Works by Weber, Martin S.

Results: 69

CONFIDENCE treatment success: long-term real-world effectiveness and safety of ocrelizumab in Germany.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1564327

By:

Buttmann, Mathias;
Weber, Martin S.;
Meuth, Sven G.;
Blümich, Sandra;
Hieke-Schulz, Stefanie;
Dirks, Petra;
Eggebrecht, Julius C.;
Ziemssen, Tjalf

Publication type:

Article

Intrathecal anti- CD20 efficiently depletes meningeal B cells in CNS autoimmunity.

Published in:

Annals of Clinical & Translational Neurology, 2014, v. 1, n. 7, p. 490, doi. 10.1002/acn3.71

By:

Lehmann‐Horn, Klaus;
Kinzel, Silke;
Feldmann, Linda;
Radelfahr, Florentine;
Hemmer, Bernhard;
Traffehn, Sarah;
Bernard, Claude C. A.;
Stadelmann, Christine;
Brück, Wolfgang;
Weber, Martin S.

Publication type:

Article

Targeting B Cells and Microglia in Multiple Sclerosis With Bruton Tyrosine Kinase Inhibitors: A Review.

Published in:

JAMA Neurology, 2023, v. 80, n. 4, p. 404, doi. 10.1001/jamaneurol.2022.5332

By:

Dybowski, Sarah;
Torke, Sebastian;
Weber, Martin S.

Publication type:

Article

Anti–Myelin Oligodendrocyte Glycoprotein Antibody–Associated Central Nervous System Demyelination—A Novel Disease Entity?

Published in:

2018

By:

Weber, Martin S.;
Derfuss, Tobias;
Brück, Wolfgang

Publication type:

Opinion

Targeting Central Nervous System B Cells in Progression of Multiple Sclerosis.

Published in:

JAMA Neurology, 2015, v. 72, n. 12, p. 1407, doi. 10.1001/jamaneurol.2015.2869

By:

Fereidan-Esfahani, Mahboobeh;
Brück, Wolfgang;
Weber, Martin S.

Publication type:

Article

Therapeutic Decisions in Multiple Sclerosis Moving Beyond Efficacy.

Published in:

JAMA Neurology, 2013, v. 70, n. 10, p. 1315, doi. 10.1001/jamaneurol.2013.3510

By:

Brück, Wolfgang;
Gold, Ralf;
Lund, Brett T.;
Oreja-Guevara, Celia;
Prat, Alexandre;
Spencer, Collin M.;
Steinman, Lawrence;
Tintoré, Mar;
Vollmer, Timothy L.;
Weber, Martin S.;
Weiner, Leslie P.;
Ziemssen, Tjalf;
Zamvil, Scott S.

Publication type:

Article

Editorial: Multiple Sclerosis – From Bench to Bedside: Currents Insights Into Pathophysiological Concepts and Their Potential Impact on Patients.

Published in:

2020

By:

Rommer, Paulus S.;
Weber, Martin S.;
Illes, Zsolt;
Zettl, Uwe K.

Publication type:

Editorial

Immunological Aspects of Approved MS Therapeutics.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01564

By:

Rommer, Paulus S.;
Milo, Ron;
Han, May H.;
Satyanarayan, Sammita;
Sellner, Johann;
Hauer, Larissa;
Illes, Zsolt;
Warnke, Clemens;
Laurent, Sarah;
Weber, Martin S.;
Zhang, Yinan;
Stuve, Olaf

Publication type:

Article

Disease-Modifying Agents for Multiple Sclerosis: Recent Advances and Future Prospects.

Published in:

Drugs, 2008, v. 68, n. 17, p. 2445, doi. 10.2165/0003495-200868170-00004

By:

Menge, Til;
Weber, Martin S.;
Hemmer, Bernhard;
Kieseier, Bernd C.;
von Büdingen, Hans-Christian;
Warnke, Clemens;
Zamvil, Scott S.;
Boster, Aaron;
Khan, Omar;
Hartung, Hans-Peter;
Stüve, Olaf

Publication type:

Article

Pharmacological Treatment of Early Multiple Sclerosis.

Published in:

Drugs, 2008, v. 68, n. 1, p. 73, doi. 10.2165/00003495-200868010-00005

By:

Stüve, Olaf;
Bennett, Jeffrey L.;
Hemmer, Bernhard;
Wiendl, Heinz;
Racke, Michael K.;
Bar-Or, Amit;
Wei Hu;
Zivadinov, Robert;
Weber, Martin S.;
Zamvil, Scott S.;
Pacheco, Maria F.;
Menge, Til;
Hartung, Hans-Peter;
Kieseier, Bernd C.;
Frohman, Elliot M.

