Works by Westpheling, Janet

Results: 36

Engineering the N-terminal end of CelA results in improved performance and growth of Caldicellulosiruptor bescii on crystalline cellulose.

Published in:

Biotechnology & Bioengineering, 2017, v. 114, n. 5, p. 945, doi. 10.1002/bit.26242

By:

Kim, Sun‐Ki;
Chung, Daehwan;
Himmel, Michael E.;
Bomble, Yannick J.;
Westpheling, Janet

Publication type:

Article

Deletion of a gene cluster for [Ni-Fe] hydrogenase maturation in the anaerobic hyperthermophilic bacterium Caldicellulosiruptor bescii identifies its role in hydrogen metabolism.

Published in:

Applied Microbiology & Biotechnology, 2016, v. 100, n. 4, p. 1823, doi. 10.1007/s00253-015-7025-z

By:

Cha, Minseok;
Chung, Daehwan;
Westpheling, Janet

Publication type:

Article

Rational development of transformation in Clostridium thermocellum ATCC 27405 via complete methylome analysis and evasion of native restriction–modification systems.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 9/10, p. 1435, doi. 10.1007/s10295-019-02218-x

By:

Riley, Lauren A.;
Ji, Lexiang;
Schmitz, Robert J.;
Westpheling, Janet;
Guss, Adam M.

Publication type:

Article

Heterologous co-expression of two β-glucanases and a cellobiose phosphorylase resulted in a significant increase in the cellulolytic activity of the Caldicellulosiruptor bescii exoproteome.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 5, p. 687, doi. 10.1007/s10295-019-02150-0

By:

Kim, Sun-Ki;
Chung, Daehwan;
Himmel, Michael E.;
Bomble, Yannick J.;
Westpheling, Janet

Publication type:

Article

Deletion of the Clostridium thermocellum recA gene reveals that it is required for thermophilic plasmid replication but not plasmid integration at homologous DNA sequences.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2018, v. 45, n. 8, p. 753, doi. 10.1007/s10295-018-2049-x

By:

Groom, Joseph;
Chung, Daehwan;
Kim, Sun-Ki;
Guss, Adam;
Westpheling, Janet

Publication type:

Article

Heterologous expression of a β- d-glucosidase in Caldicellulosiruptor bescii has a surprisingly modest effect on the activity of the exoproteome and growth on crystalline cellulose.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2017, v. 44, n. 12, p. 1643, doi. 10.1007/s10295-017-1982-4

By:

Kim, Sun-Ki;
Chung, Daehwan;
Himmel, Michael;
Bomble, Yannick;
Westpheling, Janet

Publication type:

Article

Isolation and bioinformatic analysis of a novel transposable element, ISCbe4, from the hyperthermophilic bacterium, Caldicellulosiruptor bescii.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 12, p. 1443, doi. 10.1007/s10295-013-1345-8

By:

Cha, Minseok;
Wang, Hao;
Chung, Daehwan;
Bennetzen, Jeffrey L.;
Westpheling, Janet

Publication type:

Article

Detection of a novel active transposable element in Caldicellulosiruptor hydrothermalis and a new search for elements in this genus.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 5, p. 517, doi. 10.1007/s10295-013-1244-z

By:

Chung, Daehwan;
Farkas, Joel;
Westpheling, Janet

Publication type:

Article

Improved growth media and culture techniques for genetic analysis and assessment of biomass utilization by Caldicellulosiruptor bescii.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 1, p. 41, doi. 10.1007/s10295-012-1202-1

By:

Farkas, Joel;
Chung, Daehwan;
Cha, Minseok;
Copeland, Jennifer;
Grayeski, Philip;
Westpheling, Janet

Publication type:

Article

Identification and characterization of CbeI, a novel thermostable restriction enzyme from Caldicellulosiruptor bescii DSM 6725 and a member of a new subfamily of HaeIII-like enzymes.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2011, v. 38, n. 11, p. 1867, doi. 10.1007/s10295-011-0976-x

By:

Chung, Dae-Hwan;
Huddleston, Jennifer;
Farkas, Joel;
Westpheling, Janet

Publication type:

Article

Branched-chain amino acid catabolism provides precursors for the Type II polyketide antibiotic, actinorhodin, via pathways that are nutrient dependent.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2009, v. 36, n. 1, p. 129, doi. 10.1007/s10295-008-0480-0

By:

Stirrett, Karen;
Denoya, Claudio;
Westpheling, Janet

Publication type:

Article

In vivo synergistic activity of a CAZyme cassette from Acidothermus cellulolyticus significantly improves the cellulolytic activity of the C. bescii exoproteome.

