Works by Willcox, N.

Results: 36

Cell types required for anti-acetylcholine receptor antibody synthesis by cultured thymocytes and blood lymphocytes in myasthenia gravis.

Published in:

Clinical & Experimental Immunology, 1984, v. 58, n. 1, p. 97

By:

Willcox, H. N. A.;
Newsom-Davis, J.;
Calder, L. R.

Publication type:

Article

Greatly increased autoantibody production in myasthenia gravis by thymocyte suspensions prepared with proteolytic enzymes.

Published in:

Clinical & Experimental Immunology, 1983, v. 54, n. 2, p. 378

By:

Willcox, H. N. A.;
Newsom-Davis, J.;
Calder, L. R.

Publication type:

Article

Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1).

Published in:

Journal of Pathology, 2007, v. 211, n. 5, p. 563, doi. 10.1002/path.2141

By:

Ströbel, P;
Murumägi, A;
Klein, R;
Luster, M;
Lahti, M;
Krohn, K;
Schalke, B;
Nix, W;
Gold, R;
Rieckmann, P;
Toyka, K;
Burek, C;
Rosenwald, A;
Müller-Hermelink, HK;
Pujoll-Borrell, R;
Meager, A;
Willcox, N;
Peterson, P;
Marx, A

Publication type:

Article

Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.

Published in:

2005

By:

Leite MI;
Ströbel P;
Jones M;
Micklem K;
Moritz R;
Gold R;
Niks EH;
Berrih-Aknin S;
Scaravilli F;
Canelhas A;
Marx A;
Newsom-Davis J;
Willcox N;
Vincent A

Publication type:

Journal Article

Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis.

Published in:

2001

By:

Buckley, Camilla;
Douek, Daniel;
Newsom-Davis, John;
Vincent, Angela;
Willcox, Nicholas;
Buckley, C;
Douek, D;
Newsom-Davis, J;
Vincent, A;
Willcox, N

Publication type:

journal article

Early-onset myasthenia gravis: a recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a.

Published in:

1999

By:

Hill, Marguerite;
Beeson, David;
Moss, Paul;
Jacobson, Leslie;
Bond, Alison;
Corlett, Louise;
Newsom-Davis, John;
Vincent, Angela;
Willcox, Nick;
Hill, M;
Beeson, D;
Moss, P;
Jacobson, L;
Bond, A;
Corlett, L;
Newsom-Davis, J;
Vincent, A;
Willcox, N

Publication type:

journal article

Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells.

Published in:

Annals of Neurology, 1990, v. 28, n. 3, p. 312, doi. 10.1002/ana.410280303

By:

Sommer, N.;
Willcox, N.;
Harcourt, G. C.;
Newsom-Davis, J.

Publication type:

Article

Thymoma and paraneoplastic myasthenia gravis.

Published in:

Autoimmunity, 2010, v. 43, n. 5/6, p. 413, doi. 10.3109/08916930903555935

By:

Marx, A.;
Willcox, N.;
Leite, M. I.;
Chuang, W.-Y.;
Schalke, B.;
Nix, W.;
Ströbel, P.

Publication type:

Article

Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.

Published in:

Clinical & Experimental Immunology, 2013, v. 171, n. 3, p. 263, doi. 10.1111/cei.12024

By:

Kärner, J.;
Meager, A.;
Laan, M.;
Maslovskaja, J.;
Pihlap, M.;
Remm, A.;
Juronen, E.;
Wolff, A. S. B.;
Husebye, E. S.;
Podkrajšek, K. T.;
Bratanic, N.;
Battelino, T.;
Willcox, N.;
Peterson, P.;
Kisand, K.

Publication type:

Article

Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes.

Published in:

Clinical & Experimental Immunology, 2008, v. 154, n. 1, p. 141, doi. 10.1111/j.1365-2249.2008.03739.x

By:

Meager, A.;
Peterson, P.;
Willcox, N.

Publication type:

Article

Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis.

Published in:

Clinical & Experimental Immunology, 2003, v. 132, n. 1, p. 128, doi. 10.1046/j.1365-2249.2003.02113.x

By:

MEAGER, A.;
WADHWA, M.;
DILGER, P.;
BIRD, C.;
THORPE, R.;
NEWSOM-DAVIS, J.;
WILLCOX, N.

Publication type:

Article

IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis.

Published in:

2008

By:

Leite MI;
Jacob S;
Viegas S;
Cossins J;
Clover L;
Morgan BP;
Beeson D;
Willcox N;
Vincent A;
Leite, Maria Isabel;
Jacob, Saiju;
Viegas, Stuart;
Cossins, Judy;
Clover, Linda;
Morgan, B Paul;
Beeson, David;
Willcox, Nick;
Vincent, Angela

Publication type:

journal article

Immunoglobulin M receptors on memory cells of immunoglobulin G antibody-forming cell clones.

