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Kontakt zwischen den β1- und β2-Segmenten von α-Synuclein inhibiert die Amyloidbildung.
- Published in:
- Angewandte Chemie, 2015, v. 127, n. 30, p. 8962, doi. 10.1002/ange.201503018
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- Publication type:
- Article
The GABARAP Co-Secretome Identified by APEX2-GABARAP Proximity Labelling of Extracellular Vesicles.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 6, p. 1468, doi. 10.3390/cells9061468
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- Publication type:
- Article
Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.
- Published in:
- PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191162
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- Publication type:
- Article
Combining Independent Drug Classes into Superior, Synergistically Acting Hybrid Molecules.
- Published in:
- Angewandte Chemie International Edition, 2010, v. 49, n. 46, p. 8743, doi. 10.1002/anie.201004437
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- Publication type:
- Article
Advancements of the sFIDA method for oligomer‐based diagnostics of neurodegenerative diseases.
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- FEBS Letters, 2018, v. 592, n. 4, p. 516, doi. 10.1002/1873-3468.12983
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- Publication type:
- Article
Multiple WW domains of Nedd4-1 undergo conformational exchange that is quenched upon peptide binding.
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- FEBS Letters, 2017, v. 591, n. 11, p. 1573, doi. 10.1002/1873-3468.12664
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- Publication type:
- Article
Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy.
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- BMC Structural Biology, 2003, v. 3, p. 3, doi. 10.1186/1472-6807-3-3
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- Publication type:
- Article
A Novel Anti-Inflammatory d-Peptide Inhibits Disease Phenotype Progression in an ALS Mouse Model.
- Published in:
- Molecules, 2021, v. 26, n. 6, p. 1590, doi. 10.3390/molecules26061590
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- Publication type:
- Article
Do We Need Anti-Prion Compounds to Treat Alzheimer's Disease?
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- Molecules, 2019, v. 24, n. 12, p. 2237, doi. 10.3390/molecules24122237
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- Publication type:
- Article
Interference with Amyloid-β Nucleation by Transient Ligand Interaction.
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- Molecules, 2019, v. 24, n. 11, p. 2129, doi. 10.3390/molecules24112129
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- Publication type:
- Article
Autophagy-Related Proteins GABARAP and LC3B Label Structures of Similar Size but Different Shape in Super-Resolution Imaging.
- Published in:
- Molecules, 2019, v. 24, n. 9, p. 1833, doi. 10.3390/molecules24091833
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- Publication type:
- Article
Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer's Disease.
- Published in:
- Molecules, 2017, v. 22, n. 10, p. 1693, doi. 10.3390/molecules22101693
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- Publication type:
- Article
Solution‐Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies.
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- ChemistryOpen, 2019, v. 8, n. 7, p. 989, doi. 10.1002/open.201900167
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- Publication type:
- Article
Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses.
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- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01765-1
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- Publication type:
- Article
Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41993-6
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- Publication type:
- Article
The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-36717-1
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- Publication type:
- Article
Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37185-3
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- Publication type:
- Article
A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-36110-y
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- Publication type:
- Article
Observing the overall rocking motion of a protein in a crystal.
- Published in:
- Nature Communications, 2015, v. 6, n. 10, p. 8361, doi. 10.1038/ncomms9361
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- Publication type:
- Article
The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.
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- Science Translational Medicine, 2021, v. 13, n. 606, p. 1, doi. 10.1126/scitranslmed.abc6184
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- Publication type:
- Article
Disrupted‐in‐schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first‐episode psychosis.
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- Psychiatry & Clinical Neurosciences, 2023, v. 77, n. 12, p. 665, doi. 10.1111/pcn.13594
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- Publication type:
- Article
Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2161, doi. 10.3390/ijms24032161
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- Publication type:
- Article
CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 8842, doi. 10.3390/ijms23168842
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- Publication type:
- Article
Oral Treatment with RD2RD2 Impedes Development of Motoric Phenotype and Delays Symptom Onset in SOD1 G93A Transgenic Mice.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 7066, doi. 10.3390/ijms22137066
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- Publication type:
- Article
PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 7062, doi. 10.3390/ijms22137062
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- Publication type:
- Article
In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6553, doi. 10.3390/ijms22126553
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- Publication type:
- Article
Lack of GABARAP-Type Proteins Is Accompanied by Altered Golgi Morphology and Surfaceome Composition.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 85, doi. 10.3390/ijms22010085
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- Publication type:
- Article
Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer's Mice with Full-blown Pathology.
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- Molecular Neurobiology, 2019, v. 56, n. 3, p. 2211, doi. 10.1007/s12035-018-1209-3
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- Publication type:
- Article
Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation.
