Works by Werz, Oliver

Results: 142

Anti-Influenza Activity of 6BIGOE: Improved Pharmacological Profile After Encapsulation in PLGA Nanoparticles.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4235, doi. 10.3390/ijms26094235

By:

Schroeder, Josefine;
Westhoff, Jan;
Vilotijević, Ivan;
Werz, Oliver;
Hoeppener, Stephanie;
Löffler, Bettina;
Fischer, Dagmar;
Ehrhardt, Christina

Publication type:

Article

2‐Phenylbenzothiazoles featuring heteroaryl sulfonamide end‐capping substructures as developable mPGES‐1 inhibitors.

Published in:

Archiv der Pharmazie, 2025, v. 358, n. 1, p. 1, doi. 10.1002/ardp.202400756

By:

Yalçın, Tansu;
Jordan, Paul M.;
Olğaç, Abdurrahman;
Dahlke, Philipp;
Maz, Tuğçe Gür;
Banoglu, Erden;
Werz, Oliver;
Çalışkan, Burcu

Publication type:

Article

5‐methyl‐2‐carboxamidepyrrole‐based novel dual mPGES‐1/sEH inhibitors as promising anticancer candidates.

Published in:

Archiv der Pharmazie, 2025, v. 358, n. 1, p. 1, doi. 10.1002/ardp.202400708

By:

Colarusso, Ester;
Lauro, Gianluigi;
Potenza, Marianna;
Galatello, Paola;
Garigliota, Maria Luisa d'Aulisio;
Ferraro, Maria Grazia;
Piccolo, Marialuisa;
Chini, Maria Giovanna;
Irace, Carlo;
Campiglia, Pietro;
Hoffstetter, Robert Klaus;
Werz, Oliver;
Ramunno, Anna;
Bifulco, Giuseppe

Publication type:

Article

Totalsynthese von Myrtucommulon A.

Published in:

Angewandte Chemie, 2010, v. 122, n. 11, p. 2089, doi. 10.1002/ange.200903906

By:

Müller, Hans;
Paul, Michael;
Hartmann, David;
Huch, Volker;
Blaesius, Dagmar;
Koeberle, Andreas;
Werz, Oliver;
Jauch, Johann

Publication type:

Article

Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.

Published in:

Aging Cell, 2023, v. 22, n. 7, p. 1, doi. 10.1111/acel.13856

By:

Schädel, Patrick;
Czapka, Anna;
Gebert, Nadja;
Jacobsen, Ilse Denise;
Ori, Alessandro;
Werz, Oliver

Publication type:

Article

Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation.

Published in:

Advanced Science, 2023, v. 10, n. 6, p. 1, doi. 10.1002/advs.202205604

By:

Börner, Friedemann;
Pace, Simona;
Jordan, Paul M.;
Gerstmeier, Jana;
Gomez, Mario;
Rossi, Antonietta;
Gilbert, Nathaniel C.;
Newcomer, Marcia E.;
Werz, Oliver

Publication type:

Article

Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase‐1 Inhibitors by Automated De Novo Design.

Published in:

Advanced Science, 2021, v. 8, n. 16, p. 1, doi. 10.1002/advs.202100832

By:

Friedrich, Lukas;
Cingolani, Gino;
Ko, Ying‐Hui;
Iaselli, Mariaclara;
Miciaccia, Morena;
Perrone, Maria Grazia;
Neukirch, Konstantin;
Bobinger, Veronika;
Merk, Daniel;
Hofstetter, Robert Klaus;
Werz, Oliver;
Koeberle, Andreas;
Scilimati, Antonio;
Schneider, Gisbert

Publication type:

Article

Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase‐1 Inhibitors by Automated De Novo Design.

Published in:

Advanced Science, 2021, v. 8, n. 16, p. 1, doi. 10.1002/advs.202100832

By:

Friedrich, Lukas;
Cingolani, Gino;
Ko, Ying‐Hui;
Iaselli, Mariaclara;
Miciaccia, Morena;
Perrone, Maria Grazia;
Neukirch, Konstantin;
Bobinger, Veronika;
Merk, Daniel;
Hofstetter, Robert Klaus;
Werz, Oliver;
Koeberle, Andreas;
Scilimati, Antonio;
Schneider, Gisbert

Publication type:

Article

Anti-Inflammatory Activities of Arnica montana Planta Tota versus Flower Extracts: Analytical, In Vitro and In Vivo Mouse Paw Oedema Model Studies.

