Works by Weedon, Michael N

Results: 135
    1

    Genome-wide association analysis of composite sleep health scores in 413,904 individuals.

    Published in:
    Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07514-0
    By:
    • Goodman, Matthew O.;
    • Faquih, Tariq;
    • Paz, Valentina;
    • Nagarajan, Pavithra;
    • Lane, Jacqueline M.;
    • Spitzer, Brian;
    • Maher, Matthew;
    • Chung, Joon;
    • Cade, Brian E.;
    • Purcell, Shaun M.;
    • Zhu, Xiaofeng;
    • Noordam, Raymond;
    • Phillips, Andrew J. K.;
    • Kyle, Simon D.;
    • Spiegelhalder, Kai;
    • Weedon, Michael N.;
    • Lawlor, Deborah A.;
    • Rotter, Jerome I.;
    • Taylor, Kent D.;
    • Isasi, Carmen R.
    Publication type:
    Article
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    Estimating disease prevalence in large datasets using genetic risk scores.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26501-7
    By:
    • Evans, Benjamin D.;
    • Słowiński, Piotr;
    • Hattersley, Andrew T.;
    • Jones, Samuel E.;
    • Sharp, Seth;
    • Kimmitt, Robert A.;
    • Weedon, Michael N.;
    • Oram, Richard A.;
    • Tsaneva-Atanasova, Krasimira;
    • Thomas, Nicholas J.
    Publication type:
    Article
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    Genomic inflation factors under polygenic inheritance.

    Published in:
    European Journal of Human Genetics, 2011, v. 19, n. 7, p. 807, doi. 10.1038/ejhg.2011.39
    By:
    • Yang, Jian;
    • Weedon, Michael N.;
    • Purcell, Shaun;
    • Lettre, Guillaume;
    • Estrada, Karol;
    • Willer, Cristen J.;
    • Smith, Albert V.;
    • Ingelsson, Erik;
    • O'Connell, Jeffrey R.;
    • Mangino, Massimo;
    • Mägi, Reedik;
    • Madden, Pamela A.;
    • Heath, Andrew C.;
    • Nyholt, Dale R.;
    • Martin, Nicholas G.;
    • Montgomery, Grant W.;
    • Frayling, Timothy M.;
    • Hirschhorn, Joel N.;
    • McCarthy, Mark I.;
    • Goddard, Michael E.
    Publication type:
    Article
    9

    Predicting human height by Victorian and genomic methods.

    Published in:
    European Journal of Human Genetics, 2009, v. 17, n. 8, p. 1070, doi. 10.1038/ejhg.2009.5
    By:
    • Aulchenko, Yurii S.;
    • Struchalin, Maksim V.;
    • Belonogova, Nadezhda M.;
    • Axenovich, Tatiana I.;
    • Weedon, Michael N.;
    • Hofman, Albert;
    • Uitterlinden, Andre G.;
    • Kayser, Manfred;
    • Oostra, Ben A.;
    • van Duijn, Cornelia M.;
    • Janssens, A. Cecile J. W.;
    • Borodin, Pavel M.
    Publication type:
    Article
    10

    Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.

    Published in:
    European Journal of Human Genetics, 2007, v. 15, n. 6, p. 679, doi. 10.1038/sj.ejhg.5201802
    By:
    • Barber, Thomas M.;
    • Bennett, Amanda J.;
    • Gloyn, Anna L.;
    • Groves, Christopher J.;
    • Sovio, Ulla;
    • Ruokonen, Aimo;
    • Martikainen, Hannu;
    • Pouta, Anneli;
    • Taponen, Saara;
    • Weedon, Michael N.;
    • Hartikainen, Anna-Liisa;
    • Wass, John A. H.;
    • Järvelin, Marjo-Riitta;
    • Zeggini, Eleftheria;
    • Franks, Stephen;
    • McCarthy, Mark I.
    Publication type:
    Article
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    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

