Works by Weissman, Jonathan

Results: 90

Release of both native and non-native proteins from a cis-only GroEL ternary complex.

Published in:

Nature, 1996, v. 383, n. 6595, p. 96, doi. 10.1038/383096a0

By:

Burston, Steven G.;
Weissman, Jonathan S.

Publication type:

Article

Efficient catalysis of disulphide bond rearrangements by protein disulphide isomerase.

Published in:

Nature, 1993, v. 365, n. 6442, p. 185, doi. 10.1038/365185a0

By:

Weissman, Jonathan S.;
Kim, Peter S.

Publication type:

Article

Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41788-4

By:

Sunshine, Sara;
Puschnik, Andreas S.;
Replogle, Joseph M.;
Laurie, Matthew T.;
Liu, Jamin;
Zha, Beth Shoshana;
Nuñez, James K.;
Byrum, Janie R.;
McMorrow, Aidan H.;
Frieman, Matthew B.;
Winkler, Juliane;
Qiu, Xiaojie;
Rosenberg, Oren S.;
Leonetti, Manuel D.;
Ye, Chun Jimmie;
Weissman, Jonathan S.;
DeRisi, Joseph L.;
Hein, Marco Y.

Publication type:

Article

Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure.

Published in:

Genome Biology, 2013, v. 14, n. 9, p. 1, doi. 10.1186/gb-2013-14-9-r97

By:

Muzzey, Dale;
Schwartz, Katja;
Weissman, Jonathan S.;
Sherlock, Gavin

Publication type:

Article

Enclosed chambers for humidity control and sample containment in fiber diffraction.

Published in:

Journal of Applied Crystallography, 2008, v. 41, n. 1, p. 206, doi. 10.1107/S0021889807060803

By:

McDonald, Michele;
Kendall, Amy;
Tanaka, Motomasa;
Weissman, Jonathan S.;
Stubbs, Gerald

Publication type:

Article

Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation.

Published in:

Molecular Systems Biology, 2014, v. 10, n. 12, p. 1, doi. 10.15252/msb.20145524

By:

Pop, Cristina;
Rouskin, Silvi;
Ingolia, Nicholas T;
Han, Lu;
Phizicky, Eric M;
Weissman, Jonathan S;
Koller, Daphne

Publication type:

Article

Automated identification of pathways from quantitative genetic interaction data.

Published in:

Molecular Systems Biology, 2010, v. 6, n. 1, p. 1, doi. 10.1038/msb.2010.27

By:

Battle, Alexis;
Jonikas, Martin C;
Walter, Peter;
Weissman, Jonathan S;
Koller, Daphne

Publication type:

Article

A general lack of compensation for gene dosage in yeast.

Published in:

Molecular Systems Biology, 2010, v. 6, n. 1, p. 1, doi. 10.1038/msb.2010.19

By:

Springer, Michael;
Weissman, Jonathan S;
Kirschner, Marc W

Publication type:

Article

Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss.

Published in:

Molecular Systems Biology, 2007, v. 3, n. 1, p. 86, doi. 10.1038/msb4100127

By:

Ihmels, Jan;
Collins, Sean R;
Schuldiner, Maya;
Krogan, Nevan J;
Weissman, Jonathan S

Publication type:

Article

Cellular response to small molecules that selectively stall protein synthesis by the ribosome.

Published in:

PLoS Genetics, 2019, v. 15, n. 3, p. 1, doi. 10.1371/journal.pgen.1008057

By:

Liaud, Nadège;
Horlbeck, Max A.;
Gilbert, Luke A.;
Gjoni, Ketrin;
Weissman, Jonathan S.;
Cate, Jamie H. D.

Publication type:

Article

Strain conformation, primary structure and the propagation of the yeast prion [PSI<sup>+</sup>].

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 493, doi. 10.1038/nsmb.2030

By:

Verges, Katherine J.;
Smith, Melanie H.;
Toyama, Brandon H.;
Weissman, Jonathan S.

