Works by Wichterle, Hynek

Results: 29

Lineage-based identification of cellular states and expression programs.

Published in:

Bioinformatics, 2012, v. 28, n. 12, p. i250, doi. 10.1093/bioinformatics/bts204

By:

Hashimoto, Tatsunori;
Jaakkola, Tommi;
Sherwood, Richard;
Mazzoni, Esteban O.;
Wichterle, Hynek;
Gifford, David

Publication type:

Article

Young neurons from medial ganglionic eminence disperse in adult and embryonic brain.

Published in:

Nature Neuroscience, 1999, v. 2, n. 5, p. 461, doi. 10.1038/8131

By:

Wichterle, Hynek;
Garcia-Verdugo, Jose Manuel;
Herrera, Daniel G.;
Alvarez-Buylla, Arturo

Publication type:

Article

High Resolution Mapping of Enhancer-Promoter Interactions.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0122420

By:

Reeder, Christopher;
Closser, Michael;
Poh, Huay Mei;
Sandhu, Kuljeet;
Wichterle, Hynek;
Gifford, David

Publication type:

Article

Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110324

By:

Lamas, Nuno Jorge;
Johnson-Kerner, Bethany;
Roybon, Laurent;
Kim, Yoon A.;
Garcia-Diaz, Alejandro;
Wichterle, Hynek;
Henderson, Christopher E.

Publication type:

Article

Maturation of Spinal Motor Neurons Derived from Human Embryonic Stem Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040154

By:

Takazawa, Tomonori;
Croft, Gist F.;
Amoroso, Mackenzie W.;
Studer, Lorenz;
Wichterle, Hynek;
MacDermott, Amy B.

Publication type:

Article

Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific Dicer inactivation.

Published in:

Frontiers in Neuroscience, 2012, p. 1, doi. 10.3389/fnins.2012.00069

By:

Jun-An Chen;
Wichterle, Hynek;
Yanhong Shi;
Berninger, Benedikt;
Alvarez-Bolado, Gonzalo

Publication type:

Article

Functional Properties of Motoneurons Derived from Mouse Embryonic Stem Cells.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7848, doi. 10.1523/JNEUROSCI.1972-04.2004

By:

Miles, Gareth B.;
Yohn, Damien C.;
Wichterle, Hynek;
Jessell, Thomas M.;
Rafuse, Victor F.;
Brownstone, Robert M.

Publication type:

Article

Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 5, p. 1420, doi. 10.1093/hmg/ddu556

By:

Johnson-Kerner, Bethany L.;
Ahmad, Faizzan S.;
Diaz, Alejandro Garcia;
Greene, John Palmer;
Gray, Steven J.;
Samulski, Richard Jude;
Chung, Wendy K.;
Van Coster, Rudy;
Maertens, Paul;
Noggle, Scott A.;
Henderson, Christopher E.;
Wichterle, Hynek

Publication type:

Article

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33022-4

By:

Patel, Tulsi;
Hammelman, Jennifer;
Aziz, Siaresh;
Jang, Sumin;
Closser, Michael;
Michaels, Theodore L.;
Blum, Jacob A.;
Gifford, David K.;
Wichterle, Hynek

Publication type:

Article

Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 2, p. 574, doi. 10.1523/JNEUROSCI.0906-12.2013

By:

Amoroso, Mackenzie W.;
Croft, Gist F.;
Williams, Damián J.;
O'Keeffe, Sean;
Carrasco, Monica A.;
Davis, Anne R.;
Roybon, Laurent;
Oakley, Derek H.;
Maniatis, Tom;
Henderson, Christopher E.;
Wichterle, Hynek

Publication type:

Article

Concentration-Dependent Requirement for Local Protein Synthesis in Motor Neuron Subtype-Specific Response to Axon Guidance Cues.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 4, p. 1496, doi. 10.1523/JNEUROSCI.4176-11.2012

By:

Nédelec, Stéphane;
Peljto, Mirza;
Shi, Peng;
Amoroso, Mackenzie W.;
Kam, Lance C.;
Wichterle, Hynek

Publication type:

Article

Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals.

