

Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice.

Published in:

2010

By:

Espejel, Silvia;
Roll, Garrett R.;
McLaughlin, K. John;
Lee, Andrew Y.;
Zhang, Jenny Y.;
Laird, Diana J.;
Okita, Keisuke;
Yamanaka, Shinya;
Willenbring, Holger

Publication type:

journal article

Argininosuccinate lyase (ASL) deficiency: mutation analysis in 27 patients and a completed structure of the human ASL gene.

Published in:

Human Genetics, 2002, v. 111, n. 4/5, p. 350, doi. 10.1007/s00439-002-0793-4

By:

Linnebank, Michael;
Tschiedel, Eva;
Häberle, Johannes;
Linnebank, Anja;
Willenbring, Holger;
Kleijer, Wim J.;
Koch, Hans G.

Publication type:

Article

Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration.

Published in:

Cell Cycle, 2011, v. 10, n. 13, p. 2091, doi. 10.4161/cc.10.13.16360

By:

Eckardt, Sigrid;
McLaughlin, K. John;
Willenbring, Holger

Publication type:

Article

AAV8-Mediated In Vivo Overexpression of miR-155 Enhances the Protective Capacity of Genetically Attenuated Malarial Parasites.

Published in:

Molecular Therapy, 2014, v. 22, n. 12, p. 2130, doi. 10.1038/mt.2014.172

By:

Hentzschel, Franziska;
Hammerschmidt-Kamper, Christiane;
Börner, Kathleen;
Heiss, Kirsten;
Knapp, Bettina;
Sattler, Julia M;
Kaderali, Lars;
Castoldi, Mirco;
Bindman, Julia G;
Malato, Yann;
Willenbring, Holger;
Mueller, Ann-Kristin;
Grimm, Dirk

Publication type:

Article

In Vivo Genetic Selection of Renal Proximal Tubules.

Published in:

Molecular Therapy, 2006, v. 13, n. 1, p. 49, doi. 10.1016/j.ymthe.2005.09.004

By:

Held, Patrice K.;
Al-Dhalimy, Muhsen;
Willenbring, Holger;
Akkari, Yassmine;
Jiang, Shuguang;
Torimaru, Yumi;
Olson, Susan;
Fleming, William H.;
Finegold, Milton;
Grompe, Markus

Publication type:

Article

Integrated Isogenic Human Induced Pluripotent Stem Cell–Based Liver and Heart Microphysiological Systems Predict Unsafe Drug–Drug Interaction.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.667010

By:

Lee-Montiel, Felipe T.;
Laemmle, Alexander;
Charwat, Verena;
Dumont, Laure;
Lee, Caleb S.;
Huebsch, Nathaniel;
Okochi, Hideaki;
Hancock, Matthew J.;
Siemons, Brian;
Boggess, Steven C.;
Goswami, Ishan;
Miller, Evan W.;
Willenbring, Holger;
Healy, Kevin E.

Publication type:

Article

Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52258-w

By:

Qi, Lin;
Groeger, Marko;
Sharma, Aditi;
Goswami, Ishan;
Chen, Erzhen;
Zhong, Fenmiao;
Ram, Apsara;
Healy, Kevin;
Hsiao, Edward C.;
Willenbring, Holger;
Stahl, Andreas

Publication type:

Article

Cell fusion is the principal source of bone-marrow-derived hepatocytes.

Published in:

Nature, 2003, v. 422, n. 6934, p. 897, doi. 10.1038/nature01531

By:

Wang, Xin;
Willenbring, Holger;
Akkari, Yassmine;
Torimaru, Yumi;
Foster, Mark;
Al-Dhalimy, Muhsen;
Lagasse, Eric;
Finegold, Milton;
Olson, Susan;
Grompe, Markus

Publication type:

Article

Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development.

Published in:

Stem Cell Research & Therapy, 2013, v. 4, p. 1, doi. 10.1186/scrt375

By:

Mathur, Anurag;
Loskill, Peter;
SoonGweon Hong;
Jae Young Lee;
Marcus, Sivan G.;
Dumont, Laure;
Conklin, Bruce R.;
Willenbring, Holger;
Lee, Luke P.;
Healy, Kevin E.

Publication type:

Article

Delineating the Hepatocyte's Hematopoietic Fusion Partner.

Published in:

Cell Cycle, 2004, v. 3, n. 12, p. 1489, doi. 10.4161/cc.3.12.1304

By:

Willenbring, Holger;
Grompe, Markus

Publication type:

Article

Human iPSC‐Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System.

Published in:

Small, 2023, v. 19, n. 34, p. 1, doi. 10.1002/smll.202203725

By:

Qi, Lin;
Matsuo, Koji;
Pereira, Ashley;
Lee, Yue Tung;
Zhong, Fenmiao;
He, Yuchen;
Zushin, Peter‐James H.;
Gröger, Marko;
Sharma, Aditi;
Willenbring, Holger;
Hsiao, Edward C.;
Stahl, Andreas

Publication type:

Article

Addendum: A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice.

Published in:

Nature Protocols, 2014, v. 9, n. 6, p. 1, doi. 10.1038/nprot.2014.122

By:

Mitchell, Claudia;
Willenbring, Holger

Publication type:

Article

Brief Report: Parthenogenetic Embryonic Stem Cells are an Effective Cell Source for Therapeutic Liver Repopulation.

Published in:

Stem Cells, 2014, v. 32, n. 7, p. 1983, doi. 10.1002/stem.1726

By:

Espejel, Silvia;
Eckardt, Sigrid;
Harbell, Jack;
Roll, Garrett R.;
McLaughlin, K. John;
Willenbring, Holger

Publication type:

Article

Mouse liver repopulation with hepatocytes generated from human fibroblasts.

Published in:

Nature, 2014, v. 508, n. 7494, p. 93, doi. 10.1038/nature13020

By:

Zhu, Saiyong;
Rezvani, Milad;
Harbell, Jack;
Mattis, Aras N.;
Wolfe, Alan R.;
Benet, Leslie Z.;
Willenbring, Holger;
Ding, Sheng

Publication type:

Article