Works by Wen-Cheng Xiong

Results: 97

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia.

Published in:

2008

By:

Lin Mei;
Wen-Cheng Xiong;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

journal article

Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02843-2

By:

Pan, Jin-Xiu;
Sun, Dong;
Lee, Daehoon;
Xiong, Lei;
Ren, Xiao;
Guo, Hao-han;
Yao, Ling-Ling;
Lu, Yuyi;
Jung, Caroline;
Xiong, Wen-Cheng

Publication type:

Article

APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress.

Published in:

Cell Death & Disease, 2018, v. 9, n. 11, p. 1, doi. 10.1038/s41419-018-1123-7

By:

Pan, Jin-Xiu;
Tang, Fulei;
Xiong, Fei;
Xiong, Lei;
Zeng, Peng;
Wang, Bo;
Zhao, Kai;
Guo, Haohan;
Shun, Cui;
Xia, Wen-Fang;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

Article

Neogenin, a regulator of adult hippocampal neurogenesis, prevents depressive-like behavior.

Published in:

Cell Death & Disease, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41419-017-0019-2

By:

Sun, Dong;
Sun, Xiang-Dong;
Zhao, Lu;
Lee, Dae-Hoon;
Hu, Jin-Xia;
Tang, Fu-Lei;
Pan, Jin-Xiu;
Mei, Lin;
Zhu, Xiao-Juan;
Xiong, Wen-Cheng

Publication type:

Article

VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation.

Published in:

Molecular Brain, 2015, v. 8, p. 1, doi. 10.1186/s13041-015-0156-4

By:

Yun Tian;
Fu-Lei Tang;
XiangDong Sun;
Lei Wen;
Lin Mei;
Bei-Sha Tang;
Wen-Cheng Xiong

Publication type:

Article

Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis.

Published in:

Molecular Brain, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-6606-7-10

By:

Wei Liu;
Fu-Lei Tang;
Joanna Erion;
Hang Xiao;
Jian Ye;
Wen-Cheng Xiong

Publication type:

Article

Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse.

Published in:

Frontiers in Molecular Neuroscience, 2016, p. 1, doi. 10.3389/fnmol.2016.00003

By:

Garrett, Andrew M.;
Jucius, Thomas J.;
Sigaud, Liam P. R.;
Fu-Lei Tang;
Wen-Cheng Xiong;
Ackerman, Susan L.;
Burgess, Robert W.

Publication type:

Article

VPS35 or retromer as a potential target for neurodegenerative disorders: barriers to progress.

Published in:

Expert Opinion on Therapeutic Targets, 2024, v. 28, n. 8, p. 701, doi. 10.1080/14728222.2024.2392700

By:

Wu, Anika;
Lee, Daehoon;
Xiong, Wen-Cheng

Publication type:

Article

Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency.

Published in:

PLoS Biology, 2020, v. 18, n. 6, p. 1, doi. 10.1371/journal.pbio.3000731

By:

Xiong, Lei;
Zhao, Kai;
Cao, Yu;
Guo, Hao-Han;
Pan, Jin-Xiu;
Yang, Xiao;
Ren, Xiao;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

Article

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

Published in:

PLoS Biology, 2019, v. 17, n. 10, p. 1, doi. 10.1371/journal.pbio.3000461

By:

Ma, Jun;
Zhang, Lu-Qing;
He, Zi-Xuan;
He, Xiao-Xiao;
Wang, Ya-Jun;
Jian, You-Li;
Wang, Xin;
Zhang, Bin-Bin;
Su, Ce;
Lu, Jun;
Huang, Bai-Qu;
Zhang, Yu;
Wang, Gui-Yun;
Guo, Wei-Xiang;
Qiu, De-Lai;
Mei, Lin;
Xiong, Wen-Cheng;
Zheng, Yao-Wu;
Zhu, Xiao-Juan

Publication type:

Article

Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling.

Published in:

Journal of Cell Biology, 2013, v. 200, n. 6, p. 821, doi. 10.1083/jcb.201207154

By:

Wen-Fang Xia;
Fu-Lei Tang;
Lei Xiong;
Shan Xiong;
Ji-Ung Jung;
Dae-Hoon Lee;
Xing-Sheng Li;
Xu Feng;
Lin Mei;
Wen-Cheng Xiong

Publication type:

Article

VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.

