Works by Weyden, Louise

Results: 75

Comparative genomics reveals that loss of lunatic fringe (<italic>LFNG</italic>) promotes melanoma metastasis.

Published in:

Molecular Oncology, 2018, v. 12, n. 2, p. 239, doi. 10.1002/1878-0261.12161

By:

Del Castillo Velasco‐Herrera, Martin;
van der Weyden, Louise;
Nsengimana, Jeremie;
Speak, Anneliese O.;
Sjöberg, Marcela K.;
Bishop, David Timothy;
Jönsson, Göran;
Newton‐Bishop, Julia;
Adams, David J.

Publication type:

Article

Companion canines: an under-utilised model to aid in translating anti-metastatics to the clinic.

Published in:

2020

By:

van der Weyden, Louise;
Starkey, Mike;
Abu-Helil, Bushra;
Mutsaers, Anthony J.;
Wood, Geoffrey A.

Publication type:

Editorial

Metastasis in the wild: investigating metastasis in non-laboratory animals.

Published in:

Clinical & Experimental Metastasis, 2019, v. 36, n. 1, p. 15, doi. 10.1007/s10585-019-09956-3

By:

Abu-Helil, Bushra;
van der Weyden, Louise

Publication type:

Article

Focus on Tumours in Pet Animals.

Published in:

Veterinary Sciences, 2025, v. 12, n. 3, p. 266, doi. 10.3390/vetsci12030266

By:

van der Weyden, Louise

Publication type:

Article

Pulmonary Adenocarcinoma with Cutaneous Metastasis in a Dog.

Published in:

Veterinary Sciences, 2024, v. 11, n. 7, p. 312, doi. 10.3390/vetsci11070312

By:

Greyling, Anita;
van der Weyden, Louise;
Lensink, Antonia V.;
O'Dell, Nicolize

Publication type:

Article

Clinical Use of Molecular Biomarkers in Canine and Feline Oncology: Current and Future.

Published in:

Veterinary Sciences, 2024, v. 11, n. 5, p. 199, doi. 10.3390/vetsci11050199

By:

Aupperle-Lellbach, Heike;
Kehl, Alexandra;
de Brot, Simone;
van der Weyden, Louise

Publication type:

Article

Cutaneous Plasmacytoma with Systemic Metastases in a Cape Serotine Bat (Laephotis capensis).

Published in:

Veterinary Sciences, 2024, v. 11, n. 2, p. 72, doi. 10.3390/vetsci11020072

By:

van der Weyden, Louise;
Avenant, Alida;
O'Dell, Nicolize

Publication type:

Article

Spotlight on Feline Oncology.

Published in:

Veterinary Sciences, 2023, v. 10, n. 4, p. 246, doi. 10.3390/vetsci10040246

By:

van der Weyden, Louise

Publication type:

Article

Advances in Understanding Spontaneously Occurring Melanoma in Animals.

Published in:

Veterinary Sciences, 2023, v. 10, n. 3, p. 210, doi. 10.3390/vetsci10030210

By:

Blacklock, Kelly L.;
van der Weyden, Louise

Publication type:

Article

Feline Oncogenomics: What Do We Know about the Genetics of Cancer in Domestic Cats?

Published in:

Veterinary Sciences, 2022, v. 9, n. 10, p. N.PAG, doi. 10.3390/vetsci9100547

By:

Ludwig, Latasha;
Dobromylskyj, Melanie;
Wood, Geoffrey A.;
van der Weyden, Louise

Publication type:

Article

Sinonasal Meningioma in a Siberian Tiger (Panthera tigris altaica).

Published in:

2022

By:

van der Weyden, Louise;
Caldwell, Peter;
Steyrer, Christine;
O'Dell, Nicolize;
Henning, Alischa

Publication type:

Case Study

Metastatic Uterine Adenocarcinoma in a Sable Antelope (Hippotragus niger).

Published in:

Veterinary Sciences, 2022, v. 9, n. 7, p. N.PAG, doi. 10.3390/vetsci9070339

By:

van der Weyden, Louise;
Bezuidenhout, Anien;
van Wilpe, Erna;
O'Dell, Nicolize

Publication type:

Article

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01912-w

By:

van der Weyden, Louise;
Harle, Victoria;
Turner, Gemma;
Offord, Victoria;
Iyer, Vivek;
Droop, Alastair;
Swiatkowska, Agnieszka;
Rabbie, Roy;
Campbell, Andrew D.;
Sansom, Owen J.;
Pardo, Mercedes;
Choudhary, Jyoti S.;
Ferreira, Ingrid;
Tullett, Mark;
Arends, Mark J.;
Speak, Anneliese O.;
Adams, David J.