Published in:

European Journal of Immunology, 1976, v. 6, n. 6, p. 443, doi. 10.1002/eji.1830060612

By:

Abney, E. R.;
Keeler, K. D.;
Parkhouse, R. M. E.;
Willcox, H. N. A.

Publication type:

Article

B cell tolerance induced by polymeric antigens V. Different avidities of primed and virgin precursor cells for paucivalent antigen.

Published in:

European Journal of Immunology, 1976, v. 6, n. 5, p. 379, doi. 10.1002/eji.1830060514

By:

Willcox, H. N. A.;
Klaus, G. G. B.

Publication type:

Article

B cell tolerance induced by polymeric antigens. III. Dissociation of antibody formation and memory generation in tolerant mice.

Published in:

European Journal of Immunology, 1975, v. 5, n. 10, p. 699, doi. 10.1002/eji.1830051010

By:

Klaus, G. G. B.;
Willcox, H. N. A.

Publication type:

Article

Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. I. Recovery and escape from clonal dominance by suici resistant precursors.

Published in:

European Journal of Immunology, 1975, v. 5, n. 1, p. 58, doi. 10.1002/eji.1830050113

By:

McMichael, A. J.;
Willcox, N.

Publication type:

Article

Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. II. Follow-up of clones relatively resistant to radioactive antigen suicide when initially selected.

Published in:

European Journal of Immunology, 1975, v. 5, n. 2, p. 131, doi. 10.1002/eji.1830050212

By:

Willcox, H. N. A.;
McMichael, A. J.

Publication type:

Article

Thymus, Thymoma, and Specific T Cells in Myasthenia Gravisa.

Published in:

Annals of the New York Academy of Sciences, 1998, v. 841, n. 1, p. 371, doi. 10.1111/j.1749-6632.1998.tb10950.x

By:

BEESON, D.;
BOND, A. P.;
CORLETT, L.;
CURNOW, S. J.;
HILL, M. E.;
JACOBSON, L. W.;
MACLENNAN, C.;
MEAGER, A.;
MOODY, A-M.;
MOSS, P.;
NAGVEKAR, N.;
NEWSOM-DAVIS, J.;
PANTIC, N.;
ROXANIS, I.;
SPACK, E.G.;
VINCENT, A.;
WILLCOX, N.

Publication type:

Article

Muscle Nicotinic Acetylcholine Receptor mRNA Expression in Hyperplastic and Neoplastic Myasthenia Gravis Thymusa.

Published in:

Annals of the New York Academy of Sciences, 1998, v. 841, n. 1, p. 407, doi. 10.1111/j.1749-6632.1998.tb10954.x

By:

MacLENNAN, C. A.;
BEESON, D.;
WILLCOX, N;
VINCENT, A.;
NEWSOM-DAVIS, J.

Publication type:

Article

Production of Fab Fragments against the Human Acetylcholine Receptor from Myasthenia Gravis Thymus Lambda and Kappa Phage Librariesa.

Published in:

Annals of the New York Academy of Sciences, 1998, v. 841, n. 1, p. 418, doi. 10.1111/j.1749-6632.1998.tb10957.x

By:

MATTHEWS, I.;
FARRAR, J.;
McLACHLAN, S.;
RAPOPORT, B.;
NEWSOM-DAVIS, J.;
WILLCOX, N.;
VINCENT, A.

Publication type:

Article

Presentation of endogenous acetylcholine receptor antigen to a specific CD4+ T-cell line by a transfected B-cell line.

Published in:

Immunology, 1995, v. 86, n. 1, p. 116

By:

Mulcahy, A. F.;
Beeson, D. M. W.;
Willcox, N.;
Diamond, A. G.

Publication type:

Article

Greatly improved recovery of in vitro B-memory cell function after enzymic dispersion of immunized mouse spleens.

Published in:

Immunology, 1991, v. 74, n. 4, p. 600

By:

Brown, A. N.;
Willcox, H. N. A.

Publication type:

Article

Scenarios for Autoimmunization of T and B Cells in Myasthenia Gravis.