Published in:

Biotechnology & Bioengineering, 2017, v. 114, n. 11, p. 2474, doi. 10.1002/bit.26366

By:

Kim, Sun‐Ki;
Chung, Daehwan;
Himmel, Michael E.;
Bomble, Yannick J.;
Westpheling, Janet

Publication type:

Article

Structure and function of the Bacillus SpollE protein and its localization to sites of sporulation septum assembly.

Published in:

Molecular Microbiology, 1996, v. 19, n. 5, p. 1047, doi. 10.1046/j.1365-2958.1996.433963.x

By:

Barák, Imrich;
Behari, Jaideep;
Olmedo, Gabriela;
Guzmán, Plinio;
Brown, David P.;
Castro, Elda;
Walker, DeEtte;
Westpheling, Janet;
Youngman, Philip

Publication type:

Article

The bid mutants of Streptomyces coelicolor are defective in the regulation of carbon utilization, morphogenesis and cell-cell signalling.

Published in:

Molecular Microbiology, 1996, v. 19, n. 4, p. 747, doi. 10.1046/j.1365-2958.1996.414933.x

By:

Pop, Margaret K.;
Green, Brian D.;
Westpheling, Janet

Publication type:

Article

Insights into plant biomass conversion from the genome of the anaerobic thermophilic bacterium Caldicellulosiruptor bescii DSM 6725.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 8, p. 3240, doi. 10.1093/nar/gkq1281

By:

Dam, Phuongan;
Kataeva, Irina;
Yang, Sung-Jae;
Zhou, Fengfeng;
Yin, Yanbin;
Chou, Wenchi;
Poole, Farris L.;
Westpheling, Janet;
Hettich, Robert;
Giannone, Richard;
Lewis, Derrick L.;
Kelly, Robert;
Gilbert, Harry J.;
Henrissat, Bernard;
Xu, Ying;
Adams, Michael W. W.

Publication type:

Article

Gene targets for engineering osmotolerance in Caldicellulosiruptor bescii.

Published in:

Biotechnology for Biofuels, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13068-020-01690-3

By:

Sander, Kyle B.;
Chung, Daehwan;
Klingeman, Dawn M.;
Giannone, Richard J.;
Rodriguez, Miguel;
Whitham, Jason;
Hettich, Robert L.;
Davison, Brian H.;
Westpheling, Janet;
Brown, Steven D.

Publication type:

Article

Characterization of the Biomass Degrading Enzyme GuxA from Acidothermus cellulolyticus.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 6070, doi. 10.3390/ijms23116070

By:

Hengge, Neal N.;
Mallinson, Sam J. B.;
Pason, Patthra;
Lunin, Vladimir V.;
Alahuhta, Markus;
Chung, Daehwan;
Himmel, Michael E.;
Westpheling, Janet;
Bomble, Yannick J.

Publication type:

Article

Rex in Caldicellulosiruptor bescii: Novel regulon members and its effect on the production of ethanol and overflow metabolites.

Published in:

MicrobiologyOpen, 2019, v. 8, n. 2, p. N.PAG, doi. 10.1002/mbo3.639

By:

Sander, Kyle;
Chung, Daehwan;
Hyatt, Doug;
Westpheling, Janet;
Klingeman, Dawn M.;
Rodriguez, Miguel;
Engle, Nancy L.;
Tschaplinski, Timothy J.;
Davison, Brian H.;
Brown, Steven D.