Publication type:

Article

Bruton's tyrosine kinase as a promising therapeutic target for multiple sclerosis.

Published in:

Expert Opinion on Therapeutic Targets, 2023, v. 27, n. 4/5, p. 347, doi. 10.1080/14728222.2023.2218615

By:

Saberi, Darius;
Geladaris, Anastasia;
Dybowski, Sarah;
Weber, Martin S.

Publication type:

Article

Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis.

Published in:

Brain Pathology, 2019, v. 29, n. 5, p. 640, doi. 10.1111/bpa.12711

By:

Traub, Jan;
Traffehn, Sarah;
Ochs, Jasmin;
Häusser‐Kinzel, Silke;
Stephan, Schirin;
Scannevin, Robert;
Brück, Wolfgang;
Metz, Imke;
Weber, Martin S.

Publication type:

Article

Type II monocytes modulate T cell–mediated central nervous system autoimmune disease.

Published in:

Nature Medicine, 2007, v. 13, n. 8, p. 935, doi. 10.1038/nm1620

By:

Weber, Martin S.;
Prod'homme, Thomas;
Youssef, Sawsan;
Dunn, Shannon E.;
Rundle, Cynthia D.;
Lee, Linda;
Patarroyo, Juan C.;
Stüve, Olaf;
Sobel, Raymond A.;
Steinman, Lawrence;
Zamvil, Scott S.

Publication type:

Article

T effectors outfox T regulators in autoimmunity.

Published in:

Nature Medicine, 2007, v. 13, n. 4, p. 411, doi. 10.1038/nm0407-411

By:

Prod'homme, Thomas;
Weber, Martin S.;
Zamvil, Scott S.

Publication type:

Article

Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose: Aktueller Stand und Empfehlungen in Deutschland.

Published in:

Der Nervenarzt, 2019, v. 90, n. 12, p. 1245, doi. 10.1007/s00115-019-0760-0

By:

Bittner, Stefan;
Engel, Sinah;
Lange, Christoph;
Weber, Martin S.;
Haghikia, Aiden;
Luessi, Felix;
Korn, Thomas;
Klotz, Luisa;
Bayas, Antonios;
Paul, Friedemann;
Heesen, Christoph;
Stangel, Martin;
Wildemann, Brigitte;
Bergh, Florian Then;
Tackenberg, Björn;
Trebst, Corinna;
Warnke, Clemens;
Linker, Ralf;
Kerschensteiner, Martin;
Zettl, Uwe

Publication type:

Article

CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010066

By:

Lieschke, Simone;
Zechmeister, Bozena;
Haupt, Matteo;
Xuan Zheng;
Fengyan Jin;
Hein, Katharina;
Weber, Martin S.;
Hermann, Dirk M.;
Bähr, Mathias;
Kilic, Ertugrul;
Doeppner, Thorsten R.

Publication type:

Article

The Role of Peripheral CNS-Directed Antibodies in Promoting Inflammatory CNS Demyelination.

Published in:

Brain Sciences (2076-3425), 2017, v. 7, n. 7, p. 70, doi. 10.3390/brainsci7070070

By:

Kinzel, Silke;
Weber, Martin S.

Publication type:

Article

Efficacy and safety results after >3.5 years of treatment with the Bruton's tyrosine kinase inhibitor evobrutinib in relapsing multiple sclerosis: Long-term follow-up of a Phase II randomised clinical trial with a cerebrospinal fluid sub-study.

Published in:

Multiple Sclerosis Journal, 2024, v. 30, n. 4/5, p. 558, doi. 10.1177/13524585241234783

By:

Montalban, Xavier;
Piasecka-Stryczynska, Karolina;
Kuhle, Jens;
Benkert, Pascal;
Arnold, Douglas L;
Weber, Martin S;
Seitzinger, Andrea;
Guehring, Hans;
Shaw, Jamie;
Tomic, Davorka;
Hyvert, Yann;
Harlow, Danielle E;
Dyroff, Martin;
Wolinsky, Jerry S

Publication type:

Article

B Cell-Directed Therapeutics in Multiple Sclerosis: Rationale and Clinical Evidence.

Published in:

2016

By:

Kinzel, Silke;
Weber, Martin;
Weber, Martin S

Publication type:

journal article

Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action.

