Works matching AU Wengel, Jesper

Results: 116

A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids.

Published in:

Angewandte Chemie, 2013, v. 125, n. 47, p. 12567, doi. 10.1002/ange.201307661

By:

Xu, Liang;
Plouffe, Steven W.;
Chong, Jenny;
Wengel, Jesper;
Wang, Dong

Publication type:

Article

Innentitelbild: A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids (Angew. Chem. 47/2013).

Published in:

Angewandte Chemie, 2013, v. 125, n. 47, p. 12418, doi. 10.1002/ange.201309065

By:

Xu, Liang;
Plouffe, Steven W.;
Chong, Jenny;
Wengel, Jesper;
Wang, Dong

Publication type:

Article

Photoinduzierter reduktiver Elektronentransfer in LNA:DNA-Hybriden: Kompromiss aus Konformation und Basenstapelung.

Published in:

Angewandte Chemie, 2012, v. 124, n. 40, p. 10168, doi. 10.1002/ange.201204901

By:

Wenge, Ulrike;
Wengel, Jesper;
Wagenknecht, Hans-Achim

Publication type:

Article

Dual-Probe System Using Pyrenylmethyl-Modified Amino-Lna for Mismatch Detection.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 10-12, p. 1261, doi. 10.1080/15257770701528255

By:

Umemoto, Tadashi;
Hrdlicka, PatrickJ.;
Babu, B.Ravindra;
Wengel, Jesper

Publication type:

Article

Synthesis and Biophysical Studies of N2'-Functionalized 2'-Amino-α-L-LNA.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 10-12, p. 1403, doi. 10.1080/15257770701538841

By:

Kumar, T.Santhosh;
Madsen, AndreasS.;
Wengel, Jesper;
Hrdlicka, PatrickJ.

Publication type:

Article

Pyrene-Functionalized 2 '-Amino-α-L-LNA as Potential Diagnostic Probes.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 10-12, p. 1407, doi. 10.1080/15257770701538908

By:

Kumar, T.Santhosh;
Wengel, Jesper;
Hrdlicka, PatrickJ.

Publication type:

Article

Triplex-Forming Ability of Modified Oligonucleotides.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 10-12, p. 1411, doi. 10.1080/15257770701539047

By:

Højland, Torben;
Babu, B.Ravindra;
Bryld, Torsten;
Wengel, Jesper

Publication type:

Article

N2'-Functionalized 2'-Amino-α-L-LNA Adenine Derivatives - Efficient Targeting of Single Stranded DNA.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 10-12, p. 1415, doi. 10.1080/15257770701539153

By:

Andersen, NicolaiK.;
Wengel, Jesper;
Hrdlicka, PatrickJ.

Publication type:

Article

Novel Selective Biocatalytic Deacylation Studies on Key Precursors for Bicyclonucleosides.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 10-12, p. 1517, doi. 10.1080/15257770701544302

By:

Prasad, AshokK.;
Singh, SunilK.;
Kalra, Neerja;
Singhal, Nidhi;
Wengel, Jesper;
Parmar, VirinderS.

Publication type:

Article

In Vitro Incorporation of LNA Nucleotides.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 8/9, p. 1207, doi. 10.1080/15257770701527844

By:

Veedu, RakeshN.;
Vester, Birte;
Wengel, Jesper

Publication type:

Article

Synthesis of a 2′-Amino- α -l-LNA-T Phosphoramidite.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2005, v. 24, n. 5-7, p. 1101, doi. 10.1080/15257770500276866

By:

Hrdlicka, Patrick J.;
Kumar, T. Santhosh;
Wengel, Jesper

Publication type:

Article

DNA Self-Assembling Systems: Branched Oligonucleotides as Building Blocks and Monitoring by Pyrene Excimer Band Formation.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2005, v. 24, n. 5-7, p. 679, doi. 10.1081/NCN-200060247

By:

Lindegaard, Dorthe;
Babu, B. Ravindra;
Wengel, Jesper

Publication type:

Article

Synthesis and Biological Evaluation of Conformationally Restricted and Nucleobase-Modified Analogs of the Anticancer Compound 3′-C-Ethynylcytidine (ECYD).

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2005, v. 24, n. 5-7, p. 397, doi. 10.1081/NCN-200059821

By:

Hrdlicka, Patrick J.;
Jepsen, Jan S.;
Wengel, Jesper

Publication type:

Article

LNA and α-L-LNA: Towards Therapeutic Applications.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 601, doi. 10.1081/NCN-120021963

By:

Wengel, Jesper;
Vester, Birte;
Lundberg, Lars Bo;
Douthwaite, Stephen;
Sørensen, Mads D.;
Ravindra Babu, B.;
Gait, Michael J.;
Arzumanov, Andrey;
Petersen, Michael;
Nielsen, Jakob T.

