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Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5×FAD Mice.
- Published in:
- Molecular Neurobiology, 2024, v. 61, n. 6, p. 3343, doi. 10.1007/s12035-023-03791-0
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- Article
Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline.
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- Journal of Neurochemistry, 2024, v. 168, n. 5, p. 801, doi. 10.1111/jnc.15900
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- Article
Transcriptomic and proteomic characterization of the locus coeruleus in a rat model of Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075403
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- Article
Consequences of Pathogenic Tau Expression in Mouse Locus Coeruleus.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079429
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- Article
Consequences of neuromelanin‐like pigmentation on locus coeruleus integrity and function in mice.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072199
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- Article
Consequences of neuromelanin‐like pigmentation on locus coeruleus integrity and function in mice.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072199
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- Article
Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 5, p. 2182, doi. 10.1002/alz.12937
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- Article
The Neurotoxin DSP-4 Dysregulates the Locus Coeruleus-Norepinephrine System and Recapitulates Molecular and Behavioral Aspects of Prodromal Neurodegenerative Disease.
- Published in:
- eNeuro, 2023, v. 10, n. 1, p. 1, doi. 10.1523/ENEURO.0483-22.2022
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- Article
The effects of locus coeruleus stimulation on the BOLD global signal in TgF344‐AD rats.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.061608
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- Article
Effects of optogenetic locus coeurleus stimulation on functional connectivity in a rat model of Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.063368
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- Article
Chemical ablation of locus coeruleus terminals in mice dysregulates behavioral features reminiscent of prodromal Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.063331
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- Article
Metabolic effects of the schizophrenia-associated 3q29 deletion.
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- Translational Psychiatry, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41398-022-01824-1
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- Article
Altered locus coeruleus activity and neurochemistry in the presence of Alzheimer's disease‐like hyperphosphorylated tau pathology.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054367
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- Article
RGS14 modulates locomotor behavior and ERK signaling induced by environmental novelty and cocaine within discrete limbic structures.
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- Psychopharmacology, 2021, v. 238, n. 10, p. 2755, doi. 10.1007/s00213-021-05892-x
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- Article
Cell-type specific expression and behavioral impact of galanin and GalR1 in the locus coeruleus during opioid withdrawal.
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- 2021
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- journal article
Cover Image.
- Published in:
- Addiction Biology, 2021, v. 26, n. 5, p. 1, doi. 10.1111/adb.13095
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- Article
ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease.
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- Acta Neuropathologica, 2021, v. 142, n. 1, p. 139, doi. 10.1007/s00401-021-02315-1
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- Article
Regulator of G‐protein signaling 14 (RGS14) alters hippocampal pathology following excitotoxic injury due to status epilepticus.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02632
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- Article
The behavioral effects of virally induced human tau expression in the locus coeruleus of TgF344‐AD rats: Molecular and cell biology/tau.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038175
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- Article
Loss of β‐arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids.
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- Addiction Biology, 2020, v. 25, n. 6, p. 1, doi. 10.1111/adb.12823
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- Article
Noradrenergic circuits in the forebrain control affective responses to novelty.
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- Psychopharmacology, 2020, v. 237, n. 11, p. 3337, doi. 10.1007/s00213-020-05615-8
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- Article
What's That (Blue) Spot on my MRI? Multimodal Neuroimaging of the Locus Coeruleus in Neurodegenerative Disease.
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- Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.583421
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- Article
Chronic Environmental or Genetic Elevation of Galanin in Noradrenergic Neurons Confers Stress Resilience in Mice.
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- Journal of Neuroscience, 2020, v. 40, n. 39, p. 7464, doi. 10.1523/JNEUROSCI.0973-20.2020
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- Article
Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease.
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- Journal of Neuroscience, 2020, v. 40, n. 39, p. 7559, doi. 10.1523/JNEUROSCI.1468-19.2020
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- Publication type:
- Article
Central norepinephrine transmission is required for stress-induced repetitive behavior in two rodent models of obsessive-compulsive disorder.
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- Psychopharmacology, 2020, v. 237, n. 7, p. 1973, doi. 10.1007/s00213-020-05512-0
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- Article
Vesicular monoamine transporter 2 mediates fear behavior in mice.
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- Genes, Brain & Behavior, 2020, v. 19, n. 5, p. 1, doi. 10.1111/gbb.12634
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- Article
A galactose‐1‐phosphate uridylyltransferase‐null rat model of classic galactosemia mimics relevant patient outcomes and reveals tissue‐specific and longitudinal differences in galactose metabolism.
