Works matching AU Wiede, Florian

Results: 26

Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice.

Published in:

Diabetologia, 2016, v. 59, n. 12, p. 2632, doi. 10.1007/s00125-016-4084-3

By:

Merry, Troy;
Tran, Melanie;
Dodd, Garron;
Mangiafico, Salvatore;
Wiede, Florian;
Kaur, Supreet;
McLean, Catriona;
Andrikopoulos, Sofianos;
Tiganis, Tony

Publication type:

Article

Erratum to: Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice.

Published in:

2016

By:

Merry, Troy;
Tran, Melanie;
Dodd, Garron;
Mangiafico, Salvatore;
Wiede, Florian;
Kaur, Supreet;
McLean, Catriona;
Andrikopoulos, Sofianos;
Tiganis, Tony

Publication type:

Erratum

Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice.

Published in:

Diabetologia, 2015, v. 58, n. 1, p. 122, doi. 10.1007/s00125-014-3413-7

By:

Xi, Yannan;
Liu, Siming;
Bettaieb, Ahmed;
Matsuo, Kosuke;
Matsuo, Izumi;
Hosein, Ellen;
Chahed, Samah;
Wiede, Florian;
Zhang, Sheng;
Zhang, Zhong-Yin;
Kulkarni, Rohit;
Tiganis, Tony;
Haj, Fawaz

Publication type:

Article

Strain-Dependent Differences in Bone Development, Myeloid Hyperplasia, Morbidity and Mortality in Ptpn2-Deficient Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036703

By:

Wiede, Florian;
Sock Hui Chew;
van Vliet, Catherine;
Poulton, Ingrid J.;
Kyparissoudis, Konstantinos;
Sasmono, Tedjo;
Loh, Kim;
Tremblay, Michel L.;
Godfrey, Dale I.;
Sims, Natalie A.;
Tiganis, Tony

Publication type:

Article

PTPN2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours.

Published in:

EMBO Journal, 2020, v. 39, n. 2, p. N.PAG, doi. 10.15252/embj.2019103637

By:

Wiede, Florian;
Lu, Kun‐Hui;
Du, Xin;
Liang, Shuwei;
Hochheiser, Katharina;
Dodd, Garron T;
Goh, Pei K;
Kearney, Conor;
Meyran, Deborah;
Beavis, Paul A;
Henderson, Melissa A;
Park, Simone L;
Waithman, Jason;
Zhang, Sheng;
Zhang, Zhong‐Yin;
Oliaro, Jane;
Gebhardt, Thomas;
Darcy, Phillip K;
Tiganis, Tony

Publication type:

Article

Correction to: Pancreatic T cell protein–tyrosine phosphatase deficiency affects beta cell function in mice.

Published in:

2024

By:

Xi, Yannan;
Liu, Siming;
Bettaieb, Ahmed;
Matsuo, Kosuke;
Matsuo, Izumi;
Hosein, Ellen;
Chahed, Samah;
Wiede, Florian;
Zhang, Sheng;
Zhang, Zhong-Yin;
Kulkarni, Rohit N.;
Tiganis, Tony;
Haj, Fawaz G.

Publication type:

Correction Notice

Both Tumor Necrosis Factor Receptor Signaling Pathways Contribute to Mortality but not to Splenomegaly in Generalized Lymphoproliferative Disorder.

Published in:

Antibodies (2073-4468), 2015, v. 4, n. 1, p. 1, doi. 10.3390/antib4010001

By:

Wiede, Florian;
Roomberg, Alicia;
Darby, Jocelyn;
Gollan, Rene;
Körner, Heinrich

Publication type:

Article

A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40170-8

By:

Liang, Shuwei;
Tran, Eric;
Du, Xin;
Dong, Jiajun;
Sudholz, Harrison;
Chen, Hao;
Qu, Zihan;
Huntington, Nicholas D.;
Babon, Jeffrey J.;
Kershaw, Nadia J.;
Zhang, Zhong-Yin;
Baell, Jonathan B.;
Wiede, Florian;
Tiganis, Tony

Publication type:

Article

Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T‐Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 22, p. 1, doi. 10.1002/anie.202303818

By:

Dong, Jiajun;
Miao, Jinmin;
Miao, Yiming;
Qu, Zihan;
Zhang, Sheng;
Zhu, Peipei;
Wiede, Florian;
Jassim, Brenson A.;
Bai, Yunpeng;
Nguyen, Quyen;
Lin, Jianping;
Chen, Lan;
Tiganis, Tony;
Tao, W. Andy;
Zhang, Zhong‐Yin

Publication type:

Article

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.