Publication type:

Article

Synthesis of an Asymmetrically Substituted AZA Crown Ether as Metal and Amino Acid Binding Site in DNA Conjugates.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1039, doi. 10.1081/NCN-120022730

By:

Vogel, Stefan;
Rohr, Katja;
Dahl, Otto;
Wengel, Jesper

Publication type:

Article

Improved Synthesis of 2′-Amino-LNA.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1131, doi. 10.1081/NCN-120022818

By:

Christensen, Signe M.;
Rosenbohm, Christoph;
Sørensen, Mads;
Larsen, Lotte-Emilie;
Wengel, Jesper;
Koch, Troels

Publication type:

Article

xylo-Configured Oligonucleotides (XNA, Xylo Nucleic Acids): Synthesis and Hybridization Studies.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1147, doi. 10.1081/NCN-120022822

By:

Poopeiko, Nicolai E.;
Dahl, Britta M.;
Wengel, Jesper

Publication type:

Article

Synthesis of a Base-Protected α-L-LNA Guanine Nucleoside.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1155, doi. 10.1081/NCN-120022824

By:

Gaubert, Gilles;
Wengel, Jesper

Publication type:

Article

Synthesis and Hybridization Properties of Oligodeoxynucleotides Containing 3′-Deoxy-3′-C-methyleneuridine.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1159, doi. 10.1081/NCN-120022825

By:

Lindegaard, Dorthe;
Wengel, Jesper

Publication type:

Article

Synthesis of a Base-Protected xylo-LNA Adenine Nucleoside.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1163, doi. 10.1081/NCN-120022826

By:

Bryld, Torsten;
Wengel, Jesper

Publication type:

Article

Aryl-β-C-LNA Monomers as Universal Hybridization Probes12.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1317, doi. 10.1081/NCN-120022955

By:

Ravindra Babu, B.;
Wengel, Jesper

Publication type:

Article

Synthesis of 2′-Spiro Ribo- and Arabinonucleosides.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1313, doi. 10.1081/NCN-120022954

By:

Ravindra Babu, B.;
Keinicke, Lise;
Wengel, Jesper

Publication type:

Article

Structural Characterization of LNA and α-L-LNA Hybridized to RNA.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1691, doi. 10.1081/NCN-120023115

By:

Petersen, Michael;
Nielsen, Jakob T.;
Bondensgaard, Kent;
Wengel, Jesper;
Jacobsen, Jens Peter

Publication type:

Article

LNA (LOCKED NUCLEIC ACID) AND THE DIASTEREOISOMERIC α-L-LNA: CONFORMATIONAL TUNING AND HIGH-AFFINITY RECOGNITION OF DNA/RNA TARGETS.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 389, doi. 10.1081/NCN-100002312

By:

Wengel, Jesper;
Petersen, Michael;
Nielsen, KathrineE.;
Jensen, GitteA.;
Håkansson, AndersE.;
Kumar, Ravindra;
Sørensen, MadsD.;
Rajwanshi, VivekK.;
Bryld, Torsten;
Jacobsen, JensPeter

Publication type:

Article

OLIGONUCLEOTIDE ANALOGUE INTERFERENCE WITH THE HIV-1 TAT PROTEIN-TAR RNA INTERACTION.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 471, doi. 10.1081/NCN-100002321

By:

Arzumanov, Andrey;
Walsh, AndrewP.;
Liu, Xiaohai;
Rajwanshi, VivekK.;
Wengel, Jesper;
Gait, MichaelJ.

Publication type:

Article

Improved silencing properties using small internally segmented interfering RNAs.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 17, p. 5886, doi. 10.1093/nar/gkm548

By:

Bramsen, Jesper B.;
Laursen, Maria B.;
Damgaard, Christian K.;
Lena, Suzy W.;
Ravindra Babu, B.;
Wengel, Jesper;
Kjems, Jørgen

Publication type:

Article

Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 13, p. 4223, doi. 10.1093/nar/gki726

By:

Brunet, Erika;
Corgnali, Maddalena;
Perrouault, Loïc;
Roig, Victoria;
Asseline, Ulysse;
Sørensen, Mads D.;
Babu, B. Ravindra;
Wengel, Jesper;
Giovannangeli, Carine

Publication type:

Article

Transcription factor decoy oligonucleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 6, p. 1874, doi. 10.1093/nar/gkh503

By:

Crinelli, Rita;
Bianchi, Marzia;
Gentilini, Lucia;
Palma, Linda;
Sørensen, Mads D.;
Bryld, Torsten;
Babu, Ravindra B.;
Arar, Khalil;
Wengel, Jesper;
Magnani, Mauro

Publication type:

Article

Analogues of the antibiotic puromycin as potential prodrugs of 3′-amino-3′-deoxythymidine.

