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Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination.
Published in:
2017
By:
- Bos, Lieuwe;
- Stips, Cheryl;
- Schouten, Laura;
- Vught, Lonneke;
- Wiewel, Maryse;
- Wieske, Luuk;
- Hooijdonk, Roosmarijn;
- Straat, Marleen;
- Beer, Friso;
- Glas, Gerie;
- Visser, Caroline;
- Jonge, Evert;
- Juffermans, Nicole;
- Horn, Janneke;
- Schultz, Marcus;
- Bos, Lieuwe D;
- Schouten, Laura R;
- van Vught, Lonneke A;
- Wiewel, Maryse A;
- van Hooijdonk, Roosmarijn T
Publication type:
research
Chronic antiplatelet therapy is not associated with alterations in the presentation, outcome, or host response biomarkers during sepsis: a propensity-matched analysis.
Published in:
2016
By:
- Wiewel, Maryse;
- Stoppelaar, Sacha;
- Vught, Lonneke;
- Frencken, Jos;
- Hoogendijk, Arie;
- Klein Klouwenberg, Peter;
- Horn, Janneke;
- Bonten, Marc;
- Zwinderman, Aeilko;
- Cremer, Olaf;
- Schultz, Marcus;
- Poll, Tom;
- Wiewel, Maryse A;
- de Stoppelaar, Sacha F;
- van Vught, Lonneke A;
- Frencken, Jos F;
- Hoogendijk, Arie J;
- Klein Klouwenberg, Peter M C;
- Bonten, Marc J;
- Zwinderman, Aeilko H
Publication type:
journal article
Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care.
Published in:
2017
By:
- Cranendonk, Duncan R.;
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Cremer, Olaf L.;
- Horn, Janneke;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- der Poll, Tomvan;
- Wiersinga, W. Joost;
- van der Poll, Tom
Publication type:
journal article
The leukocyte non-coding RNA landscape in critically ill patients with sepsis.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.58597
By:
- Scicluna, Brendon P.;
- Uhel, Fabrice;
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Baessman, Ingelore;
- Franitza, Marek;
- Nürnberg, Peter;
- Horn, Janneke;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- van der Poll, Tom
Publication type:
Article
Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission.
Published in:
2018
By:
- Scicluna, Brendon P.;
- Wiewel, Maryse A.;
- van Vught, Lonneke A.;
- Hoogendijk, Arie J.;
- Klarenbeek, Augustijn M.;
- Franitza, Marek;
- Toliat, Mohammad R.;
- Nürnberg, Peter;
- Horn, Janneke;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- Cremer, Olaf L.;
- van der Poll, Tom
Publication type:
Letter
The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2017, v. 196, n. 4, p. 458, doi. 10.1164/rccm.201606-1225OC
By:
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Frencken, Jos F.;
- Scicluna, Brendon P.;
- Klein Klouwenberg, Peter M. C.;
- Zwinderman, Aeilko H.;
- Lutter, Rene;
- Horn, Janneke;
- Schultz, Marcus J.;
- Bonten, Marc M. J.;
- Cremer, Olaf L.;
- van der Poll, Tom
Publication type:
Article
Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients.
Published in:
2016
By:
- van Vught, Lonneke A.;
- Scicluna, Brendon P.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Klouwenberg, Peter M. C. Klein;
- Franitza, Marek;
- Toliat, Mohammad R.;
- Nürnberg, Peter;
- Cremer, Olaf L.;
- Horn, Janneke;
- Schultz, Marcus J.;
- Bonten, Marc M. J.;
- van der Poll, Tom;
- Klein Klouwenberg, Peter M C
Publication type:
journal article
A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission.
Published in:
2015
By:
- Scicluna, Brendon P.;
- Klein Klouwenberg, Peter M. C.;
- Van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Ong, David S. Y.;
- Zwinderman, Aeilko H.;
- Franitza, Marek;
- Toliat, Mohammad R.;
- Nürnberg, Peter;
- Hoogendijk, Arie J.;
- Horn, Janneke;
- Cremer, Olaf L.;
- Schultz, Marcus J.;
- Bonten, Marc J.;
- Van der Poll, Tom
Publication type:
journal article
Impact of a Machine Learning-Based Decision Support System for Urinary Tract Infections: Prospective Observational Study in 36 Primary Care Practices.
