Works matching AU Weedon, Michael N.

Results: 136

HLA haplotype diversity, islet autoantibody status and discriminative ability of type 1 diabetes genetic risk score in Indians.

Published in:

Diabetic Medicine, 2025, v. 42, n. 8, p. 1, doi. 10.1111/dme.70041

By:

Sankareswaran, Alagu;
Kunte, Pooja;
Fraser, Diane P.;
Shaik, Mobeen;
Lavanuru, Dimple;
Weedon, Michael N.;
Oram, Richard A.;
Yajnik, Chittaranjan S.;
Chandak, Giriraj R.

Publication type:

Article

Genome-wide association analysis of composite sleep health scores in 413,904 individuals.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07514-0

By:

Goodman, Matthew O.;
Faquih, Tariq;
Paz, Valentina;
Nagarajan, Pavithra;
Lane, Jacqueline M.;
Spitzer, Brian;
Maher, Matthew;
Chung, Joon;
Cade, Brian E.;
Purcell, Shaun M.;
Zhu, Xiaofeng;
Noordam, Raymond;
Phillips, Andrew J. K.;
Kyle, Simon D.;
Spiegelhalder, Kai;
Weedon, Michael N.;
Lawlor, Deborah A.;
Rotter, Jerome I.;
Taylor, Kent D.;
Isasi, Carmen R.

Publication type:

Article

An Interleukin-18 Polymorphism Is Associated With Reduced Serum Concentrations and Better Physical Functioning in Older People.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 1, p. 73, doi. 10.1093/gerona/62.1.73

By:

Frayling, Timothy M.;
Rafiq, Sajjad;
Murray, Anna;
Hurst, Alison J.;
Weedon, Michael N.;
Henley, William;
Bandinelli, Stefania;
Corsi, Anna-Maria;
Ferrucci, Luigi;
Guralnik, Jack M.;
Wallace, Robert B.;
Melzer, David

Publication type:

Article

Type 1 diabetes genetic risk score variation across ancestries using whole genome sequencing and array-based approaches.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-82278-x

By:

Arni, Ankit M.;
Fraser, Diane P.;
Sharp, Seth A.;
Oram, Richard A.;
Johnson, Matthew B.;
Weedon, Michael N.;
Patel, Kashyap A.

Publication type:

Article

A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care.

Published in:

Alimentary Pharmacology & Therapeutics, 2020, v. 52, n. 7, p. 1165, doi. 10.1111/apt.15826

By:

Sharp, Seth A.;
Jones, Samuel E.;
Kimmitt, Robert A.;
Weedon, Michael N.;
Halpin, Anne M.;
Wood, Andrew R.;
Beaumont, Robin N.;
King, Seema;
Heel, David A.;
Campbell, Patricia M.;
Hagopian, William A.;
Turner, Justine M.;
Oram, Richard A

Publication type:

Article

Estimating disease prevalence in large datasets using genetic risk scores.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26501-7

By:

Evans, Benjamin D.;
Słowiński, Piotr;
Hattersley, Andrew T.;
Jones, Samuel E.;
Sharp, Seth;
Kimmitt, Robert A.;
Weedon, Michael N.;
Oram, Richard A.;
Tsaneva-Atanasova, Krasimira;
Thomas, Nicholas J.

Publication type:

Article

3. A Novel, Inexpensive Test Can Discriminate between Type 1 and Type 2 Diabetes (1745-P).

Published in:

Nederlands Tijdschrift voor Diabetologie (NTvD), 2015, v. 13, n. 3, p. 57, doi. 10.1007/s12467-015-0024-y

By:

Oram, Richard A.;
Hill, Anita;
Mcdonald, Timothy J.;
Patel, Kashyap A.;
Jones, Angus G.;
Hattersley, Andrew T.;
Weedon, Michael N.

Publication type:

Article

Methods for quick, accurate and cost-effective determination of the type 1 diabetes genetic risk score (T1D-GRS).

Published in:

Clinical Chemistry & Laboratory Medicine, 2020, v. 58, n. 4, p. e102, doi. 10.1515/cclm-2019-0787

By:

Locke, Jonathan M.;
Latten, Mark J.;
Datta, Renu Y.;
Wood, Andrew R.;
Crockard, Martin A.;
Lamont, John V.;
Weedon, Michael N.;
Oram, Richard A.