Published in:

Journal of Cell Biology, 2011, v. 195, n. 5, p. 765, doi. 10.1083/jcb.201105109

By:

Lei Wen;
Fu-Lei Tang;
Yan Hong;
Shi-Wen Luo;
Chun-Lei Wang;
Wanxia He;
Chengyong Shen;
Ji-Ung Jung;
Fei Xiong;
Dae-hoon Lee;
Quan-Guang Zhang;
Darrell Brann;
Tae-Wan Kim;
Riqiang Yan;
Lin Mei;
Wen-Cheng Xiong

Publication type:

Article

pHluorin-BACE1-mCherry Acts as a Reporter for the Intracellular Distribution of Active BACE1 In Vitro and In Vivo.

Published in:

Cells (2073-4409), 2019, v. 8, n. 5, p. 474, doi. 10.3390/cells8050474

By:

Zhao, Lu;
Zhao, Yang;
Tang, Fu-Lei;
Xiong, Lei;
Su, Ce;
Mei, Lin;
Zhu, Xiao-Juan;
Xiong, Wen-Cheng

Publication type:

Article

Focal adhesion kinase in netrin-1 signaling.

Published in:

Nature Neuroscience, 2004, v. 7, n. 11, p. 1204, doi. 10.1038/nn1330

By:

Xiu-rong Ren;
Guo-li Ming;
Yi Xie;
Yan Hong;
Dong-mei Sun;
Zhong-qiu Zhao;
Zhu Feng;
Qiang Wang;
Sangwoo Shim;
Zhou-feng Chen;
Hong-jun Song;
Lin Mei;
Wen-cheng Xiong

Publication type:

Article

PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation.

Published in:

Nature Neuroscience, 2001, v. 4, n. 1, p. 19, doi. 10.1038/82858

By:

Yang, Feng;
He, Xiang-ping;
Feng, Linyin;
Mizuno, Keiko;
Liu, Xu-Wen;
Russell, James;
Xiong, Wen-Cheng;
Lu, Bai

Publication type:

Article

Muscular Swedish mutant APP-to-Brain axis in the development of Alzheimer's disease.

Published in:

Cell Death & Disease, 2022, v. 13, n. 11, p. 1, doi. 10.1038/s41419-022-05378-4

By:

Pan, Jin-Xiu;
Lee, Daehoon;
Sun, Dong;
Zhao, Kai;
Xiong, Lei;
Guo, Hao-Han;
Ren, Xiao;
Chen, Peng;
Lopez de Boer, Raquel;
Lu, Yuyi;
Lin, Helena;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

Article

Neogenin as a Receptor for Early Cell Fate Determination in Preimplantation Mouse Embryos.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101989

By:

Lee, Jae Ho;
Choi, Sung Sook;
Kim, Hae Won;
Xiong, Wen Cheng;
Min, Churl K.;
Lee, Sang Jin

Publication type:

Article

Autoantibodies to Agrin in Myasthenia Gravis Patients.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091816

By:

Zhang, Bin;
Shen, Chengyong;
Bealmear, Beverly;
Ragheb, Samia;
Xiong, Wen-Cheng;
Lewis, Richard A.;
Lisak, Robert P.;
Mei, Lin

Publication type:

Article

Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation.

Published in:

FASEB Journal, 2004, v. 18, n. 10, p. 1060, doi. 10.1096/fj.04-1505com

By:

Dougherty, Christopher J.;
Kubasiak, Lori A.;
Frazier, Donna P.;
Huifang Li;
Wen-Cheng Xiong;
Bishopric, Nanette H.;
Webster, Keith A.

Publication type:

Article

Microglial VPS35 deficiency impairs Aβ phagocytosis and Aβ-induced disease-associated microglia, and enhances Aβ associated pathology.