- Published in:
- Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0049-z
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- Publication type:
- Article
Structure and dimerization properties of the plant-specific copper chaperone CCH.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-69532-y
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- Publication type:
- Article
Structural studies on tRNA acceptor stem microhelices: exchange of the discriminator base A73 for G in human tRNA<sup>Leu</sup> switches the acceptor specificity from leucine to serine possibly by decreasing the stability of the terminal G1--C72 base pair
- Published in:
- Nucleic Acids Research, 1997, v. 25, n. 22, p. 4551, doi. 10.1093/nar/25.22.4551
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- Publication type:
- Article
Application of an Amyloid Beta Oligomer Standard in the sFIDA Assay.
- Published in:
- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00008
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- Publication type:
- Article
Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation.
- Published in:
- Angewandte Chemie International Edition, 2015, v. 54, n. 30, p. 8837, doi. 10.1002/anie.201503018
- By:
- Publication type:
- Article
Probing Transient Conformational States of Proteins by Solid-State R<sub>1ρ</sub> Relaxation-Dispersion NMR Spectroscopy.
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 17, p. 4312, doi. 10.1002/anie.201311275
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- Publication type:
- Article
Frontispiece: Probing Transient Conformational States of Proteins by Solid-State R<sub>1ρ</sub> Relaxation-Dispersion NMR Spectroscopy.
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- 2014
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- Publication type:
- Other
Sequestration of a β-Hairpin for Control of α-Synuclein Aggregation.
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 16, p. 4227, doi. 10.1002/anie.201309001
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- Publication type:
- Article
Potential role of HIV-1 Nef and human M6B in HIV-associated neurological disorders.
- Published in:
- 2010
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- Publication type:
- Abstract
Structure and function of a short LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae.
- Published in:
- BMC Microbiology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/S12866-015-0365-0
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- Publication type:
- Article
The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity.
- Published in:
- AIDS Research & Therapy, 2014, v. 11, p. 1, doi. 10.1186/1742-6405-11-1
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- Publication type:
- Article
Crystal structure of a light-driven sodium pump.
- Published in:
- Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 390, doi. 10.1038/nsmb.3002
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- Publication type:
- Article
The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands.
- Published in:
- Biochemical Journal, 2021, v. 478, n. 14, p. 2793, doi. 10.1042/BCJ20210105
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- Publication type:
- Article
Safety and pharmacokinetics of the orally available antiprionic compound PRI-002: A single and multiple ascending dose phase I study.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12001
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- Publication type:
- Article
Tau protein aggregation associated with SARS-CoV-2 main protease.
- Published in:
- PLoS ONE, 2023, v. 18, n. 8, p. 1, doi. 10.1371/journal.pone.0288138
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- Publication type:
- Article
Pharmacokinetic Properties of a Novel d-Peptide Developed to be Therapeutically Active Against Toxic β-Amyloid Oligomers.
- Published in:
- Pharmaceutical Research, 2016, v. 33, n. 2, p. 328, doi. 10.1007/s11095-015-1791-2
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- Publication type:
- Article
Behavioural characterization of a new Alzheimer′s disease mouse model: Development of new models and analysis methods/behavioral models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042743
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- Publication type:
- Article
Clinical phase I data of the first orally available anti‐aβ‐prionic drug PRI‐002 that reverses behavioral and cognitive deficits, and decelerates neurodegeneration in AD animal models: Human/Human trials: Other.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038821
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- Publication type:
- Article
P4‐672: EXPLORING A POTENTIALLY DIFFERENT OR ADDITIONAL MOA FOR THE CLINICAL STAGE COMPOUND PRI‐002.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1589, doi. 10.1016/j.jalz.2019.09.038
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- Publication type:
- Article
P4‐671: DO WE NEED ANTI‐PRIONIC COMPOUNDS TO TREAT ALZHEIMER'S DISEASE?
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1588, doi. 10.1016/j.jalz.2019.09.037
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- Publication type:
- Article
O4‐02‐06: ORAL TREATMENT WITH RD2 REDUCES Aβ OLIGOMER LOAD, ENHANCES COGNITION, DECELERATES NEURODEGENERATION, REVERSES DISEASE PHENOTYPE IN OLD‐AGED TG AD MICE, AND IS SAFE IN HUMANS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1233, doi. 10.1016/j.jalz.2019.06.4751
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- Publication type:
- Article
P2‐061: Aβ‐OLIGOMER ELIMINATING D‐PEPTIDES: A RATIONAL DRUG OPTIMIZATION STRATEGY LEADS TO A HIGHER IN VITRO EFFICACY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P594, doi. 10.1016/j.jalz.2019.06.2468
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- Publication type:
- Article