Published in:

Plants (2223-7747), 2023, v. 12, n. 6, p. 1348, doi. 10.3390/plants12061348

By:

Röhrl, Johann;
Piqué-Borràs, Maria-Riera;
Jaklin, Manuela;
Werner, Markus;
Werz, Oliver;
Josef, Heinke;
Hölz, Hubert;
Ammendola, Aldo;
Künstle, Gerald

Publication type:

Article

Frankincense preparation promotes formation of inflammation-resolving lipid mediators by manipulating lipoxygenases in human innate immune cells.

Published in:

Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2023.1332628

By:

Nischang, Vivien;
Witt, Finja M.;
Börner, Friedemann;
Gomez, Mario;
Jordan, Paul M.;
Werz, Oliver

Publication type:

Article

Editorial: Lipidomics of oxylipins in biological systems.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1342596

By:

Patrignani, Paola;
Schebb, Nils Helge;
Werz, Oliver;
Steinhilber, Dieter

Publication type:

Article

Differential impact of 5-lipoxygenase-activating protein antagonists on the biosynthesis of leukotrienes and of specialized pro-resolving mediators.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1219160

By:

Dahlke, Philipp;
Peltner, Lukas K.;
Jordan, Paul M.;
Werz, Oliver

Publication type:

Article

Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.937466

By:

Garcia-Moreno, Marina;
Jordan, Paul M.;
Günther, Kerstin;
Dau, Therese;
Fritzsch, Christian;
Vermes, Monika;
Schoppa, Astrid;
Ignatius, Anita;
Wildemann, Britt;
Werz, Oliver;
Löffler, Bettina;
Tuchscherr, Lorena

Publication type:

Article

Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46037-w

By:

Sharifi, Samim;
Chaudhari, Prerana;
Martirosyan, Asya;
Eberhardt, Alexander Otto;
Witt, Finja;
Gollowitzer, André;
Lange, Lisa;
Woitzat, Yvonne;
Okoli, Eberechukwu Maryann;
Li, Huahui;
Rahnis, Norman;
Kirkpatrick, Joanna;
Werz, Oliver;
Ori, Alessandro;
Koeberle, Andreas;
Bierhoff, Holger;
Ermolaeva, Maria

Publication type:

Article

Author Correction: Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity.

Published in:

2023

By:

Werz, Oliver;
Gerstmeier, Jana;
Libreros, Stephania;
De la Rosa, Xavier;
Werner, Markus;
Norris, Paul C.;
Chiang, Nan;
Serhan, Charles N.

Publication type:

Correction Notice

The Fatal Mushroom Neurotoxin Muscarine is Released from a Harmless Phosphorylated Precursor upon Cellular Injury.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 52, p. 1, doi. 10.1002/anie.202417220

By:

Dörner, Sebastian;
Trottmann, Felix;
Jordan, Paul M.;
Rogge, Kai;
Bartels, Benjamin;
Werz, Oliver;
Hertweck, Christian;
Hoffmeister, Dirk

Publication type:

Article

Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 23, p. 1, doi. 10.1002/anie.202401195

By:

Roman, Dávid;
Meisinger, Philippe;
Guillonneau, Richard;
Peng, Chia‐Chi;
Peltner, Lukas K.;
Jordan, Paul M.;
Haensch, Veit;
Götze, Sebastian;
Werz, Oliver;
Hertweck, Christian;
Chen, Yin;
Beemelmanns, Christine

Publication type:

Article

15‐Hydroperoxy‐PGE<sub>2</sub>: Intermediate in Mammalian and Algal Prostaglandin Biosynthesis.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 49, p. 17641, doi. 10.1002/anie.201910461

By:

Jagusch, Hans;
Werner, Markus;
Werz, Oliver;
Pohnert, Georg

Publication type:

Article

Structure-Function Relationship Studies In Vitro Reveal Distinct and Specific Effects of Long-Chain Metabolites of Vitamin E.

Published in:

Molecular Nutrition & Food Research, 2017, v. 61, n. 12, p. n/a, doi. 10.1002/mnfr.201700562

By:

Schmölz, Lisa;
Wallert, Maria;
Rozzino, Nicolò;
Cignarella, Andrea;
Galli, Francesco;
Glei, Michael;
Werz, Oliver;
Koeberle, Andreas;
Birringer, Marc;
Lorkowski, Stefan

Publication type:

Article

α-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages.

Published in:

Molecular Nutrition & Food Research, 2015, v. 59, n. 8, p. 1524, doi. 10.1002/mnfr.201400737

By:

Wallert, Maria;
Schmölz, Lisa;
Koeberle, Andreas;
Krauth, Verena;
Glei, Michael;
Galli, Francesco;
Werz, Oliver;
Birringer, Marc;
Lorkowski, Stefan

Publication type:

Article

Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.