Publication type:

Article

Oxidative protein folding in eukaryotes: mechanisms and consequences.

Published in:

Journal of Cell Biology, 2004, v. 164, n. 3, p. 341, doi. 10.1083/jcb.200311055

By:

Tu, Benjamin P.;
Weissman, Jonathan S.

Publication type:

Article

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.69142

By:

Coukos, Robert;
Yao, David;
Sanchez, Mateo I.;
Strand, Eric T.;
Olive, Meagan E.;
Udeshi, Namrata D.;
Weissman, Jonathan S.;
Carr, Steven A.;
Bassik, Michael C.;
Ting, Alice Y.

Publication type:

Article

Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.67624

By:

Le Vasseur, Maxence;
Friedman, Jonathan;
Jost, Marco;
Jiawei Xu;
Yamada, Justin;
Kampmann, Martin;
Horlbeck, Max A.;
Salemi, Michelle R.;
Phinney, Brett S.;
Weissman, Jonathan S.;
Nunnari, Jodi

Publication type:

Article

CRISPR-based functional genomics in human dendritic cells.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65856

By:

Jost, Marco;
Jacobson, Amy N.;
Hussmann, Jeffrey A.;
Cirolia, Giana;
Fischbach, Michael A.;
Weissman, Jonathan S.

Publication type:

Article

A Luminal Surveillance Complex that Selects Misfolded Glycoproteins for ER Associated Degradation.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A153

By:

Weissman, Jonathan

Publication type:

Article

Proto-genes and de novo gene birth.

Published in:

Nature, 2012, v. 487, n. 7407, p. 370, doi. 10.1038/nature11184

By:

Carvunis, Anne-Ruxandra;
Rolland, Thomas;
Wapinski, Ilan;
Calderwood, Michael A.;
Yildirim, Muhammed A.;
Simonis, Nicolas;
Charloteaux, Benoit;
Hidalgo, César A.;
Barbette, Justin;
Santhanam, Balaji;
Brar, Gloria A.;
Weissman, Jonathan S.;
Regev, Aviv;
Thierry-Mieg, Nicolas;
Cusick, Michael E.;
Vidal, Marc

Publication type:

Article

The translational landscape of mTOR signalling steers cancer initiation and metastasis.

Published in:

Nature, 2012, v. 485, n. 7396, p. 55, doi. 10.1038/nature10912

By:

Hsieh, Andrew C.;
Liu, Yi;
Edlind, Merritt P.;
Ingolia, Nicholas T.;
Janes, Matthew R.;
Sher, Annie;
Shi, Evan Y.;
Stumpf, Craig R.;
Christensen, Carly;
Bonham, Michael J.;
Wang, Shunyou;
Ren, Pingda;
Martin, Michael;
Jessen, Katti;
Feldman, Morris E.;
Weissman, Jonathan S.;
Shokat, Kevan M.;
Rommel, Christian;
Ruggero, Davide

Publication type:

Article

Genetics: Noise rules.

Published in:

Nature, 2011, v. 480, n. 7376, p. 188, doi. 10.1038/480188a

By:

El-Samad, Hana;
Weissman, Jonathan S.

Publication type:

Article

Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats.

Published in:

Nature, 2011, v. 476, n. 7358, p. 88, doi. 10.1038/nature10245

By:

Gracheva, Elena O.;
Cordero-Morales, Julio F.;
González-Carcacía, José A.;
Ingolia, Nicholas T.;
Manno, Carlo;
Aranguren, Carla I.;
Weissman, Jonathan S.;
Julius, David

Publication type:

Article

Nascent transcript sequencing visualizes transcription at nucleotide resolution.

Published in:

Nature, 2011, v. 469, n. 7330, p. 368, doi. 10.1038/nature09652

By:

Churchman, L. Stirling;
Weissman, Jonathan S.

Publication type:

Article

Mammalian microRNAs predominantly act to decrease target mRNA levels.

