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Amyloid-PET and White Matter Hyperintensities Have Independent Effects on Baseline Cognitive Function and Synergistic Effects on Longitudinal Executive Function.
- Published in:
- Brain Sciences (2076-3425), 2023, v. 13, n. 2, p. 218, doi. 10.3390/brainsci13020218
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- Publication type:
- Article
Three major effects of APOE<sup>ε4</sup> on Aβ immunotherapy induced ARIA.
- Published in:
- Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1412006
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- Publication type:
- Article
Intracranial Injection of Gammagard, a Human IVIg, Modulates the Inflammatory Response of the Brain and Lowers Aβ in APP/PS1 Mice Along a Different Time Course than Anti-Aβ Antibodies.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 23, p. 9684, doi. 10.1523/JNEUROSCI.1220-13.2013
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- Publication type:
- Article
Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related Pathology.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 30, p. 10201, doi. 10.1523/JNEUROSCI.1496-12.2012
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- Publication type:
- Article
Amyloid Reduction by Amyloid-β Vaccination Also Reduces Mouse Tau Pathology and Protects from Neuron Loss in Two Mouse Models of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 25, p. 7957, doi. 10.1523/JNEUROSCI.1339-09.2009
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- Publication type:
- Article
Progression of Amyloid Pathology to Alzheimer's Disease Pathology in an Amyloid Precursor Protein Transgenic Mouse Model by Removal of Nitric Oxide Synthase 2.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 7, p. 1537, doi. 10.1523/JNEUROSCI.5066-07.2008
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- Publication type:
- Article
Nitric oxide-mediated regulation of.
- Published in:
- Journal of Neurochemistry, 2012, v. 123, n. 5, p. 736, doi. 10.1111/jnc.12028
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- Publication type:
- Article
Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice.
- Published in:
- Journal of Neuroinflammation, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12974-015-0243-6
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- Publication type:
- Article
Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice.
- Published in:
- 2014
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- Publication type:
- journal article
Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis.
- Published in:
- Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-84
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- Publication type:
- Article
Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis.
- Published in:
- 2013
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- Publication type:
- journal article
Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence.
- Published in:
- 2011
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- Publication type:
- journal article
Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice.
- Published in:
- Journal of Neuroinflammation, 2006, v. 3, p. 11, doi. 10.1186/1742-2094-3-11
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- Publication type:
- Article
Passive immunotherapy against Aβ in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage.
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- Journal of Neuroinflammation, 2004, v. 1, p. 24, doi. 10.1186/1742-2094-1-24
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- Publication type:
- Article
Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities.
- Published in:
- 2018
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- Publication type:
- journal article
Beta-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice.
- Published in:
- Alzheimer's Research & Therapy, 2014, v. 6, n. 3, p. 1, doi. 10.1186/alzrt262
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- Publication type:
- Article
Vascular Considerations for Amyloid Immunotherapy.
- Published in:
- Current Neurology & Neuroscience Reports, 2022, v. 22, n. 11, p. 709, doi. 10.1007/s11910-022-01235-1
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- Publication type:
- Article
Mechanisms of ARIA: is it time to focus on the unique immune environment of the neurovascular unit?
- Published in:
- 2023
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- Publication type:
- Editorial
Terminally differentiated effector memory T cells associate with cognitive and AD-related biomarkers in an aging-based community cohort.
- Published in:
- Immunity & Ageing, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12979-024-00443-2
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- Publication type:
- Article
Brain arteriolosclerosis.
- Published in:
- Acta Neuropathologica, 2021, v. 141, n. 1, p. 1, doi. 10.1007/s00401-020-02235-6
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- Publication type:
- Article
White matter hyperintensities influence distal cortical β‐amyloid accumulation in default mode network pathways.
- Published in:
- Brain & Behavior, 2023, v. 13, n. 10, p. 1, doi. 10.1002/brb3.3209
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- Publication type:
- Article
Neuroinflammatory Phenotypes and Their Roles in Alzheimer's Disease.
- Published in:
- Neurodegenerative Diseases, 2014, v. 13, n. 2/3, p. 183, doi. 10.1159/000354228
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- Publication type:
- Article
Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-022-04398-2
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- Publication type:
- Article
Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2022, v. 8, n. 1, p. 1, doi. 10.1002/trc2.12368
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- Publication type:
- Article
The association of circulating amylin with β-amyloid in familial Alzheimer’s disease.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2021, v. 7, n. 1, p. 1, doi. 10.1002/trc2.12130
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- Publication type:
- Article
Plasma TDP‐43 levels are associated with neuroimaging measures of brain structure in limbic regions.
- Published in:
- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023, v. 15, n. 2, p. 1, doi. 10.1002/dad2.12437
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- Publication type:
- Article
Evaluation of blood‐based, extracellular vesicles as biomarkers for aging‐related TDP‐43 pathology.
- Published in:
- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022, v. 14, n. 1, p. 1, doi. 10.1002/dad2.12365
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- Publication type:
- Article
Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia.
- Published in:
- ASN Neuro (Sage Publications, Ltd.), 2019, v. 11, p. N.PAG, doi. 10.1177/1759091419865788
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- Publication type:
- Article
Hyperhomocysteinemia-Induced Gene Expression Changes in the Cell Types of the Brain.
- Published in:
- ASN Neuro (Sage Publications, Ltd.), 2017, v. 9, n. 6, p. 1, doi. 10.1177/1759091417742296
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- Publication type:
- Article
Reduced Efficacy of Anti-Aβ Immunotherapy in a Mouse Model of Amyloid Deposition and Vascular Cognitive Impairment Comorbidity.
