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Polyamine–Oligonucleotide Conjugates: 2′- O Me-Triazole-Linked 1,4,7,10-Tetraazacyclododecane and Intercalating Dyes and Their Effect on the Thermal Stability of DNA Duplexes.
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- Pharmaceutics, 2022, v. 14, n. 1, p. 66, doi. 10.3390/pharmaceutics14010066
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- Article
Intramuscular Evaluation of Chimeric Locked Nucleic Acid/2′ O Methyl-Modified Antisense Oligonucleotides for Targeted Exon 23 Skipping in Mdx Mice.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 11, p. 1113, doi. 10.3390/ph14111113
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- Article
Brightness through Local Constraint-LNA-Enhanced FIT Hybridization Probes for In Vivo Ribonucleotide Particle Tracking.
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- Angewandte Chemie International Edition, 2014, v. 53, n. 42, p. 11370, doi. 10.1002/anie.201406022
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- Article
A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids.
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- Angewandte Chemie International Edition, 2013, v. 52, n. 47, p. 12341, doi. 10.1002/anie.201307661
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- Article
Inside Cover: A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids (Angew. Chem. Int. Ed. 47/2013).
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- Angewandte Chemie International Edition, 2013, v. 52, n. 47, p. 12196, doi. 10.1002/anie.201309065
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- Article
Alpha-l-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2434, doi. 10.3390/ijms21072434
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- Article
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model.
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- Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4067, doi. 10.1172/JCI76175
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- Article
Can Vitamin B12 Assist the Internalization of Antisense LNA Oligonucleotides into Bacteria?
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- Antibiotics (2079-6382), 2021, v. 10, n. 4, p. 379, doi. 10.3390/antibiotics10040379
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- Article
CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression.
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- Nucleic Acids Research, 2017, v. 45, n. 9, p. 5153, doi. 10.1093/nar/gkx111
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- Article
Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.
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- Nucleic Acids Research, 2016, v. 44, n. 5, p. 2007, doi. 10.1093/nar/gkw021
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- Article
Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues.
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- Nucleic Acids Research, 2015, v. 43, n. 9, p. 5863, doi. 10.1093/nar/gku238
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- Article
Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues.
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- Nucleic Acids Research, 2014, v. 42, n. 9, p. 5863, doi. 10.1093/nar/gku238
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- Article
G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold.
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- Nucleic Acids Research, 2013, v. 41, n. 20, p. 9524
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- Article
Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.
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- Nucleic Acids Research, 2013, v. 41, n. 5, p. 3257, doi. 10.1093/nar/gkt007
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- Article
In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important.
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- Nucleic Acids Research, 2012, v. 40, n. 10, p. 4653, doi. 10.1093/nar/gks033
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- Article
Synthesis and structural characterization of piperazino-modified DNA that favours hybridization towards DNA over RNA.
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- Nucleic Acids Research, 2011, v. 39, n. 5, p. 1953, doi. 10.1093/nar/gkq1123
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- Article
Optimizing anti-gene oligonucleotide ‘Zorro-LNA’ for improved strand invasion into duplex DNA.
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- Nucleic Acids Research, 2011, v. 39, n. 3, p. 1142, doi. 10.1093/nar/gkq835
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- Article
Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.
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- Nucleic Acids Research, 2011, v. 39, n. 3, p. 1155, doi. 10.1093/nar/gkq823
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- Article
Thermodynamics of RNA duplexes modified with unlocked nucleic acid nucleotides.
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- Nucleic Acids Research, 2010, v. 38, n. 19, p. 6697, doi. 10.1093/nar/gkq561
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- Article
A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects.
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- Nucleic Acids Research, 2010, v. 38, n. 17, p. 5761, doi. 10.1093/nar/gkq341
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- Article
Improved silencing properties using small internally segmented interfering RNAs.
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- Nucleic Acids Research, 2007, v. 35, n. 17, p. 5886, doi. 10.1093/nar/gkm548
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- Article
Chirality transmission in macromolecular domains.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27708-4
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- Article
Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications.
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- Chemistry & Biodiversity, 2010, v. 7, n. 3, p. 536, doi. 10.1002/cbdv.200900343
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- Article
Synthesis and Biophysical Properties of Oligodeoxynucleotides Containing 2′-Deoxy-5-(4-nitro-1 H-imidazol-1-yl)- β- D-uridine and 2′-Deoxy-5-(1,3-dioxo-1 H-benzo[ de]isoquinolin-2(3 H)-yl)- β- D-uridine Monomers.
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- Chemistry & Biodiversity, 2010, v. 7, n. 2, p. 350, doi. 10.1002/cbdv.200900195
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- Article
Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets.
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- BMC Molecular Biology, 2006, v. 7, p. 19, doi. 10.1186/1471-2199-7-19
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- Article
Analogues of the antibiotic puromycin as potential prodrugs of 3′-amino-3′-deoxythymidine.
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- Journal of Heterocyclic Chemistry, 1992, v. 29, n. 1, p. 5, doi. 10.1002/jhet.5570290102
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- Article
Electrochemistry of Single Metalloprotein and DNA-Based Molecules at Au(111) Electrode Surfaces.
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- ChemPhysChem, 2013, v. 14, n. 10, p. 2101, doi. 10.1002/cphc.201300299
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- Article
Helligkeit durch lokale Rigidifizierung - LNA-verstärkte FIT-Sonden zur bildgebenden Darstellung von Ribonukleotidpartikeln in vivo.