Published in:

Nature Neuroscience, 2013, v. 16, n. 9, p. 1191, doi. 10.1038/nn.3490

By:

Mazzoni, Esteban O;
Mahony, Shaun;
Peljto, Mirza;
Patel, Tulsi;
Thornton, Seraphim R;
McCuine, Scott;
Reeder, Christopher;
Boyer, Laurie A;
Young, Richard A;
Gifford, David K;
Wichterle, Hynek

Publication type:

Article

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.

Published in:

Nature Neuroscience, 2013, v. 16, n. 9, p. 1219, doi. 10.1038/nn.3467

By:

Mazzoni, Esteban O;
Mahony, Shaun;
Closser, Michael;
Morrison, Carolyn A;
Nedelec, Stephane;
Williams, Damian J;
An, Disi;
Gifford, David K;
Wichterle, Hynek

Publication type:

Article

What can pluripotent stem cells teach us about neurodegenerative diseases?

Published in:

Nature Neuroscience, 2010, v. 13, n. 7, p. 800, doi. 10.1038/nn.2577

By:

Wichterle, Hynek;
Przedborski, Serge

Publication type:

Article

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.

Published in:

Nature Neuroscience, 2007, v. 10, n. 5, p. 615, doi. 10.1038/nn1876

By:

Nagai, Makiko;
Re, Diane B;
Nagata, Tetsuya;
Chalazonitis, Alcmène;
Jessell, Thomas M;
Wichterle, Hynek;
Przedborski, Serge

Publication type:

Article

A functionally characterized test set of human induced pluripotent stem cells.

Published in:

Nature Biotechnology, 2011, v. 29, n. 3, p. 279, doi. 10.1038/nbt.1783

By:

Boulting, Gabriella L.;
Kiskinis, Evangelos;
Croft, Gist F.;
Amoroso, Mackenzie W.;
Oakley, Derek H.;
Wainger, Brian J.;
Williams, Damian J.;
Kahler, David J.;
Yamaki, Mariko;
Davidow, Lance;
Rodolfa, Christopher T.;
Dimos, John T.;
Mikkilineni, Shravani;
MacDermott, Amy B.;
Woolf, Clifford J.;
Henderson, Christopher E.;
Wichterle, Hynek;
Eggan, Kevin

Publication type:

Article

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists.

Published in:

Journal of Biology, 2002, v. 1, n. 2, p. 10, doi. 10.1186/1475-4924-1-10

By:

Frank-Kamenetsky, Maria;
Zhang, Xiaoyan M.;
Bottega, Steve;
Guicherit, Oivin;
Wichterle, Hynek;
Dudek, Henryk;
Bumcrot, David;
Wang, Frank Y.;
Jones, Simon;
Shulok, Janine;
Rubin, Lee L.;
Porter, Jeffery A.

Publication type:

Article

An Integrated Model of Multiple-Condition ChIP-Seq Data Reveals Predeterminants of Cdx2 Binding.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pcbi.1003501

By:

Mahony, Shaun;
Edwards, Matthew D.;
Mazzoni, Esteban O.;
Sherwood, Richard I.;
Kakumanu, Akshay;
Morrison, Carolyn A.;
Wichterle, Hynek;
Gifford, David K.

Publication type:

Article

Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS).

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-024-51578-1

By:

Larrea, Delfina;
Tamucci, Kirstin A.;
Kabra, Khushbu;
Velasco, Kevin R.;
Yun, Taekyung D.;
Pera, Marta;
Montesinos, Jorge;
Agrawal, Rishi R.;
Paradas, Carmen;
Smerdon, John W.;
Lowry, Emily R.;
Stepanova, Anna;
Yoval-Sanchez, Belem;
Galkin, Alexander;
Wichterle, Hynek;
Area-Gomez, Estela

Publication type:

Article

Giant axonal neuropathy: An updated perspective on its pathology and pathogenesis.