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- Journal of Inherited Metabolic Disease, 2020, v. 43, n. 3, p. 518, doi. 10.1002/jimd.12205
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- Article
Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviors.
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- Brain Structure & Function, 2020, v. 225, n. 2, p. 785, doi. 10.1007/s00429-020-02035-4
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- Article
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
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- 2020
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- Publication type:
- journal article
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
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- Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 422, doi. 10.1172/JCI130513
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- Article
O4‐11‐05: A PROOF OF CONCEPT PHASE II STUDY REPURPOSING ATOMOXETINE FOR NEUROPROTECTION IN MILD COGNITIVE IMPAIRMENT: EVIDENCE FOR TARGET ENGAGEMENT, REGULATION OF CSF BIOMARKERS, AND DISEASE‐MODIFYING POTENTIAL.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1263, doi. 10.1016/j.jalz.2019.06.4804
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- Article
F4‐07‐04: THE CONSEQUENCES OF TAU IN THE LOCUS COERULEUS ON ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1394, doi. 10.1016/j.jalz.2018.06.2891
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- Article
Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.
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- Journal of Neuroscience, 2018, v. 38, n. 1, p. 74, doi. 10.1523/JNEUROSCI.1483-17.2017
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- Article
Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels.
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- Psychopharmacology, 2018, v. 235, n. 1, p. 23, doi. 10.1007/s00213-017-4744-0
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- Article
Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease.
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- 2017
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- Publication type:
- journal article
LSD1 protects against hippocampal and cortical neurodegeneration.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00922-9
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- Article
Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus.
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- Neural Plasticity, 2017, p. 1, doi. 10.1155/2017/7829507
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- Article
Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.
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- Journal of Neuroscience Research, 2017, v. 95, n. 5, p. 1144, doi. 10.1002/jnr.23970
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- Article
ELUCIDATING THE RELATIONSHIP BETWEEN HYPERPHOSPHORYLATED TAU AND LOCUS COERULEUS DEGENERATION IN ALZHEIMER’S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P844, doi. 10.1016/j.jalz.2016.06.1727
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- Article
Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice.
- Published in:
- PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0154864
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- Publication type:
- Article
Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens.
- Published in:
- 2016
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- Publication type:
- journal article
A new knock-in mouse model of l-DOPA-responsive dystonia.
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- 2015
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- Publication type:
- journal article
Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 19, p. 5512, doi. 10.1093/hmg/ddv282
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- Publication type:
- Article
The galanin receptor agonist, galnon, attenuates cocaine-induced reinstatement and dopamine overflow in the frontal cortex.
- Published in:
- Addiction Biology, 2015, v. 20, n. 4, p. 701, doi. 10.1111/adb.12166
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- Publication type:
- Article
The effects of post-extinction exercise on cocaine-primed and stress-induced reinstatement of cocaine seeking in rats.
- Published in:
- Psychopharmacology, 2015, v. 232, n. 8, p. 1395, doi. 10.1007/s00213-014-3778-9
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- Publication type:
- Article
Norepinephrine Is Necessary for Experience-Dependent Plasticity in the Developing Mouse Auditory Cortex.
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- Journal of Neuroscience, 2015, v. 35, n. 6, p. 2432, doi. 10.1523/JNEUROSCI.0532-14.2015
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- Article
Ear2 Deletion Causes Early Memory and Learning Deficits in APP/PS1 Mice.
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- Journal of Neuroscience, 2014, v. 34, n. 26, p. 8845, doi. 10.1523/JNEUROSCI.4027-13.2014
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- Article
The Role of the Neurokinin-1 Receptor in Stress-Induced Reinstatement of Alcohol and Cocaine Seeking.
- Published in:
- Neuropsychopharmacology, 2014, v. 39, n. 5, p. 1093, doi. 10.1038/npp.2013.309
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- Article
7,8-Dihydroxyflavone Prevents Synaptic Loss and Memory Deficits in a Mouse Model of Alzheimer's Disease.
- Published in:
- Neuropsychopharmacology, 2014, v. 39, n. 3, p. 638, doi. 10.1038/npp.2013.243
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- Publication type:
- Article
Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice.
- Published in:
- Psychopharmacology, 2013, v. 228, n. 2, p. 263, doi. 10.1007/s00213-013-3034-8
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- Article