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The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus.
- Published in:
- Arthritis Research & Therapy, 2018, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13075-018-1649-1
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- Publication type:
- Article
Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic b-Cells.
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- Diabetes Care, 2020, v. 43, n. 1, p. 169, doi. 10.2337/dc19-0803
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- Publication type:
- Article
Statistical Modeling of Interlocus Interactions in a Complex Disease: Rejection of the...
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- Genetics, 2001, v. 158, n. 1, p. 357, doi. 10.1093/genetics/158.1.357
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- Publication type:
- Article
Immunodominant protein epitopes II. The primary antibody response to hen egg white lysozyme requires and focuses upon a unique N-terminal epitope.
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- European Journal of Immunology, 1984, v. 14, n. 5, p. 447, doi. 10.1002/eji.1830140512
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- Publication type:
- Article
Immunodominant protein epitopes I. Induction of suppression to hen egg white lysozyme is obliterated by removal of the first three N-terminal amino acids.
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- European Journal of Immunology, 1984, v. 14, n. 5, p. 442, doi. 10.1002/eji.1830140511
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- Article
β2-Microglobulin--Deficient NOD Mice Do Not Develop Insulitis or Diabetes.
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- Diabetes, 1994, v. 43, n. 3, p. 500, doi. 10.2337/diab.43.3.500
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- Article
Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice.
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- 1986
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- Publication type:
- journal article
Suppression of B cell activation by cyclosporin A, FK506 and rapamycin.
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- European Journal of Immunology, 1990, v. 20, n. 10, p. 2277, doi. 10.1002/eji.1830201017
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- Article
Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.
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- European Journal of Immunology, 2015, v. 45, n. 11, p. 3200, doi. 10.1002/eji.201545646
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- Publication type:
- Article
The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes.
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- Database: The Journal of Biological Databases & Curation, 2013, v. 2013, p. 1, doi. 10.1093/database/bat032
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- Publication type:
- Article
Fluorescence Intensity Normalisation: Correcting for Time Effects in Large-Scale Flow Cytometric Analysis.
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- Advances in Bioinformatics, 2009, p. 1, doi. 10.1155/2009/476106
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- Publication type:
- Article
Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.
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- PLoS Genetics, 2015, v. 11, n. 6, p. 1, doi. 10.1371/journal.pgen.1005272
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- Publication type:
- Article
Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.
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- PLoS Genetics, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pgen.1005272
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- Publication type:
- Article
The Use of Idd Congenic Mice to Identify Checkpoints of Peripheral Tolerance to Islet Antigen.
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- Annals of the New York Academy of Sciences, 2007, v. 1103, p. 118, doi. 10.1196/annals.1394.003
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- Article
Islet Cell Autoimmunity and Transplantation Tolerance: Two Distinct Mechanisms?
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- Annals of the New York Academy of Sciences, 2003, v. 1005, n. 1, p. 148, doi. 10.1196/annals.1288.016
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- Publication type:
- Article
New tools for defining the 'genetic background' of inbred mouse strains.
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- Nature Immunology, 2007, v. 8, n. 7, p. 669, doi. 10.1038/ni0707-669
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- Article
Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
- Published in:
- 2022
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- Publication type:
- journal article
MHC-Linked Diabetogenic Gene in the NOD Mouse Is Not Absolutely Recessive.
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- Annals of the New York Academy of Sciences, 1988, v. 546, n. 1, p. 240, doi. 10.1111/j.1749-6632.1988.tb21653.x
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- Article
The murine type 1 diabetes loci, Idd1, Idd3, Idd5, Idd9, and Idd17/10/18, do not control thymic CD4<sup>-</sup>CD8<sup>-</sup>/TCRαβ<sup>+</sup> deficiency in the nonobese diabetic mouse.
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- Mammalian Genome, 2001, v. 12, n. 2, p. 175, doi. 10.1007/s003350010255
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- Publication type:
- Article
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis.
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- Genome Medicine, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13073-020-00756-z
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- Article
Blockade of the Programmed Death-1 (PD1) Pathway Undermines Potent Genetic Protection from Type 1 Diabetes.
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- PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089561
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- Publication type:
- Article
Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.