Published in:

Annals of the New York Academy of Sciences, 2003, v. 998, n. 1, p. 237, doi. 10.1196/annals.1254.026

By:

SHIONO, H.;
ROXANIS, I.;
ZHANG, W.;
SIMS, G. P.;
MEAGER, A.;
JACOBSON, L. W.;
LIU, J-L.;
MATTHEWS, I.;
WONG, Y-L.;
BONIFATI, M.;
MICKLEM, K.;
STOTT, D. I.;
TODD, J. A.;
BEESON, D.;
VINCENT, A.;
WILLCOX, N.

Publication type:

Article

Spontaneous production of anti-IFN-α and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor.

Published in:

International Immunology, 2003, v. 15, n. 8, p. 903

By:

N. Willcox;
H. Shiono;
Y.L. Wong;
I. Matthews;
J-L. Liu;
W. Zhang;
G. Sims;
A. Meager;
D. Beeson;
A. Vincent

Publication type:

Article

An in Vitro Model for Disease-specific Immunotherapy in Myasthenia Gravis Using Soluble MHC Class II Bound to AChR-derived Peptidea.

Published in:

Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 577, doi. 10.1111/j.1749-6632.1993.tb22946.x

By:

NICOLLE, M. W.;
VINCENT, A.;
SHARMA, S.;
NAG, B.;
WILLCOX, N.;
NEWSOM-DAVIS, J.

Publication type:

Article

Differential Recognition by T Cells of the P3A+ and P3A- Isoforms of the Human Acetylcholine Receptor Alpha-Subunit.

Published in:

Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 280, doi. 10.1111/j.1749-6632.1993.tb22894.x

By:

BATOCCHI, A-P.;
HARCOURT, G.;
BEESON, D.;
PANTIC, N.;
HAWKE, S.;
WILLCOX, N.;
NEWSOM-DAVIS, J.

Publication type:

Article

Stimulation of Specific T Cells by Human A ChR Adsorbed to Immunomagnetic Particles.

Published in:

Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 288, doi. 10.1111/j.1749-6632.1993.tb22897.x

By:

HAWKE, S.;
WILLCOX, N.;
HARCOURT, G.;
VINCENT, A.;
NEWSOM-DAVIS, J.

Publication type:

Article

Approaches for Studying the Pathogenic T Cells in Autoimmune Patientsa.

Published in:

Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 219, doi. 10.1111/j.1749-6632.1993.tb22888.x

By:

WILLCOX, N.;
BAGGI, F.;
BATOCCHI, A-P.;
BEESON, D.;
HARCOURT, G.;
HAWKE, S.;
JACOBSON, L.;
MATSUO, H.;
MOODY, A-M.;
NAGVEKAR, N.;
NICOLLE, M.;
ONG, B.;
PANTIC, N.;
NEWSOM-DAVIS, J.;
VINCENT, A.

Publication type:

Article

Blood and Thymic Lymphocyte Responses to Peptide Sequences of the Acetylcholine Receptor in Myasthenia Gravis.

Published in:

Annals of the New York Academy of Sciences, 1988, v. 540, n. 1, p. 354, doi. 10.1111/j.1749-6632.1988.tb27097.x

By:

HARCOURT, G.;
SOMMER, N.;
ROTHBARD, J.;
BEESON, D.;
WILLCOX, N.;
NEWSOM-DAVIS, J.

Publication type:

Article

Thymoma-An Expanded Cortical Epithelial Subset?

Published in:

Annals of the New York Academy of Sciences, 1987, v. 505, n. 1, p. 813, doi. 10.1111/j.1749-6632.1987.tb51378.x

By:

SCHLUEP, M.;
CHRISTENSSON, B.;
WILLCOX, N.;
NEWSOM-DAVIS, J.;
JANOSSY, G.;
RITTER, M.;
SCHUURMAN, H.-J.;
BIBERFELD, P.;
MATELL, G.

Publication type:

Article

Development of an Adjuvant-Independent Model of Myasthenia Gravis in Mice.

Published in:

Annals of the New York Academy of Sciences, 1987, v. 505, n. 1, p. 806, doi. 10.1111/j.1749-6632.1987.tb51376.x

By:

JERMY, A. C.;
FISHER, C. A.;
VINCENT, A.;
WILLCOX, H. N. A.;
NEWSOM-DAVIS, J.

Publication type:

Article

Genetic Susceptibility to Myasthenia Gravis Studied by DNA Hybridization.

Published in:

Annals of the New York Academy of Sciences, 1987, v. 505, n. 1, p. 800, doi. 10.1111/j.1749-6632.1987.tb51374.x

By:

DEMAINE, A. G.;
WELSH, K. I.;
WILLCOX, N.;
NEWSOM-DAVIS, J.

Publication type:

Article

Anti-Cytokine Autoantibodies Preceding Onset of Autoimmune Polyendocrine Syndrome Type I Features in Early Childhood.

