Found: 18

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  • Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.

    Published in:
    eLife, 2017, p. 1, doi. 10.7554/eLife.23268
    By:
    • Paolella, Brenton R.;
    • Gibson, William J.;
    • Urbanski, Laura M.;
    • Alberta, John A.;
    • Zack, Travis I.;
    • Bandopadhayay, Pratiti;
    • Nichols, Caitlin A.;
    • Agarwalla, Pankaj K.;
    • Brown, Meredith S.;
    • Lamothe, Rebecca;
    • Yong Yu;
    • Choi, Peter S.;
    • Obeng, Esther A.;
    • Heckl, Dirk;
    • Guo Wei;
    • Wang, Belinda;
    • Tsherniak, Aviad;
    • Vazquez, Francisca;
    • Weir, Barbara A.;
    • Root, David E.
    Publication type:
    Article

  • Characterizing genomic alterations in cancer by complementary functional associations.

    Published in:
    Nature Biotechnology, 2016, v. 34, n. 5, p. 539, doi. 10.1038/nbt.3527
    By:
    • Kim, Jong Wook;
    • Botvinnik, Olga B;
    • Abudayyeh, Omar;
    • Birger, Chet;
    • Rosenbluh, Joseph;
    • Shrestha, Yashaswi;
    • Abazeed, Mohamed E;
    • Hammerman, Peter S;
    • DiCara, Daniel;
    • Konieczkowski, David J;
    • Johannessen, Cory M;
    • Liberzon, Arthur;
    • Alizad-Rahvar, Amir Reza;
    • Alexe, Gabriela;
    • Aguirre, Andrew;
    • Ghandi, Mahmoud;
    • Greulich, Heidi;
    • Vazquez, Francisca;
    • Weir, Barbara A;
    • Van Allen, Eliezer M
    Publication type:
    Article

  • High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines.

    Published in:
    Nature Biotechnology, 2016, v. 34, n. 4, p. 419, doi. 10.1038/nbt.3460
    By:
    • Yu, Channing;
    • Mannan, Aristotle M;
    • Yvone, Griselda Metta;
    • Ross, Kenneth N;
    • Zhang, Yan-Ling;
    • Marton, Melissa A;
    • Taylor, Bradley R;
    • Crenshaw, Andrew;
    • Gould, Joshua Z;
    • Tamayo, Pablo;
    • Weir, Barbara A;
    • Tsherniak, Aviad;
    • Wong, Bang;
    • Garraway, Levi A;
    • Shamji, Alykhan F;
    • Palmer, Michelle A;
    • Foley, Michael A;
    • Winckler, Wendy;
    • Schreiber, Stuart L;
    • Kung, Andrew L
    Publication type:
    Article

  • Absolute quantification of somatic DNA alterations in human cancer.

    Published in:
    Nature Biotechnology, 2012, v. 30, n. 5, p. 413, doi. 10.1038/nbt.2203
    By:
    • Carter, Scott L;
    • Cibulskis, Kristian;
    • Helman, Elena;
    • McKenna, Aaron;
    • Shen, Hui;
    • Zack, Travis;
    • Laird, Peter W;
    • Onofrio, Robert C;
    • Winckler, Wendy;
    • Weir, Barbara A;
    • Beroukhim, Rameen;
    • Pellman, David;
    • Levine, Douglas A;
    • Lander, Eric S;
    • Meyerson, Matthew;
    • Getz, Gad
    Publication type:
    Article

  • Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.

    Published in:
    Nature Medicine, 2008, v. 14, n. 8, p. 822, doi. 10.1038/nm.1790
    By:
    • Shedden, Kerby;
    • Taylor, Jeremy M. G.;
    • Enkemann, Steven A.;
    • Ming-Sound Tsao;
    • Yeatman, Timothy J.;
    • Gerald, William L.;
    • Eschrich, Steven;
    • Jurisica, Igor;
    • Giordano, Thomas J.;
    • Misek, David E.;
    • Chang, Andrew C.;
    • Chang Qi Zhu;
    • Strumpf, Daniel;
    • Hanash, Samir;
    • Shepherd, Frances A.;
    • Ding, Keyue;
    • Seymour, Lesley;
    • Naoki, Katsuhiko;
    • Pennell, Nathan;
    • Weir, Barbara
    Publication type:
    Article

  • Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

    Published in:
    Nature Genetics, 2010, v. 42, n. 8, p. 715, doi. 10.1038/ng.619
    By:
    • Barretina, Jordi;
    • Taylor, Barry S.;
    • Banerji, Shantanu;
    • Ramos, Alexis H.;
    • Lagos-Quintana, Mariana;
    • DeCarolis, Penelope L.;
    • Shah, Kinjal;
    • Socci, Nicholas D.;
    • Weir, Barbara A.;
    • Ho, Alan;
    • Chiang, Derek Y.;
    • Reva, Boris;
    • Mermel, Craig H.;
    • Getz, Gad;
    • Antipin, Yevgenyi;
    • Beroukhim, Rameen;
    • Major, John E.;
    • Hatton, Charles;
    • Nicoletti, Richard;
    • Hanna, Megan
    Publication type:
    Article

  • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.

    Published in:
    Nature Genetics, 2009, v. 41, n. 11, p. 1238, doi. 10.1038/ng.465
    By:
    • Bass, Adam J.;
    • Watanabe, Hideo;
    • Mermel, Craig H.;
    • Soyoung Yu;
    • Perner, Sven;
    • Verhaak, Roel G.;
    • So Young Kim;
    • Wardwell, Leslie;
    • Tamayo, Pablo;
    • Gat-Viks, Irit;
    • Ramos, Alex H.;
    • Woo, Michele S.;
    • Weir, Barbara A.;
    • Getz, Gad;
    • Beroukhim, Rameen;
    • O'Kelly, Michael;
    • Dutt, Amit;
    • Rozenblatt-Rosen, Orit;
    • Dziunycz, Piotr;
    • Komisarof, Justin
    Publication type:
    Article

  • Insulins of hystricomorph rodents.

    Published in:
    1973
    By:
    • Neville, R. W. J.;
    • Weir, Barbara J.;
    • Lazarus, Norman R.;
    • Neville, R W;
    • Weir, B J;
    • Lazarus, N R
    Publication type:
    journal article

  • Major copy proportion analysis of tumor samples using SNP arrays.

    Published in:
    BMC Bioinformatics, 2008, v. 9, p. 1, doi. 10.1186/1471-2105-9-204
    By:
    • Cheng Li;
    • Beroukhim, Rameen;
    • Weir, Barbara A.;
    • Winckler, Wendy;
    • Garraway, Levi A.;
    • Sellers, William R.;
    • Meyerson, Matthew
    Publication type:
    Article

  • The landscape of somatic copy-number alteration across human cancers.

    Published in:
    Nature, 2010, v. 463, n. 7283, p. 899, doi. 10.1038/nature08822
    By:
    • Beroukhim, Rameen;
    • Mermel, Craig H.;
    • Porter, Dale;
    • Wei, Guo;
    • Raychaudhuri, Soumya;
    • Donovan, Jerry;
    • Barretina, Jordi;
    • Boehm, Jesse S.;
    • Dobson, Jennifer;
    • Urashima, Mitsuyoshi;
    • Mc Henry, Kevin T.;
    • Pinchback, Reid M.;
    • Ligon, Azra H.;
    • Cho, Yoon-Jae;
    • Haery, Leila;
    • Greulich, Heidi;
    • Reich, Michael;
    • Winckler, Wendy;
    • Lawrence, Michael S.;
    • Weir, Barbara A.
    Publication type:
    Article

  • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.

    Published in:
    Nature, 2009, v. 462, n. 7269, p. 108, doi. 10.1038/nature08460
    By:
    • Barbie, David A.;
    • Tamayo, Pablo;
    • Boehm, Jesse S.;
    • Kim, So Young;
    • Moody, Susan E.;
    • Dunn, Ian F.;
    • Schinzel, Anna C.;
    • Sandy, Peter;
    • Meylan, Etienne;
    • Scholl, Claudia;
    • Fröhling, Stefan;
    • Chan, Edmond M.;
    • Sos, Martin L.;
    • Michel, Kathrin;
    • Mermel, Craig;
    • Silver, Serena J.;
    • Weir, Barbara A.;
    • Reiling, Jan H.;
    • Sheng, Qing;
    • Gupta, Piyush B.
    Publication type:
    Article

  • Characterizing the cancer genome in lung adenocarcinoma.