Published in:

Nature, 2010, v. 466, n. 7308, p. 835, doi. 10.1038/nature09267

By:

Huili Guo;
Ingolia, Nicholas T.;
Weissman, Jonathan S.;
Bartel, David P.

Publication type:

Article

Molecular basis of infrared detection by snakes.

Published in:

Nature, 2010, v. 464, n. 7291, p. 1006, doi. 10.1038/nature08943

By:

Gracheva, Elena O.;
Ingolia, Nicholas T.;
Kelly, Yvonne M.;
Cordero-Morales, Julio F.;
Hollopeter, Gunther;
Chesler, Alexander T.;
Sánchez, Elda E.;
Perez, John C.;
Weissman, Jonathan S.;
Julius, David

Publication type:

Article

Orm family proteins mediate sphingolipid homeostasis.

Published in:

Nature, 2010, v. 463, n. 7284, p. 1048, doi. 10.1038/nature08787

By:

Breslow, David K.;
Collins, Sean R.;
Bodenmiller, Bernd;
Aebersold, Ruedi;
Simons, Kai;
Shevchenko, Andrej;
Ejsing, Christer S.;
Weissman, Jonathan S.

Publication type:

Article

Journal club.

Published in:

Nature, 2009, v. 461, n. 7268, p. 1177, doi. 10.1038/4611177e

By:

Weissman, Jonathan

Publication type:

Article

Ribosome profiling reveals the what, when, where and how of protein synthesis.

Published in:

Nature Reviews Molecular Cell Biology, 2015, v. 16, n. 11, p. 651, doi. 10.1038/nrm4069

By:

Brar, Gloria A.;
Weissman, Jonathan S.

Publication type:

Article

Single-cell analysis of long non-coding RNAs in the developing human neocortex.

Published in:

Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-0932-1

By:

Liu, Siyuan John;
Nowakowski, Tomasz J.;
Pollen, Alex A.;
Lui, Jan H.;
Horlbeck, Max A.;
Attenello, Frank J.;
He, Daniel;
Weissman, Jonathan S.;
Kriegstein, Arnold R.;
Diaz, Aaron A.;
Lim, Daniel A.

Publication type:

Article

Corrigendum: Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps.

Published in:

Nature Protocols, 2015, v. 10, n. 4, p. 643, doi. 10.1038/nprot.2014.103

By:

Kampmann, Martin;
Bassik, Michael C;
Weissman, Jonathan S

Publication type:

Article

Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps.

Published in:

Nature Protocols, 2014, v. 9, n. 8, p. 1825, doi. 10.1038/nprot.2014.103

By:

Kampmann, Martin;
Bassik, Michael C;
Weissman, Jonathan S

Publication type:

Article

Mechanism of Prion Propagation: Amyloid Growth Occurs by Monomer Addition.

Published in:

PLoS Biology, 2004, v. 2, n. 10, p. 1582, doi. 10.1371/journal.pbio.0020321

By:

Collins, Sean R.;
Douglass, Adam;
Vale, Ronald D.;
Weissman, Jonathan S.

Publication type:

Article

Mechanism of Prion Propagation: Amyloid Growth Occurs by Monomer Addition.

Published in:

PLoS Biology, 2004, v. 2, n. 9, p. 1, doi. 10.1371/journal.pbio.0020321

By:

Collins, Sean R;
Douglass, Adam;
Vale, Ronald D;
Weissman, Jonathan S

Publication type:

Article

Dissection and Design of Yeast Prions.

Published in:

PLoS Biology, 2004, v. 2, n. 4, p. 442, doi. 10.1371/journal.pbio.0020086

By:

Osherovich, Lev Z.;
Cox, Brian S.;
Tuite, Mick F.;
Weissman, Jonathan S.

Publication type:

Article

Dissection and Design of Yeast Prions.

Published in:

PLoS Biology, 2004, v. 2, n. 3, p. 1, doi. 10.1371/journal.pbio.0020086

By:

Osherovich, Lev Z;
Cox, Brian S;
Tuite, Mick F;
Weissman, Jonathan S

Publication type:

Article

Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo.

