Works by Whyte, Moira K. B.

Results: 34

The Regulation of Pulmonary Inflammation by the Hypoxia-Inducible Factor-Hydroxylase Oxygen-Sensing Pathway.

Published in:

Annals of the American Thoracic Society, 2014, v. 11, n. Supp5, p. S271, doi. 10.1513/AnnalsATS.201403-108AW

By:

Whyte, Moira K. B.;
Walmsley, Sarah R.

Publication type:

Article

Development of a Consensus Statement for the Definition, Diagnosis, and Treatment of Acute Exacerbations of Idiopathic Pulmonary Fibrosis Using the Delphi Technique.

Published in:

2015

By:

Maher, Toby;
Whyte, Moira;
Hoyles, Rachel;
Parfrey, Helen;
Ochiai, Yuuki;
Mathieson, Nicky;
Turnbull, Alice;
Williamson, Nicola;
Bennett, Bryan;
Maher, Toby M;
Whyte, Moira K B;
Hoyles, Rachel K;
Bennett, Bryan M

Publication type:

journal article

Cooperative molecular and cellular networks regulate Toll-like receptor-dependent inflammatory responses.

Published in:

FASEB Journal, 2006, v. 20, n. 12, p. 2153, doi. 10.1096/fj.06-5910fje

By:

Morris, Gavin E.;
Parker, Lisa C.;
Ward, Jon R.;
Jones, Elizabeth C.;
Whyte, Moira K. B.;
Brightling, Christopher E.;
Bradding, Peter;
Dower, Steven K.;
Sabroe, Ian

Publication type:

Article

Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection.

Published in:

FASEB Journal, 2004, v. 18, n. 10, p. 1126, doi. 10.1096/fj.03-1450fje

By:

Marriott, Helen M.;
Ali, Farzana;
Read, Robert C.;
Mitchell, Tim J.;
Whyte, Moira K. B.;
Dockrell, David H.

Publication type:

Article

Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia.

Published in:

2019

By:

Preston, Julie A;
Bewley, Martin A;
Marriott, Helen M;
McGarry Houghton, A;
Mohasin, Mohammed;
Jubrail, Jamil;
Morris, Lucy;
Stephenson, Yvonne L;
Cross, Simon;
Greaves, David R;
Craig, Ruth W;
van Rooijen, Nico;
Bingle, Colin D;
Read, Robert C;
Mitchell, Timothy J;
Whyte, Moira K B;
Shapiro, Steven D;
Dockrell, David H

Publication type:

journal article

Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.

Published in:

2017

By:

Bewley, Martin A.;
Preston, Julie A.;
Mohasin, Mohammed;
Marriott, Helen M.;
Budd, Richard C.;
Swales, Julie;
Collini, Paul;
Greaves, David R.;
Craig, Ruth W.;
Brightling, Christopher E.;
Donnelly, Louise E.;
Barnes, Peter J.;
Singh, Dave;
Shapiro, Steven D.;
Whyte, Moira K. B.;
Dockrell, David H.

Publication type:

journal article

Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163139

By:

Bewley, Martin A.;
Belchamber, Kylie B. R.;
Chana, Kirandeep K.;
Budd, Richard C.;
Donaldson, Gavin;
Wedzicha, Jadwiga A.;
Brightling, Christopher E.;
Kilty, Iain;
Donnelly, Louise E.;
Barnes, Peter J.;
Singh, Dave;
Whyte, Moira K. B.;
Dockrell, David H.;
null, null

Publication type:

Article

Targeting the Networks that Underpin Contiguous Immunity in Asthma and Chronic Obstructive Pulmonary Disease.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2007, v. 175, n. 4, p. 306, doi. 10.1164/rccm.200606-777pp

By:

Sabroe, Ian;
Parker, Lisa C.;
Dockrell, David H.;
Davies, Donna E.;
Dower, Steven K.;
Whyte, Moira K. B.

Publication type:

Article

Agonists of Toll-like Receptors 2 and 4 Activate Airway Smooth Muscle via Mononuclear Leukocytes.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2005, v. 171, n. 8, p. 814, doi. 10.1164/rccm.200403-406OC

By:

Morris, Gavin E.;
Whyte, Moira K. B.;
Martin, Gillian F.;
Jose, Peter J.;
Dower, Steven K.;
Sabroe, Ian

Publication type:

Article

Genetic Factors in Idiopathic Pulmonary Fibrosis: Transforming Growth Factor-β Implicated at Last.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2003, v. 168, n. 4, p. 410, doi. 10.1164/rccm.2306003

By:

WHYTE, MOIRA K. B.

Publication type:

Article

The Role of Toll-Like Receptors in the Regulation of Neutrophil Migration, Activation, and Apoptosis.