Published in:

Muscle & Nerve, 2014, v. 50, n. 4, p. 467, doi. 10.1002/mus.24321

By:

Johnson‐Kerner, Bethany L.;
Roth, Lisa;
Greene, J. Palmer;
Wichterle, Hynek;
Sproule, Douglas M.

Publication type:

Article

Embryonic stem cell-based mapping of developmental transcriptional programs.

Published in:

Nature Methods, 2011, v. 8, n. 12, p. 1056, doi. 10.1038/nmeth.1775

By:

Mazzoni, Esteban O;
Mahony, Shaun;
Iacovino, Michelina;
Morrison, Carolyn A;
Mountoufaris, George;
Closser, Michael;
Whyte, Warren A;
Young, Richard A;
Kyba, Michael;
Gifford, David K;
Wichterle, Hynek

Publication type:

Article

Constructing and deconstructing spinal motor neurons

Published in:

2012

By:

Mazzoni, Esteban O.;
Mahony, Shaun;
Morrison, Carolyn A.;
Nedelec, Stephane;
Gifford, David K.;
Wichterle, Hynek

Publication type:

Abstract

Making motor axons grow

Published in:

2012

By:

Kanning, Kevin C.;
Li, Hai;
Nikulina, Elena;
Hou, Jianwei;
Yang, Wan S.;
Kaplan, Artem;
Bermingham, John R.;
Lamas, Nuno J.;
Amoroso, Mackenzie W.;
Wichterle, Hynek;
Filbin, Marie T.;
Stockwell, Brent;
Henderson, Christopher E.

Publication type:

Abstract

High resolution discovery of chromatin interactions.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 6, p. e35, doi. 10.1093/nar/gkz051

By:

Guo, Yuchun;
Krismer, Konstantin;
Closser, Michael;
Wichterle, Hynek;
Gifford, David K

Publication type:

Article

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140157

By:

Johnson-Kerner, Bethany L.;
Garcia Diaz, Alejandro;
Ekins, Sean;
Wichterle, Hynek

Publication type:

Article

FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46110-1

By:

Savchenko, Ekaterina;
Teku, Gabriel N.;
Boza-Serrano, Antonio;
Russ, Kaspar;
Berns, Manon;
Deierborg, Tomas;
Lamas, Nuno J.;
Wichterle, Hynek;
Rothstein, Jeffrey;
Henderson, Christopher E.;
Vihinen, Mauno;
Roybon, Laurent

Publication type:

Article

β spectrin<sup>PRAGUE</sup>: a truncated β spectrin producing spectrin deficiency, defective spectrin heterodimer self-association and a phenotype of spherocytic elliptocytosis.

Published in:

British Journal of Haematology, 1995, v. 91, n. 2, p. 502, doi. 10.1111/j.1365-2141.1995.tb05330.x

By:

Jarolim, Petr;
Wichterle, Hynek;
Hanspal, Manjit;
Murray, James;
Robin, Hillard L.;
Palek, Jiri

Publication type:

Article

MicroRNA Regulation of Neural Stem Cells and Neurogenesis.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 45, p. 14931, doi. 10.1523/JNEUROSCI.4280-10.2010

By:

Yanhong Shi;
Xinyu Zhao;
Hsieh, Jenny;
Wichterle, Hynek;
Impey, Soren;
Banerjee, Sourav;
Neveu, Pierre;
Kosik, Kenneth S.

Publication type:

Article

Multiprotein Complexes of the Survival of Motor Neuron Protein SMN with Gemins Traffic to Neuronal Processes and Growth Cones of Motor Neurons.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 33, p. 8622, doi. 10.1523/JNEUROSCI.3967-05.2006

By:

Honglai Zhang;
Lei Xing;
Rossoll, Wilfried;
Wichterle, Hynek;
Singer, Robert H.;
Bassell, Gary J.

Publication type:

Article