Publication type:

Article

Computational identification of insertional mutagenesis targets for cancer gene discovery.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 15, p. e105, doi. 10.1093/nar/gkr447

By:

de Jong, Johann;
de Ridder, Jeroen;
van der Weyden, Louise;
Sun, Ning;
van Uitert, Miranda;
Berns, Anton;
van Lohuizen, Maarten;
Jonkers, Jos;
Adams, David J.;
Wessels, Lodewyk F. A.

Publication type:

Article

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.

Published in:

Nature Genetics, 2011, v. 43, n. 12, p. 1202, doi. 10.1038/ng.990

By:

March, H Nikki;
Rust, Alistair G;
Wright, Nicholas A;
ten Hoeve, Jelle;
de Ridder, Jeroen;
Eldridge, Matthew;
van der Weyden, Louise;
Berns, Anton;
Gadiot, Jules;
Uren, Anthony;
Kemp, Richard;
Arends, Mark J;
Wessels, Lodewyk F A;
Winton, Douglas J;
Adams, David J

Publication type:

Article

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.

Published in:

Nature Genetics, 2011, v. 43, n. 2, p. 147, doi. 10.1038/ng.752

By:

Crossan, Gerry P.;
van der Weyden, Louise;
Rosado, Ivan V.;
Langevin, Frederic;
Gaillard, Pierre-Henri L;
McIntyre, Rebecca E;
Gallagher, Ferdia;
Kettunen, Mikko I.;
Lewis, David Y.;
Brindle, Kevin;
Arends, Mark J.;
Adams, David J.;
Patel, Ketan J.

Publication type:

Article

TranscriptSNPView: a genome-wide catalog of mouse coding variation.

Published in:

Nature Genetics, 2006, v. 38, n. 8, p. 853, doi. 10.1038/ng0806-853a

By:

Cunningham, Fiona;
Rios, Daniel;
Griffiths, Mark;
Smith, James;
Zemin Ning;
Cox, Tony;
Flicek, Paul;
Marin-Garcin, Pablo;
Herrero, Javier;
Rogers, Jane;
van der Weyden, Louise;
Bradley, Allan;
Birney, Ewan;
Adams, David J.

Publication type:

Article

Mutagenic Insertion and Chromosome Engineering Resource (MICER).

Published in:

Nature Genetics, 2004, v. 36, n. 8, p. 867, doi. 10.1038/ng1388

By:

Adams, David J.;
Biggs, Patrick J.;
Cox, Tony;
Davies, Rob;
van der Weyden, Louise;
Jonkers, Jos;
Smith, James;
Plumb, Bob;
Taylor, Ruth;
Nishijima, Ichiko;
Yu, Yuejin;
Rogers, Jane;
Bradley, Allan

Publication type:

Article

Insertional Mutagenesis and Deep Profiling Reveals Gene Hierarchies and a <i>Myc/p53</i>-Dependent Bottleneck in Lymphomagenesis.

Published in:

PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004167

By:

Huser, Camille A.;
Gilroy, Kathryn L.;
de Ridder, Jeroen;
Kilbey, Anna;
Borland, Gillian;
Mackay, Nancy;
Jenkins, Alma;
Bell, Margaret;
Herzyk, Pawel;
van der Weyden, Louise;
Adams, David J.;
Rust, Alistair G.;
Cameron, Ewan;
Neil, James C.

Publication type:

Article

Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome.

Published in:

PLoS Genetics, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.pgen.1003022

By:

McIntyre, Rebecca E.;
Chavali, Pavithra Lakshminarasimhan;
Ismail, Ozama;
Carragher, Damian M.;
Sanchez-Andrade, Gabriela;
Forment, Josep V.;
Beiyuan Fu;
Velasco-Herrera, Martin Del Castillo;
Edwards, Andrew;
van der Weyden, Louise;
Fengtang Yang;
Ramirez-Solis, Ramiro;
Estabel, Jeanne;
Gallagher, Ferdia A.;
Logan, Darren W.;
Arends, Mark J.;
Tsang, Stephen H.;
Mahajan, Vinit B.;
Scudamore, Cheryl L.;
White, Jacqueline K.