    Published in:
    2011
    By:
    • Heid, Iris M;
    • Jackson, Anne U;
    • Randall, Joshua C;
    • Winkler, Thomas W;
    • Qi, Lu;
    • Steinthorsdottir, Valgerdur;
    • Thorleifsson, Gudmar;
    • Zillikens, M Carola;
    • Speliotes, Elizabeth K;
    • Mägi, Reedik;
    • Workalemahu, Tsegaselassie;
    • White, Charles C;
    • Bouatia-Naji, Nabila;
    • Harris, Tamara B;
    • Berndt, Sonja I;
    • Ingelsson, Erik;
    • Willer, Cristen J;
    • Weedon, Michael N;
    • Luan, Jian'an;
    • Vedantam, Sailaja
    Publication type:
    Correction Notice
    13

    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

    Published in:
    Nature Genetics, 2010, v. 42, n. 11, p. 937, doi. 10.1038/ng.686
    By:
    • Speliotes, Elizabeth K.;
    • Willer, Cristen J.;
    • Berndt, Sonja I.;
    • Monda, Keri L.;
    • Thorleifsson, Gudmar;
    • Jackson, Anne U.;
    • Allen, Hana Lango;
    • Lindgren, Cecilia M.;
    • Luan, Jian'an;
    • Mägi, Reedik;
    • Randall, Joshua C.;
    • Vedantam, Sailaja;
    • Winkler, Thomas W.;
    • Lu Qi;
    • Workalemahu, Tsegaselassie;
    • Heid, Iris M.;
    • Steinthorsdottir, Valgerdur;
    • Stringham, Heather M.;
    • Weedon, Michael N.;
    • Wheeler, Eleanor
    Publication type:
    Article
    14

    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

    Published in:
    Nature Genetics, 2010, v. 42, n. 11, p. 949, doi. 10.1038/ng.685
    By:
    • Heid, Iris M.;
    • Jackson, Anne U.;
    • Randall, Joshua C.;
    • Winkler, Thomas W.;
    • Lu Qi;
    • Steinthorsdottir, Valgerdur;
    • Thorleifsson, Gudmar;
    • Zillikens, M. Carola;
    • Speliotes, Elizabeth K.;
    • Mägi, Reedik;
    • Workalemahu, Tsegaselassie;
    • White, Charles C.;
    • Bouatia-Naji, Nabila;
    • Harris, Tamara B.;
    • Berndt, Sonja I.;
    • Ingelsson, Erik;
    • Willer, Cristen J.;
    • Weedon, Michael N.;
    • Luan, Jian'an;
    • Vedantam, Sailaja
    Publication type:
    Article
    15

    Genome-wide association analysis identifies 20 loci that influence adult height.

    Published in:
    Nature Genetics, 2008, v. 40, n. 5, p. 575, doi. 10.1038/ng.121
    By:
    • Weedon, Michael N.;
    • Lango, Hana;
    • Lindgren, Cecilia M.;
    • Wallace, Chris;
    • Evans, David M.;
    • Mangino, Massimo;
    • Freathy, Rachel M.;
    • Perry, John R. B.;
    • Stevens, Suzanne;
    • Hall, Alistair S.;
    • Samani, Nilesh J.;
    • Shields, Beverly;
    • Prokopenko, Inga;
    • Farrall, Martin;
    • Dominiczak, Anna;
    • Johnson, Toby;
    • Bergmann, Sven;
    • Beckmann, Jacques S.;
    • Vollenweider, Peter;
    • Waterworth, Dawn M.
    Publication type:
    Article
    16

    A common variant of HMGA2 is associated with adult and childhood height in the general population.

    Published in:
    Nature Genetics, 2007, v. 39, n. 10, p. 1245, doi. 10.1038/ng2121
    By:
    • Weedon, Michael N.;
    • Lettre, Guillaume;
    • Freathy, Rachel M.;
    • Lindgren, Cecilia M.;
    • Voight, Benjamin F.;
    • Perry, John R. B.;
    • Elliott, Katherine S.;
    • Hackett, Rachel;
    • Guiducci, Candace;
    • Shields, Beverley;
    • Zeggini, Eleftheria;
    • Lango, Hana;
    • Lyssenko, Valeriya;
    • Timpson, Nicholas J.;
    • Burtt, Noel P.;
    • Rayner, Nigel W.;
    • Saxena, Richa;
    • Ardlie, Kristin;
    • Tobias, Jonathan H.;
    • Ness, Andrew R.
    Publication type:
    Article
    17

    Common variants in WFS1 confer risk of type 2 diabetes.