Published in:

Journal of Clinical Immunology, 2013, v. 33, n. 8, p. 1341, doi. 10.1007/s10875-013-9938-6

By:

Wolff, A. S. B.;
Sarkadi, A. K.;
Maródi, L.;
Kärner, J.;
Orlova, E.;
Oftedal, B. E. V.;
Kisand, K.;
Oláh, É.;
Meloni, A.;
Myhre, A. G.;
Husebye, E. S.;
Motaghedi, R.;
Perheentupa, J.;
Peterson, P.;
Willcox, N.;
Meager, A.

Publication type:

Article

CD45 Isoform Expression in Autoimmune Myasthenia Gravis.

Published in:

Autoimmunity, 2003, v. 36, n. 2, p. 117, doi. 10.1080/0891693031000084369

By:

Tackenberg, B.;
Nitschke, M.;
Willcox, N.;
Ziegler, A.;
Nessler, S.;
Schumm, F.;
Oertel, W.H.;
Hemmer, B.;
Sommer, N.

Publication type:

Article

Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in Sardinian patients.

Published in:

2012

By:

Meloni A;
Willcox N;
Meager A;
Atzeni M;
Wolff AS;
Husebye ES;
Furcas M;
Rosatelli MC;
Cao A;
Congia M

Publication type:

Journal Article

Thymus dependence of the antibody response to tetanus toxoid in mice.

Published in:

Clinical & Experimental Immunology, 1975, v. 22, n. 2, p. 341

By:

Willcox, H. N. A.

Publication type:

Article

Works by Willcox, N.

Cell types required for anti-acetylcholine receptor antibody synthesis by cultured thymocytes and blood lymphocytes in myasthenia gravis.

Greatly increased autoantibody production in myasthenia gravis by thymocyte suspensions prepared with proteolytic enzymes.

Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1).

Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.

Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis.

Early-onset myasthenia gravis: a recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a.

Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells.

Thymoma and paraneoplastic myasthenia gravis.

Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.

Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes.

Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis.

IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis.

Immunoglobulin M receptors on memory cells of immunoglobulin G antibody-forming cell clones.

B cell tolerance induced by polymeric antigens V. Different avidities of primed and virgin precursor cells for paucivalent antigen.

B cell tolerance induced by polymeric antigens. III. Dissociation of antibody formation and memory generation in tolerant mice.

Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. I. Recovery and escape from clonal dominance by suici resistant precursors.

Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. II. Follow-up of clones relatively resistant to radioactive antigen suicide when initially selected.

Thymus, Thymoma, and Specific T Cells in Myasthenia Gravis<sup>a</sup>.

Muscle Nicotinic Acetylcholine Receptor mRNA Expression in Hyperplastic and Neoplastic Myasthenia Gravis Thymus<sup>a</sup>.

Production of Fab Fragments against the Human Acetylcholine Receptor from Myasthenia Gravis Thymus Lambda and Kappa Phage Libraries<sup>a</sup>.

Presentation of endogenous acetylcholine receptor antigen to a specific CD4<sup>+</sup> T-cell line by a transfected B-cell line.

Greatly improved recovery of <em>in vitro</em> B-memory cell function after enzymic dispersion of immunized mouse spleens.

Scenarios for Autoimmunization of T and B Cells in Myasthenia Gravis.

Spontaneous production of anti-IFN-α and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor.

An in Vitro Model for Disease-specific Immunotherapy in Myasthenia Gravis Using Soluble MHC Class II Bound to AChR-derived Peptidea.

Differential Recognition by T Cells of the P3A<sup>+</sup> and P3A<sup>-</sup> Isoforms of the Human Acetylcholine Receptor Alpha-Subunit.

Stimulation of Specific T Cells by Human A ChR Adsorbed to Immunomagnetic Particles.

Approaches for Studying the Pathogenic T Cells in Autoimmune Patientsa.

Blood and Thymic Lymphocyte Responses to Peptide Sequences of the Acetylcholine Receptor in Myasthenia Gravis.

Thymoma-An Expanded Cortical Epithelial Subset?

Development of an Adjuvant-Independent Model of Myasthenia Gravis in Mice.

Genetic Susceptibility to Myasthenia Gravis Studied by DNA Hybridization.

Anti-Cytokine Autoantibodies Preceding Onset of Autoimmune Polyendocrine Syndrome Type I Features in Early Childhood.

CD45 Isoform Expression in Autoimmune Myasthenia Gravis.

Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in Sardinian patients.

Thymus dependence of the antibody response to tetanus toxoid in mice.