Published in:

Nature, 2014, v. 505, n. 7485, p. 701, doi. 10.1038/nature12894

By:

Rouskin, Silvi;
Zubradt, Meghan;
Washietl, Stefan;
Kellis, Manolis;
Weissman, Jonathan S.

Publication type:

Article

A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens.

Published in:

BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09754-y

By:

Guna, Alina;
Page, Katharine R.;
Replogle, Joseph M.;
Esantsi, Theodore K.;
Wang, Maxine L.;
Weissman, Jonathan S.;
Voorhees, Rebecca M.

Publication type:

Article

rRNA:mRNA pairing alters the length and the symmetry of mRNA-protected fragments in ribosome profiling experiments.

Published in:

Bioinformatics, 2013, v. 29, n. 12, p. 1488, doi. 10.1093/bioinformatics/btt184

By:

O’Connor, Patrick B. F.;
Li, Gene-Wei;
Weissman, Jonathan S.;
Atkins, John F.;
Baranov, Pavel V.

Publication type:

Article

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria.

Published in:

Journal of Cell Biology, 2011, v. 195, n. 2, p. 323, doi. 10.1083/jcb.201107053

By:

Hoppins, Suzanne;
Collins, Sean R.;
Cassidy-Stone, Ann;
Hummel, Eric;
DeVay, Rachel M.;
Lackner, Laura L.;
Westermann, Benedikt;
Schuldiner, Maya;
Weissman, Jonathan S.;
Nunnari, Jodi

Publication type:

Article

Regulated Ire 1-dependent decay of messenger RNAs in mammalian cells.

Published in:

Journal of Cell Biology, 2009, v. 186, n. 3, p. 323, doi. 10.1083/jcb.200903014

By:

Hollien, Julie;
Lin, Jonathan H.;
Li, Han;
Stevens, Nicole;
Walter, Peter;
Weissman, Jonathan S.

Publication type:

Article

Maximizing CRISPRi efficacy and accessibility with dual- sgRNA libraries and optimal effectors.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.81856

By:

Replogle, Joseph M.;
Bonnar, Jessica L.;
Pogson, Angela N.;
Liem, Christina R.;
Maier, Nolan K.;
Yufang Ding;
Russell, Baylee J.;
Xingren Wang;
Kun Leng;
Guna, Alina;
Norman, Thomas M.;
Pak, Ryan A.;
Ramos, Daniel M.;
Ward, Michael E.;
Gilbert, Luke A.;
Kampmann, Martin;
Weissman, Jonathan S.;
Jost, Marco

Publication type:

Article

Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning.

Published in:

2023

By:

Koblan, Luke W.;
Arbab, Mandana;
Shen, Max W.;
Hussmann, Jeffrey A.;
Anzalone, Andrew V.;
Doman, Jordan L.;
Newby, Gregory A.;
Yang, Dian;
Mok, Beverly;
Replogle, Joseph M.;
Xu, Albert;
Sisley, Tyler A.;
Weissman, Jonathan S.;
Adamson, Britt;
Liu, David R.

Publication type:

Correction Notice

Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.

Published in:

Nature Biotechnology, 2022, v. 40, n. 12, p. 1834, doi. 10.1038/s41587-022-01386-z

By:

Tolani, Bhairavi;
Celli, Anna;
Yao, Yanmin;
Tan, Yong Zi;
Fetter, Richard;
Liem, Christina R.;
de Smith, Adam J.;
Vasanthakumar, Thamiya;
Bisignano, Paola;
Cotton, Adam D.;
Seiple, Ian B.;
Rubinstein, John L.;
Jost, Marco;
Weissman, Jonathan S.

Publication type:

Article

Variant to function mapping at single-cell resolution through network propagation.