Published in:

2022

By:

Ren, Xiao;
Yao, Lingling;
Wang, YongGang;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

journal article

Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38719-8

By:

Daly, James L.;
Danson, Chris M.;
Lewis, Philip A.;
Zhao, Lu;
Riccardo, Sara;
Di Filippo, Lucio;
Cacchiarelli, Davide;
Lee, Daehoon;
Cross, Stephen J.;
Heesom, Kate J.;
Xiong, Wen-Cheng;
Ballabio, Andrea;
Edgar, James R.;
Cullen, Peter J.

Publication type:

Article

Regulation of Synapse Development by Vgat Deletion from ErbB4-Positive Interneurons.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 10, p. 2533, doi. 10.1523/JNEUROSCI.0669-17.2018

By:

Lin, Thiri W.;
Zhibing Tan;
Arnab Barik;
Dong-Min Yin;
Egil Brudvik;
Hongsheng Wang;
Wen-Cheng Xiong;
Lin Mei

Publication type:

Article

Muscle Yap Is a Regulator of Neuromuscular Junction Formation and Regeneration.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 13, p. 3465, doi. 10.1523/JNEUROSCI.2934-16.2017

By:

Kai Zhao;
Chengyong Shen;
Yisheng Lu;
Zhihui Huang;
Lei Li;
Rand, Christopher D.;
Jinxiu Pan;
Xiang-Dong Sun;
Zhibing Tan;
Hongsheng Wang;
Guanglin Xing;
Yu Cao;
Guoqing Hu;
Jiliang Zhou;
Wen-Cheng Xiong;
Lin Mei

Publication type:

Article

Schwann Cells in Neuromuscular Junction Formation and Maintenance.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 38, p. 9770, doi. 10.1523/JNEUROSCI.0174-16.2016

By:

Barik, Arnab;
Lei Li;
Sathyamurthy, Anupama;
Wen-Cheng Xiong;
Lin Mei

Publication type:

Article

Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 21, p. 5833, doi. 10.1523/JNEUROSCI.4487-15.2016

By:

Zhihui Huang;
Dong Sun;
Jin-Xia Hu;
Fu-Lei Tang;
Dae-Hoon Lee;
Ying Wang;
Guoqing Hu;
Xiao-Juan Zhu;
Jiliang Zhou;
Lin Mei;
Wen-Cheng Xiong

Publication type:

Article

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 29, p. 10613, doi. 10.1523/JNEUROSCI.0042-15.2015

By:

Fu-Lei Tang;
Erion, Joanna R.;
Yun Tian;
Wei Liu;
Dong-Min Yin;
Jian Ye;
Baisha Tang;
Lin Mei;
Wen-Cheng Xiong

Publication type:

Article

LRP4 Is Critical for Neuromuscular Junction Maintenance.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 42, p. 13892, doi. 10.1523/JNEUROSCI.1733-14.2014

By:

Barik, Arnab;
Yisheng Lu;
Sathyamurthy, Anupama;
Bowman, Andrew;
Chengyong Shen;
Lei Li;
Wen-cheng Xiong;
Lin Mei

Publication type:

Article

Genetic Labeling Reveals Novel Cellular Targets of Schizophrenia Susceptibility Gene: Distribution of GABA and Non-GABA ErbB4-Positive Cells in Adult Mouse Brain.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 40, p. 13549, doi. 10.1523/JNEUROSCI.2021-14.2014

By:

Bean, Jonathan C.;
Lin, Thiri W.;
Sathyamurthy, Anupama;
Fang Liu;
Dong-Min Yin;
Wen-Cheng Xiong;
Lin Mei

Publication type:

Article

Regulation of Spine Formation by ErbB4 in PV-Positive Interneurons.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 49, p. 19295, doi. 10.1523/JNEUROSCI.2090-13.2013

By:

Dong-Min Yin;
Xiang-Dong Sun;
Bean, Jonathan C.;
Lin, Thiri W.;
Sathyamurthy, Anupama;
Wen-Cheng Xiong;
Tian-Ming Gao;
Yong-Jun Chen;
Lin Mei

Publication type:

Article

Erbin Is Required for Myelination in Regenerated Axons after Injury.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 43, p. 15169, doi. 10.1523/JNEUROSCI.2466-12.2012

By:

Chuan Liang;
Yanmei Tao;
Chengyong Shen;
Zui Tan;
Wen-Cheng Xiong;
Lin Mei

Publication type:

Article

Antibodies against low-density lipoprotein receptor-related protein 4 induce myasthenia gravis.