Publication type:

Article

Genomic inflation factors under polygenic inheritance.

Published in:

European Journal of Human Genetics, 2011, v. 19, n. 7, p. 807, doi. 10.1038/ejhg.2011.39

By:

Yang, Jian;
Weedon, Michael N.;
Purcell, Shaun;
Lettre, Guillaume;
Estrada, Karol;
Willer, Cristen J.;
Smith, Albert V.;
Ingelsson, Erik;
O'Connell, Jeffrey R.;
Mangino, Massimo;
Mägi, Reedik;
Madden, Pamela A.;
Heath, Andrew C.;
Nyholt, Dale R.;
Martin, Nicholas G.;
Montgomery, Grant W.;
Frayling, Timothy M.;
Hirschhorn, Joel N.;
McCarthy, Mark I.;
Goddard, Michael E.

Publication type:

Article

Predicting human height by Victorian and genomic methods.

Published in:

European Journal of Human Genetics, 2009, v. 17, n. 8, p. 1070, doi. 10.1038/ejhg.2009.5

By:

Aulchenko, Yurii S.;
Struchalin, Maksim V.;
Belonogova, Nadezhda M.;
Axenovich, Tatiana I.;
Weedon, Michael N.;
Hofman, Albert;
Uitterlinden, Andre G.;
Kayser, Manfred;
Oostra, Ben A.;
van Duijn, Cornelia M.;
Janssens, A. Cecile J. W.;
Borodin, Pavel M.

Publication type:

Article

Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.

Published in:

European Journal of Human Genetics, 2007, v. 15, n. 6, p. 679, doi. 10.1038/sj.ejhg.5201802

By:

Barber, Thomas M.;
Bennett, Amanda J.;
Gloyn, Anna L.;
Groves, Christopher J.;
Sovio, Ulla;
Ruokonen, Aimo;
Martikainen, Hannu;
Pouta, Anneli;
Taponen, Saara;
Weedon, Michael N.;
Hartikainen, Anna-Liisa;
Wass, John A. H.;
Järvelin, Marjo-Riitta;
Zeggini, Eleftheria;
Franks, Stephen;
McCarthy, Mark I.

Publication type:

Article

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits.

Published in:

Nature Genetics, 2012, v. 44, n. 4, p. 369, doi. 10.1038/ng.2213

By:

Yang, Jian;
Ferreira, Teresa;
Morris, Andrew P;
Medland, Sarah E;
Madden, Pamela A F;
Heath, Andrew C;
Martin, Nicholas G;
Montgomery, Grant W;
Weedon, Michael N;
Loos, Ruth J;
Frayling, Timothy M;
McCarthy, Mark I;
Hirschhorn, Joel N;
Goddard, Michael E;
Visscher, Peter M

Publication type:

Article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Published in:

2011

By:

Heid, Iris M;
Jackson, Anne U;
Randall, Joshua C;
Winkler, Thomas W;
Qi, Lu;
Steinthorsdottir, Valgerdur;
Thorleifsson, Gudmar;
Zillikens, M Carola;
Speliotes, Elizabeth K;
Mägi, Reedik;
Workalemahu, Tsegaselassie;
White, Charles C;
Bouatia-Naji, Nabila;
Harris, Tamara B;
Berndt, Sonja I;
Ingelsson, Erik;
Willer, Cristen J;
Weedon, Michael N;
Luan, Jian'an;
Vedantam, Sailaja

Publication type:

Correction Notice

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Published in:

Nature Genetics, 2010, v. 42, n. 11, p. 937, doi. 10.1038/ng.686

By:

Speliotes, Elizabeth K.;
Willer, Cristen J.;
Berndt, Sonja I.;
Monda, Keri L.;
Thorleifsson, Gudmar;
Jackson, Anne U.;
Allen, Hana Lango;
Lindgren, Cecilia M.;
Luan, Jian'an;
Mägi, Reedik;
Randall, Joshua C.;
Vedantam, Sailaja;
Winkler, Thomas W.;
Lu Qi;
Workalemahu, Tsegaselassie;
Heid, Iris M.;
Steinthorsdottir, Valgerdur;
Stringham, Heather M.;
Weedon, Michael N.;
Wheeler, Eleanor

Publication type:

Article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Published in:

Nature Genetics, 2010, v. 42, n. 11, p. 949, doi. 10.1038/ng.685

By:

Heid, Iris M.;
Jackson, Anne U.;
Randall, Joshua C.;
Winkler, Thomas W.;
Lu Qi;
Steinthorsdottir, Valgerdur;
Thorleifsson, Gudmar;
Zillikens, M. Carola;
Speliotes, Elizabeth K.;
Mägi, Reedik;
Workalemahu, Tsegaselassie;
White, Charles C.;
Bouatia-Naji, Nabila;
Harris, Tamara B.;
Berndt, Sonja I.;
Ingelsson, Erik;
Willer, Cristen J.;
Weedon, Michael N.;
Luan, Jian'an;
Vedantam, Sailaja

Publication type:

Article

Genome-wide association analysis identifies 20 loci that influence adult height.

Published in:

Nature Genetics, 2008, v. 40, n. 5, p. 575, doi. 10.1038/ng.121

By:

Weedon, Michael N.;
Lango, Hana;
Lindgren, Cecilia M.;
Wallace, Chris;
Evans, David M.;
Mangino, Massimo;
Freathy, Rachel M.;
Perry, John R. B.;
Stevens, Suzanne;
Hall, Alistair S.;
Samani, Nilesh J.;
Shields, Beverly;
Prokopenko, Inga;
Farrall, Martin;
Dominiczak, Anna;
Johnson, Toby;
Bergmann, Sven;
Beckmann, Jacques S.;
Vollenweider, Peter;
Waterworth, Dawn M.

Publication type:

Article

A common variant of HMGA2 is associated with adult and childhood height in the general population.

Published in:

Nature Genetics, 2007, v. 39, n. 10, p. 1245, doi. 10.1038/ng2121

By:

Weedon, Michael N.;
Lettre, Guillaume;
Freathy, Rachel M.;
Lindgren, Cecilia M.;
Voight, Benjamin F.;
Perry, John R. B.;
Elliott, Katherine S.;
Hackett, Rachel;
Guiducci, Candace;
Shields, Beverley;
Zeggini, Eleftheria;
Lango, Hana;
Lyssenko, Valeriya;
Timpson, Nicholas J.;
Burtt, Noel P.;
Rayner, Nigel W.;
Saxena, Richa;
Ardlie, Kristin;
Tobias, Jonathan H.;
Ness, Andrew R.

Publication type:

Article

Common variants in WFS1 confer risk of type 2 diabetes.

Published in:

Nature Genetics, 2007, v. 39, n. 8, p. 951, doi. 10.1038/ng2067

By:

Sandhu, Manjinder S.;
Weedon, Michael N.;
Fawcett, Katherine A.;
Wasson, Jon;
Debenham, Sally L.;
Daly, Allan;
Lango, Hana;
Frayling, Timothy M.;
Neumann, Rosalind J.;
Sherva, Richard;
Blech, Ilana;
Pharoah, Paul D.;
Palmer, Colin N. A.;
Kimber, Charlotte;
Tavendale, Roger;
Morris, Andrew D.;
McCarthy, Mark I.;
Walker, Mark;
Hitman, Graham;
Glaser, Benjamin

Publication type:

Article

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts.

Published in:

2025

By:

Luckett, Amber M.;
Oram, Richard A.;
Deutsch, Aaron J.;
Ortega, Hector I.;
Fraser, Diane P.;
Ashok, Kaavya;
Manning, Alisa K.;
Mercader, Josep M.;
Rivas, Manuel A.;
Udler, Miriam S.;
Weedon, Michael N.;
Gloyn, Anna L.;
Sharp, Seth A.

Publication type:

Letter

Type 1 Diabetes Genetic Risk Score Differentiates Subgroups of Ketosis-Prone Diabetes.

Published in:

Diabetes Care, 2023, v. 46, n. 10, p. 1778, doi. 10.2337/dc23-0622

By:

Osafehinti, Deborah;
Mulukutla, Surya N.;
Hampe, Christiane S.;
Gaba, Ruchi;
Ram, Nalini;
Weedon, Michael N.;
Oram, Richard A.;
Balasubramanyam, Ashok

Publication type:

Article

Utility of Diabetes Type-Specific Genetic Risk Scores for the Classification of Diabetes Type Among Multiethnic Youth.