Publication type:

Article

Simultaneous expression of an endogenous spermidine synthase and a butanol dehydrogenase from Thermoanaerobacter pseudethanolicus in Clostridium thermocellum results in increased resistance to acetic acid and furans, increased ethanol production and an increase in thermotolerance

Published in:

Biotechnology for Biofuels & Bioproducts, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13068-023-02291-6

By:

Kim, Sun-Ki;
Bomble, Yannick J.;
Westpheling, Janet

Publication type:

Article

Expression of a heat-stable NADPH-dependent alcohol dehydrogenase from Thermoanaerobacter pseudethanolicus 39E in Clostridium thermocellum 1313 results in increased hydroxymethylfurfural resistance.

Published in:

Biotechnology for Biofuels, 2017, v. 10, p. 1, doi. 10.1186/s13068-017-0750-z

By:

Sun-Ki Kim;
Groom, Joseph;
Daehwan Chung;
Elkins, James;
Westpheling, Janet

Publication type:

Article

Heterologous expression of family 10 xylanases from Acidothermus cellulolyticus enhances the exoproteome of Caldicellulosiruptor bescii and growth on xylan substrates.

Published in:

Biotechnology for Biofuels, 2016, v. 9, p. 1, doi. 10.1186/s13068-016-0588-9

By:

Sun-Ki Kim;
Daehwan Chung;
Himmel, Michael E.;
Bomble, Yannick J.;
Westpheling, Janet

Publication type:

Article

Cellulosic ethanol production via consolidated bioprocessing at 75 °C by engineered Caldicellulosiruptor bescii.

Published in:

Biotechnology for Biofuels, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13068-015-0346-4

By:

Chung, Daehwan;
Cha, Minseok;
Snyder, Elise N.;
Elkins, James G.;
Guss, Adam M.;
Westpheling, Janet

Publication type:

Article

Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite-sequencing.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 21, p. 1, doi. 10.1093/nar/gkv738

By:

Miao Yu;
Lexiang Ji;
Neumann, Drexel A.;
Dae-hwan Chung;
Groom, Joseph;
Westpheling, Janet;
Chuan He;
Schmitz, Robert J.

Publication type:

Article

Expression of the Acidothermus cellulolyticus E1 endoglucanase in Caldicellulosiruptor bescii enhances its ability to deconstruct crystalline cellulose.

Published in:

Biotechnology for Biofuels, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13068-015-0296-x

By:

Daehwan Chung;
Jenna Young;
Minseok Cha;
Brunecky, Roman;
Bomble, Yannick J.;
Himmel, Michael E.;
Westpheling, Janet

Publication type:

Article

Expression of a heat-stable NADPH-dependent alcohol dehydrogenase in Caldicellulosiruptor bescii results in furan aldehyde detoxification.

Published in:

Biotechnology for Biofuels, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13068-015-0287-y

By:

Chung, Daehwan;
Verbeke, Tobin J.;
Cross, Karissa L.;
Westpheling, Janet;
Elkins, James G.

Publication type:

Article

Deletion of a gene cluster encoding pectin degrading enzymes in Caldicellulosiruptor bescii reveals an important role for pectin in plant biomass recalcitrance.

Published in:

Biotechnology for Biofuels, 2014, v. 7, n. 1, p. 1, doi. 10.1186/s13068-014-0147-1

By:

Daehwan Chung;
Pattathil, Sivakumar;
Biswal, Ajaya K.;
Hahn, Michael G.;
Mohnen, Debra;
Westpheling, Janet

Publication type:

Article

Deletion of Caldicellulosiruptor bescii CelA reveals its crucial role in the deconstruction of lignocellulosic biomass.

Published in:

Biotechnology for Biofuels, 2014, v. 7, n. 1, p. 1, doi. 10.1186/s13068-014-0142-6

By:

Young, Jenna;
Daehwan Chung;
Bomble, Yannick J.;
Himmel, Michael E.;
Westpheling, Janet

Publication type:

Article

Heterologous complementation of a pyrF deletion in Caldicellulosiruptor hydrothermalis generates a new host for the analysis of biomass deconstruction.

Published in:

Biotechnology for Biofuels, 2014, v. 7, n. 1, p. 1, doi. 10.1186/s13068-014-0132-8

By:

Groom, Joseph;
Chung, Daehwan;
Young, Jenna;
Westpheling, Janet

Publication type:

Article

Metabolic engineering of Caldicellulosiruptor bescii yields increased hydrogen production from lignocellulosic biomass.

