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Standardized assays to monitor drug sensitivity in hematologic cancers.
- Published in:
- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01722-5
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- Publication type:
- Article
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies.
- Published in:
- Scientific Reports, 2014, p. 1, doi. 10.1038/srep05193
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- Publication type:
- Article
β1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts.
- Published in:
- Oncogene, 1999, v. 18, n. 26, p. 3852, doi. 10.1038/sj.onc.1202770
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- Publication type:
- Article
MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity.
- Published in:
- FEBS Letters, 2015, v. 589, n. 24PartB, p. 3859, doi. 10.1016/j.febslet.2015.11.013
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- Publication type:
- Article
Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data.
- Published in:
- Nucleic Acids Research, 2023, v. 51, n. W1, p. W57, doi. 10.1093/nar/gkad390
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- Publication type:
- Article
A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury.
- Published in:
- Nature Communications, 2017, v. 8, n. 7, p. 15932, doi. 10.1038/ncomms15932
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- Publication type:
- Article
c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson's Disease.
- Published in:
- Frontiers in Aging Neuroscience, 2016, v. 8, p. 1, doi. 10.3389/fnagi.2016.00254
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- Publication type:
- Article
Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 562, p. 1, doi. 10.1126/scitranslmed.aba4434
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- Publication type:
- Article
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells.
- Published in:
- Science Translational Medicine, 2018, v. 10, n. 450, p. 1, doi. 10.1126/scitranslmed.aaq1093
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- Publication type:
- Article
Identification of novel small molecule activators of nuclear factor-κb with neuroprotective action via high-throughput screening.
- Published in:
- Journal of Neuroscience Research, 2011, v. 89, n. 1, p. 58, doi. 10.1002/jnr.22526
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- Publication type:
- Article
Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs.
- Published in:
- BMC Bioinformatics, 2012, v. 13, n. 1, p. 112, doi. 10.1186/1471-2105-13-112
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- Publication type:
- Article
GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-68626-x
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- Publication type:
- Article
Drug Target Commons 2.0: a community platform for systematic analysis of drug–target interaction profiles.
- Published in:
- Database: The Journal of Biological Databases & Curation, 2018, v. 2018, p. 1, doi. 10.1093/database/bay083
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- Publication type:
- Article
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia.
- Published in:
- NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00209-9
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- Publication type:
- Article
Minimal information for chemosensitivity assays (MICHA): a next-generation pipeline to enable the FAIRification of drug screening experiments.
- Published in:
- Briefings in Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1093/bib/bbab350
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- Publication type:
- Article
Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer.
- Published in:
- Briefings in Bioinformatics, 2021, v. 22, n. 6, p. 1, doi. 10.1093/bib/bbab272
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- Publication type:
- Article
Exploration of databases and methods supporting drug repurposing: a comprehensive survey.
- Published in:
- Briefings in Bioinformatics, 2021, v. 22, n. 2, p. 1656, doi. 10.1093/bib/bbaa003
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- Publication type:
- Article
Interactive visual analysis of drug–target interaction networks using Drug Target Profiler, with applications to precision medicine and drug repurposing.
- Published in:
- Briefings in Bioinformatics, 2020, v. 21, n. 1, p. 211, doi. 10.1093/bib/bby119
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- Publication type:
- Article
Feasibility study of using high-throughput drug sensitivity testing to target recurrent glioblastoma stem cells for individualized treatment.
- Published in:
- Clinical & Translational Medicine, 2019, v. 8, n. 1, p. 1, doi. 10.1186/s40169-019-0253-6
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- Publication type:
- Article
Feasibility study of using high‐throughput drug sensitivity testing to target recurrent glioblastoma stem cells for individualized treatment.
- Published in:
- Clinical & Translational Medicine, 2019, v. 8, n. 1, p. 1, doi. 10.1186/s40169-019-0253-6
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- Publication type:
- Article
Robust scoring of selective drug responses for patient-tailored therapy selection.
- Published in:
- Nature Protocols, 2024, v. 19, n. 1, p. 60, doi. 10.1038/s41596-023-00903-x
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- Publication type:
- Article
PP2A‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 9, p. 1803, doi. 10.1002/1878-0261.13488
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- Publication type:
- Article
PI3Kβ inhibition enhances ALK‐inhibitor sensitivity in ALK‐rearranged lung cancer.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 5, p. 747, doi. 10.1002/1878-0261.13342
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- Publication type:
- Article
Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways.