Published in:

2022

By:

Oram, Richard A.;
Sharp, Seth A.;
Pihoker, Catherine;
Ferrat, Lauric;
Imperatore, Giuseppina;
Williams, Adrienne;
Redondo, Maria J.;
Wagenknecht, Lynne;
Dolan, Lawrence M.;
Lawrence, Jean M.;
Weedon, Michael N.;
D'Agostino Jr., Ralph;
Hagopian, William A.;
Divers, Jasmin;
Dabelea, Dana;
D'Agostino, Ralph

Publication type:

journal article

Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study.

Published in:

2022

By:

Junxi Liu;
Richmond, Rebecca C.;
Bowden, Jack;
Barry, Ciarrah;
Dashti, Hassan S.;
Daghlas, Iyas;
Lane, Jacqueline M.;
Jones, Samuel E.;
Wood, Andrew R.;
Frayling, Timothy M.;
Wright, Alison K.;
Carr, Matthew J.;
Anderson, Simon G.;
Emsley, Richard A.;
Ray, David W.;
Weedon, Michael N.;
Saxena, Richa;
Lawlor, Deborah A.;
Rutter, Martin K.;
Liu, Junxi

Publication type:

journal article

Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis.

Published in:

2019

By:

Sharp, Seth A.;
Rich, Stephen S.;
Wood, Andrew R.;
Jones, Samuel E.;
Beaumont, Robin N.;
Harrison, James W.;
Schneider, Darius A.;
Locke, Jonathan M.;
Tyrrell, Jess;
Weedon, Michael N.;
Hagopian, William A.;
Oram, Richard A.

Publication type:

journal article

Zinc Transporter 8 Autoantibodies (ZnT8A) and a Type 1 Diabetes Genetic Risk Score Can Exclude Individuals With Type 1 Diabetes From Inappropriate Genetic Testing for Monogenic Diabetes.

Published in:

2019

By:

Patel, Kashyap A.;
Weedon, Michael N.;
Shields, Beverley M.;
Pearson, Ewan R.;
Hattersley, Andrew T.;
McDonald, Timothy J.;
UNITED study team

Publication type:

Letter

Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data.

Published in:

2018

By:

Dennis, John M.;
Henley, William E.;
Weedon, Michael N.;
Lonergan, Mike;
Rodgers, Lauren R.;
Jones, Angus G.;
Hamilton, William T.;
Sattar, Naveed;
Janmohamed, Salim;
Holman, Rury R.;
Pearson, Ewan R.;
Shields, Beverley M.;
Hattersley, Andrew T.;
MASTERMIND Consortium

Publication type:

journal article

A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk.

Published in:

2018

By:

Redondo, Maria J.;
Geyer, Susan;
Steck, Andrea K.;
Sharp, Seth;
Wentworth, John M.;
Weedon, Michael N.;
Antinozzi, Peter;
Sosenko, Jay;
Atkinson, Mark;
Pugliese, Alberto;
Oram, Richard A.;
Type 1 Diabetes TrialNet Study Group

Publication type:

journal article

Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy.

Published in:

2018

By:

Dennis, John M.;
Shields, Beverley M.;
Hill, Anita V.;
Knight, Bridget A.;
McDonald, Timothy J.;
Rodgers, Lauren R.;
Weedon, Michael N.;
Henley, William E.;
Sattar, Naveed;
Holman, Rury R.;
Pearson, Ewan R.;
Hattersley, Andrew T.;
Jones, Angus G.;
MASTERMIND Consortium

Publication type:

journal article

A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults.

Published in:

2016

By:

Oram, Richard A.;
Patel, Kashyap;
Hill, Anita;
Shields, Beverley;
McDonald, Timothy J.;
Jones, Angus;
Hattersley, Andrew T.;
Weedon, Michael N.

Publication type:

journal article

Adherence to Oral Glucose-Lowering Therapies and Associations With 1-Year HbA1c: A Retrospective Cohort Analysis in a Large Primary Care Database.

Published in:

2016

By:

Farmer, Andrew J.;
Rodgers, Lauren R.;
Lonergan, Mike;
Shields, Beverley;
Weedon, Michael N.;
Donnelly, Louise;
Holman, Rury R.;
Pearson, Ewan R.;
Hattersley, Andrew T.;
MASTERMIND Consortium

Publication type:

journal article

Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals.

