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Correlation of the inability to sustain growth in defined serum-free medium with the suppression of tumorigenicity in Wilms' nephroblastoma.
Published in:
Journal of Cellular Physiology, 1991, v. 147, n. 2, p. 248, doi. 10.1002/jcp.1041470209
By:
- Dowdy, Steven F.;
- Weissman, Bernard E.;
- Stanbridge, Eric J.
Publication type:
Article
A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.
Published in:
Journal of Pathology, 2020, v. 252, n. 2, p. 125, doi. 10.1002/path.5504
By:
- Bowman, Brittany M;
- Montgomery, Stephanie A;
- Schrank, Travis P;
- Simon, Jeremy M;
- Ptacek, Travis S;
- Tamir, Tigist Y;
- Mulvaney, Kathleen M;
- Weir, Seth J;
- Nguyen, Tuong T;
- Murphy, Ryan M;
- Makowski, Liza;
- Hayes, D Neil;
- Chen, Xiaoxin L;
- Randell, Scott H;
- Weissman, Bernard E;
- Major, Michael B
Publication type:
Article
The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.
Published in:
Journal of Pathology, 2017, v. 242, n. 3, p. 371, doi. 10.1002/path.4912
By:
- Wang, Yemin;
- Chen, Shary Yuting;
- Karnezis, Anthony N;
- Colborne, Shane;
- Santos, Nancy Dos;
- Lang, Jessica D;
- Hendricks, William PD;
- Orlando, Krystal A;
- Yap, Damian;
- Kommoss, Friedrich;
- Bally, Marcel B;
- Morin, Gregg B;
- Trent, Jeffrey M;
- Weissman, Bernard E;
- Huntsman, David G
Publication type:
Article
Dual loss of the SWI/ SNF complex ATPases SMARCA4/ BRG1 and SMARCA2/ BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.
Published in:
Journal of Pathology, 2016, v. 238, n. 3, p. 389, doi. 10.1002/path.4633
By:
- Karnezis, Anthony N;
- Wang, Yemin;
- Ramos, Pilar;
- Hendricks, William PD;
- Oliva, Esther;
- D'Angelo, Emanuela;
- Prat, Jaime;
- Nucci, Marisa R;
- Nielsen, Torsten O;
- Chow, Christine;
- Leung, Samuel;
- Kommoss, Friedrich;
- Kommoss, Stefan;
- Silva, Annacarolina;
- Ronnett, Brigitte M;
- Rabban, Joseph T;
- Bowtell, David D;
- Weissman, Bernard E;
- Trent, Jeffrey M;
- Gilks, C Blake
Publication type:
Article
WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene.
Published in:
EMBO Journal, 1999, v. 18, n. 14, p. 3990, doi. 10.1093/emboj/18.14.3990
By:
- Mayo, Marty W.;
- Cun-Yu Wang;
- Drouin, S. Scott;
- Madrid, Lee V.;
- Marshall, Allen F.;
- Reed, John C.;
- Weissman, Bernard E.;
- Baldwin, Albert S.
Publication type:
Article
Identification of Two 36-kD Phosphoproteins Associated with Altered Differentiation in Retrovirus-Transformed Balb/MK-2 Mouse Keratinocytes.
Published in:
Pathobiology, 1991, v. 59, n. 6, p. 384, doi. 10.1159/000163682
By:
- Makino, Jayne K.;
- Weissman, Bernard E.
Publication type:
Article
BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.
Published in:
Nucleic Acids Research, 2010, v. 38, n. 20, p. 6906, doi. 10.1093/nar/gkq559
By:
- Cohen, Stephanie M.;
- Chastain, Paul D.;
- Rosson, Gary B.;
- Groh, Beezly S.;
- Weissman, Bernard E.;
- Kaufman, David G.;
- Bultman, Scott J.
Publication type:
Article
SWI/SNF chromatin remodeling complexes and cancer.
Published in:
American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, 2014, v. 166C, n. 3, p. 350, doi. 10.1002/ajmg.c.31410
By:
- Biegel, Jaclyn A.;
- Busse, Tracy M.;
- Weissman, Bernard E.
Publication type:
Article
ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas.
Published in:
PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0297741
By:
- Nguyen, Vinh;
- Schrank, Travis P.;
- Major, Michael B.;
- Weissman, Bernard E.
Publication type:
Article
Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression.
Published in:
Oncogene, 2002, v. 21, n. 8, p. 1196, doi. 10.1038/sj.onc.1205188
By:
- Reisman, David N.;
- Strobeck, Matthew W.;
- Betz, Bryan L.;
- Sciariotta, Janiece;
- Funkhouser Jr., William;
- Murchardt, Christian;
- Yaniv, Moshe;
- Sherman, Larry S.;
- Knudsen, Erik S.;
- Weissman, Bernard E.
Publication type:
Article
Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2 and c-Myc expression.
Published in:
Oncogene, 2001, v. 20, n. 25, p. 3258, doi. 10.1038/sj.onc.1204437
By:
- Dauphinot, Luce;
- De Oliveira, Catherine;
- Melot, Thomas;
- Sevenet, Nicolas;
- Thomas, Venetia;
- Weissman, Bernard E;
- Delattre, Olivier
Publication type:
Article
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
Published in:
Oncogene, 1999, v. 18, n. 52, p. 7559, doi. 10.1038/sj.onc.1203168
By:
- DeCristofaro, Marc F;
- Betz, Bryan L;
- Wang, Weidong;
- Weissman, Bernard E
Publication type:
Article
Failure of HPV E6 to rapidly degrade p53 in human HeLa×PNET cell hybrids.
Published in:
Oncogene, 1997, v. 14, n. 14, p. 1669, doi. 10.1038/sj.onc.1201001
By:
- Isaacs, Jennifer S;
- Chen, Pengchin;
- Garza, Armandina;
- Hansen, Marc F;
- Barrett, J Carl;
- Weissman, Bernard E
Publication type:
Article
A human melanoma metastasis-suppressor locus maps to 6q16.3-q23.
Published in:
International Journal of Cancer, 2000, v. 86, n. 4, p. 524, doi. 10.1002/(SICI)1097-0215(20000515)86:4<524::AID-IJC13>3.0.CO;2-W
By:
- Miele, Mary E.;
- Jewett, Matthew D.;
- Goldberg, Steven F.;
- Hyatt, David L.;
- Morelli, Christina;
- Gualandi, Francesca;