Published in:

Biotechnology for Biofuels, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1754-6834-6-85

By:

Minseok Cha;
Daehwan Chung;
Elkins, James G.;
Guss, Adam M.;
Westpheling, Janet

Publication type:

Article

Overcoming restriction as a barrier to DNA transformation in Caldicellulosiruptor species results in efficient marker replacement.

Published in:

Biotechnology for Biofuels, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1754-6834-6-82

By:

Daehwan Chung;
Farkas, Joel;
Westpheling, Janet

Publication type:

Article

Homologous Expression of the Caldicellulosiruptor bescii CelA Reveals that the Extracellular Protein Is Glycosylated.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119508

By:

Chung, Daehwan;
Young, Jenna;
Bomble, Yannick J.;
Vander Wall, Todd A.;
Groom, Joseph;
Himmel, Michael E.;
Westpheling, Janet

Publication type:

Article

Construction of a Stable Replicating Shuttle Vector for Caldicellulosiruptor Species: Use for Extending Genetic Methodologies to Other Members of This Genus

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062881

By:

Chung, Daehwan;
Cha, Minseok;
Farkas, Joel;
Westpheling, Janet

Publication type:

Article

Methylation by a Unique α-class N4-Cytosine Methyltransferase Is Required for DNA Transformation of Caldicellulosiruptor bescii DSM6725.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043844

By:

Daehwan Chung;
Farkas, Joel;
Huddleston, Jennifer R.;
Olivar, Estefania;
Westpheling, Janet;
Freitag, Michael

Publication type:

Article

Deletion of a single glycosyltransferase in Caldicellulosiruptor bescii eliminates protein glycosylation and growth on crystalline cellulose.

Published in:

Biotechnology for Biofuels, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13068-018-1266-x

By:

Russell, Jordan;
Duma, Justin;
Szymanski, Christine M.;
Westpheling, Janet;
Kim, Sun-Ki;
Nothaft, Harald;
Himmel, Michael E.;
Bomble, Yannick J.

Publication type:

Article

High activity CAZyme cassette for improving biomass degradation in thermophiles.

Published in:

Biotechnology for Biofuels, 2018, v. 11, p. 1, doi. 10.1186/s13068-018-1014-2

By:

Brunecky, Roman;
Chung, Daehwan;
Sarai, Nicholas S.;
Hengge, Neal;
Russell, Jordan F.;
Young, Jenna;
Mittal, Ashutosh;
Pason, Patthra;
Vander Wall, Todd;
Michener, William;
Shollenberger, Todd;
Westpheling, Janet;
Himmel, Michael E.;
Bomble, Yannick J.

Publication type:

Article

An integrative expression vector for Actinosynnema pretiosum.

Published in:

BMC Biotechnology, 2007, v. 7, p. 72, doi. 10.1186/1472-6750-7-72

By:

Shan Goh;
Camattari, Andrea;
Ng, Daniel;
Song, Ruth;
Madden, Kevin;
Westpheling, Janet;
Wong, Victor V.T.

Publication type:

Article

Works by Westpheling, Janet

Engineering the N-terminal end of CelA results in improved performance and growth of Caldicellulosiruptor bescii on crystalline cellulose.

Deletion of a gene cluster for [Ni-Fe] hydrogenase maturation in the anaerobic hyperthermophilic bacterium Caldicellulosiruptor bescii identifies its role in hydrogen metabolism.

Rational development of transformation in Clostridium thermocellum ATCC 27405 via complete methylome analysis and evasion of native restriction–modification systems.

Heterologous co-expression of two β-glucanases and a cellobiose phosphorylase resulted in a significant increase in the cellulolytic activity of the Caldicellulosiruptor bescii exoproteome.

Deletion of the Clostridium thermocellum recA gene reveals that it is required for thermophilic plasmid replication but not plasmid integration at homologous DNA sequences.

Heterologous expression of a β- d-glucosidase in Caldicellulosiruptor bescii has a surprisingly modest effect on the activity of the exoproteome and growth on crystalline cellulose.