Published in:

PLoS Genetics, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pgen.1002439

By:

Yingleong Chan;
Holmen, Oddgeir L.;
Dauber, Andrew;
Vatten, Lars;
Havulinna, Aki S.;
Skorpen, Frank;
Kvaløy, Kirsti;
Silander, Kaisa;
Nguyen, Thutrang T.;
Willer, Cristen;
Boehnke, Michael;
Perola, Markus;
Palotie, Aarno;
Salomaa, Veikko;
Hveem, Kristian;
Frayling, Timothy M.;
Hirschhorn, Joel N.;
Weedon, Michael N.

Publication type:

Article

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs).

Published in:

PLoS Genetics, 2008, v. 4, n. 5, p. 1, doi. 10.1371/journal.pgen.1000072

By:

Melzer, David;
Perry, John R. B.;
Hernandez, Dena;
Corsi, Anna-Maria;
Stevens, Kara;
Rafferty, Ian;
Lauretani, Fulvio;
Murray, Anna;
Gibbs, J. Raphael;
Paolisso, Giuseppe;
Rafiq, Sajjad;
Simon-Sanchez, Javier;
Lango, Hana;
Scholz, Sonja;
Weedon, Michael N.;
Arepalli, Sampath;
Rice, Neil;
Washecka, Nicole;
Hurst, Alison;
Britton, Angela

Publication type:

Article

Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction.

Published in:

PLoS Medicine, 2006, v. 3, n. 10, p. 1877, doi. 10.1371/journal.pmed.0030374

By:

Weedon, Michael N.;
McCarthy, Mark I.;
Hitman, Graham;
Walker, Mark;
Groves, Christopher J.;
Zeggini, Eleftheria;
Rayner, N. William;
Shields, Beverley;
Owen, Katharine R.;
Hattersley, Andrew T.;
Frayling, Timothy M.

Publication type:

Article

Comparison of Genetic Liability for Sleep Traits Among Individuals With Bipolar Disorder I or II and Control Participants.

Published in:

2020

By:

Lewis, Katie J. S.;
Richards, Alexander;
Karlsson, Robert;
Leonenko, Ganna;
Jones, Samuel E.;
Jones, Hannah J.;
Gordon-Smith, Katherine;
Forty, Liz;
Escott-Price, Valentina;
Owen, Michael J.;
Weedon, Michael N.;
Jones, Lisa;
Craddock, Nick;
Jones, Ian;
Landén, Mikael;
O'Donovan, Michael C.;
Di Florio, Arianna

Publication type:

journal article

A homozygous TARS2 variant is a novel cause of syndromic neonatal diabetes.

Published in:

Diabetic Medicine, 2025, v. 42, n. 3, p. 1, doi. 10.1111/dme.15471

By:

Donis, Russell;
Patel, Kashyap A.;
Wakeling, Matthew N.;
Johnson, Matthew B.;
Amoli, Masha M.;
Yildiz, Melek;
Akçay, Teoman;
Aspi, Irani;
Yong, James;
Yaghootkar, Hanieh;
Weedon, Michael N.;
Hattersley, Andrew T.;
Flanagan, Sarah E.;
De Franco, Elisa

Publication type:

Article

Letters to the Editors Cushing's disease as the first clinical manifestation of multiple endocrine neoplasia type 1 (MEN1) associated with an R460X mutation of the MEN1 gene.

Published in:

2004

By:

Matsuzaki, Lisa N.;
Canto-Costa, Marcelo H.S.;
Hauache, Omar M.;
Siddique, H.;
Smith, J.C.;
Corrall, R.J.M.;
Weedon, Michael N.;
Hattersley, Andrew T.;
Frayling, Timothy M.;
Van Beneden, Ronald;
Michel, Luc;
Havaux, Xavier;
Delos, Monique;
Donckier, Julian;
Park, John K.;
Ozata, Metin;
Chorich, Lynn P.;
Lili Cheng, Lynn P.;
Bick, David P.

Publication type:

Letter

Variants in the aromatase gene and on the Y-chromosome are not associated with adult height or insulin resistance in a UK population.

Published in:

Clinical Endocrinology, 2003, v. 59, n. 2, p. 175, doi. 10.1046/j.1365-2265.2003.01797.x

By:

Weedon, Michael N.;
Turner, Martina;
Knight, Beatrice;
Clark, Penny;
Hattersley, Andrew T.;
Frayling, Timothy M.