- Rimessi, Paola;
- Hicks, Deana J.;
- Weissman, Bernard E.;
- Barbanti-Brodano, Giuseppi;
- Welch, Danny R.
Publication type:
Article
Inactivation of SNF5 cooperates with p53 loss to accelerate tumor formation in Snf5+/−; p53+/− mice.
Published in:
Molecular Carcinogenesis, 2009, v. 48, n. 12, p. 1139, doi. 10.1002/mc.20568
By:
- DelBove, Jessica;
- Kuwahara, Yasumichi;
- Mora-Blanco, E. Lorena;
- Godfrey, Virginia;
- Funkhouser, William K.;
- Fletcher, Christopher D.M.;
- Van Dyke, Terry;
- Roberts, Charles W.M.;
- Weissman, Bernard E.
Publication type:
Article
Analysis of oncogene, tumor suppressor gene, and chromosomal alterations in HeLa × osteosarcoma somatic cell hybrids.
Published in:
Molecular Carcinogenesis, 1999, v. 25, n. 1, p. 30, doi. 10.1002/(SICI)1098-2744(199905)25:1<30::AID-MC4>3.0.CO;2-N
By:
- Isfort, Robert J.;
- Cody, David B.;
- Lovell, Glenda J.;
- Gioeli, Daniel;
- Weissman, Bernard E.;
- Doersen, Claus-Jens
Publication type:
Article
Interference of proteins involved in the cytoplasmic sequestration of p53 with human papillomavirus E6-mediated degradation.
Published in:
Molecular Carcinogenesis, 1999, v. 24, n. 1, p. 70, doi. 10.1002/(SICI)1098-2744(199901)24:1<70::AID-MC10>3.0.CO;2-5
By:
- Isaacs, Jennifer S.;
- Barrett, J. Carl;
- Weissman, Bernard E.
Publication type:
Article
Correlation between reduction of metastasis in the MDA-MB-435 model system and increased expression of the Kai-1 protein.
Published in:
Molecular Carcinogenesis, 1998, v. 21, n. 2, p. 111, doi. 10.1002/(SICI)1098-2744(199802)21:2<111::AID-MC5>3.0.CO;2-Q
By:
- Phillips, Karen K.;
- White, Alicia E.;
- Hicks, Deana J.;
- Welch, Danny R.;
- Barrett, J. Carl;
- Wei, Lisa L.;
- Weissman, Bernard E.
Publication type:
Article
Localization of a putative liver tumor suppressor locus to a 950-kb region of human 11p11.2-p12 using rat liver tumor microcell hybrid cell lines.
Published in:
Molecular Carcinogenesis, 1997, v. 19, n. 4, p. 267, doi. 10.1002/(SICI)1098-2744(199708)19:4<267::AID-MC8>3.0.CO;2-9
By:
- Coleman, William B.;
- Esch, Gwyn L.;
- Borchert, Kristen M.;
- McCullough, Karen D.;
- Reid, Laura H.;
- Weissman, Bernard E.;
- Smith, Gary J.;
- Grisham, Joe W.
Publication type:
Article
Suppression of the tumorigenic phenotype of a rat liver epithelial tumor cell line by the p11.2-p12 region of human chromosome 11.
Published in:
Molecular Carcinogenesis, 1995, v. 13, n. 4, p. 220, doi. 10.1002/mc.2940130405
By:
- Coleman, William B.;
- McCullough, Karen D.;
- Esch, Gwyn L.;
- Civalier, Chris J.;
- Livanos, Elizabeth;
- Weissman, Bernard E.;
- Grisham, Joe W.;
- Smith, Gary J.
Publication type:
Article
Activation of ras oncogenes in chemically transformed BALB/MK-2 mouse keratinocytes.
Published in:
Molecular Carcinogenesis, 1989, v. 2, n. 3, p. 150, doi. 10.1002/mc.2940020308
By:
- Weissman, Bernard E.;
- Arboleda, Marie J.;
- Kimoto, Kathleen A.;
- Macdonald, Marsha J.;
- Ochiai, Ruth;
- Der, Channing J.
Publication type:
Article
Establishment and characterization of MRT cell lines from genetically engineered mouse models and the influence of genetic background on their development.
Published in:
International Journal of Cancer, 2013, v. 132, n. 12, p. 2767, doi. 10.1002/ijc.27976
By:
- Kuwahara, Yasumichi;
- Mora‐Blanco, E. Lorena;
- Banine, Fatima;
- Rogers, Arlin B.;
- Fletcher, Christopher;
- Sherman, Larry S.;
- Roberts, Charles W. M.;
- Weissman, Bernard E.
Publication type:
Article
BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest.
Published in:
Journal of Cellular Physiology, 2011, v. 226, n. 8, p. 1989, doi. 10.1002/jcp.22533
By:
- Bartlett, Christopher;
- Orvis, Tess J.;
- Rosson, Gary S.;
- Weissman, Bernard E.
Publication type:
Article
Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
Published in:
Journal of Cellular Physiology, 2003, v. 194, n. 3, p. 289, doi. 10.1002/jcp.10202
By:
- Hummer, B. Timothy;
- Bartlett, Christopher;
- Henry, Erin;
- Weissman, Bernard E.
Publication type:
Article
Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies.
Published in:
Journal of Cellular Physiology, 2001, v. 186, n. 1, p. 136, doi. 10.1002/1097-4652(200101)186:1<136::AID-JCP1010>3.0.CO;2-4
By:
- Cristofaro, Marc F. D;
- Betz, Bryan L.;
- Rorie, Checo J.;
- Reisman, David N.;
- Wang, Weidong;
- Weissman, Bernard E.
Publication type:
Article
Identification of additional complementation groups that regulate genomic instability.
Published in:
Genes, Chromosomes & Cancer, 1997, v. 20, n. 2, p. 103, doi. 10.1002/(SICI)1098-2264(199710)20:2<103::AID-GCC1>3.0.CO;2-7
By:
- Hall, Ingrid J.;
- Gioeli, Dan;
- Weissman, Bernard E.;
- Tlsty, Thea D.
Publication type:
Article
Localization of a Tumor Suppressor Gene in 11p15.5 Using the G401 Wilms' Tumor Assay.
Published in:
Human Molecular Genetics, 1996, v. 5, n. 2, p. 239, doi. 10.1093/hmg/5.2.239
By:
- Reid, Laura Hink;
- West, Ande;
- Gioeli, Daniel G.;
- Phillips, Karen K.;
- Kelleher, Kevin F.;
- Araujo, Diana;
- Stanbridge, Eric J.;
- Dowdy, Steven F.;
- Gerhard, Daniela S.;
- Weissman, Bernard E.
Publication type:
Article