Published in:

2013

By:

Shen, Chengyong;
Lu, Yisheng;
Zhang, Bin;
Figueiredo, Dwight;
Bean, Jonathan;
Jung, Jiung;
Wu, Haitao;
Barik, Arnab;
Yin, Dong-Min;
Xiong, Wen-Cheng;
Mei, Lin

Publication type:

journal article

Antibodies against low-density lipoprotein receptor--related protein 4 induce myasthenia gravis.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 12, p. 5190, doi. 10.1172/JCI66039

By:

Chengyong Shen;
Yisheng Lu;
Bin Zhang;
Figueiredo, Dwight;
Jonathan Bean;
Jiung Jung;
Haitao Wu;
Arnab Barik;
Dong-Min Yin;
Wen-Cheng Xiong;
Lin Mei

Publication type:

Article

Ephrin-B3 recruits PSD-95 to synapses.

Published in:

Nature Neuroscience, 2015, v. 18, n. 11, p. 1535, doi. 10.1038/nn.4147

By:

Fei, Erkang;
Xiong, Wen-Cheng;
Mei, Lin

Publication type:

Article

Corrigendum: Erbin interacts with TARP γ-2 for surface expression of AMPA receptors in cortical interneurons.

Published in:

Nature Neuroscience, 2013, v. 16, n. 12, p. 1908, doi. 10.1038/nn1213-1908d

By:

Tao, Yanmei;
Chen, Yong-Jun;
Shen, Chengyong;
Luo, Zhengyi;
Bates, C Ryan;
Lee, Daehoon;
Marchetto, Sylvie;
Gao, Tian-Ming;
Borg, Jean-Paul;
Xiong, Wen-Cheng;
Mei, Lin

Publication type:

Article

Adolescent dopamine slows spine maturation.

Published in:

Nature Neuroscience, 2013, v. 16, n. 11, p. 1514, doi. 10.1038/nn.3558

By:

Yin, Dong-Min;
Xiong, Wen-Cheng;
Mei, Lin

Publication type:

Article

Erbin interacts with TARP γ-2 for surface expression of AMPA receptors in cortical interneurons.

Published in:

Nature Neuroscience, 2013, v. 16, n. 3, p. 290, doi. 10.1038/nn.3320

By:

Tao, Yanmei;
Chen, Yong-Jun;
Shen, Chengyong;
Luo, Zhengyi;
Bates, C Ryan;
Lee, Daehoon;
Marchetto, Sylvie;
Gao, Tian-Ming;
Borg, Jean-Paul;
Xiong, Wen-Cheng;
Mei, Lin

Publication type:

Article

Retrograde regulation of motoneuron differentiation by muscle β-catenin.

Published in:

Nature Neuroscience, 2008, v. 11, n. 3, p. 262, doi. 10.1038/nn2053

By:

Xiao-Ming Li;
Xian-Ping Dong;
Shi-Wen Luo;
Bin Zhang;
Dae-Hoon Lee;
Ting, Annie K. L.;
Neiswender, Hannah;
Chang-Hoon Kim;
Carpenter-Hyland, Ezekiel;
Tian-Ming Gao;
Wen-Cheng Xiong;
Lin Mei

Publication type:

Article

Vps35-deficiency impairs SLC4A11 trafficking and promotes corneal dystrophy.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184906

By:

Liu, Wei;
Tang, Fu-Lei;
Lin, Sen;
Zhao, Kai;
Mei, Lin;
Ye, Jian;
Xiong, Wen-Cheng

Publication type:

Article

Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179047

By:

Sun, Dong;
Zhou, Xue;
Yu, Hua-Li;
He, Xiao-Xiao;
Guo, Wei-Xiang;
Xiong, Wen-Cheng;
Zhu, Xiao-Juan

Publication type:

Article

Cover Image, Volume 533, Issue 3.