Isolation and bioinformatic analysis of a novel transposable element, IS<i>Cbe</i>4, from the hyperthermophilic bacterium, <i>Caldicellulosiruptor bescii</i>.

Detection of a novel active transposable element in Caldicellulosiruptor hydrothermalis and a new search for elements in this genus.

Improved growth media and culture techniques for genetic analysis and assessment of biomass utilization by Caldicellulosiruptor bescii.

Identification and characterization of CbeI, a novel thermostable restriction enzyme from Caldicellulosiruptor bescii DSM 6725 and a member of a new subfamily of HaeIII-like enzymes.

Branched-chain amino acid catabolism provides precursors for the Type II polyketide antibiotic, actinorhodin, via pathways that are nutrient dependent.

In vivo synergistic activity of a CAZyme cassette from Acidothermus cellulolyticus significantly improves the cellulolytic activity of the C. bescii exoproteome.

Structure and function of the Bacillus SpollE protein and its localization to sites of sporulation septum assembly.

The bid mutants of Streptomyces coelicolor are defective in the regulation of carbon utilization, morphogenesis and cell-cell signalling.

Insights into plant biomass conversion from the genome of the anaerobic thermophilic bacterium Caldicellulosiruptor bescii DSM 6725.

Gene targets for engineering osmotolerance in Caldicellulosiruptor bescii.

Characterization of the Biomass Degrading Enzyme GuxA from Acidothermus cellulolyticus.

Rex in Caldicellulosiruptor bescii: Novel regulon members and its effect on the production of ethanol and overflow metabolites.

Simultaneous expression of an endogenous spermidine synthase and a butanol dehydrogenase from Thermoanaerobacter pseudethanolicus in Clostridium thermocellum results in increased resistance to acetic acid and furans, increased ethanol production and an increase in thermotolerance

Expression of a heat-stable NADPH-dependent alcohol dehydrogenase from Thermoanaerobacter pseudethanolicus 39E in Clostridium thermocellum 1313 results in increased hydroxymethylfurfural resistance.

Heterologous expression of family 10 xylanases from Acidothermus cellulolyticus enhances the exoproteome of Caldicellulosiruptor bescii and growth on xylan substrates.

Cellulosic ethanol production via consolidated bioprocessing at 75 °C by engineered Caldicellulosiruptor bescii.

Base-resolution detection of N<sup>4</sup>-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite-sequencing.

Expression of the Acidothermus cellulolyticus E1 endoglucanase in Caldicellulosiruptor bescii enhances its ability to deconstruct crystalline cellulose.

Expression of a heat-stable NADPH-dependent alcohol dehydrogenase in Caldicellulosiruptor bescii results in furan aldehyde detoxification.

Deletion of a gene cluster encoding pectin degrading enzymes in Caldicellulosiruptor bescii reveals an important role for pectin in plant biomass recalcitrance.

Deletion of Caldicellulosiruptor bescii CelA reveals its crucial role in the deconstruction of lignocellulosic biomass.

Heterologous complementation of a pyrF deletion in Caldicellulosiruptor hydrothermalis generates a new host for the analysis of biomass deconstruction.

Metabolic engineering of Caldicellulosiruptor bescii yields increased hydrogen production from lignocellulosic biomass.

Overcoming restriction as a barrier to DNA transformation in Caldicellulosiruptor species results in efficient marker replacement.

Homologous Expression of the Caldicellulosiruptor bescii CelA Reveals that the Extracellular Protein Is Glycosylated.

Construction of a Stable Replicating Shuttle Vector for <i>Caldicellulosiruptor</i> Species: Use for Extending Genetic Methodologies to Other Members of This Genus

Methylation by a Unique α-class N4-Cytosine Methyltransferase Is Required for DNA Transformation of Caldicellulosiruptor bescii DSM6725.

Deletion of a single glycosyltransferase in Caldicellulosiruptor bescii eliminates protein glycosylation and growth on crystalline cellulose.

High activity CAZyme cassette for improving biomass degradation in thermophiles.

An integrative expression vector for Actinosynnema pretiosum.