Published in:
JMIR Medical Informatics, 2022, v. 10, n. 5, p. 1, doi. 10.2196/27795
By:
- Herter, Willem Ernst;
- Khuc, Janine;
- Cinà, Giovanni;
- Knottnerus, Bart J.;
- Numans, Mattijs E.;
- Wiewel, Maryse A.;
- Bonten, Tobias N.;
- de Bruin, Daan P.;
- van Esch, Thamar;
- Chavannes, Niels H.;
- Verheij, Robert A.
Publication type:
Article
Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients.
Published in:
2015
By:
- Hoogendijk, Arie J.;
- Wiewel, Maryse A.;
- van Vught, Lonneke A.;
- Scicluna, Brendon P.;
- Belkasim-Bohoudi, Hakima;
- Horn, Janneke;
- Zwinderman, Aeilko H.;
- Klein Klouwenberg, Peter M. C.;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- der Poll, Tom van;
- van der Poll, Tom;
- MARS consortium
Publication type:
journal article
Correction to: Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study.
Published in:
2020
By:
- Klein Klouwenberg, Peter M. C.;
- Spitoni, Cristian;
- van der Poll, Tom;
- Bonten, Marc J.;
- Cremer, Olaf L.;
- on behalf of the MARS consortium;
- Schultz, Marcus J.;
- Horn, Janneke;
- Scicluna, Brendon;
- Wiewel, Maryse A.;
- Frencken, Jos F.;
- Groep, Kirsten van de;
- Koster-Brouwer, Marlies E.;
- Ong, David S.Y.;
- Verboom, Diana;
- de Beer, Friso M.;
- Bos, Lieuwe D. J.;
- Glas, Gerie J.;
- van Hooijdonk, Roosmarijn T. M.;
- Schouten, Laura R. A.
Publication type:
journal article
Patients with hypothermic sepsis have a unique gene expression profile compared to patients with fever and sepsis.
Published in:
Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 7, p. 1896, doi. 10.1111/jcmm.17156
By:
- Harmon, Matthew B. A.;
- Scicluna, Brendon P.;
- Wiewel, Maryse A.;
- Schultz, Marcus J.;
- Horn, Janneke;
- Cremer, Olaf L.;
- van der Poll, Tom;
- Joost Wiersinga, W.;
- Juffermans, Nicole P.;
- de Beer, Friso M;
- Bos, Lieuwe D;
- Glas, Gerie J;
- Hoogendijk, Arie J;
- van Hooijdonk, Roosmarijn T;
- Huson, Mischa A;
- Scicluna, Brendon;
- Schouten, Laura R;
- Schultz, Marcus J;
- Straat, Marleen;
- van Vught, Lonneke A.
Publication type:
Article
Intracellular expression of granzymes A, B, K and M in blood lymphocyte subsets of critically ill patients with or without sepsis.
Published in:
Clinical & Experimental Immunology, 2021, v. 205, n. 2, p. 222, doi. 10.1111/cei.13601
By:
- García‐Laorden, M. Isabel;
- Hoogendijk, Arie J.;
- Wiewel, Maryse A.;
- Vught, Lonneke A.;
- Schultz, Marcus J.;
- Bovenschen, Niels;
- Vos, Alex F.;
- Poll, Tom
Publication type:
Article
The Impact of HIV Co-Infection on the Genomic Response to Sepsis.
Published in:
PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0148955
By:
- Huson, Michaëla A. M.;
- Scicluna, Brendon P.;
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Cremer, Olaf L.;
- Bonten, Marc J. M.;
- Schultz, Marcus J.;
- Franitza, Marek;
- Toliat, Mohammad R.;
- Nürnberg, Peter;
- Grobusch, Martin P.;
- van der Poll, Tom
Publication type:
Article
Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response.
Published in:
Intensive Care Medicine Experimental, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40635-019-0270-1
By:
- Schouten, Laura R. A.;
- Bos, Lieuwe D. J.;
- Serpa Neto, A.;
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Bonten, Marc J. M.;
- Cremer, Olaf L.;
- Horn, Janneke;
- van der Poll, Tom;
- Schultz, Marcus J.;
- Wösten-van Asperen, Roelie M.;
- the MARS consortium;
- de Beer, F. M.;
- Bos, L. D.;
- Glas, G. J.;
- Horn, J.;
- Hoogendijk, A. J.;
- van Hooijdonk, R. T.;
- Huson, M. A.
Publication type:
Article
Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients.