Published in:

British Journal of Cancer, 2018, v. 118, n. 1, p. 43, doi. 10.1038/bjc.2017.374

By:

Stoiber, Katharina;
Nagło, Olga;
Pernpeintner, Carla;
Zhang, Siwei;
Koeberle, Andreas;
Ulrich, Melanie;
Werz, Oliver;
Müller, Rolf;
Zahler, Stefan;
Lohmüller, Theobald;
Feldmann, Jochen;
Braig, Simone

Publication type:

Article

Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.

Published in:

2017

By:

Stoiber, Katharina;
Nagło, Olga;
Pernpeintner, Carla;
Zhang, Siwei;
Koeberle, Andreas;
Ulrich, Melanie;
Werz, Oliver;
Müller, Rolf;
Zahler, Stefan;
Lohmüller, Theobald;
Feldmann, Jochen;
Braig, Simone

Publication type:

journal article

Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?

Published in:

Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-023-02981-w

By:

Broos, Jelle Y.;
van der Burgt, Rianne T. M.;
Konings, Julia;
Rijnsburger, Merel;
Werz, Oliver;
de Vries, Helga E.;
Giera, Martin;
Kooij, Gijs

Publication type:

Article

Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3866, doi. 10.3390/molecules27123866

By:

Gazzillo, Erica;
Terracciano, Stefania;
Ruggiero, Dafne;
Potenza, Marianna;
Chini, Maria Giovanna;
Lauro, Gianluigi;
Fischer, Katrin;
Hofstetter, Robert Klaus;
Giordano, Assunta;
Werz, Oliver;
Bruno, Ines;
Bifulco, Giuseppe

Publication type:

Article

The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka.

Published in:

Molecules, 2020, v. 25, n. 8, p. 1894, doi. 10.3390/molecules25081894

By:

Napagoda, Mayuri;
Gerstmeier, Jana;
Butschek, Hannah;
De Soyza, Sudhara;
Pace, Simona;
Lorenz, Sybille;
Qader, Mallique;
Witharana, Sanjeeva;
Nagahawatte, Ajith;
Wijayaratne, Gaya;
Svatoš, Aleš;
Jayasinghe, Lalith;
Koeberle, Andreas;
Werz, Oliver;
Sacchetti, Gianni

Publication type:

Article

Triterpene Acids from Frankincense and Semi-Synthetic Derivatives That Inhibit 5-Lipoxygenase and Cathepsin G.

Published in:

Molecules, 2018, v. 23, n. 2, p. 506, doi. 10.3390/molecules23020506

By:

Koeberle, Andreas;
Henkel, Arne;
Verhoff, Moritz;
Tausch, Lars;
König, Stefanie;
Fischer, Dagmar;
Kather, Nicole;
Seitz, Stefanie;
Paul, Michael;
Jauch, Johann;
Werz, Oliver

Publication type:

Article

Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65215-6

By:

Stürner, Klarissa Hanja;
Werz, Oliver;
Koeberle, Andreas;
Otto, Markus;
Pless, Ole;
Leypoldt, Frank;
Paul, Friedemann;
Heesen, Christoph

Publication type:

Article

Mycobacterium tuberculosis -Induced Upregulation of the COX-2/mPGES-1 Pathway in Human Macrophages Is Abrogated by Sulfasalazine.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.849583

By:

Wang, Wenfei;
Ning, Yuping;
Wang, Yejun;
Deng, Guofang;
Pace, Simona;
Barth, Stefanie A.;
Menge, Christian;
Zhang, Kehong;
Dai, Youchao;
Cai, Yi;
Chen, Xinchun;
Werz, Oliver

Publication type:

Article

Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole‐Based Inhibitors of Soluble Epoxide Hydrolase (sEH).

Published in:

ChemPlusChem, 2024, v. 89, n. 9, p. 1, doi. 10.1002/cplu.202400234

By:

Gazzillo, Erica;
Colarusso, Ester;
Giordano, Assunta;
Chini, Maria Giovanna;
Potenza, Marianna;
Hofstetter, Robert Klaus;
Iorizzi, Maria;
Werz, Oliver;
Lauro, Gianluigi;
Bifulco, Giuseppe

Publication type:

Article

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02538-5

By:

Werz, Oliver;
Gerstmeier, Jana;
Libreros, Stephania;
la Rosa, Xavier De;
Werner, Markus;
Norris, Paul C.;
Chiang, Nan;
Serhan, Charles N.