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- Angewandte Chemie, 2014, v. 126, n. 42, p. 11553, doi. 10.1002/ange.201406022
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- Article
A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids.
- Published in:
- Angewandte Chemie, 2013, v. 125, n. 47, p. 12567, doi. 10.1002/ange.201307661
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- Publication type:
- Article
Innentitelbild: A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids (Angew. Chem. 47/2013).
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- Angewandte Chemie, 2013, v. 125, n. 47, p. 12418, doi. 10.1002/ange.201309065
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- Publication type:
- Article
Photoinduzierter reduktiver Elektronentransfer in LNA:DNA-Hybriden: Kompromiss aus Konformation und Basenstapelung.
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- Angewandte Chemie, 2012, v. 124, n. 40, p. 10168, doi. 10.1002/ange.201204901
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- Article
Spectral imaging and nucleic acid mimics fluorescence in situ hybridization (SI-NAM-FISH) for multiplex detection of clinical pathogens.
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- Frontiers in Microbiology, 2022, v. 13, p. 01, doi. 10.3389/fmicb.2022.976639
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- Article
Towards Fluorescence In Vivo Hybridization (FIVH) Detection of H. pylori in Gastric Mucosa Using Advanced LNA Probes.
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- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125494
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- Article
By-Product Formation in Repetitive PCR Amplification of DNA Libraries during SELEX.
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- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114693
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- Article
Hybridization-Based Detection of <i>Helicobacter pylori</i> at Human Body Temperature Using Advanced Locked Nucleic Acid (LNA) Probes.
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- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081230
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- Article
Efficient Reverse Transcription Using Locked Nucleic Acid Nucleotides towards the Evolution of Nuclease Resistant RNA Aptamers.
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- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035990
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- Article
Functionalization of 2"-C-(Piperazinomethyl)-2',3'-BcNA (Bicyclic Nucleic Acids) with Pyren-1-ylcarbonyl Units.
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- Helvetica Chimica Acta, 2014, v. 97, n. 9, p. 1204
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- Article
Oligonucleotides Containing Novel 4′- C- or 3′- C-(Aminoalkyl)-Branched Thymidines.
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- Helvetica Chimica Acta, 2000, v. 83, n. 1, p. 128, doi. 10.1002/(SICI)1522-2675(20000119)83:1<128::AID-HLCA128>3.0.CO;2-Q
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- Article
Evaluation of Gene Expression Knock‐Down by Chemically and Structurally Modified Gapmer Antisense Oligonucleotides.
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- ChemBioChem, 2022, v. 23, n. 15, p. 1, doi. 10.1002/cbic.202200168
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- Article
Development of an Efficient G-Quadruplex-Stabilised Thrombin-Binding Aptamer Containing a Three-Carbon Spacer Molecule.
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- ChemBioChem, 2017, v. 18, n. 8, p. 755, doi. 10.1002/cbic.201600654
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- Article
Unlocked Nucleic Acids with a Pyrene-Modified Uracil: Synthesis, Hybridization Studies, Fluorescent Properties and i-Motif Stability.
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- ChemBioChem, 2014, v. 15, n. 1, p. 146, doi. 10.1002/cbic.201300567
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- Article
Novel (Phenylethynyl)pyrene-LNA Constructs for Fluorescence SNP Sensing in Polymorphic Nucleic Acid Targets.
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- ChemBioChem, 2012, v. 13, n. 10, p. 1509, doi. 10.1002/cbic.201200079
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- Article
Pyrene-Modified Unlocked Nucleic Acids: Synthesis, Thermodynamic Studies, and Fluorescent Properties.
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- ChemBioChem, 2012, v. 13, n. 4, p. 590, doi. 10.1002/cbic.201100689
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- Article
Synthesis and Structural Characterization of 2′-Fluoro-α- L-RNA-Modified Oligonucleotides.
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- ChemBioChem, 2011, v. 12, n. 12, p. 1904, doi. 10.1002/cbic.201100161
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- Article
Minimal Substrate Features for Erm Methyltransferases Defined by Using a Combinatorial Oligonucleotide Library.
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- ChemBioChem, 2011, v. 12, n. 4, p. 610, doi. 10.1002/cbic.201000606
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- Article
Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation.
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- Clinical & Translational Medicine, 2021, v. 11, n. 6, p. 1, doi. 10.1002/ctm2.427
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- Article
Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities.
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- Nucleic Acids Research, 2005, v. 33, n. 13, p. 4223, doi. 10.1093/nar/gki726
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- Article
Transcription factor decoy oligonucleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity.
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- Nucleic Acids Research, 2004, v. 32, n. 6, p. 1874, doi. 10.1093/nar/gkh503
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- Article
Self‐Assembly of DNA–Peptide Supermolecules: Coiled‐Coil Peptide Structures Templated by d‐DNA and l‐DNA Triplexes Exhibit Chirality‐Independent but Orientation‐Dependent Stabilizing Cooperativity.
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- Chemistry - A European Journal, 2020, v. 26, n. 25, p. 5676, doi. 10.1002/chem.201905636
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- Article
Gapmer Antisense Oligonucleotides Containing 2′,3′‐Dideoxy‐2′‐fluoro‐3′‐C‐hydroxymethyl‐β‐d‐lyxofuranosyl Nucleotides Display Site‐Specific RNase H Cleavage and Induce Gene Silencing
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- Chemistry - A European Journal, 2020, v. 26, n. 6, p. 1368, doi. 10.1002/chem.201904540
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- Article