- Published in:
- Journal of Neuroscience, 2016, v. 36, n. 38, p. 9896, doi. 10.1523/JNEUROSCI.1762-16.2016
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- Publication type:
- Article
Fluid biomarkers of Alzheimer's disease in the Systolic Blood Pressure Intervention Trial: Developing topics.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047258
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- Publication type:
- Article
Evaluating vascular cognitive impairment and dementia due to small‐vessel disease using plasma levels of PLGF and VEGF‐A: Biomarkers (non‐neuroimaging)/Plasma/Serum/Urine biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044576
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- Publication type:
- Article
Astrocyte activation and neurovascular function in a diet‐based model of vascular contributions to cognitive impairment and dementia (VCID): Molecular and cell biology/vascular factors.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043618
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- Publication type:
- Article
Investigation of herpesviruses in dementia patients and associated inflammatory gene modulation: Molecular and cell biology/neuroinflammation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043229
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- Publication type:
- Article
Impaired neuroinflammatory response of ApoE4 in Alzheimer's disease patients: Molecular and cell biology/neuroinflammation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041052
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- Publication type:
- Article
Hyperhomocysteinemia as a model of VCID: Development of new models and analysis methods/behavioral models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039888
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- Publication type:
- Article
P4‐186: ASSESSMENT OF PLASMA AND CSF FOR ANGIOGENIC AND INFLAMMATORY PROTEINS IN A CLINICAL COHORT OF PATIENTS WITH VASCULAR COGNITIVE IMPAIRMENT AND DEMENTIA REVEAL POTENTIAL BIOMARKERS OF DISEASE SEVERITY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1347, doi. 10.1016/j.jalz.2019.06.3848
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- Publication type:
- Article
P2‐185: CHARACTERIZING NEUROINFLAMMATORY RESPONSES IN APOLIPOPROTEIN E GENOTYPES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P647, doi. 10.1016/j.jalz.2019.06.2592
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- Publication type:
- Article
O1‐08‐01: THERAPEUTIC TARGETING OF TREM2 BY AN ACTIVATING ANTIBODY AMELIORATES AMYLOID‐BETA DEPOSITION AND IMPROVES COGNITION IN THE 5XFAD MODEL OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P214, doi. 10.1016/j.jalz.2019.06.4559
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- Publication type:
- Article
F1‐07‐02: ASTROCYTE ACTIVATION AND HIPPOCAMPAL SYNAPTIC IMPAIRMENTS IN MOUSE MODELS OF AMYLOID PATHOLOGY AND CEREBROVASCULAR DYSFUNCTION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P188, doi. 10.1016/j.jalz.2019.06.4394
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- Publication type:
- Article
DT‐02‐05: MARKVCID PHASE II: PRIORITIZED CANDIDATE SMALL VESSEL VCID BIOMARKERS SELECTED FOR INDEPENDENT MULTI‐SITE TESTING AND VALIDATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1670, doi. 10.1016/j.jalz.2018.07.014
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- Publication type:
- Article
F4‐06‐04: INSIGHTS FROM FLUID BIOMARKERS OF NEUROINFLAMMATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1392, doi. 10.1016/j.jalz.2018.06.2887
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- Publication type:
- Article
P3‐205: AN EMERGING ROLE FOR HSP27 IN VASCULAR COGNITIVE IMPAIRMENT AND DEMENTIA (VCID).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1146, doi. 10.1016/j.jalz.2018.06.1564
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- Publication type:
- Article
P2‐380: MODERATE‐SEVERE LEFT MEDIAL TEMPORAL LOBE ATROPHY IS ASSOCIATED WITH WORSE COGNITIVE TESTING SCORES IN A COMMUNITY BASED ELDERLY COHORT.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P842, doi. 10.1016/j.jalz.2018.06.1071
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- Publication type:
- Article
P2‐175: TARGETING NEUROINFLAMMATION IN THE CONTEXT OF ALZHEIMER'S DISEASE WITH COMORBID VASCULAR PATHOLOGY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P735, doi. 10.1016/j.jalz.2018.06.862
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- Publication type:
- Article
P1‐398: PARIETAL LOBE CEREBRAL MICROBLEEDS ARE ASSOCIATED WITH LOWER CEREBROSPINAL FLUID BETA AMYLOID <sub>1‐42</sub> IN PATIENTS WITH SPORADIC AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P454, doi. 10.1016/j.jalz.2018.06.406
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- Publication type:
- Article
IC‐P‐152: WMH LONGITUDINAL STUDY ANALYSIS USING DIFFERENT PROTOCOLS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P129, doi. 10.1016/j.jalz.2018.06.2219
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- Publication type:
- Article
IC‐P‐115: ELIMINATING THE SOURCES OF VARIABILITY IN A SEMI‐AUTOMATED WMH QUANTIFICATION METHOD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P99, doi. 10.1016/j.jalz.2018.06.2181
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- Publication type:
- Article
ASTROCYTE RESPONSE TO HYPERHOMOCYSTEINEMIA (HHCY).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P318, doi. 10.1016/j.jalz.2017.06.018
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- Publication type:
- Article
ASTROCYTE RESPONSE TO HYPERHOMOCYSTEINEMIA (HHCY).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P232, doi. 10.1016/j.jalz.2017.06.071
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- Publication type:
- Article