Publication type:

Article

Matrix-based Molecular Descriptors for Prospective Virtual Compound Screening.

Published in:

Molecular Informatics, 2017, v. 36, n. 1/2, p. n/a, doi. 10.1002/minf.201600091

By:

Grisoni, Francesca;
Reker, Daniel;
Schneider, Petra;
Friedrich, Lukas;
Consonni, Viviana;
Todeschini, Roberto;
Koeberle, Andreas;
Werz, Oliver;
Schneider, Gisbert

Publication type:

Article

From Virtual Screening to Bioactive Compounds by Visualizing and Clustering of Chemical Space.

Published in:

Molecular Informatics, 2012, v. 31, n. 1, p. 21, doi. 10.1002/minf.201100147

By:

Klenner, Alexander;
Hähnke, Volker;
Geppert, Tim;
Schneider, Petra;
Zettl, Heiko;
Haller, Sarah;
Rodrigues, Tiago;
Reisen, Felix;
Hoy, Benjamin;
Schaible, Anja Maria;
Werz, Oliver;
Wessler, Silja;
Schneider, Gisbert

Publication type:

Article

A Multicomponent Carba-Betti Strategy to Alkylidene Heterodimers - Total Synthesis and Structure-Activity Relationships of Arzanol.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 4, p. 772, doi. 10.1002/ejoc.201101193

By:

Minassi, Alberto;
Cicione, Lavinia;
Koeberle, Andreas;
Bauer, Julia;
Laufer, Stefan;
Werz, Oliver;
Appendino, Giovanni

Publication type:

Article

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes.

Published in:

FASEB Journal, 2011, v. 25, n. 10, p. 3377, doi. 10.1096/fj.11-182758

By:

Pergola, Carlo;
Rogge, Anja;
Dodt, Gabriele;
Northoff, Hinnak;
Weinigel, Christina;
Barz, Dagmar;
Rådmark, Olof;
Sautebin, Lidia;
Werz, Oliver

Publication type:

Article

Phosphorylation‐ and stimulus‐dependent inhibition of cellular 5‐lipoxygenase activity by nonredox‐type inhibitors.

Published in:

FASEB Journal, 2003, v. 17, n. 8, p. 1, doi. 10.1096/fj.02-0815fje

By:

Fischer, Lutz;
Szellas, Dagmar;
Rådmark, Olof;
Steinhilber, Dieter;
Werz, Oliver

Publication type:

Article

Extracellular signal‐regulated kinases phosphorylate 5lipoxygenase and stimulate 5‐lipoxygenase product formation in leukocytes.

Published in:

FASEB Journal, 2002, v. 16, n. 11, p. 1441, doi. 10.1096/fj.01-0909fje

By:

Werz, Oliver;
Bürkert, Eva;
Fischer, Lutz;
Szellas, Dagmar;
Dishart, David;
Samuelsson, Bengt;
Rådmark, Olof;
Steinhilber, Dieter

Publication type:

Article

Specialized pro‐resolving mediators: biosynthesis and biological role in bacterial infections.

Published in:

FEBS Journal, 2022, v. 289, n. 14, p. 4212, doi. 10.1111/febs.16266

By:

Jordan, Paul M.;
Werz, Oliver

Publication type:

Article

Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors.

Published in:

ChemBioChem, 2015, v. 16, n. 17, p. 2445, doi. 10.1002/cbic.201500446

By:

Korp, Juliane;
König, Stefanie;
Schieferdecker, Sebastian;
Dahse, Hans‐Martin;
König, Gabriele M.;
Werz, Oliver;
Nett, Markus

Publication type:

Article

Protective Effect of Casperome®, an Orally Bioavailable Frankincense Extract, on Lipopolysaccharide- Induced Systemic Inflammation in Mice.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00387

By:

Loeser, Konstantin;
Seemann, Semjon;
König, Stefanie;
Lenhardt, Isabell;
Abdel-Tawab, Mona;
Koeberle, Andreas;
Werz, Oliver;
Lupp, Amelie

Publication type:

Article

Impact of Androgens on Inflammation-Related Lipid Mediator Biosynthesis in Innate Immune Cells.

Published in:

Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.01356

By:

Pace, Simona;
Werz, Oliver

Publication type:

Article

Effect of Crystallinity on the Properties of Polycaprolactone Nanoparticles Containing the Dual FLAP/mPEGS-1 Inhibitor BRP-187.