- Published in:
- PLoS Computational Biology, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.pcbi.1003226
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- Publication type:
- Article
Breeze: an integrated quality control and data analysis application for high-throughput drug screening.
- Published in:
- Bioinformatics, 2020, v. 36, n. 11, p. 3602, doi. 10.1093/bioinformatics/btaa138
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- Publication type:
- Article
Global proteomics profiling improves drug sensitivity prediction: results from a multi-omics, pan-cancer modeling approach.
- Published in:
- Bioinformatics, 2018, v. 34, n. 8, p. 1353, doi. 10.1093/bioinformatics/btx766
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- Publication type:
- Article
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer.
- Published in:
- NPJ Systems Biology & Applications, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41540-019-0098-z
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- Publication type:
- Article
ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors.
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- Journal of Pathology, 2020, v. 250, n. 2, p. 159, doi. 10.1002/path.5356
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- Publication type:
- Article
Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation.
- Published in:
- Nature, 2015, v. 519, n. 7541, p. 102, doi. 10.1038/nature14119
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- Publication type:
- Article
Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer.
- Published in:
- Clinical Epigenetics, 2019, v. 11, n. 1, p. 1, doi. 10.1186/s13148-019-0781-3
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- Publication type:
- Article
Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma.
- Published in:
- NAR Cancer, 2023, v. 5, n. 3, p. 1, doi. 10.1093/narcan/zcad029
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- Publication type:
- Article
Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.73760
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- Publication type:
- Article
Seed-effect modeling improves the consistency of genome-wide loss-offunction screens and identifies synthetic lethal vulnerabilities in cancer cells.
- Published in:
- Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0440-2
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- Publication type:
- Article
Bioluminescent, Nonlytic, Real-Time Cell Viability Assay and Use in Inhibitor Screening.
- Published in:
- Assay & Drug Development Technologies, 2015, v. 13, n. 8, p. 456, doi. 10.1089/adt.2015.669
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- Publication type:
- Article
Bioluminescent Cell-Based NAD(P)/NAD(P)H Assays for Rapid Dinucleotide Measurement and Inhibitor Screening.
- Published in:
- Assay & Drug Development Technologies, 2014, v. 12, n. 9/10, p. 514, doi. 10.1089/adt.2014.605
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- Publication type:
- Article
A High-Throughput Screen for Chemical Inhibitors of Exocytic Transport in Yeast.
- Published in:
- ChemBioChem, 2010, v. 11, n. 9, p. 1291, doi. 10.1002/cbic.200900681
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- Publication type:
- Article
Systematic identification of feature combinations for predicting drug response with Bayesian multi-view multi-task linear regression.
- Published in:
- Bioinformatics, 2017, v. 33, n. 14, p. i359, doi. 10.1093/bioinformatics/btx266
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- Publication type:
- Article
Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data.
- Published in:
- Bioinformatics, 2015, v. 31, n. 23, p. 3815, doi. 10.1093/bioinformatics/btv455
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- Publication type:
- Article
TIMMA-R: an R package for predicting synergistic multi-targeted drug combinations in cancer cell lines or patient-derived samples.
- Published in:
- 2015
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- Publication type:
- Product Review
Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis.
- Published in:
- Bioinformatics, 2014, v. 30, n. 17, p. i497, doi. 10.1093/bioinformatics/btu456
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- Publication type:
- Article
A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening.
- Published in:
- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0765-z
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- Publication type:
- Article
Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.954430
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- Publication type:
- Article
Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing.
- Published in:
- Cancers, 2020, v. 12, n. 1, p. 92, doi. 10.3390/cancers12010092
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- Publication type:
- Article
Identification of novel regulators of STAT3 activity.
- Published in:
- PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0230819
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- Publication type:
- Article
8‐chloro‐adenosine activity in FLT3‐ITD acute myeloid leukemia.
- Published in:
- Journal of Cellular Physiology, 2019, v. 234, n. 9, p. 16295, doi. 10.1002/jcp.28294
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- Publication type:
- Article
Novel Screening Method Identifies PI3Kα, mTOR, and IGF1R as Key Kinases Regulating Cardiomyocyte Survival.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18118-7
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- Publication type:
- Article
Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naïve glioblastoma.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors.
- Published in:
- PLoS Computational Biology, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pcbi.1005678
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- Publication type:
- Article
What is synergy? The Saariselkä agreement revisited.
- Published in:
- Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00181
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- Publication type:
- Article