Found: 27

Correlation of the inability to sustain growth in defined serum-free medium with the suppression of tumorigenicity in Wilms' nephroblastoma.

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

Dual loss of the SWI/ SNF complex ATPases SMARCA4/ BRG1 and SMARCA2/ BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene.

Identification of Two 36-kD Phosphoproteins Associated with Altered Differentiation in Retrovirus-Transformed Balb/MK-2 Mouse Keratinocytes.

BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.

SWI/SNF chromatin remodeling complexes and cancer.

ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas.

Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression.

Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57<sup>KIP2</sup> and c-Myc expression.

Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.

Failure of HPV E6 to rapidly degrade p53 in human HeLa×PNET cell hybrids.

A human melanoma metastasis-suppressor locus maps to 6q16.3-q23.

Inactivation of SNF5 cooperates with p53 loss to accelerate tumor formation in Snf5<sup>+/−</sup>; p53<sup>+/−</sup> mice.

Analysis of oncogene, tumor suppressor gene, and chromosomal alterations in HeLa × osteosarcoma somatic cell hybrids.

Interference of proteins involved in the cytoplasmic sequestration of p53 with human papillomavirus E6-mediated degradation.

Correlation between reduction of metastasis in the MDA-MB-435 model system and increased expression of the Kai-1 protein.

Localization of a putative liver tumor suppressor locus to a 950-kb region of human 11p11.2-p12 using rat liver tumor microcell hybrid cell lines.

Suppression of the tumorigenic phenotype of a rat liver epithelial tumor cell line by the p11.2-p12 region of human chromosome 11.

Activation of ras oncogenes in chemically transformed BALB/MK-2 mouse keratinocytes.

Establishment and characterization of MRT cell lines from genetically engineered mouse models and the influence of genetic background on their development.

BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest.

Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.

Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies.

Identification of additional complementation groups that regulate genomic instability.

Localization of a Tumor Suppressor Gene in 11p15.5 Using the G401 Wilms' Tumor Assay.