Publication type:

Article

Penetrance and expressivity of mitochondrial variants in a large clinically unselected population.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 5, p. 465, doi. 10.1093/hmg/ddad194

By:

Cannon, Stuart J;
Hall, Timothy;
Hawkes, Gareth;
Colclough, Kevin;
Boggan, Roisin M;
Wright, Caroline F;
Pickett, Sarah J;
Hattersley, Andrew T;
Weedon, Michael N;
Patel, Kashyap A

Publication type:

Article

Corrigendum to: A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin–creatinine ratio.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 9, p. 1544, doi. 10.1093/hmg/ddac022

By:

Casanova, Francesco;
Tyrrell, Jessica;
Beaumont, Robin N;
Ji, Yingjie;
Jones, Samuel E;
Hattersley, Andrew T;
Weedon, Michael N;
Murray, Anna;
Shore, Angela C;
Frayling, Timothy M;
Wood, Andrew R

Publication type:

Article

Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records.

Published in:

BMC Medical Genomics, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s12920-023-01658-w

By:

Ruth, Katherine S.;
Beaumont, Robin N.;
Locke, Jonathan M.;
Tyrrell, Jessica;
Crandall, Carolyn J.;
Hawkes, Gareth;
Frayling, Timothy M.;
Prague, Julia K.;
Patel, Kashyap A.;
Wood, Andrew R.;
Weedon, Michael N.;
Murray, Anna

Publication type:

Article

Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity.

Published in:

Nature Genetics, 2015, v. 47, n. 8, p. 921, doi. 10.1038/ng.3340

By:

Usher, Christina L;
Pato, Carlos N;
Pato, Michele T;
McCarthy, Mark I;
Altshuler, David M;
Handsaker, Robert E;
McCarroll, Steven A;
Esko, Tõnu;
Tuke, Marcus A;
Weedon, Michael N;
Frayling, Timothy M;
Hastie, Alex R;
Cao, Han;
Moon, Jennifer E;
Hirschhorn, Joel N;
Kashin, Seva;
Fuchsberger, Christian;
Boehnke, Michael;
Metspalu, Andres

Publication type:

Article

A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome.

Published in:

Nature Genetics, 2015, v. 47, n. 7, p. 814, doi. 10.1038/ng.3313

By:

Alakbarzade, Vafa;
Warner, Thomas T;
Hameed, Abdul;
Quek, Debra Q Y;
Nguyen, Long N;
Silver, David L;
Chioza, Barry A;
Sreekantan-Nair, Ajith;
Weedon, Michael N;
Crosby, Andrew H;
Baple, Emma L;
Cazenave-Gassiot, Amaury;
Wenk, Markus R;
Ahmad, Arshia Q;
Rich, Phil;
Patton, Michael A

Publication type:

Article

Defining the role of common variation in the genomic and biological architecture of adult human height.

Published in:

Nature Genetics, 2014, v. 46, n. 11, p. 1173, doi. 10.1038/ng.3097

By:

Wood, Andrew R;
Pasko, Dorota;
Weedon, Michael N;
Frayling, Timothy M;
Kutalik, Zoltán;
Hassinen, Maija;
Hayward, Caroline;
Wright, Alan F;
Heard-Costa, Nancy L;
Helmer, Quinta;
Hillege, Hans L;
Hlatky, Mark A;
Assimes, Themistocles L;
Quertermous, Thomas;
Hoffmann, Wolfgang;
Völzke, Henry;
Hoffmann, Per;
Holmen, Oddgeir;
Hveem, Kristian;
Houwing-Duistermaat, Jeanine J

Publication type:

Article

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

Published in:

Nature Genetics, 2014, v. 46, n. 10, p. 1131, doi. 10.1038/ng.3093

By:

Heap, Graham A;
Bampton, Peter;
Bell, Sally;
Cole, Andy;
Connor, Susan J;
Creed, Tom;
Cummings, Fraser R;
D'Amato, Mauro;
Fedorak, Richard N;
Florin, Timothy H;
Gaya, Daniel R;
Weedon, Michael N;
Greig, Emma;
Halfvarson, Jonas;
Hart, Alisa;
Irving, Peter M;
Jones, Gareth;
Lees, Charlie;
Satsangi, Jack;
Karban, Amir

Publication type:

Article

Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.

