Works matching AU Wilders, Ronald

Results: 52

Sodium current inhibition by nanosecond pulsed electric field (nsPEF)-fact or artifact?

Published in:

Bioelectromagnetics, 2013, v. 34, n. 2, p. 162, doi. 10.1002/bem.21754

By:

Verkerk, Arie O.;
van GinnekEN, Antoni C.G.;
Wilders, Ronald

Publication type:

Article

Effects of muscarinic receptor stimulation on Ca2+ transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 1, p. 73, doi. 10.1007/s00395-009-0048-9

By:

Borren, Marcel M. G. J.;
Verkerk, Arie O.;
Wilders, Ronald;
Hajji, Najat;
Zegers, Jan G.;
Bourier, Jan;
Tan, Hanno L.;
Verheijck, Etienne E.;
Peters, Stephan L. M.;
Alewijnse, Astrid E.;
Ravesloot, Jan-Hindrik

Publication type:

Article

Tidal volume, cardiac output and functional residual capacity determine end-tidal C02 transient during standing up in humans.

Published in:

Journal of Physiology, 2004, v. 554, n. 2, p. 579, doi. 10.1113/jphysiol.2003.056895

By:

Gisolf, Janneke;
Wilders, Ronald;
Immink, Rogier V.;
Van Lieshout, Johannes J.;
Karemaker, John M.

Publication type:

Article

Ca2+-activated Cl− current in rabbit sinoatrial node cells.

Published in:

Journal of Physiology, 2002, v. 540, n. 1, p. 105, doi. 10.1113/jphysiol.2001.013184

By:

Verkerk, Arie O.;
Wilders, Ronald;
Zegers, Jan G.;
Borren, Marcel M. G. J.;
Ravesloot, Jan H.;
Verheijck, E. Etienne

Publication type:

Article

Alleviating the Effects of Short QT Syndrome Type 3 by Allele-Specific Suppression of the KCNJ2 Mutant Allele.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13351, doi. 10.3390/ijms252413351

By:

Wilders, Ronald

Publication type:

Article

Hyperpolarization-Activated Current, Iƒ, in Mathematical Models of Rabbit Sinoatrial Node Pacemaker Cells.

Published in:

BioMed Research International, 2013, v. 2013, p. 1, doi. 10.1155/2013/872454

By:

Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

Cellular Mechanisms of Sinus Node Dysfunction in Carriers of the SCN5A -E161K Mutation and Role of the H558R Polymorphism.

Published in:

Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.01795

By:

Wilders, Ronald

Publication type:

Article

Re-Evaluation of the Action Potential Upstroke Velocity as a Measure of the Na+ Current in Cardiac Myocytes at Physiological Conditions.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015772

By:

Berecki, Géza;
Wilders, Ronald;
Jonge, Berend de;
Ginneken, Antoni C. G. van;
Verkerk, Arie O.

Publication type:

Article

Pro-arrhythmogenic potential of immature cardiomyocytes is triggered by low coupling and cluster size

Published in:

Cardiovascular Research, 2006, v. 71, n. 4, p. 704, doi. 10.1016/j.cardiores.2006.06.001

By:

de Boer, Teun P.;
van der Heyden, Marcel A.G.;
Rook, Martin B.;
Wilders, Ronald;
Broekstra, Renske;
Kok, Bart;
Vos, Marc A.;
de Bakker, Jacques M.T.;
van Veen, Toon A.B.

Publication type:

Article

Role of sequence variations in the human ether-a-go-go-related gene (HERG, KCNH2) in the Brugada syndrome

Published in:

Cardiovascular Research, 2005, v. 68, n. 3, p. 441, doi. 10.1016/j.cardiores.2005.06.027

By:

Verkerk, Arie O.;
Wilders, Ronald;
Schulze-Bahr, Eric;
Beekman, Leander;
Bhuiyan, Zahurul A.;
Bertrand, Jessica;
Eckardt, Lars;
Lin, Dongxin;
Borggrefe, Martin;
Breithardt, Günter;
Mannens, Marcel M.A.M.;
Tan, Hanno L.;
Wilde, Arthur A.M.;
Bezzina, Connie R.

