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The acylphloroglucinols hyperforin and myrtucommulone A cause mitochondrial dysfunctions in leukemic cells by direct interference with mitochondria.
- Published in:
- Apoptosis, 2015, v. 20, n. 11, p. 1508, doi. 10.1007/s10495-015-1170-9
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- Publication type:
- Article
Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9.
- Published in:
- Apoptosis, 2008, v. 13, n. 1, p. 119, doi. 10.1007/s10495-007-0150-0
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- Publication type:
- Article
Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation.
- Published in:
- Advanced Science, 2023, v. 10, n. 6, p. 1, doi. 10.1002/advs.202205604
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- Publication type:
- Article
Synbiotic Bacillus megaterium DSM 32963 and n-3 PUFA Salt Composition Elevates Pro-Resolving Lipid Mediator Levels in Healthy Subjects: A Randomized Controlled Study.
- Published in:
- Nutrients, 2024, v. 16, n. 9, p. 1354, doi. 10.3390/nu16091354
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- Publication type:
- Article
Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice.
- Published in:
- Nutrients, 2023, v. 15, n. 16, p. 3660, doi. 10.3390/nu15163660
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- Publication type:
- Article
Synbiotic Compositions of Bacillus megaterium and Polyunsaturated Fatty Acid Salt Enable Self-Sufficient Production of Specialized Pro-Resolving Mediators.
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- Nutrients, 2022, v. 14, n. 11, p. 2265, doi. 10.3390/nu14112265
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- Publication type:
- Article
Olive Oil Extracts and Oleic Acid Attenuate the LPS-Induced Inflammatory Response in Murine RAW264.7 Macrophages but Induce the Release of Prostaglandin E2.
- Published in:
- Nutrients, 2021, v. 13, n. 12, p. 4437, doi. 10.3390/nu13124437
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- Publication type:
- Article
Mediterranean diet component oleic acid increases protective lipid mediators and improves trabecular bone in a Porphyromonas gingivalis inoculation model.
- Published in:
- Journal of Clinical Periodontology, 2023, v. 50, n. 3, p. 380, doi. 10.1111/jcpe.13751
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- Publication type:
- Article
Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures.
- Published in:
- 2012
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- Publication type:
- Journal Article
Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures.
- Published in:
- Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1592, doi. 10.1177/0091270011422811
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- Publication type:
- Article
A Multicomponent Carba-Betti Strategy to Alkylidene Heterodimers - Total Synthesis and Structure-Activity Relationships of Arzanol.
- Published in:
- European Journal of Organic Chemistry, 2012, v. 2012, n. 4, p. 772, doi. 10.1002/ejoc.201101193
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- Publication type:
- Article
15‐Hydroperoxy‐PGE<sub>2</sub>: Intermediate in Mammalian and Algal Prostaglandin Biosynthesis.
- Published in:
- Angewandte Chemie International Edition, 2019, v. 58, n. 49, p. 17641, doi. 10.1002/anie.201910461
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- Publication type:
- Article
Algal Oxylipins Mediate the Resistance of Diatoms against Algicidal Bacteria.
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- Marine Drugs, 2018, v. 16, n. 12, p. 486, doi. 10.3390/md16120486
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- Publication type:
- Article
Strukturrevision einer weit verbreiteten marinen Sulfonolipidklasse basierend auf deren Isolierung und Totalsynthese.
- Published in:
- Angewandte Chemie, 2024, v. 136, n. 23, p. 1, doi. 10.1002/ange.202401195
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- Publication type:
- Article
15‐Hydroperoxy‐PGE<sub>2</sub>: Intermediate in Mammalian and Algal Prostaglandin Biosynthesis.
- Published in:
- Angewandte Chemie, 2019, v. 131, n. 49, p. 17805, doi. 10.1002/ange.201910461
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- Publication type:
- Article
Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.
- Published in:
- Aging Cell, 2023, v. 22, n. 7, p. 1, doi. 10.1111/acel.13856
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- Publication type:
- Article
Anti-Inflammatory Activities of Arnica montana Planta Tota versus Flower Extracts: Analytical, In Vitro and In Vivo Mouse Paw Oedema Model Studies.
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- Plants (2223-7747), 2023, v. 12, n. 6, p. 1348, doi. 10.3390/plants12061348
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- Publication type:
- Article
In Silico, In Vitro and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from Salvia miltiorrhiza as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 1, p. 99, doi. 10.3390/biom12010099
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- Publication type:
- Article
Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides.
- Published in:
- Biomolecules (2218-273X), 2021, v. 11, n. 5, p. 746, doi. 10.3390/biom11050746
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- Publication type:
- Article
Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms.
- Published in:
- Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.937466
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- Publication type:
- Article
Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 20, p. 12555, doi. 10.1093/nar/gku1033
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- Publication type:
- Article
Total Synthesis of Myrtucommulone A.
- Published in:
- Angewandte Chemie International Edition, 2010, v. 49, n. 11, p. 2045, doi. 10.1002/anie.200903906
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- Publication type:
- Article
Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations.
- Published in:
- Cellular & Molecular Life Sciences, 2010, v. 67, n. 5, p. 797, doi. 10.1007/s00018-009-0206-0
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- Publication type:
- Article
Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo.
- Published in:
- Cellular & Molecular Life Sciences, 2009, v. 66, n. 16, p. 2759, doi. 10.1007/s00018-009-0078-3
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- Publication type:
- Article
Vitamin A regulates Akt signaling through the phospholipid fatty acid composition.