Published in:

Nature Genetics, 2014, v. 46, n. 1, p. 61, doi. 10.1038/ng.2826

By:

Weedon, Michael N;
Cebola, Inês;
Patch, Ann-Marie;
Flanagan, Sarah E;
De Franco, Elisa;
Caswell, Richard;
Rodríguez-Seguí, Santiago A;
Shaw-Smith, Charles;
Cho, Candy H-H;
Allen, Hana Lango;
Houghton, Jayne A L;
Roth, Christian L;
Chen, Rongrong;
Hussain, Khalid;
Marsh, Phil;
Vallier, Ludovic;
Murray, Anna;
Ellard, Sian;
Ferrer, Jorge;
Hattersley, Andrew T

Publication type:

Article

An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy.

Published in:

Nature Genetics, 2013, v. 45, n. 8, p. 947, doi. 10.1038/ng.2670

By:

Weedon, Michael N;
Ellard, Sian;
Prindle, Marc J;
Caswell, Richard;
Allen, Hana Lango;
Oram, Richard;
Godbole, Koumudi;
Yajnik, Chittaranjan S;
Sbraccia, Paolo;
Novelli, Giuseppe;
Turnpenny, Peter;
McCann, Emma;
Goh, Kim Jee;
Wang, Yukai;
Fulford, Jonathan;
McCulloch, Laura J;
Savage, David B;
O'Rahilly, Stephen;
Kos, Katarina;
Loeb, Lawrence A

Publication type:

Article

SavvyCNV: Genome-wide CNV calling from off-target reads.

Published in:

PLoS Computational Biology, 2022, v. 18, n. 3, p. 1, doi. 10.1371/journal.pcbi.1009940

By:

Laver, Thomas W.;
De Franco, Elisa;
Johnson, Matthew B.;
Patel, Kashyap A.;
Ellard, Sian;
Weedon, Michael N.;
Flanagan, Sarah E.;
Wakeling, Matthew N.

Publication type:

Article

Hyperglycaemia is a causal risk factor for upper limb pathologies.

Published in:

International Journal of Epidemiology, 2024, v. 53, n. 1, p. 1, doi. 10.1093/ije/dyad187

By:

Green, Harry D;
Burden, Ella;
Chen, Ji;
Evans, Jonathan;
Patel, Kashyap;
Wood, Andrew R;
Beaumont, Robin N;
Tyrrell, Jessica;
Frayling, Timothy M;
Hattersley, Andrew T;
Oram, Richard A;
Bowden, Jack;
Barroso, Inês;
Smith, Christopher;
Weedon, Michael N

Publication type:

Article

Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study.

Published in:

2020

By:

Green, Harry D;
Beaumont, Robin N;
Wood, Andrew R;
Hamilton, Benjamin;
Jones, Samuel E;
Goodhand, James R;
Kennedy, Nicholas A;
Ahmad, Tariq;
Yaghootkar, Hanieh;
Weedon, Michael N;
Frayling, Timothy M;
Tyrrell, Jessica

Publication type:

journal article

Using genetics to understand the causal influence of higher BMI on depression.

Published in:

2019

By:

Tyrrell, Jessica;
Mulugeta, Anwar;
Wood, Andrew R;
Zhou, Ang;
Beaumont, Robin N;
Tuke, Marcus A;
Jones, Samuel E;
Ruth, Katherine S;
Yaghootkar, Hanieh;
Sharp, Seth;
Thompson, William D;
Ji, Yingjie;
Harrison, Jamie;
Freathy, Rachel M;
Murray, Anna;
Weedon, Michael N;
Lewis, Cathryn;
Frayling, Timothy M;
Hyppönen, Elina

Publication type:

journal article

Gene-obesogenic environment interactions in the UK Biobank study.

Published in:

2017

By:

Tyrrell, Jessica;
Wood, Andrew R.;
Ames, Ryan M.;
Yaghootkar, Hanieh;
Beaumont, Robin N.;
Jones, Samuel E.;
Tuke, Marcus A.;
Ruth, Katherine S.;
Freathy, Rachel M.;
Smith, George Davey;
Joost, Stéphane;
Guessous, Idris;
Murray, Anna;
Strachan, David P.;
Kutalik, Zolt_n;
Weedon, Michael N.;
Frayling, Timothy M.;
Davey Smith, George;
Kutalik, Zoltán

Publication type:

journal article