Found: 45
Select item for more details and to access through your institution.
Crystallographic fragment‐binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl‐CoA substrates at its active sites and a potential substrate‐channeling path between them.
- Published in:
- Acta Crystallographica: Section D, Structural Biology, 2024, v. 80, n. 8, p. 605, doi. 10.1107/S2059798324006557
- By:
- Publication type:
- Article
Managing macromolecular crystallographic data with a laboratory information management system.
- Published in:
- Acta Crystallographica: Section D, Structural Biology, 2024, v. 80, n. 8, p. 580, doi. 10.1107/S2059798324005680
- By:
- Publication type:
- Article
The EMBO biocatalysis conference “The biochemistry and chemistry of biocatalysis: from understanding to design”.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2017, v. 30, n. 3, p. 141, doi. 10.1093/protein/gzx020
- By:
- Publication type:
- Article
Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2017, v. 30, n. 3, p. 225, doi. 10.1093/protein/gzw080
- By:
- Publication type:
- Article
Structure-based directed evolution of a monomeric triosephosphate isomerase: toward a pentose sugar isomerase.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2015, v. 28, p. 187, doi. 10.1093/protein/gzv010
- By:
- Publication type:
- Article
Structure-based directed evolution of a monomeric triosephosphate isomerase: toward a pentose sugar isomerase.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2015, v. 28, n. 6, p. 187, doi. 10.1093/protein/gzv010
- By:
- Publication type:
- Article
Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2008, v. 21, n. 4, p. 257, doi. 10.1093/protein/gzn002
- By:
- Publication type:
- Article
De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions.
- Published in:
- PLoS Pathogens, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.ppat.1007116
- By:
- Publication type:
- Article
Stereoelectronic Requirements for Optimal Hydrogen-Bond-Catalyzed Enolization.
- Published in:
- Chemistry - A European Journal, 2011, v. 17, n. 10, p. 2859, doi. 10.1002/chem.201002943
- By:
- Publication type:
- Article
Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic ß-oxidation trifunctional enzyme complexes.
- Published in:
- Biochemical Journal, 2019, v. 476, n. 13, p. 1975, doi. 10.1042/BCJ20190314
- By:
- Publication type:
- Article
The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
- Published in:
- Biochemical Journal, 2019, v. 476, n. 2, p. 307, doi. 10.1042/BCJ20180788
- By:
- Publication type:
- Article
Assembly of the elongated collagen prolyl 4-hydroxylase α<sub>2</sub>β<sub>2</sub> heterotetramer around a central α<sub>2</sub> dimer.
- Published in:
- Biochemical Journal, 2017, v. 474, n. 5, p. 751, doi. 10.1042/BCJ20161000
- By:
- Publication type:
- Article
Crystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loop.
- Published in:
- Biochemical Journal, 2013, v. 455, n. 1, p. 119, doi. 10.1042/BJ20130669
- By:
- Publication type:
- Article
Structural enzymology studies with the substrate 3S‐hydroxybutanoyl‐CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD.
- Published in:
- FEBS Open Bio, 2024, v. 14, n. 4, p. 655, doi. 10.1002/2211-5463.13786
- By:
- Publication type:
- Article
17β-Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS.
- Published in:
- FASEB Journal, 2009, v. 23, n. 11, p. 3682, doi. 10.1096/fj.09-133587
- By:
- Publication type:
- Article
Structural enzymology comparisons of multifunctional enzyme, type-1 ( MFE1): the flexibility of its dehydrogenase part.
- Published in:
- FEBS Open Bio, 2017, v. 7, n. 12, p. 1830, doi. 10.1002/2211-5463.12337
- By:
- Publication type:
- Article
An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36358-7
- By:
- Publication type:
- Article
The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.
- Published in:
- EMBO Journal, 1997, v. 16, n. 24, p. 7261, doi. 10.1093/emboj/16.24.7261
- By:
- Publication type:
- Article
Crystal structure of human anterior gradient protein 3.
- Published in:
- Acta Crystallographica: Section F, Structural Biology Communications, 2018, v. 74, n. 7, p. 425, doi. 10.1107/S2053230X18009093
- By:
- Publication type:
- Article
Crystal structure of a thiolase from Escherichia coli at 1.8 Å resolution.
- Published in:
- Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 7, p. 534, doi. 10.1107/S2053230X16008451
- By:
- Publication type:
- Article
Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for l-arabinose isomerase activity.
- Published in:
- Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 6, p. 490, doi. 10.1107/S2053230X16007548
- By:
- Publication type:
- Article
Crystallization and preliminary X-ray diffraction studies of the C-terminal domain of Chlamydia trachomatis CdsD.
- Published in:
- Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 10, p. 1431, doi. 10.1107/S2053230X14019712
- By:
- Publication type:
- Article
A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
- Published in:
- Molecular Microbiology, 2014, v. 92, n. 4, p. 885, doi. 10.1111/mmi.12596
- By:
- Publication type:
- Article
The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism.
- Published in:
- Proteins, 2016, v. 84, n. 8, p. 1075, doi. 10.1002/prot.25054
- By:
- Publication type:
- Article
Atomic resolution crystallography of a complex of triosephosphate isomerase with a reaction-intermediate analog: New insight in the proton transfer reaction mechanism.
- Published in:
- Proteins, 2010, v. 78, n. 8, p. 1878, doi. 10.1002/prot.22701
- By:
- Publication type:
- Article
Inclusion of ionization states of ligands in affinity calculations.