    Published in:
    Nature, 2007, v. 450, n. 7171, p. 893, doi. 10.1038/nature06358
    By:
    • Weir, Barbara A.;
    • Woo, Michele S.;
    • Getz, Gad;
    • Perner, Sven;
    • Li Ding;
    • Beroukhim, Rameen;
    • Lin, William M.;
    • Province, Michael A.;
    • Kraja, Aldi;
    • Johnson, Laura A.;
    • Shah, Kinjal;
    • Sato, Mitsuo;
    • Thomas, Roman K.;
    • Barletta, Justine A.;
    • Borecki, Ingrid B.;
    • Broderick, Stephen;
    • Chang, Andrew C.;
    • Chiang, Derek Y.;
    • Chirieac, Lucian R.;
    • Jeonghee Cho
    Publication type:
    Article

  • Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma.

    Published in:
    Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 8b, p. 1977, doi. 10.1111/j.1582-4934.2008.00594.x
    By:
    • Barletta, Justine A.;
    • Perner, Sven;
    • Iafrate, A. John;
    • Yeap, Beow Y.;
    • Weir, Barbara A.;
    • Johnson, Laura A.;
    • Johnson, Bruce E.;
    • Meyerson, Matthew;
    • Rubin, Mark A.;
    • Travis, William D.;
    • Loda, Massimo;
    • Chirieac, Lucian R.
    Publication type:
    Article

  • Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis.

    Published in:
    PLoS Computational Biology, 2005, v. 1, n. 6, p. 507, doi. 10.1371/journal.pcbi.0010065
    By:
    • LaFramboise, Thomas;
    • Weir, Barbara A.;
    • Zhao, Xiaojun;
    • Beroukhim, Rameen;
    • Li, Cheng;
    • Harrington, David;
    • Sellers, William R.;
    • Meyerson, Matthew;
    • Bryant, Barbara
    Publication type:
    Article

  • CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.

    Published in:
    2018
    By:
    • Liying Chen;
    • Alexe, Gabriela;
    • Dharia, Neekesh V.;
    • Ross, Linda;
    • Iniguez, Amanda Balboni;
    • Conway, Amy Saur;
    • Emily Jue Wang;
    • Veschi, Veronica;
    • Lam, Norris;
    • Jun Qi;
    • Gustafson, W. Clay;
    • Nasholm, Nicole;
    • Vazquez, Francisca;
    • Weir, Barbara A.;
    • Cowley, Glenn S.;
    • Ali, Levi D.;
    • Pantel, Sasha;
    • Guozhi Jiang;
    • Harrington, William F.;
    • Yenarae Lee
    Publication type:
    journal article

  • Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4.

    Published in:
    Science Translational Medicine, 2012, v. 4, n. 147, p. 1, doi. 10.1126/scitranslmed.3003778
    By:
    • Yin Ren;
    • Hiu Wing Cheung;
    • von Maltzhan, Geoffrey;
    • Agrawal, Amit;
    • Cowley, Glenn S.;
    • Weir, Barbara A.;
    • Boehm, Jesse S.;
    • Tamayo, Pablo;
    • Karst, Alison M.;
    • Liu, Joyce F.;
    • Hirsch, Michelle S.;
    • Mesirov, Jill P.;
    • Drapkin, Ronny;
    • Root, David E.;
    • Lo, Justin;
    • Fogal, Valentina;
    • Ruoslahti, Erkki;
    • Hahn, William C.;
    • Bhatia, Sangeeta N.
    Publication type:
    Article

  • Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway.

    Published in:
    PLoS Genetics, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.pgen.1002772
    By:
    • Lovejoy, Courtney A.;
    • Li, Wendi;
    • Reisenweber, Steven;
    • Thongthip, Supawat;
    • Bruno, Joanne;
    • De Lange, Titia;
    • De, Saurav;
    • Petrini, John H. J.;
    • Sung, Patricia A.;
    • Jasin, Maria;
    • Rosenbluh, Joseph;
    • Zwang, Yaara;
    • Weir, Barbara A.;
    • Hatton, Charlie;
    • Ivanova, Elena;
    • Macconaill, Laura;
    • Hanna, Megan;
    • Hahn, William C.;
    • Lue, Neal F.;
    • Reddel, Roger R.
    Publication type:
    Article

  • The methyltransferase domain of DNMT1 is an essential domain in acute myeloid leukemia independent of DNMT3A mutation.

    Published in:
    Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04139-5
    By:
    • Bhogal, Balpreet;
    • Weir, Barbara A.;
    • Crescenzo, Ramona;
    • Marien, Ann;
    • Kwon, Min Chul;
    • Philippar, Ulrike;
    • Cowley, Glenn S.
    Publication type:
    Article