    Published in:
    Nature Genetics, 2007, v. 39, n. 8, p. 951, doi. 10.1038/ng2067
    By:
    • Sandhu, Manjinder S.;
    • Weedon, Michael N.;
    • Fawcett, Katherine A.;
    • Wasson, Jon;
    • Debenham, Sally L.;
    • Daly, Allan;
    • Lango, Hana;
    • Frayling, Timothy M.;
    • Neumann, Rosalind J.;
    • Sherva, Richard;
    • Blech, Ilana;
    • Pharoah, Paul D.;
    • Palmer, Colin N. A.;
    • Kimber, Charlotte;
    • Tavendale, Roger;
    • Morris, Andrew D.;
    • McCarthy, Mark I.;
    • Walker, Mark;
    • Hitman, Graham;
    • Glaser, Benjamin
    Publication type:
    Article
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    Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals.

    Published in:
    PLoS Genetics, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pgen.1002439
    By:
    • Yingleong Chan;
    • Holmen, Oddgeir L.;
    • Dauber, Andrew;
    • Vatten, Lars;
    • Havulinna, Aki S.;
    • Skorpen, Frank;
    • Kvaløy, Kirsti;
    • Silander, Kaisa;
    • Nguyen, Thutrang T.;
    • Willer, Cristen;
    • Boehnke, Michael;
    • Perola, Markus;
    • Palotie, Aarno;
    • Salomaa, Veikko;
    • Hveem, Kristian;
    • Frayling, Timothy M.;
    • Hirschhorn, Joel N.;
    • Weedon, Michael N.
    Publication type:
    Article
    30

    A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs).

    Published in:
    PLoS Genetics, 2008, v. 4, n. 5, p. 1, doi. 10.1371/journal.pgen.1000072
    By:
    • Melzer, David;
    • Perry, John R. B.;
    • Hernandez, Dena;
    • Corsi, Anna-Maria;
    • Stevens, Kara;
    • Rafferty, Ian;
    • Lauretani, Fulvio;
    • Murray, Anna;
    • Gibbs, J. Raphael;
    • Paolisso, Giuseppe;
    • Rafiq, Sajjad;
    • Simon-Sanchez, Javier;
    • Lango, Hana;
    • Scholz, Sonja;
    • Weedon, Michael N.;
    • Arepalli, Sampath;
    • Rice, Neil;
    • Washecka, Nicole;
    • Hurst, Alison;
    • Britton, Angela
    Publication type:
    Article
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    A homozygous TARS2 variant is a novel cause of syndromic neonatal diabetes.

    Published in:
    Diabetic Medicine, 2025, v. 42, n. 3, p. 1, doi. 10.1111/dme.15471
    By:
    • Donis, Russell;
    • Patel, Kashyap A.;
    • Wakeling, Matthew N.;
    • Johnson, Matthew B.;
    • Amoli, Masha M.;
    • Yildiz, Melek;
    • Akçay, Teoman;
    • Aspi, Irani;
    • Yong, James;
    • Yaghootkar, Hanieh;
    • Weedon, Michael N.;
    • Hattersley, Andrew T.;
    • Flanagan, Sarah E.;
    • De Franco, Elisa
    Publication type:
    Article
    34

    Letters to the Editors Cushing's disease as the first clinical manifestation of multiple endocrine neoplasia type 1 (MEN1) associated with an R460X mutation of the MEN1 gene.

    Published in:
    2004
    By:
    • Matsuzaki, Lisa N.;
    • Canto-Costa, Marcelo H.S.;
    • Hauache, Omar M.;
    • Siddique, H.;
    • Smith, J.C.;
    • Corrall, R.J.M.;
    • Weedon, Michael N.;
    • Hattersley, Andrew T.;
    • Frayling, Timothy M.;
    • Van Beneden, Ronald;
    • Michel, Luc;
    • Havaux, Xavier;
    • Delos, Monique;
    • Donckier, Julian;
    • Park, John K.;
    • Ozata, Metin;
    • Chorich, Lynn P.;
    • Lili Cheng, Lynn P.;
    • Bick, David P.
    Publication type:
    Letter
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    Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity.