Publication type:

Article

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice.

Published in:

2010

By:

Del Re, Dominic P.;
Matsuda, Takahisa;
Peiyong Zhai;
Shumin Gao;
Clark, Geoffrey J.;
Van Der Weyden, Louise;
Sadoshima, Junichi;
Zhai, Peiyong;
Gao, Shumin

Publication type:

journal article

Metastatic urothelial carcinoma of the urinary bladder in a Sumatran tiger (Panthera tigris sondaica).

Published in:

2022

By:

van der Weyden, Louise;
Tibbs, Clare;
Knott, Chris;
Dobromylskyj, Melanie

Publication type:

Case Study

Membrane protein regulators of melanoma pulmonary colonization identified using a CRISPRa screen and spontaneous metastasis assay in mice.

Published in:

G3: Genes | Genomes | Genetics, 2021, v. 11, n. 7, p. 1, doi. 10.1093/g3journal/jkab157

By:

van der Weyden, Louise;
Offord, Victoria;
Turner, Gemma;
Swiatkowska, Agnes;
Speak, Anneliese O.;
Adams, David J.

Publication type:

Article

A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation.

Published in:

G3: Genes | Genomes | Genetics, 2020, v. 10, n. 6, p. 1869, doi. 10.1534/g3.120.401128

By:

van der Weyden, Louise;
Swiatkowska, Agnieszka;
Iyer, Vivek;
Speak, Anneliese O.;
Adams, David J.

Publication type:

Article

Cancer gene discovery goes mobile.

Published in:

Nature Genetics, 2014, v. 46, n. 9, p. 928, doi. 10.1038/ng.3072

By:

van der Weyden, Louise;
Ranzani, Marco;
Adams, David J

Publication type:

Article

CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation.

Published in:

PLoS Pathogens, 2018, v. 14, n. 4, p. 1, doi. 10.1371/journal.ppat.1006968

By:

Hunte, Richard;
Alonso, Patricia;
Thomas, Remy;
Bazile, Cassandra Alexandria;
Ramos, Juan Carlos;
van der Weyden, Louise;
Dominguez-Bendala, Juan;
Khan, Wasif Noor;
Shembade, Noula

Publication type:

Article

Case Report Metastatic Cutaneous Melanoma in a White African Lioness (Panthera leo).

Published in:

Veterinary Sciences, 2021, v. 8, n. 8, p. 1, doi. 10.3390/vetsci8080154

By:

van der Weyden, Louise;
Caldwell, Peter;
van Rooyen, Liesl;
Mitchell, Emily P.;
O'Dell, Nicolize

Publication type:

Article

ZNF265--a novel spliceosomal protein able to induce alternative splicing.

Published in:

Journal of Cell Biology, 2001, v. 154, n. 1, p. 25, doi. 10.1083/jcb.200010059

By:

Adams, David J.;
van der Weyden, Louise;
Mayeda, Akila;
Stamm, Stefan;
Morris, Brian J.;
Rasko, John E.J.

Publication type:

Article

RENIN GENE EXPRESSION: THE SWITCH AND THE FINGERS.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2001, v. 28, n. 12, p. 1044, doi. 10.1046/j.1440-1681.2001.03587.x

By:

Morris, Brian J;
Adams, David J;
Weyden, Louise van der

Publication type:

Article

Pharmacological profile of a novel cyclic AMP-linked P2 receptor on undifferentiated HL-60 leukemia cells.

Published in:

British Journal of Pharmacology, 1998, v. 124, n. 7, p. 1580, doi. 10.1038/sj.bjp.0701985

By:

Conigrave, Arthur D.;
Lee, Joanne Y.;
Van Der Weyden, Louise;
Jiang, Lele;
Ward, Peter;
Tasevski, Vit;
Luttrell, Brian M.;
Morris, Michael B.

Publication type:

Article

A high-throughput in vivo screening method in the mouse for identifying regulators of metastatic colonization.

Published in:

Nature Protocols, 2017, v. 12, n. 12, p. 2465, doi. 10.1038/nprot.2017.118

By:

Speak, Anneliese O;
Swiatkowska, Agnieszka;
Karp, Natasha A;
Arends, Mark J;
Adams, David J;
van der Weyden, Louise

Publication type:

Article

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.