Published in:

Journal of Heterocyclic Chemistry, 1992, v. 29, n. 1, p. 5, doi. 10.1002/jhet.5570290102

By:

Wengel, Jesper;
Motawia, Mohammed S.;
Pedersen, Erik B.;
Nielsen, Carsten M.

Publication type:

Article

Palmitoylated phosphodiester gapmer designs with albumin binding capacity and maintained in vitro gene silencing activity.

Published in:

Journal of Gene Medicine, 2018, v. 20, n. 7/8, p. 1, doi. 10.1002/jgm.3025

By:

Cai, Yunpeng;
Makarova, Anna‐Marie;
Wengel, Jesper;
Howard, Kenneth A.

Publication type:

Article

Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides.

Published in:

Molecules, 2019, v. 24, n. 21, p. 3922, doi. 10.3390/molecules24213922

By:

Yadav, Yogesh;
Sharma, Deepti;
Kaushik, Kumar;
Kumar, Vineet;
Jha, Amitabh;
Prasad, Ashok K.;
Len, Christophe;
Malhotra, Sanjay V.;
Wengel, Jesper;
Parmar, Virinder S.

Publication type:

Article

Oligonucleotide Binding to Non-B-DNA in MYC.

Published in:

Molecules, 2019, v. 24, n. 5, p. 1000, doi. 10.3390/molecules24051000

By:

Umek, Tea;
Sollander, Karin;
Bergquist, Helen;
Wengel, Jesper;
Lundin, Karin E.;
Smith, C.I. Edvard;
Zain, Rula;
Strömberg, Roger

Publication type:

Article

Synthesis and Excellent Duplex Stability of Oligonucleotides Containing 2′-Amino-LNA Functionalized with Galactose Units.

Published in:

Molecules, 2017, v. 22, n. 5, p. 852, doi. 10.3390/molecules22050852

By:

Kumar, Rajesh;
Ries, Annika;
Wengel, Jesper

Publication type:

Article

Amplification and Re-Generation of LNA-Modified Libraries.

Published in:

Molecules, 2012, v. 17, n. 11, p. 13087, doi. 10.3390/molecules171113087

By:

Doessing, Holger;
Hansen, Lykke H.;
Veedu, Rakesh N.;
Wengel, Jesper;
Vester, Birte

Publication type:

Article

MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells.

Published in:

RNA Biology, 2018, v. 15, n. 10, p. 1273, doi. 10.1080/15476286.2018.1526536

By:

Ferino, Annalisa;
Miglietta, Giulia;
Picco, Raffaella;
Vogel, Stefan;
Wengel, Jesper;
Xodo, Luigi E.

Publication type:

Article

Development of an Efficient G-Quadruplex-Stabilised Thrombin-Binding Aptamer Containing a Three-Carbon Spacer Molecule.

Published in:

ChemBioChem, 2017, v. 18, n. 8, p. 755, doi. 10.1002/cbic.201600654

By:

Aaldering, Lukas J.;
Poongavanam, Vasanthanathan;
Langkjær, Niels;
Murugan, N. Arul;
Jørgensen, Per Trolle;
Wengel, Jesper;
Veedu, Rakesh N.

Publication type:

Article

Unlocked Nucleic Acids with a Pyrene-Modified Uracil: Synthesis, Hybridization Studies, Fluorescent Properties and i-Motif Stability.

Published in:

ChemBioChem, 2014, v. 15, n. 1, p. 146, doi. 10.1002/cbic.201300567

By:

Perlíková, Pavla;
Karlsen, Kasper K.;
Pedersen, Erik B.;
Wengel, Jesper

Publication type:

Article

Novel (Phenylethynyl)pyrene-LNA Constructs for Fluorescence SNP Sensing in Polymorphic Nucleic Acid Targets.

Published in:

ChemBioChem, 2012, v. 13, n. 10, p. 1509, doi. 10.1002/cbic.201200079

By:

Astakhova, Irina Kira;
Samokhina, Evgeniya;
Babu, B. Ravindra;
Wengel, Jesper

Publication type:

Article

Pyrene-Modified Unlocked Nucleic Acids: Synthesis, Thermodynamic Studies, and Fluorescent Properties.