- Published in:
- Proteins, 2009, v. 76, n. 1, p. 138, doi. 10.1002/prot.22326
- By:
- Publication type:
- Article
High resolution crystal structures of unliganded and liganded human liver ACBP reveal a new mode of binding for the acyl-CoA ligand.
- Published in:
- Proteins, 2007, v. 66, n. 1, p. 229, doi. 10.1002/prot.21124
- By:
- Publication type:
- Article
The planar conformation of a strained proline ring: A QM/MM study.
- Published in:
- Proteins, 2006, v. 64, n. 3, p. 700, doi. 10.1002/prot.21006
- By:
- Publication type:
- Article
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
- Published in:
- Nature Communications, 2014, v. 5, n. 9, p. 4805, doi. 10.1038/ncomms5805
- By:
- Publication type:
- Article
Human Δ<sup>3</sup>,Δ<sup>2</sup>-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10.
- Published in:
- FEBS Journal, 2015, v. 282, n. 4, p. 746, doi. 10.1111/febs.13179
- By:
- Publication type:
- Article
The isomerase and hydratase reaction mechanism of the crotonase active site of the multifunctional enzyme (type-1), as deduced from structures of complexes with 3 S-hydroxy-acyl- Co A.
- Published in:
- FEBS Journal, 2013, v. 280, n. 13, p. 3160, doi. 10.1111/febs.12150
- By:
- Publication type:
- Article
The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme.
- Published in:
- FEBS Journal, 2008, v. 275, n. 24, p. 6136, doi. 10.1111/j.1742-4658.2008.06737.x
- By:
- Publication type:
- Article
Structural enzymology binding studies of the peptide‐substrate‐binding domain of human collagen prolyl 4‐hydroxylase (type‐II): High affinity peptides have a PxGP sequence motif.
- Published in:
- Protein Science: A Publication of the Protein Society, 2018, v. 27, n. 9, p. 1692, doi. 10.1002/pro.3450
- By:
- Publication type:
- Article
The extended structure of the periplasmic region of CdsD, a structural protein of the type III secretion system of Chlamydia trachomatis.
- Published in:
- Protein Science: A Publication of the Protein Society, 2016, v. 25, n. 5, p. 987, doi. 10.1002/pro.2906
- By:
- Publication type:
- Article
High resolution crystal structures of triosephosphate isomerase complexed with its suicide inhibitors: The conformational flexibility of the catalytic glutamate in its closed, liganded active site.
- Published in:
- Protein Science: A Publication of the Protein Society, 2011, v. 20, n. 8, p. 1387, doi. 10.1002/pro.667
- By:
- Publication type:
- Article
ATGme: Open-source web application for rare codon identification and custom DNA sequence optimization.
- Published in:
- BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0743-5
- By:
- Publication type:
- Article
Structural studies on Δ<sup>3</sup>-Δ<sup>2</sup>-enoyl-CoA isomerase: the variable mode of assembly of the trimeric disks of the crotonase superfamily
- Published in:
- FEBS Letters, 2004, v. 557, n. 1-3, p. 81, doi. 10.1016/S0014-5793(03)01450-9
- By:
- Publication type:
- Article
The importance of the conserved Arg191–Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis
- Published in:
- FEBS Letters, 2002, v. 518, n. 1-3, p. 39, doi. 10.1016/S0014-5793(02)02639-X
- By:
- Publication type:
- Article
IceBear: an intuitive and versatile web application for research‐data tracking from crystallization experiment to PDB deposition.
- Published in:
- Acta Crystallographica: Section D, Structural Biology, 2021, v. 77, n. 2, p. 151, doi. 10.1107/S2059798320015223
- By:
- Publication type:
- Article
Selective Inhibition of Trypanosomal Triosephosphate Isomerase by a Thiopeptide.
- Published in:
- Angewandte Chemie International Edition, 1992, v. 31, n. 3, p. 328, doi. 10.1002/anie.199203281
- By:
- Publication type:
- Article
Modeling, mutagenesis, and structural studies on the fully conserved phosphate-binding loop (Loop 8) of triosephosphate isomerase: Toward a new substrate specificity.
- Published in:
- Proteins, 2001, v. 42, n. 3, p. 383, doi. 10.1002/1097-0134(20010215)42:3<383::AID-PROT80>3.0.CO;2-G
- By:
- Publication type:
- Article
The crystal structure of triosephosphate isomerase (TIM) from Thermotoga maritima: A comparative thermostability structural analysis of ten different TIM structures.
- Published in:
- Proteins, 1999, v. 37, n. 3, p. 441, doi. 10.1002/(SICI)1097-0134(19991115)37:3<441::AID-PROT11>3.0.CO;2-7
- By:
- Publication type:
- Article
Structures of the 'open' and 'closed' state of trypanosomal triosephosphate isomerase, as observed in a new crystal form: Implications for the reaction mechanism.
- Published in:
- Proteins, 1993, v. 16, n. 4, p. 311, doi. 10.1002/prot.340160402
- By:
- Publication type:
- Article
The crystal structure of the 'open' and the 'closed' conformation of the flexible loop of trypanosomal triosephosphate isomerase.
- Published in:
- Proteins, 1991, v. 10, n. 1, p. 33, doi. 10.1002/prot.340100105
- By:
- Publication type:
- Article
The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
- Published in:
- Proteins, 1991, v. 10, n. 1, p. 50, doi. 10.1002/prot.340100106
- By:
- Publication type:
- Article