Published in:

Clinical Infectious Diseases, 2005, v. 41, p. S421, doi. 10.1086/431992

By:

Sabroe, Ian;
Dower, Steven K.;
Whyte, Moira K. B.

Publication type:

Article

A local circadian clock calls time on lung inflammation.

Published in:

Nature Medicine, 2014, v. 20, n. 8, p. 809, doi. 10.1038/nm.3649

By:

Thompson, A A Roger;
Walmsley, Sarah R;
Whyte, Moira K B

Publication type:

Article

Incapacitating the immune system in cystic fibrosis.

Published in:

Nature Medicine, 2007, v. 13, n. 12, p. 1417, doi. 10.1038/nm1207-1417

By:

Sabroe, Ian;
Whyte, Moira K. B.

Publication type:

Article

MODELING INFLAMMATION IN THE ZEBRAFISH: HOW A FISH CAN HELP US UNDERSTAND LUNG DISEASE.

Published in:

Experimental Lung Research, 2007, v. 33, n. 10, p. 549, doi. 10.1080/01902140701756778

By:

Renshaw, Stephen A.;
Loynes, Catherine A.;
Elworthy, Stone;
Ingham, Philip W.;
Whyte, Moira K. B.

Publication type:

Article

NEUTROPHIL APOPTOSIS IN INFECTIOUS DISEASE.

Published in:

Experimental Lung Research, 2007, v. 33, n. 10, p. 519, doi. 10.1080/01902140701756620

By:

Anwar, Sadia;
Whyte, Moira K. B.

Publication type:

Article

The role of neutrophils in cancer.

Published in:

British Medical Bulletin, 2018, v. 128, n. 1, p. 5, doi. 10.1093/bmb/ldy029

By:

Grecian, Robert;
Whyte, Moira K B;
Walmsley, Sarah R

Publication type:

Article

Implications of Apoptotic Cell Death of Resident and Recruited Cells in COPD.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2008, v. 5, n. 3, p. 143, doi. 10.1080/15412550802092894

By:

Anwar, Sadia;
Whyte, Moira K. B.

Publication type:

Article

Pannexin 1 drives efficient epithelial repair after tissue injury.

Published in:

Science Immunology, 2022, v. 7, n. 71, p. 1, doi. 10.1126/sciimmunol.abm4032

By:

Lucas, Christopher D.;
Medina, Christopher B.;
Bruton, Finnius A.;
Dorward, David A.;
Raymond, Michael H.;
Tufan, Turan;
Etchegaray, J. Iker;
Barron, Brady;
Oremek, Magdalena E. M.;
Arandjelovic, Sanja;
Farber, Emily;
Onngut-Gumuscu, Suna;
Ke, Eugene;
Whyte, Moira K. B.;
Rossi, Adriano G.;
Ravichandran, Kodi S.

Publication type:

Article

A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism.

Published in:

Science Translational Medicine, 2014, v. 6, n. 225, p. 1, doi. 10.1126/scitranslmed.3007672

By:

Robertson, Anne L.;
Holmes, Geoffrey R.;
Bojarczuk, Aleksandra N.;
Burgon, Joseph;
Loynes, Catherine A.;
Chimen, Myriam;
Sawtell, Amy K.;
Hamza, Bashar;
Willson, Joseph;
Walmsley, Sarah R.;
Anderson, Sean R.;
Coles, Mark C.;
Farrow, Stuart N.;
Solari, Roberto;
Jones, Simon;
Prince, Lynne R.;
Irimia, Daniel;
Rainger, G. Ed;
Kadirkamanathan, Visakan;
Whyte, Moira K. B.

Publication type:

Article

Drift-Diffusion Analysis of Neutrophil Migration during Inflammation Resolution in a Zebrafish Model.

Published in:

Advances in Hematology, 2012, p. 1, doi. 10.1155/2012/792163

By:

Holmes, Geoffrey R.;
Dixon, Giles;
Anderson, Sean R.;
Reyes-Aldasoro, Constantino Carlos;
Elks, Philip M.;
Billings, Stephen A.;
Whyte, Moira K. B.;
Kadirkamanathan, Visakan;
Renshaw, Stephen A.

Publication type:

Article

Pathways regulating lipopolysaccharide-induced neutrophil survival revealed by lentiviral transduction of primary human neutrophils.

Published in:

Immunology, 2009, v. 127, n. 2, p. 249, doi. 10.1111/j.1365-2567.2008.02949.x

By:

Dick, Emily P.;
Prince, Lynne R.;
Prestwich, Elizabeth C.;
Renshaw, Stephen A.;
Whyte, Moira K. B.;
Sabroe, Ian

Publication type:

Article

Regulation of human neutrophil chemokine receptor expression and function by activation of Toll-like receptors 2 and 4.

Published in:

Immunology, 2005, v. 115, n. 1, p. 90, doi. 10.1111/j.1365-2567.2005.02133.x

By:

Sabroe, Ian;
Jones, Elizabeth C.;
Whyte, Moira K. B.;
Dower, Steven K.