Publication type:

Article

Intercellular coupling through gap junctions masks M cells in the human heart

Published in:

Cardiovascular Research, 2004, v. 62, n. 2, p. 407, doi. 10.1016/j.cardiores.2004.02.016

By:

Conrath, Chantal E.;
Wilders, Ronald;
Coronel, Ruben;
de Bakker, Jacques M.T.;
Taggart, Peter;
de Groot, Joris R.;
Opthof, Tobias

Publication type:

Article

Conduction slowing by the gap junctional uncoupler carbenoxolone

Published in:

Cardiovascular Research, 2003, v. 60, n. 2, p. 288, doi. 10.1016/j.cardiores.2003.07.004

By:

de Groot, Joris R.;
Veenstra, Thijs;
Verkerk, Arie O.;
Wilders, Ronald;
Smits, Jeroen P.P.;
Wilms-Schopman, Francien J.G.;
Wiegerinck, Rob F.;
Bourier, Jan;
Belterman, Charly N.W.;
Coronel, Ruben;
Verheijck, E. Etienne

Publication type:

Article

A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization

Published in:

Cardiovascular Research, 2003, v. 59, n. 1, p. 27, doi. 10.1016/S0008-6363(03)00342-0

By:

Bezzina, Connie R.;
Verkerk, Arie O.;
Busjahn, Andreas;
Jeron, Andreas;
Erdmann, Jeanette;
Koopmann, Tamara T.;
Bhuiyan, Zahurul A.;
Wilders, Ronald;
Mannens, Marcel M.A.M.;
Tan, Hanno L.;
Luft, Friedrich C.;
Schunkert, Heribert;
Wilde, Arthur A.M.

Publication type:

Article

Effects of cell-to-cell uncoupling and catecholamines on Purkinje and ventricular action potentials: implications for phase-1b arrhythmias.

Published in:

Cardiovascular Research, 2001, v. 51, n. 1, p. 30, doi. 10.1016/S0008-6363(01)00246-2

By:

Verkerk, Arie O;
Veldkamp, Marieke W;
Coronel, Ruben;
Wilders, Ronald;
van Ginneken, Antoni C.G

Publication type:

Article

Injury current modulates afterdepolarizations in single human ventricular cells.

Published in:

Cardiovascular Research, 2000, v. 47, n. 1, p. 124, doi. 10.1016/S0008-6363(00)00064-X

By:

Verkerk, Arie O.;
Veldkamp, Marieke W.;
de Jonge, Nicolaas;
Wilders, Ronald;
van Ginneken, Antoni C.G.

Publication type:

Article

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Type 1: A Light on Molecular Mechanisms.

Published in:

Genetics Research International, 2013, p. 1, doi. 10.1155/2013/460805

By:

Vanderschuren, Koen L. A.;
Sieverink, Tom;
Wilders, Ronald

Publication type:

Article

Toward Biological Pacing by Cellular Delivery of Hcn2/SkM1.

Published in:

Frontiers in Physiology, 2021, p. N.PAG, doi. 10.3389/fphys.2020.588679

By:

Végh, Anna M. D.;
Verkerk, Arie O.;
Cócera Ortega, Lucía;
Wang, Jianan;
Geerts, Dirk;
Klerk, Mischa;
Lodder, Kirsten;
Nobel, Ruby;
Tijsen, Anke J.;
Devalla, Harsha D.;
Christoffels, Vincent M.;
Medina-Ramírez, Max;
Smits, Anke M.;
Tan, Hanno L.;
Wilders, Ronald;
Goumans, Marie José T. H.;
Boink, Gerard J. J.

Publication type:

Article

A note on the prevalence of cardiac ion channelopathies in the sudden infant death syndrome.

Published in:

2015

By:

Wilders, Ronald

Publication type:

commentary

Pacemaker activity of the human sinoatrial node: effects of HCN4 mutations on the hyperpolarization-activated current.

Published in:

2014

By:

Verkerk, Arie O;
Wilders, Ronald

Publication type:

Journal Article

Pacemaker activity of the human sinoatrial node: effects of HCN4 mutations on the hyperpolarization-activated current.

Published in:

EP: Europace, 2014, v. 16, n. 3, p. 384, doi. 10.1093/europace/eut348

By:

Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

Acetylcholine Reduces I Kr and Prolongs Action Potentials in Human Ventricular Cardiomyocytes.

Published in:

Biomedicines, 2022, v. 10, n. 2, p. 244, doi. 10.3390/biomedicines10020244

By:

Koncz, István;
Verkerk, Arie O.;
Nicastro, Michele;
Wilders, Ronald;
Árpádffy-Lovas, Tamás;
Magyar, Tibor;
Tóth, Noémi;
Nagy, Norbert;
Madrid, Micah;
Lin, Zexu;
Efimov, Igor R.