Published in:

Molecular Cancer, 2012, v. 11, n. 1, p. 29, doi. 10.1186/1476-4598-11-29

By:

van der Weyden, Louise;
Arends, Mark J.;
Rust, Alistair G.;
Poulogiannis, George;
McIntyre, Rebecca E.;
Adams, David J.

Publication type:

Article

Megaoesophagus in Rassf1a-null mice.

Published in:

International Journal of Experimental Pathology, 2009, v. 90, n. 2, p. 101, doi. 10.1111/j.1365-2613.2008.00635.x

By:

van der Weyden, Louise;
Happerfield, Lisa;
Arends, Mark J.;
Adams, David J.

Publication type:

Article

Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-κB Inhibitor A20 and Constitutive NF-κB Signaling.

Published in:

PLoS Pathogens, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.ppat.1004721

By:

Pujari, Rajeshree;
Hunte, Richard;
Thomas, Remy;
van der Weyden, Louise;
Rauch, Dan;
Ratner, Lee;
Nyborg, Jennifer K.;
Ramos, Juan Carlos;
Takai, Yoshimi;
Shembade, Noula

Publication type:

Article

FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0212481

By:

Ballesteros Reviriego, Carmen;
Clare, Simon;
Arends, Mark J.;
Cambridge, Emma L.;
Swiatkowska, Agnieszka;
Caetano, Susana;
Abu-Helil, Bushra;
Kane, Leanne;
Harcourt, Katherine;
Goulding, David A.;
Gleeson, Diane;
Ryder, Edward;
Doe, Brendan;
White, Jacqueline K.;
van der Weyden, Louise;
Dougan, Gordon;
Adams, David J.;
Speak, Anneliese O.

Publication type:

Article

Exploration of the mutational landscape of cutaneous leiomyoma confirms FH as a driver gene and identifies targeting purine metabolism as a potential therapeutic strategy.

Published in:

British Journal of Dermatology, 2025, v. 192, n. 3, p. 551, doi. 10.1093/bjd/ljae432

By:

van der Weyden, Louise;
Velasco-Herrera, Martin Del Castillo;
Cheema, Saamin;
Wong, Kim;
Boccacino, Jacqueline M;
Vermes, Ian;
Offord, Victoria;
Droop, Alastair;
Jones, David R A;
Anderson, Elizabeth;
Hardy, Claire;
Aubain, Nicolas de Saint;
Ferguson, Peter M;
Mogler, Carolin;
Rajan, Neil;
Frew, Derek;
Harms, Paul W;
Billings, Steven D;
Schatton, Désirée;
Segarra-Mondejar, Marc

Publication type:

Article

Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma.

Published in:

British Journal of Dermatology, 2025, v. 192, p. 335, doi. 10.1093/bjd/ljae386

By:

van der Weyden, Louise;
Velasco-Herrera, Martin Del Castillo;
Cheema, Saamin;
Wong, Kim;
Boccacino, Jacqueline M;
Offord, Victoria;
Droop, Alastair;
Jones, David R A;
Vermes, Ian;
Anderson, Elizabeth;
Hardy, Claire;
Aubain, Nicolas de Saint;
Ferguson, Peter M;
Clarke, Emily L;
Merchant, William;
Mogler, Carolin;
Frew, Derek;
Harms, Paul W;
Monteagudo, Carlos;
Billings, Steven D

Publication type:

Article

Review of Molecular Technologies for Investigating Canine Cancer.

Published in:

Animals (2076-2615), 2024, v. 14, n. 5, p. 769, doi. 10.3390/ani14050769

By:

Kehl, Alexandra;
Aupperle-Lellbach, Heike;
de Brot, Simone;
van der Weyden, Louise

Publication type:

Article

Artificial Intelligence to Predict the BRAF V595E Mutation in Canine Urinary Bladder Urothelial Carcinomas.

Published in:

Animals (2076-2615), 2023, v. 13, n. 15, p. 2404, doi. 10.3390/ani13152404

By:

Küchler, Leonore;
Posthaus, Caroline;
Jäger, Kathrin;
Guscetti, Franco;
van der Weyden, Louise;
von Bomhard, Wolf;
Schmidt, Jarno M.;
Farra, Dima;
Aupperle-Lellbach, Heike;
Kehl, Alexandra;
Rottenberg, Sven;
de Brot, Simone

Publication type:

Article

Sequencing and characterization of the FVB/NJ mouse genome.