Published in:

Polymers (20734360), 2021, v. 13, n. 15, p. 2557, doi. 10.3390/polym13152557

By:

Vollrath, Antje;
Kretzer, Christian;
Beringer-Siemers, Baerbel;
Shkodra, Blerina;
Czaplewska, Justyna A.;
Bandelli, Damiano;
Stumpf, Steffi;
Hoeppener, Stephanie;
Weber, Christine;
Werz, Oliver;
Schubert, Ulrich S.

Publication type:

Article

Optimized Encapsulation of the FLAP/PGES-1 Inhibitor BRP-187 in PVA-Stabilized PLGA Nanoparticles Using Microfluidics.

Published in:

Polymers (20734360), 2020, v. 12, n. 11, p. 2751, doi. 10.3390/polym12112751

By:

Behnke, Mira;
Vollrath, Antje;
Klepsch, Lea;
Beringer-Siemers, Baerbel;
Stumpf, Steffi;
A. Czaplewska, Justyna;
Hoeppener, Stephanie;
Werz, Oliver;
S. Schubert, Ulrich

Publication type:

Article

Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures.

Published in:

2012

By:

Skarke, Carsten;
Kuczka, Karina;
Tausch, Lars;
Werz, Oliver;
Rossmanith, Tanja;
Barrett, Jeffrey S.;
Harder, Sebastian;
Holtmeier, Wolfgang;
Schwarz, Joachim A.

Publication type:

Journal Article

Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1592, doi. 10.1177/0091270011422811

By:

Skarke, Carsten;
Kuczka, Karina;
Tausch, Lars;
Werz, Oliver;
Rossmanith, Tanja;
Barrett, Jeffrey S.;
Harder, Sebastian;
Holtmeier, Wolfgang;
Schwarz, Joachim A.

Publication type:

Article

Identification of 2,4‐Dinitro‐Biphenyl‐Based Compounds as MAPEG Inhibitors.

Published in:

ChemMedChem, 2022, v. 17, n. 22, p. 1, doi. 10.1002/cmdc.202200327

By:

Di Micco, Simone;
Terracciano, Stefania;
Pierri, Martina;
Cantone, Vincenza;
Liening, Stefanie;
König, Stefanie;
Garscha, Ulrike;
Hofstetter, Robert Klaus;
Koeberle, Andreas;
Werz, Oliver;
Bruno, Ines;
Bifulco, Giuseppe

Publication type:

Article

Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.

Published in:

ChemMedChem, 2022, v. 17, n. 12, p. 1, doi. 10.1002/cmdc.202200137

By:

Çapan, İrfan;
Jordan, Paul M.;
Olğaç, Abdurrahman;
Çalışkan, Burcu;
Kretzer, Christian;
Werz, Oliver;
Banoglu, Erden

Publication type:

Article

A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4‐Thiazolidinedione‐Based Molecules as New Dual mPGES‐1/5‐LO Inhibitors.

Published in:

ChemMedChem, 2020, v. 15, n. 6, p. 481, doi. 10.1002/cmdc.201900694

By:

Lauro, Gianluigi;
Terracciano, Stefania;
Cantone, Vincenza;
Ruggiero, Dafne;
Fischer, Katrin;
Pace, Simona;
Werz, Oliver;
Bruno, Ines;
Bifulco, Giuseppe

Publication type:

Article

A Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin E<sub>2</sub> Synthase‐1 (mPGES‐1) Inhibitors.

Published in:

ChemMedChem, 2019, v. 14, n. 2, p. 273, doi. 10.1002/cmdc.201800701

By:

Shekfeh, Suhaib;
Çalışkan, Burcu;
Fischer, Katrin;
Yalçın, Tansu;
Garscha, Ulrike;
Werz, Oliver;
Banoglu, Erden

Publication type:

Article

Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity.

Published in:

Journal of Nanobiotechnology, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12951-020-00620-7

By:

Shkodra-Pula, Blerina;
Kretzer, Christian;
Jordan, Paul M.;
Klemm, Paul;
Koeberle, Andreas;
Pretzel, David;
Banoglu, Erden;
Lorkowski, Stefan;
Wallert, Maria;
Höppener, Stephanie;
Stumpf, Steffi;
Vollrath, Antje;
Schubert, Stephanie;
Werz, Oliver;
Schubert, Ulrich S.

Publication type:

Article

Synthesis of Functionalized δ-Hydroxy-β-keto Esters and Evaluation of Their Anti-inflammatory Properties.

Published in:

ChemBioChem, 2022, v. 23, n. 9, p. 1, doi. 10.1002/cbic.202200073

By:

Grosse, Michel;
Günther, Kerstin;
Jordan, Paul M.;
Roman, Dávid;
Werz, Oliver;
Beemelmanns, Christine

Publication type:

Article