Publication type:

Article

KV4.3 Expression Modulates NaV1.5 Sodium Current.

Published in:

Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00178

By:

Portero, Vincent;
Wilders, Ronald;
Casini, Simona;
Charpentier, Flavien;
Verkerk, Arie O.;
Remme, Carol Ann

Publication type:

Article

Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.649414

By:

Verkerk, Arie O.;
Marchal, Gerard A.;
Zegers, Jan G.;
Kawasaki, Makiri;
Driessen, Antoine H. G.;
Remme, Carol Ann;
de Groot, Joris R.;
Wilders, Ronald

Publication type:

Article

Computer modelling of the sinoatrial node.

Published in:

2007

By:

Wilders, Ronald

Publication type:

Correction Notice

Propagation of pacemaker activity.

Published in:

2007

By:

Joyner, Ronald W.;
Wilders, Ronald;
Wagner, Mary B.

Publication type:

journal article

Computer modelling of the sinoatrial node.

Published in:

2007

By:

Wilders, Ronald

Publication type:

journal article

Effects of anisotropy on the development of cardiac arrhythmias associated with focal activity.

Published in:

Pflügers Archiv: European Journal of Physiology, 2000, v. 441, n. 2/3, p. 301, doi. 10.1007/s004240000413

By:

Wilders, Ronald;
Wagner, Mary B.;
Golod, David A.;
Kumar, Rajiv;
Wang, Yang-Gan;
Goolsby, William N.;
Joyner, Ronald W.;
Jongsma, Habo J.

Publication type:

Article

The Action Potential Clamp Technique as a Tool for Risk Stratification of Sinus Bradycardia Due to Loss-of-Function Mutations in HCN4: An In Silico Exploration Based on In Vitro and In Vivo Data.

Published in:

Biomedicines, 2023, v. 11, n. 9, p. 2447, doi. 10.3390/biomedicines11092447

By:

Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

Ca2+ cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells.

Published in:

Frontiers in Physiology, 2015, v. 6, p. 1, doi. 10.3389/fphys.2015.00018

By:

Verkerk, Arie O.;
van Borren, Marcel M. G. J.;
van Ginneken, Antoni C. G.;
Wilders, Ronald

Publication type:

Article

Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1.

Published in:

Frontiers in Physiology, 2015, v. 6, p. 1, doi. 10.3389/fphys.2015.00007

By:

van Putten, Rosalie M. E. Meijer;
Mengarelli, Isabella;
Guan, Kaomei;
Zegers, Jan G.;
van Ginneken, Antoni C. G.;
Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

Effects of acetylcholine and noradrenalin on action potentials of isolated rabbit sinoatrial and atrial myocytes.

Published in:

Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00174

By:

Verkerk, Arie O.;
Geuzebroek, Guillaume S. C.;
Veldkamp, Marieke W.;
Wilders, Ronald;
Doupnik, Craig;
Quinn, T. Alexander;
Gourdie, Rob

Publication type:

Article

Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments.

Published in:

Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00168

By:

Wilders, Ronald;
Coronel, Ruben;
Verheule, Sander;
Van Rijen, Harold

Publication type:

Article

SCN10A-short gene therapy to restore conduction and protect against malignant cardiac arrhythmias.

Published in:

European Heart Journal, 2025, v. 46, n. 18, p. 1747, doi. 10.1093/eurheartj/ehaf053

By:

Wang, Jianan;
Verkerk, Arie O;
Wilders, Ronald;
Zhang, Yingnan;
Zhang, Kelly;
Prakosa, Adityo;
Rivaud, Mathilde R;
Marsman, E Madelief J;
Boender, Arie R;
Klerk, Mischa;
Fokkert, Lianne;
Jonge, Berend de;
Neef, Klaus;
Kirzner, Osne F;
Bezzina, Connie R;
Remme, Carol Ann;
Tan, Hanno L;
Boukens, Bastiaan J;
Devalla, Harsha D;
Trayanova, Natalia A

Publication type:

Article

Calcium Transient and Sodium-Calcium Exchange Current in Human versus Rabbit Sinoatrial Node Pacemaker Cells.

Published in:

Scientific World Journal, 2013, p. 1, doi. 10.1155/2013/507872

By:

Verkerk, Arie O.;
van Borren, Marcel M. G. J.;
Wilders, Ronald

Publication type:

Article

Computational analysis of the human sinus node action potential: model development and effects of mutations.