Published in:

Genome Biology, 2012, v. 13, n. 8, p. 1, doi. 10.1186/gb-2012-13-8-r72

By:

Kim Wong;
Bumpstead, Suzannah;
Der Weyden, Louise Van;
Reinholdt, Laura G.;
Wilming, Laurens G.;
Adams, David J.;
Keane, Thomas M.

Publication type:

Article

The mouse genetics toolkit: revealing function and mechanism.

Published in:

Genome Biology, 2011, v. 12, n. 6, p. 224, doi. 10.1186/gb-2011-12-6-224

By:

van der Weyden, Louise;
White, Jacqueline K.;
Adams, David J.;
Logan, Darren W.

Publication type:

Article

Successful treatment of early cutaneous squamous cell carcinoma with hypofractionated radiation therapy in an African lion (Panthera leo).

Published in:

2021

By:

van der Weyden, Louise;
O'Dell, Nicolize;
Avenant, Alida;
Pazzi, Paolo;
Koeppel, Katja N.

Publication type:

Case Study

Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.

Published in:

EMBO Journal, 2012, v. 31, n. 11, p. 2486, doi. 10.1038/emboj.2012.91

By:

Wilson, Catherine H;
Crombie, Catriona;
van der Weyden, Louise;
Poulogiannis, George;
Rust, Alistair G;
Pardo, Mercedes;
Gracia, Tannia;
Yu, Lu;
Choudhary, Jyoti;
Poulin, Gino B;
McIntyre, Rebecca E;
Winton, Douglas J;
March, H Nikki;
Arends, Mark J;
Fraser, Andrew G;
Adams, David J

Publication type:

Article

Null and conditional semaphorin 3B alleles using a flexible puroΔtk loxP/FRT vector.

Published in:

Genesis: The Journal of Genetics & Development, 2005, v. 41, n. 4, p. 171, doi. 10.1002/gene.20111

By:

Louise van der Weyden;
David J. Adams;
Laura W. Harris;
David Tannahill;
Mark J. Arends;
Allan Bradley

Publication type:

Article

Are we Creating problems? Negative effects of Cre recombinase.

Published in:

Genesis: The Journal of Genetics & Development, 2001, v. 29, n. 3, p. 115, doi. 10.1002/gene.1012

By:

Adams, David J.;
van der Weyden, Louise

Publication type:

Article

Stuck at first base.

Published in:

Nature, 2002, v. 419, n. 6903, p. 127, doi. 10.1038/419127a

By:

van der Weyden, Louise;
Jonkers, Jos;
Bradley, Allan

Publication type:

Article

Shared immunohistochemical and genomic features of the low‐ and high‐grade components of a cutaneous secretory carcinoma with epidermotrophism and lymph node involvement.

Published in:

Histopathology, 2025, v. 86, n. 4, p. 656, doi. 10.1111/his.15351

By:

Marusic, Zlatko;
van der Weyden, Louise;
Suárez Vilela, Dimas;
Suárez Sánchez, Faustino;
Méndez Álvarez, Jose Ramón;
Velasco‐Herrera, Martin Del Castillo;
Ferreira, Ingrid;
Adams, David J;
Calonje, Eduardo

Publication type:

Article

Primary de‐differentiated, trans‐differentiated and undifferentiated melanomas: overview of the clinicopathological, immunohistochemical and molecular spectrum.

Published in:

Histopathology, 2022, v. 80, n. 1, p. 135, doi. 10.1111/his.14545

By:

Ferreira, Ingrid;
Arends, Mark J;
van der Weyden, Louise;
Adams, David J;
Brenn, Thomas

Publication type:

Article

Erratum: RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.

Published in:

Nature Cell Biology, 2015, v. 17, n. 4, p. 531, doi. 10.1038/ncb3152

By:

Pefani, Dafni-Eleftheria;
Latusek, Robert;
Pires, Isabel;
Grawenda, Anna M.;
Yee, Karen S.;
Hamilton, Garth;
van der Weyden, Louise;
Esashi, Fumiko;
Hammond, Ester M.;
O'Neill, Eric

Publication type:

Article

RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.

Published in:

Nature Cell Biology, 2014, v. 16, n. 10, p. 962, doi. 10.1038/ncb3035

By:

Pefani, Dafni-Eleftheria;
Latusek, Robert;
Pires, Isabel;
Grawenda, Anna M.;
Yee, Karen S.;
Hamilton, Garth;
van der Weyden, Louise;
Esashi, Fumiko;
Hammond, Ester M.;
O'Neill, Eric

Publication type:

Article