    Published in:
    Nature Genetics, 2015, v. 47, n. 8, p. 921, doi. 10.1038/ng.3340
    By:
    • Usher, Christina L;
    • Pato, Carlos N;
    • Pato, Michele T;
    • McCarthy, Mark I;
    • Altshuler, David M;
    • Handsaker, Robert E;
    • McCarroll, Steven A;
    • Esko, Tõnu;
    • Tuke, Marcus A;
    • Weedon, Michael N;
    • Frayling, Timothy M;
    • Hastie, Alex R;
    • Cao, Han;
    • Moon, Jennifer E;
    • Hirschhorn, Joel N;
    • Kashin, Seva;
    • Fuchsberger, Christian;
    • Boehnke, Michael;
    • Metspalu, Andres
    Publication type:
    Article
    40

    A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome.

    Published in:
    Nature Genetics, 2015, v. 47, n. 7, p. 814, doi. 10.1038/ng.3313
    By:
    • Alakbarzade, Vafa;
    • Warner, Thomas T;
    • Hameed, Abdul;
    • Quek, Debra Q Y;
    • Nguyen, Long N;
    • Silver, David L;
    • Chioza, Barry A;
    • Sreekantan-Nair, Ajith;
    • Weedon, Michael N;
    • Crosby, Andrew H;
    • Baple, Emma L;
    • Cazenave-Gassiot, Amaury;
    • Wenk, Markus R;
    • Ahmad, Arshia Q;
    • Rich, Phil;
    • Patton, Michael A
    Publication type:
    Article
    41

    Defining the role of common variation in the genomic and biological architecture of adult human height.

    Published in:
    Nature Genetics, 2014, v. 46, n. 11, p. 1173, doi. 10.1038/ng.3097
    By:
    • Wood, Andrew R;
    • Pasko, Dorota;
    • Weedon, Michael N;
    • Frayling, Timothy M;
    • Kutalik, Zoltán;
    • Hassinen, Maija;
    • Hayward, Caroline;
    • Wright, Alan F;
    • Heard-Costa, Nancy L;
    • Helmer, Quinta;
    • Hillege, Hans L;
    • Hlatky, Mark A;
    • Assimes, Themistocles L;
    • Quertermous, Thomas;
    • Hoffmann, Wolfgang;
    • Völzke, Henry;
    • Hoffmann, Per;
    • Holmen, Oddgeir;
    • Hveem, Kristian;
    • Houwing-Duistermaat, Jeanine J
    Publication type:
    Article
    42

    HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

    Published in:
    Nature Genetics, 2014, v. 46, n. 10, p. 1131, doi. 10.1038/ng.3093
    By:
    • Heap, Graham A;
    • Bampton, Peter;
    • Bell, Sally;
    • Cole, Andy;
    • Connor, Susan J;
    • Creed, Tom;
    • Cummings, Fraser R;
    • D'Amato, Mauro;
    • Fedorak, Richard N;
    • Florin, Timothy H;
    • Gaya, Daniel R;
    • Weedon, Michael N;
    • Greig, Emma;
    • Halfvarson, Jonas;
    • Hart, Alisa;
    • Irving, Peter M;
    • Jones, Gareth;
    • Lees, Charlie;
    • Satsangi, Jack;
    • Karban, Amir
    Publication type:
    Article
    43

    Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.

    Published in:
    Nature Genetics, 2014, v. 46, n. 1, p. 61, doi. 10.1038/ng.2826
    By:
    • Weedon, Michael N;
    • Cebola, Inês;
    • Patch, Ann-Marie;
    • Flanagan, Sarah E;
    • De Franco, Elisa;
    • Caswell, Richard;
    • Rodríguez-Seguí, Santiago A;
    • Shaw-Smith, Charles;
    • Cho, Candy H-H;
    • Allen, Hana Lango;
    • Houghton, Jayne A L;
    • Roth, Christian L;
    • Chen, Rongrong;
    • Hussain, Khalid;
    • Marsh, Phil;
    • Vallier, Ludovic;
    • Murray, Anna;
    • Ellard, Sian;
    • Ferrer, Jorge;
    • Hattersley, Andrew T
    Publication type:
    Article
    44

    An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy.