Published in:

ChemBioChem, 2012, v. 13, n. 4, p. 590, doi. 10.1002/cbic.201100689

By:

Karlsen, Kasper K.;
Pasternak, Anna;
Jensen, Troels B.;
Wengel, Jesper

Publication type:

Article

Synthesis and Structural Characterization of 2′-Fluoro-α- L-RNA-Modified Oligonucleotides.

Published in:

ChemBioChem, 2011, v. 12, n. 12, p. 1904, doi. 10.1002/cbic.201100161

By:

Bundgaard Jensen, Troels;
Pasternak, Anna;
Stahl Madsen, Andreas;
Petersen, Michael;
Wengel, Jesper

Publication type:

Article

Minimal Substrate Features for Erm Methyltransferases Defined by Using a Combinatorial Oligonucleotide Library.

Published in:

ChemBioChem, 2011, v. 12, n. 4, p. 610, doi. 10.1002/cbic.201000606

By:

Hansen, Lykke H.;
Lobedanz, Sune;
Douthwaite, Stephen;
Arar, Khalil;
Wengel, Jesper;
Kirpekar, Finn;
Vester, Birte

Publication type:

Article

Sensitive SNP Dual-Probe Assays Based on Pyrene-Functionalized 2′-Amino-LNA: Lessons To Be Learned.

Published in:

ChemBioChem, 2007, v. 8, n. 18, p. 2240, doi. 10.1002/cbic.200700408

By:

Umemoto, Tadashi;
Hrdlicka, Patrick J.;
Babu, B. Ravindra;
Wengel, Jesper

Publication type:

Article

2′- N-(Pyren-1-yl)acetyl-2′-Amino-α-L-LNA: Synthesis and Detection of Single Nucleotide Mismatches in DNA and RNA Targets.

Published in:

ChemBioChem, 2007, v. 8, n. 10, p. 1122, doi. 10.1002/cbic.200700144

By:

Kumar, T. Santhosh;
Wengel, Jesper;
Hrdlicka, Patrick J.

Publication type:

Article

Enzymatic Incorporation of LNA Nucleotides into DNA Strands.

Published in:

ChemBioChem, 2007, v. 8, n. 5, p. 490, doi. 10.1002/cbic.200600501

By:

Veedu, Rakesh N.;
Vester, Birte;
Wengel, Jesper

Publication type:

Article

Enhanced Inhibition of Transcription Start by Targeting with 2′-OMe Pentaribonucleotides Comprising Locked Nucleic Acids and Intercalating Nucleic Acids.

Published in:

ChemBioChem, 2005, v. 6, n. 7, p. 1181, doi. 10.1002/cbic.200400457

By:

Vyacheslav V. Filichev;
Birte Vester;
Lykke H. Hansen;
Mohammed T. Abdel Aal;
B. Ravindra Babu;
Jesper Wengel;
Erik B. Pedersen

Publication type:

Article

Locked Nucleic Acids and Intercalating Nucleic Acids in the Design of Easily Denaturing Nucleic Acids: Thermal Stability Studies.

Published in:

ChemBioChem, 2004, v. 5, n. 12, p. 1673, doi. 10.1002/cbic.200400222

By:

Vyacheslav V. Filichev;
Ulf B. Christensen;
Erik B. Pedersen;
B. Ravindra Babu;
Jesper Wengel

Publication type:

Article

Cover Picture: Locked Nucleic Acids and Intercalating Nucleic Acids in the Design of Easily Denaturing Nucleic Acids: Thermal Stability Studies (ChemBioChem 12/2004).

Published in:

ChemBioChem, 2004, v. 5, n. 12, p. 1613, doi. 10.1002/cbic.200490045

By:

Vyacheslav V. Filichev;
Ulf B. Christensen;
Erik B. Pedersen;
B. Ravindra Babu;
Jesper Wengel

Publication type:

Article

Application of locked nucleic acid-based probes in fluorescence in situ hybridization.

Published in:

Applied Microbiology & Biotechnology, 2016, v. 100, n. 13, p. 5897, doi. 10.1007/s00253-016-7429-4

By:

Fontenete, Sílvia;
Carvalho, Daniel;
Guimarães, Nuno;
Madureira, Pedro;
Figueiredo, Céu;
Wengel, Jesper;
Azevedo, Nuno

Publication type:

Article

Mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 9, p. 3961, doi. 10.1007/s00253-015-6389-4

By:

Silvia, Fontenete;
Joana, Barros;
Pedro, Madureira;
Céu, Figueiredo;
Jesper, Wengel;
Filipe, Azevedo

Publication type:

Article

Erratum to: Mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids.

Published in:

2015

By:

Fontenete, Silvia;
Barros, Joana;
Madureira, Pedro;
Figueiredo, Céu;
Wengel, Jesper;
Azevedo, Nuno

Publication type:

Erratum