Published in:

2011

By:

Wiede, Florian;
Shields, Benjamin J.;
Chew, Sock Hui;
Kyparissoudis, Konstantinos;
van Vliet, Catherine;
Galic, Sandra;
Tremblay, Michel L.;
Russell, Sarah M.;
Godfrey, Dale I.;
Tiganis, Tony

Publication type:

journal article

Stepwise progression of β-selection during T cell development involves histone deacetylation.

Published in:

Life Science Alliance, 2023, v. 6, n. 1, p. 1, doi. 10.26508/lsa.202201645

By:

Chann, Anchi S.;
Charnley, Mirren;
Newton, Lucas M.;
Newbold, Andrea;
Wiede, Florian;
Tiganis, Tony;
Humbert, Patrick O.;
Johnstone, Ricky W.;
Russell, Sarah M.

Publication type:

Article

Differential regulation of protein tyrosine kinase signalling by Dock and the PTP61F variants.

Published in:

FEBS Journal, 2017, v. 284, n. 14, p. 2231, doi. 10.1111/febs.14118

By:

Willoughby, Lee F.;
Manent, Jan;
Allan, Kirsten;
Lee, Han;
Portela, Marta;
Wiede, Florian;
Warr, Coral;
Meng, Tzu‐Ching;
Tiganis, Tony;
Richardson, Helena E.

Publication type:

Article

TCPTP Regulates SFK and STAT3 Signaling and Is Lost in Triple-Negative Breast Cancers.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 3, p. 557, doi. 10.1128/MCB.01016-12

By:

Shields, Benjamin J.;
Wiede, Florian;
Gurzov, Esteban N.;
Wee, Kenneth;
Hauser, Christine;
Hong-Jian Zhu;
Molloy, Timothy J.;
O'Toole, Sandra A.;
Daly, Roger J.;
Sutherland, Robert L.;
Mitchell, Christina A.;
McLean, Catriona A.;
Tiganis, Tony

Publication type:

Article

Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T‐Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy.

Published in:

Angewandte Chemie, 2023, v. 135, n. 22, p. 1, doi. 10.1002/ange.202303818

By:

Dong, Jiajun;
Miao, Jinmin;
Miao, Yiming;
Qu, Zihan;
Zhang, Sheng;
Zhu, Peipei;
Wiede, Florian;
Jassim, Brenson A.;
Bai, Yunpeng;
Nguyen, Quyen;
Lin, Jianping;
Chen, Lan;
Tiganis, Tony;
Tao, W. Andy;
Zhang, Zhong‐Yin

Publication type:

Article

Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.

Published in:

2019

By:

Svensson, Mattias N. D.;
Doody, Karen M.;
Schmiedel, Benjamin J.;
Bhattacharyya, Sourya;
Panwar, Bharat;
Wiede, Florian;
Yang, Shen;
Santelli, Eugenio;
Wu, Dennis J.;
Sacchetti, Cristiano;
Gujar, Ravindra;
Seumois, Gregory;
Kiosses, William B.;
Aubry, Isabelle;
Kim, Gisen;
Mydel, Piotr;
Sakaguchi, Shimon;
Kronenberg, Mitchell;
Tiganis, Tony;
Tremblay, Michel L.

Publication type:

journal article

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex.

Published in:

Nature Immunology, 2015, v. 16, n. 11, p. 1153, doi. 10.1038/ni.3271

By:

Beringer, Dennis X;
Kleijwegt, Fleur S;
Wiede, Florian;
van der Slik, Arno R;
Loh, Khai Lee;
Petersen, Jan;
Dudek, Nadine L;
Duinkerken, Gaby;
Laban, Sandra;
Joosten, Antoinette;
Vivian, Julian P;
Chen, Zhenjun;
Uldrich, Adam P;
Godfrey, Dale I;
McCluskey, James;
Price, David A;
Radford, Kristen J;
Purcell, Anthony W;
Nikolic, Tatjana;
Reid, Hugh H

Publication type:

Article

PTPN2: a tumor suppressor you want deleted?