Published in:

Journal of Physiology, 2017, v. 595, n. 7, p. 2365, doi. 10.1113/JP273259

By:

Fabbri, Alan;
Fantini, Matteo;
Wilders, Ronald;
Severi, Stefano

Publication type:

Article

Dynamic clamp: a powerful tool in cardiac electrophysiology.

Published in:

Journal of Physiology, 2006, v. 576, n. 2, p. 349, doi. 10.1113/jphysiol.2006.115840

By:

Wilders, Ronald

Publication type:

Article

Long-QT syndrome-related sodium channel mutations probed by the dynamic action potential clamp technique.

Published in:

Journal of Physiology, 2006, v. 570, n. 2, p. 237, doi. 10.1113/jphysiol.2005.096578

By:

Berecki, Géza;
Zegers, Jan G.;
Bhuiyan, Zahurul A.;
Verkerk, Arie O.;
Wilders, Ronald;
Van Ginneken, Antoni C. G.

Publication type:

Article

‘Dynamic clamp’ in cardiac electrophysiology.

Published in:

2005

By:

Wilders, Ronald

Publication type:

Letter

Functional Characterization of the A414G Loss-of-Function Mutation in HCN4 Associated with Sinus Bradycardia.

Published in:

Cardiogenetics, 2023, v. 13, n. 3, p. 117, doi. 10.3390/cardiogenetics13030012

By:

Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome.

Published in:

2012

By:

Wilders, Ronald

Publication type:

Journal Article

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome.

Published in:

ISRN Cardiology, 2012, p. 1, doi. 10.5402/2012/846171

By:

Wilders, Ronald

Publication type:

Article

Human Sinoatrial Node Pacemaker Activity: Role of the Slow Component of the Delayed Rectifier K + Current, I Ks.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7264, doi. 10.3390/ijms24087264

By:

Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

The Antidepressant Paroxetine Reduces the Cardiac Sodium Current.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 1904, doi. 10.3390/ijms24031904

By:

Plijter, Ingmar S.;
Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

shRNAs Targeting a Common KCNQ1 Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 4053, doi. 10.3390/ijms23074053

By:

Cócera-Ortega, Lucía;
Wilders, Ronald;
Kamps, Selina C.;
Fabrizi, Benedetta;
Huber, Irit;
van der Made, Ingeborg;
van den Bout, Anouk;
de Vries, Dylan K.;
Gepstein, Lior;
Verkerk, Arie O.;
Pinto, Yigal M.;
Tijsen, Anke J.

Publication type:

Article

Aquaporin Channels in the Heart—Physiology and Pathophysiology.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 8, p. 2039, doi. 10.3390/ijms20082039

By:

Verkerk, Arie O.;
Lodder, Elisabeth M.;
Wilders, Ronald

Publication type:

Article

Sinus Bradycardia in Carriers of the SCN5A-1795insD Mutation: Unraveling the Mechanism through Computer Simulations.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 634, doi. 10.3390/ijms19020634

By:

Wilders, Ronald

Publication type:

Article

Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 9, p. 1873, doi. 10.3390/ijms18091873

By:

Zegers, Jan G.;
Wilders, Ronald;
Verkerk, Arie O.;
Veerman, Christiaan C.;
Mengarelli, Isabella;
Bezzina, Connie R.

Publication type:

Article

Pacemaker Activity of the Human Sinoatrial Node: An Update on the Effects of Mutations in HCN4 on the Hyperpolarization-Activated Current.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 2, p. 3071, doi. 10.3390/ijms16023071

By:

Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

Injection of IK1 through dynamic clamp can make all the difference in patch-clamp studies on hiPSC-derived cardiomyocytes.

Published in:

Frontiers in Physiology, 2023, p. 01, doi. 10.3389/fphys.2023.1326160

By:

Verkerk, Arie O.;
Wilders, Ronald

Publication type:

Article

Connexin43 orthologues in vertebrates: phylogeny from fish to man.

Published in:

Development Genes & Evolution, 2004, v. 214, n. 5, p. 261, doi. 10.1007/s00427-004-0403-7

By:

van der Heyden, Marcel A. G.;
van Eijk, Marleen;
Wilders, Ronald;
de Bakker, Jacques M. T.;
Opthof, Tobias

Publication type:

Article