Published in:

Nature Biotechnology, 2022, v. 40, n. 11, p. 1644, doi. 10.1038/s41587-022-01341-y

By:

Yu, Fulong;
Cato, Liam D.;
Weng, Chen;
Liggett, L. Alexander;
Jeon, Soyoung;
Xu, Keren;
Chiang, Charleston W. K.;
Wiemels, Joseph L.;
Weissman, Jonathan S.;
de Smith, Adam J.;
Sankaran, Vijay G.

Publication type:

Article

Functional single-cell genomics of human cytomegalovirus infection.

Published in:

Nature Biotechnology, 2022, v. 40, n. 3, p. 391, doi. 10.1038/s41587-021-01059-3

By:

Hein, Marco Y.;
Weissman, Jonathan S.

Publication type:

Article

Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning.

Published in:

Nature Biotechnology, 2021, v. 39, n. 11, p. 1414, doi. 10.1038/s41587-021-00938-z

By:

Koblan, Luke W.;
Arbab, Mandana;
Shen, Max W.;
Hussmann, Jeffrey A.;
Anzalone, Andrew V.;
Doman, Jordan L.;
Newby, Gregory A.;
Yang, Dian;
Mok, Beverly;
Replogle, Joseph M.;
Xu, Albert;
Sisley, Tyler A.;
Weissman, Jonathan S.;
Adamson, Britt;
Liu, David R.

Publication type:

Article

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.

Published in:

Nature Biotechnology, 2020, v. 38, n. 8, p. 954, doi. 10.1038/s41587-020-0470-y

By:

Replogle, Joseph M.;
Norman, Thomas M.;
Xu, Albert;
Hussmann, Jeffrey A.;
Chen, Jin;
Cogan, J. Zachery;
Meer, Elliott J.;
Terry, Jessica M.;
Riordan, Daniel P.;
Srinivas, Niranjan;
Fiddes, Ian T.;
Arthur, Joseph G.;
Alvarado, Luigi J.;
Pfeiffer, Katherine A.;
Mikkelsen, Tarjei S.;
Weissman, Jonathan S.;
Adamson, Britt

Publication type:

Article

Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes.

Published in:

2020

By:

Horlbeck, Max A.;
Liu, S. John;
Chang, Howard Y.;
Lim, Daniel A.;
Weissman, Jonathan S.

Publication type:

Letter

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs.

Published in:

Nature Biotechnology, 2020, v. 38, n. 3, p. 355, doi. 10.1038/s41587-019-0387-5

By:

Jost, Marco;
Santos, Daniel A.;
Saunders, Reuben A.;
Horlbeck, Max A.;
Hawkins, John S.;
Scaria, Sonia M.;
Norman, Thomas M.;
Hussmann, Jeffrey A.;
Liem, Christina R.;
Gross, Carol A.;
Weissman, Jonathan S.

Publication type:

Article

Conformational diversity in a yeast prion dictates its seeding specificity.

Published in:

Nature, 2001, v. 410, n. 6825, p. 223, doi. 10.1038/35065632

By:

Chien, Peter;
Weissman, Jonathan S.

Publication type:

Article

New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells.

Published in:

Journal of Cell Biology, 2019, v. 218, n. 11, p. 3861, doi. 10.1083/jcb.201902028

By:

Bassaganyas, Laia;
Popa, Stephanie J.;
Horlbeck, Max;
Puri, Claudia;
Stewart, Sarah E.;
Campelo, Felix;
Ashok, Anupama;
Butnaru, Cristian M.;
Brouwers, Nathalie;
Heydari, Kartoosh;
Ripoche, Jean;
Weissman, Jonathan;
Rubinsztein, David C.;
Schekman, Randy;
Malhotra, Vivek;
Moreau, Kevin;
Villeneuve, Julien

Publication type:

Article

Cycloheximide can distort measurements of mRNA levels and translation efficiency.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 10, p. 4974, doi. 10.1093/nar/gkz205

By:

Santos, Daniel A;
Shi, Lei;
Tu, Benjamin P;
Weissman, Jonathan S

Publication type:

Article