Published in:

Immunology & Cell Biology, 2017, v. 95, n. 10, p. 859, doi. 10.1038/icb.2017.70

By:

Wiede, Florian;
Tiganis, Tony

Publication type:

Article

Early CCR6 expression on B cells modulates germinal centre kinetics and efficient antibody responses.

Published in:

Immunology & Cell Biology, 2017, v. 95, n. 1, p. 33, doi. 10.1038/icb.2016.68

By:

Reimer, Dorothea;
Lee, Adrian YS;
Bannan, Jennifer;
Fromm, Phillip;
Kara, Ervin E;
Comerford, Iain;
McColl, Shaun;
Wiede, Florian;
Mielenz, Dirk;
Körner, Heinrich

Publication type:

Article

CCR6 is transiently upregulated on B cells after activation and modulates the germinal center reaction in the mouse.

Published in:

Immunology & Cell Biology, 2013, v. 91, n. 5, p. 335, doi. 10.1038/icb.2013.14

By:

Wiede, Florian;
Fromm, Phillip D;
Comerford, Iain;
Kara, Ervin;
Bannan, Jennifer;
Schuh, Wolfgang;
Ranasinghe, Charani;
Tarlinton, David;
Winkler, Thomas;
McColl, Shaun R;
Körner, Heinrich

Publication type:

Article

TNF-dependent overexpression of CCL21 is an underlying cause of progressive lymphoaccumulation in generalized lymphoproliferative disorder.

Published in:

European Journal of Immunology, 2007, v. 37, n. 2, p. 351, doi. 10.1002/eji.200636218

By:

Wiede, Florian;
Vana, Karen;
Sedger, Lisa M.;
Lechner, Anja;
Körner, Heinrich

Publication type:

Article

PTPN2 attenuates T-cell lymphopenia-induced proliferation.

Published in:

Nature Communications, 2014, v. 5, n. 1, p. 3073, doi. 10.1038/ncomms4073

By:

Wiede, Florian;
La Gruta, Nicole L.;
Tiganis, Tony

Publication type:

Article

Pancreatic T cell protein-tyrosine phosphatase deficiency ameliorates cerulein-induced acute pancreatitis.

Published in:

Cell Communication & Signaling, 2014, v. 12, n. 1, p. 1, doi. 10.1186/1478-811X-12-13

By:

Bettaieb, Ahmed;
Yannan Xi;
Hosein, Ellen;
Coggins, Nicole;
Bachaalany, Santana;
Wiede, Florian;
Perez, Salvador;
Griffey, Stephen M.;
Sastre, Juan;
Tiganis, Tony;
Haj, Fawaz G.

Publication type:

Article

T-Cell–Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities.

Published in:

Diabetes, 2019, v. 68, n. 6, p. 1251, doi. 10.2337/db18-1362

By:

Wiede, Florian;
Brodnicki, Thomas C.;
Pei Kee Goh;
Leong, Yew A.;
Jones, Gareth W.;
Di Yu;
Baxter, Alan G.;
Jones, Simon A.;
Kay, Thomas W. H.;
Tiganis, Tony

Publication type:

Article

T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities.

Published in:

2019

By:

Wiede, Florian;
Brodnicki, Tom;
Goh, Pei Kee;
Leong, Yew A;
Jones, Gareth W;
Yu, Di;
Baxter, Alan G;
Jones, Simon A;
Kay, Tom;
Tiganis, Tony;
Brodnicki, Thomas C;
Kay, Thomas W H

Publication type:

journal article

T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis.

Published in:

Diabetes, 2010, v. 59, n. 8, p. 1906, doi. 10.2337/db09-1365

By:

Fukushima, Atsushi;
Loh, Kim;
Galic, Sandra;
Fam, Barbara;
Shields, Ben;
Wiede, Florian;
Tremblay, Michel L.;
Watt, Matthew J.;
Andrikopoulos, Sofianos;
Tiganis, Tony

Publication type:

Article

Targeting Protein Tyrosine Phosphatase 22 Does Not Enhance the Efficacy of Chimeric Antigen Receptor T Cells in Solid Tumors.

Published in:

Molecular & Cellular Biology, 2022, v. 42, n. 3, p. 1, doi. 10.1128/mcb.00449-21

By:

Xin Du;
Darcy, Phillip K.;
Wiede, Florian;
Tiganis, Tony

Publication type:

Article