Published in:

Journal of Comparative Neurology, 2025, v. 533, n. 3, p. 1, doi. 10.1002/cne.70037

By:

Shen, Chen;
Cui, Wanpeng;
Xiong, Wen‐Cheng;
Mei, Lin

Publication type:

Article

Heterogeneity of Layer 1 Interneurons in the Mouse Medial Prefrontal Cortex.

Published in:

Journal of Comparative Neurology, 2025, v. 533, n. 3, p. 1, doi. 10.1002/cne.70030

By:

Shen, Chen;
Cui, Wanpeng;
Xiong, Wen‐Cheng;
Mei, Lin

Publication type:

Article

Osteoclastic ATP6AP2 maintains β-catenin levels to prevent hyper-osteoclastic activation and trabecular bone-loss.

Published in:

Journal of Bone & Mineral Research, 2024, v. 39, n. 12, p. 1821, doi. 10.1093/jbmr/zjae164

By:

Chen, Li;
Xiong, Lei;
Guo, Haohan;
Feng, Xu;
Zhu, Xiaojuan;
Xiong, Wen-Cheng

Publication type:

Article

Agrin and LRP4 antibodies as new biomarkers of myasthenia gravis.

Published in:

Annals of the New York Academy of Sciences, 2018, v. 1413, n. 1, p. 126, doi. 10.1111/nyas.13573

By:

Yan, Min;
Xing, Guang‐Lin;
Xiong, Wen‐Cheng;
Mei, Lin

Publication type:

Article

Musk signaling at the neuromuscular junction.

Published in:

Journal of Molecular Neuroscience, 2006, v. 30, n. 1/2, p. 223, doi. 10.1385/JMN:30:1:223

By:

Wang, Qiang;
Zhang, Bin;
Xiong, Wen-Cheng;
Mei, Lin

Publication type:

Article

Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss.

Published in:

Bone Research, 2021, v. 9, n. 1, p. 1, doi. 10.1038/s41413-021-00146-0

By:

Guo, Hao-Han;
Xiong, Lei;
Pan, Jin-Xiu;
Lee, Daehoon;
Liu, Kevin;
Ren, Xiao;
Wang, Bo;
Yang, Xiao;
Cui, Shun;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

Article

YAP Is a Critical Inducer of SOCS3, Preventing Reactive Astrogliosis.

Published in:

Cerebral Cortex, 2016, v. 26, n. 5, p. 2299, doi. 10.1093/cercor/bhv292

By:

Zhihui Huang;
Ying Wang;
Guoqing Hu;
Jiliang Zhou;
Lin Mei;
Wen-Cheng Xiong

Publication type:

Article

Parkinson's in the bone.

Published in:

Cell & Bioscience, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13578-021-00702-5

By:

Xiong, Lei;
Pan, Jin-Xiu;
Guo, Hao-han;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

Article

Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation.

Published in:

Journal of Molecular Cell Biology, 2020, v. 12, n. 1, p. 17, doi. 10.1093/jmcb/mjz076

By:

Lin, Sen;
Liu, Wei;
Chen, Chun-Lin;
Sun, Dong;
Hu, Jin-Xia;
Li, Lei;
Ye, Jian;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

Article

Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast‐Lineage Cells.

Published in:

Journal of Bone & Mineral Research, 2019, v. 34, n. 5, p. 939, doi. 10.1002/jbmr.3667

By:

Wang, Bo;
Pan, Jin‐Xiu;
Yu, Huali;
Xiong, Lei;
Zhao, Kai;
Xiong, Shan;
Guo, Jun‐Peng;
Lin, Sen;
Sun, Dong;
Zhao, Lu;
Guo, Haohan;
Mei, Lin;
Xiong, Wen‐Cheng

Publication type:

Article

Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine.

Published in:

Journal of Bone & Mineral Research, 2013, v. 28, n. 10, p. 2122, doi. 10.1002/jbmr.1954

By:

Xia, Wen-Fang;
Jung, Ji-Ung;
Shun, Cui;
Xiong, Shan;
Xiong, Lei;
Shi, Xing-Ming;
Mei, Lin;
Xiong, Wen-Cheng

Publication type:

Article