Publication type:

Article

Interleukin 18 receptor 1 gene polymorphisms are associated with asthma.

Published in:

European Journal of Human Genetics, 2008, v. 16, n. 9, p. 1083, doi. 10.1038/ejhg.2008.67

By:

Guohua Zhu;
Whyte, Moira K. B.;
Vestbo, Jorgen;
Carlsen, Karin;
Carlsen, Kai-Håkon;
Lenney, Warren;
Silverman, Michael;
Helms, Peter;
Pillai, Sreekumar G.

Publication type:

Article

Monocytes Regulate the Mechanism of T-cell Death by Inducing Fas-Mediated Apoptosis during Bacterial Infection.

Published in:

PLoS Pathogens, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.ppat.1002814

By:

Daigneault, Marc;
De Silva, Thushan I.;
Bewley, Martin A.;
Preston, Julie A.;
Marriott, Helen M.;
Mitchell, Andrea M.;
Mitchell, Timothy J.;
Read, Robert C.;
Whyte, Moira K. B.;
Dockrell, David H.

Publication type:

Article

A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci.

Published in:

PLoS Pathogens, 2011, v. 7, n. 1, p. 1, doi. 10.1371/journal.ppat.1001262

By:

Bewley, Martin A.;
Marriott, Helen M.;
Tulone, Calogero;
Francis, Sheila E.;
Mitchell, Timothy J.;
Read, Robert C.;
Chain, Benny;
Kroemer, Guido;
Whyte, Moira K. B.;
Dockrell, David H.

Publication type:

Article

A Method for the In Vivo Measurement of Zebrafish Tissue Neutrophil Lifespan.

Published in:

ISRN Hematology, 2012, p. 1, doi. 10.5402/2012/915868

By:

Dixon, Giles;
Elks, Philip M.;
Loynes, Catherine A.;
Whyte, Moira K. B.;
Renshaw, Stephen A.

Publication type:

Article

Staphylococcus aureus Induces Eosinophil Cell Death Mediated by α-hemolysin.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031506

By:

Prince, Lynne R.;
Graham, Kirstie J.;
Connolly, John;
Anwar, Sadia;
Ridley, Robert;
Sabroe, Ian;
Foster, Simon J.;
Whyte, Moira K. B.

Publication type:

Article

Regulation of Neutrophil Senescence by MicroRNAs.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0015810

By:

Ward, Jon R.;
Heath, Paul R.;
Catto, James W.;
Whyte, Moira K. B.;
Milo, Marta;
Renshaw, Stephen A.

Publication type:

Article

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0015768

By:

Wardle, David J.;
Burgon, Joseph;
Sabroe, Ian;
Bingle, Colin D.;
Whyte, Moira K. B.;
Renshaw, Stephen A.

Publication type:

Article

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008668

By:

Daigneault, Marc;
Preston, Julie A.;
Marriott, Helen M.;
Whyte, Moira K. B.;
Dockrell, David H.

Publication type:

Article

Identifying and hurdling obstacles to translational research.

Published in:

2007

By:

Sabroe, Ian;
Dockrell, David H.;
Vogel, Stefanie N.;
Renshaw, Stephen A.;
Whyte, Moira K. B.;
Dower, Steven K.

Publication type:

journal article

The HIF/VHL Pathway.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2008, v. 38, n. 3, p. 251, doi. 10.1165/rcmb.2007-0331TR

By:

Walmsley, Sarah R.;
McGovern, Naomi N.;
Whyte, Moira K. B.;
Chilvers, Edwin R.

Publication type:

Article

Neutrophil extracellular traps are associated with airways inflammation and increased severity of lung disease in cystic fibrosis.

Published in:

ERJ Open Research, 2024, v. 10, n. 6, p. 1, doi. 10.1183/23120541.00312-2024

By:

Law, Sheonagh M.;
Hardisty, Gareth;
Gillan, Jonathan L.;
Robinson, Nicola J.;
Davidson, Donald J.;
Whyte, Moira K. B.;
Dransfield, Ian;
Gray, Robert D.

Publication type:

Article

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.

Published in:

2011

By:

Walmsley, Sarah R.;
Chilvers, Edwin R.;
Thompson, Alfred A.;
Vaughan, Kathryn;
Marriott, Helen M.;
Parker, Lisa C.;
Shaw, Gary;
Parmar, Selina;
Schneider, Martin;
Sabroe, Ian;
Dockrell, David H.;
Milo, Marta;
Taylor, Cormac T.;
Johnson, Randall S.;
Pugh, Christopher W.;
Ratcliffe, Peter J.;
Maxwell, Patrick H.;
Carmeliet, Peter;
Whyte, Moira K. B.

Publication type:

journal article