- Published in:
- FASEB Journal, 2017, v. 31, n. 10, p. 4566, doi. 10.1096/fj.201700078R
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- Publication type:
- Article
5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation.
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- FASEB Journal, 2016, v. 30, n. 5, p. 1892, doi. 10.1096/fj.201500210R
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- Publication type:
- Article
Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes.
- Published in:
- FASEB Journal, 2016, v. 30, n. 1, p. 276, doi. 10.1096/fj.15-278010
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- Publication type:
- Article
Role of p38 mitogen-activated protein kinase in linking stearoyl-CoA desaturase-1 activity with endoplasmic reticulum homeostasis.
- Published in:
- FASEB Journal, 2015, v. 29, n. 6, p. 2439, doi. 10.1096/fj.14-268474
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- Publication type:
- Article
Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes.
- Published in:
- FASEB Journal, 2011, v. 25, n. 10, p. 3377, doi. 10.1096/fj.11-182758
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- Publication type:
- Article
Phosphorylation‐ and stimulus‐dependent inhibition of cellular 5‐lipoxygenase activity by nonredox‐type inhibitors.
- Published in:
- FASEB Journal, 2003, v. 17, n. 8, p. 1, doi. 10.1096/fj.02-0815fje
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- Publication type:
- Article
Specialized pro‐resolving mediators: biosynthesis and biological role in bacterial infections.
- Published in:
- FEBS Journal, 2022, v. 289, n. 14, p. 4212, doi. 10.1111/febs.16266
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- Publication type:
- Article
Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors.
- Published in:
- ChemBioChem, 2015, v. 16, n. 17, p. 2445, doi. 10.1002/cbic.201500446
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- Publication type:
- Article
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation.
- Published in:
- Molecules, 2022, v. 27, n. 12, p. 3866, doi. 10.3390/molecules27123866
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- Publication type:
- Article
The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka.
- Published in:
- Molecules, 2020, v. 25, n. 8, p. 1894, doi. 10.3390/molecules25081894
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- Publication type:
- Article
Triterpene Acids from Frankincense and Semi-Synthetic Derivatives That Inhibit 5-Lipoxygenase and Cathepsin G.
- Published in:
- Molecules, 2018, v. 23, n. 2, p. 506, doi. 10.3390/molecules23020506
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- Publication type:
- Article
A tiered approach to investigate the mechanism of anti-inflammatory activity of an herbal medicinal product containing a fixed combination of thyme herb and primula root extracts.
- Published in:
- Clinical Phytoscience, 2018, v. 4, n. 1, p. 0, doi. 10.1186/s40816-018-0062-2
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- Publication type:
- Article
Vitex agnus-castus dry extract BNO 1095 (Agnucaston) inhibits uterine hyper-contractions and inflammation in experimental models for primary dysmenorrhea.
- Published in:
- Clinical Phytoscience, 2016, v. 2, n. 1, p. 1, doi. 10.1186/s40816-016-0034-3
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- Publication type:
- Article
Controlled Release of the α-Tocopherol-Derived Metabolite α-13′-Carboxychromanol from Bacterial Nanocellulose Wound Cover Improves Wound Healing.
- Published in:
- Nanomaterials (2079-4991), 2021, v. 11, n. 8, p. 1939, doi. 10.3390/nano11081939
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- Publication type:
- Article
Modified Bacterial Cellulose Dressings to Treat Inflammatory Wounds.
- Published in:
- Nanomaterials (2079-4991), 2020, v. 10, n. 12, p. 2508, doi. 10.3390/nano10122508
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- Publication type:
- Article
Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis.
- Published in:
- Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.818544
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- Publication type:
- Article
Hyphal‐associated protein expression is crucial for Candida albicans‐induced eicosanoid biosynthesis in immune cells.
- Published in:
- European Journal of Immunology, 2024, v. 54, n. 3, p. 1, doi. 10.1002/eji.202350743
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- Publication type:
- Article
Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis.
- Published in:
- Cellular & Molecular Life Sciences, 2020, v. 77, n. 21, p. 4365, doi. 10.1007/s00018-019-03413-w
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- Publication type:
- Article
Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis.
- Published in:
- Cellular & Molecular Life Sciences, 2020, v. 77, n. 19, p. 3841, doi. 10.1007/s00018-019-03393-x
- By:
- Publication type:
- Article
Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.
- Published in:
- British Journal of Cancer, 2018, v. 118, n. 1, p. 43, doi. 10.1038/bjc.2017.374
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- Publication type:
- Article
Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.
- Published in:
- 2017
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- Publication type:
- journal article
Small molecules intercept Notch signaling and the early secretory pathway.
- Published in:
- Nature Chemical Biology, 2013, v. 9, n. 11, p. 731, doi. 10.1038/nchembio.1356
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- Publication type:
- Article
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
- Published in:
- Nature Chemical Biology, 2012, v. 8, n. 2, p. 141, doi. 10.1038/nchembio.761
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- Publication type:
- Article
Correction: Encapsulation of the dual FLAP/mPEGS‑1 inhibitor BRP‑187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity.
- Published in:
- 2024
- By:
- Publication type:
- Correction Notice
Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity.
- Published in:
- Journal of Nanobiotechnology, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12951-020-00620-7
- By:
- Publication type:
- Article
Connecting lysosomes and mitochondria – a novel role for lipid metabolism in cancer cell death.
- Published in:
- Cell Communication & Signaling, 2019, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12964-019-0399-2
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- Publication type:
- Article