Published in:
PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0271637
By:
- Brands, Xanthe;
- Uhel, Fabrice;
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Lutter, René;
- Schultz, Marcus J.;
- Scicluna, Brendon P.;
- van der Poll, Tom
Publication type:
Article
Should we assume that hypothermia is a dysfunction in sepsis?
Published in:
2017
By:
- Steiner, Alexandre A.;
- Fonseca, Monique T.;
- Soriano, Francisco G.;
- Harmon, Matthew B.;
- Wiewel, Maryse A.;
- Wiersinga, W. Joost;
- Juffermans, Nicole P.
Publication type:
Letter
Risk factors, host response and outcome of hypothermic sepsis.
Published in:
Critical Care, 2016, v. 20, p. 1, doi. 10.1186/s13054-016-1510-3
By:
- Wiewel, Maryse A.;
- Harmon, Matthew B.;
- van Vught, Lonneke A.;
- Scicluna, Brendon P.;
- Hoogendijk, Arie J.;
- Horn, Janneke;
- Zwinderman, Aeilko H.;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- van der Poll, Tom;
- Juffermans, Nicole P.;
- Wiersinga, W. Joost
Publication type:
Article
Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study.
Published in:
2016
By:
- Wiewel, Maryse A;
- Huson, Michaëla A;
- van Vught, Lonneke A;
- Hoogendijk, Arie J;
- Klein Klouwenberg, Peter M C;
- Horn, Janneke;
- Lutter, René;
- Cremer, Olaf L;
- Schultz, Marcus J;
- Bonten, Marc J;
- van der Poll, Tom;
- MARS Consortium
Publication type:
journal article
Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study.
Published in:
Critical Care, 2016, v. 20, p. 1, doi. 10.1186/s13054-016-1469-0
By:
- Wiewel, Maryse A.;
- Huson, Michaëla A.;
- van Vught, Lonneke A.;
- Hoogendijk, Arie J.;
- Klein Klouwenberg, Peter M. C.;
- Horn, Janneke;
- Lutter, René;
- Cremer, Olaf L.;
- Schultz, Marcus J.;
- Bonten, Marc J.;
- der Poll, Tom van
Publication type:
Article
Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients.
Published in:
2016
By:
- van Vught, Lonneke A.;
- Scicluna, Brendon P.;
- Hoogendijk, Arie J.;
- Wiewel, Maryse A.;
- Klein Klouwenberg, Peter M. C.;
- Cremer, Olaf L.;
- Horn, Janneke;
- Nürnberg, Peter;
- Bonten, Marc M. J.;
- Schultz, Marcus J.;
- van der Poll, Tom
Publication type:
journal article
Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis.
Published in:
2016
By:
- van Vught, Lonneke A.;
- Klouwenberg, Peter M. C. Klein;
- Spitoni, Cristian;
- Scicluna, Brendon P.;
- Wiewel, Maryse A.;
- Horn, Janneke;
- Schultz, Marcus J.;
- Nürnberg, Peter;
- Bonten, Marc J. M.;
- Cremer, Olaf L.;
- van der Poll, Tom;
- Klein Klouwenberg, Peter M C;
- MARS Consortium
Publication type:
journal article
Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study.
Published in:
Annals of Intensive Care, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13613-019-0529-4
By:
- Schouten, Laura R.;
- van Kaam, Anton H.;
- Kohse, Franziska;
- Veltkamp, Floor;
- Bos, Lieuwe D.;
- de Beer, Friso M.;
- van Hooijdonk, Roosmarijn T.;
- Horn, Janneke;
- Straat, Marleen;
- Witteveen, Esther;
- Glas, Gerie J.;
- Wieske, Luuk;
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Ingelse, Sarah A.;
- Cortjens, Bart;
- van Woensel, Job B.;
- Bos, Albert P.;
- Walther, Thomas;
- Schultz, Marcus J.
Publication type:
Article
The host response in critically ill sepsis patients on statin therapy: a prospective observational study.
Published in:
Annals of Intensive Care, 2018, v. 8, n. 1, p. 1, doi. 10.1186/s13613-017-0349-3
By:
- Wiewel, Maryse A.;
- Scicluna, Brendon P.;
- van Vught, Lonneke A.;
- Hoogendijk, Arie J.;
- Zwinderman, Aeilko H.;
- Lutter, René;
- Horn, Janneke;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- van der Poll, Tom
Publication type:
Article

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