    Published in:
    Nature Genetics, 2013, v. 45, n. 8, p. 947, doi. 10.1038/ng.2670
    By:
    • Weedon, Michael N;
    • Ellard, Sian;
    • Prindle, Marc J;
    • Caswell, Richard;
    • Allen, Hana Lango;
    • Oram, Richard;
    • Godbole, Koumudi;
    • Yajnik, Chittaranjan S;
    • Sbraccia, Paolo;
    • Novelli, Giuseppe;
    • Turnpenny, Peter;
    • McCann, Emma;
    • Goh, Kim Jee;
    • Wang, Yukai;
    • Fulford, Jonathan;
    • McCulloch, Laura J;
    • Savage, David B;
    • O'Rahilly, Stephen;
    • Kos, Katarina;
    • Loeb, Lawrence A
    Publication type:
    Article
    45

    SavvyCNV: Genome-wide CNV calling from off-target reads.

    Published in:
    PLoS Computational Biology, 2022, v. 18, n. 3, p. 1, doi. 10.1371/journal.pcbi.1009940
    By:
    • Laver, Thomas W.;
    • De Franco, Elisa;
    • Johnson, Matthew B.;
    • Patel, Kashyap A.;
    • Ellard, Sian;
    • Weedon, Michael N.;
    • Flanagan, Sarah E.;
    • Wakeling, Matthew N.
    Publication type:
    Article
    46

    Hyperglycaemia is a causal risk factor for upper limb pathologies.

    Published in:
    International Journal of Epidemiology, 2024, v. 53, n. 1, p. 1, doi. 10.1093/ije/dyad187
    By:
    • Green, Harry D;
    • Burden, Ella;
    • Chen, Ji;
    • Evans, Jonathan;
    • Patel, Kashyap;
    • Wood, Andrew R;
    • Beaumont, Robin N;
    • Tyrrell, Jessica;
    • Frayling, Timothy M;
    • Hattersley, Andrew T;
    • Oram, Richard A;
    • Bowden, Jack;
    • Barroso, Inês;
    • Smith, Christopher;
    • Weedon, Michael N
    Publication type:
    Article
    47
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    Using genetics to understand the causal influence of higher BMI on depression.

    Published in:
    2019
    By:
    • Tyrrell, Jessica;
    • Mulugeta, Anwar;
    • Wood, Andrew R;
    • Zhou, Ang;
    • Beaumont, Robin N;
    • Tuke, Marcus A;
    • Jones, Samuel E;
    • Ruth, Katherine S;
    • Yaghootkar, Hanieh;
    • Sharp, Seth;
    • Thompson, William D;
    • Ji, Yingjie;
    • Harrison, Jamie;
    • Freathy, Rachel M;
    • Murray, Anna;
    • Weedon, Michael N;
    • Lewis, Cathryn;
    • Frayling, Timothy M;
    • Hyppönen, Elina
    Publication type:
    journal article
    49

    Gene-obesogenic environment interactions in the UK Biobank study.

    Published in:
    2017
    By:
    • Tyrrell, Jessica;
    • Wood, Andrew R.;
    • Ames, Ryan M.;
    • Yaghootkar, Hanieh;
    • Beaumont, Robin N.;
    • Jones, Samuel E.;
    • Tuke, Marcus A.;
    • Ruth, Katherine S.;
    • Freathy, Rachel M.;
    • Smith, George Davey;
    • Joost, Stéphane;
    • Guessous, Idris;
    • Murray, Anna;
    • Strachan, David P.;
    • Kutalik, Zolt_n;
    • Weedon, Michael N.;
    • Frayling, Timothy M.;
    • Davey Smith, George;
    • Kutalik, Zoltán
    Publication type:
    journal article
    50

    Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

    Published in:
    PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0185083
    By:
    • Pilling, Luke C.;
    • Atkins, Janice L.;
    • Duff, Michael O.;
    • Beaumont, Robin N.;
    • Jones, Samuel E.;
    • Tyrrell, Jessica;
    • Kuo, Chia-Ling;
    • Ruth, Katherine S.;
    • Tuke, Marcus A.;
    • Yaghootkar, Hanieh;
    • Wood, Andrew R.;
    • Murray, Anna;
    • Weedon, Michael N.;
    • Harries, Lorna W.;
    • Kuchel, George A.;
    • Ferrucci, Luigi;
    • Frayling, Timothy M.;
    • Melzer, David
    Publication type:
    Article