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- Nature Genetics, 2009, v. 41, n. 9, p. 1011, doi. 10.1038/ng.434
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- Publication type:
- Article
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.
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- Nature Genetics, 2007, v. 39, n. 9, p. 1074, doi. 10.1038/ng2102
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- Article
In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes.
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- Nature Genetics, 2006, v. 38, n. 4, p. 479, doi. 10.1038/ng1766
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- Article
QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2.
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- Nature Genetics, 1999, v. 21, n. 2, p. 158, doi. 10.1038/5941
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- Article
IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production.
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- PLoS Genetics, 2009, v. 5, n. 1, p. 1, doi. 10.1371/journal.pgen.1000322
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- Article
Development of an integrated genome informatics, data management and workflow infrastructure: A toolbox for the study of complex disease genetics.
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- Human Genomics, 2004, v. 1, n. 2, p. 98, doi. 10.1186/1479-7364-1-2-98
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- Publication type:
- Article
Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.
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- 2015
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- Publication type:
- journal article
A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes.
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- Diabetes, 2014, v. 63, n. 7, p. 2538, doi. 10.2337/db13-1777
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- Publication type:
- Article
Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5.
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- 2012
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- Publication type:
- journal article
Cellular Mechanisms of Restored b-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5.
- Published in:
- Diabetes, 2012, v. 61, n. 1, p. 166, doi. 10.2337/db11-0790
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- Publication type:
- Article
The Soluble CTLA-4 Splice Variant Protects From Type 1 Diabetes and Potentiates Regulatory T-Cell Function.
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- Diabetes, 2011, v. 60, n. 7, p. 1955, doi. 10.2337/db11-0130
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- Article
Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells.
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- 2010
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- Publication type:
- journal article
Idd9.2 and Idd9.3 Protective Alleles Function in CD4<sup>+</sup> T-Cells and Nonlymphoid Cells to Prevent Expansion of Pathogenic Islet-Specific CD8<sup>+</sup> T-Cells.
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- Diabetes, 2010, v. 59, n. 6, p. 1478, doi. 10.2337/db09-1801
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- Article
Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells.
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- 2010
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- Publication type:
- journal article
Idd9.1 Locus Controls the Suppressive Activity of FoxP3<sup>+</sup>CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T-Cells.
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- Diabetes, 2010, v. 59, n. 1, p. 272, doi. 10.2337/db09-0648
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- Publication type:
- Article
Slc11a1 Enhances the Autoimmune Diabetogenic T-Cell Response by Altering Processing and Presentation of Pancreatic Islet Antigens.
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- Diabetes, 2009, v. 58, n. 1, p. 156, doi. 10.2337/db07-1608
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- Publication type:
- Article
Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice.
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- Diabetes, 2009, v. 58, n. 1, p. 165, doi. 10.2337/db08-0275
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- Article
T1DBase: New Developments in a Type 1 Diabetes Community Website.
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- Diabetes, 2007, v. 56, p. A643
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- Publication type:
- Article
Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice.
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- 2005
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- journal article
Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3.
- Published in:
- 2004
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- Publication type:
- journal article
Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.
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- 2003
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- journal article
Insulin autoantibodies are associated with islet inflammation but not always related to diabetes progression in NOD congenic mice.
- Published in:
- 2003
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- Publication type:
- journal article
NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction.
- Published in:
- 2003
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- Publication type:
- journal article
The derivation of highly germline-competent embryonic stem cells containing NOD-derived genome.
- Published in:
- 2003
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- Publication type:
- journal article
Brief Genetics Report/ The Derivation of Highly Germline-Competent Embryonic Stem Cells Containing NOD-Derived Genome.
- Published in:
- Diabetes, 2003, v. 52, n. 1, p. 205, doi. 10.2337/diabetes.52.1.205
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- Publication type:
- Article
Mapping by genetic interaction: high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse.
- Published in:
- 2001
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- Publication type:
- journal article
NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.
- Published in:
- 2000
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- Publication type:
- journal article
Analysis of the Mouse CD30 Gene.
- Published in:
- Diabetes, 2000, v. 49, n. 9, p. 1612, doi. 10.2337/diabetes.49.9.1612
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- Publication type:
- Article
Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene.
- Published in:
- 1997
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- Publication type:
- journal article