Published in:

2011

By:

Lalive PH;
Neuhaus O;
Benkhoucha M;
Burger D;
Hohlfeld R;
Zamvil SS;
Weber MS;
Lalive, Patrice H;
Neuhaus, Oliver;
Benkhoucha, Mahdia;
Burger, Danielle;
Hohlfeld, Reinhard;
Zamvil, Scott S;
Weber, Martin S

Publication type:

journal article

Repetitive Pertussis Toxin Promotes Development of Regulatory T Cells and Prevents Central Nervous System Autoimmune Disease.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0016009

By:

Weber, Martin S.;
Benkhoucha, Mahdia;
Lehmann-Horn, Klaus;
Hertzenberg, Deetje;
Sellner, Johann;
Santiago-Raber, Marie-Laure;
Chofflon, Michel;
Hemmer, Bernhard;
Zamvil, Scott S.;
Lalive, Patrice H.

Publication type:

Article

Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion.

Published in:

FASEB Journal, 2019, v. 33, n. 7, p. 8634, doi. 10.1096/fj.201900337R

By:

Garcia-Agudo, Laura Fernandez;
Janova, Hana;
Sendler, Lea E.;
Arinrad, Sahab;
Steixner, Agnes A.;
Hassouna, Imam;
Balmuth, Evan;
Ronnenberg, Anja;
Schopf, Nadine;
van der Flier, Felicia J.;
Begemann, Martin;
Martens, Henrik;
Weber, Martin S.;
Boretius, Susann;
Nave, Klaus-Armin;
Ehrenreich, Hannelore

Publication type:

Article

Favourable response to plasma exchange in tumefactive CNS demyelination with delayed B-cell response.

Published in:

2012

By:

Seifert, Christian L;
Wegner, Christiane;
Sprenger, Till;
Weber, Martin S;
Brück, Wolfgang;
Hemmer, Bernhard;
Sellner, Johann

Publication type:

Case Study

Developmental maturation of innate immune cell function correlates with susceptibility to central nervous system autoimmunity.

Published in:

European Journal of Immunology, 2013, v. 43, n. 8, p. 2078, doi. 10.1002/eji.201343338

By:

Hertzenberg, Deetje;
Lehmann‐Horn, Klaus;
Kinzel, Silke;
Husterer, Veronika;
Cravens, Petra D.;
Kieseier, Bernd C.;
Hemmer, Bernhard;
Brück, Wolfgang;
Zamvil, Scott S.;
Stüve, Olaf;
Weber, Martin S.

Publication type:

Article

Proinflammatory CD20+ T cells contribute to CNS-directed autoimmunity.

Published in:

Science Translational Medicine, 2022, v. 14, n. 638, p. 1, doi. 10.1126/scitranslmed.abi4632

By:

Ochs, Jasmin;
Nissimov, Nitzan;
Torke, Sebastian;
Freier, Marie;
Grondey, Katja;
Koch, Julian;
Klein, Matthias;
Feldmann, Linda;
Gudd, Cathrin;
Bopp, Tobias;
Häusser-Kinzel, Silke;
Weber, Martin S.

Publication type:

Article

Reply: Neither human nor mouse is hypercalcaemic with 250 nmol/l 25-hydroxyvitamin D.

Published in:

2020

By:

Häusler, Darius;
Torke, Sebastian;
Peelen, Evelyn;
Bertsch, Thomas;
Weber, Matthias;
Heilmann, Marcus;
Djukic, Marija;
Nau, Roland;
Larochelle, Catherine;
Zamvil, Scott S;
Brück, Wolfgang;
Weber, Martin S

Publication type:

Letter

Reply: Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis.

Published in:

2019

By:

Häusler, Darius;
Torke, Sebastian;
Peelen, Evelyn;
Bertsch, Thomas;
Djukic, Marija;
Nau, Roland;
Larochelle, Catherine;
Zamvil, Scott S;
Brück, Wolfgang;
Weber, Martin S

Publication type:

Letter

High dose vitamin D exacerbates central nervous system autoimmunity by raising T-cell excitatory calcium.

Published in:

2019

By:

Häusler, Darius;
Torke, Sebastian;
Peelen, Evelyn;
Bertsch, Thomas;
Djukic, Marija;
Nau, Roland;
Larochelle, Catherine;
Zamvil, Scott S;
Brück, Wolfgang;
Weber, Martin S

Publication type:

journal article

Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo.

Published in:

Brain: A Journal of Neurology, 2004, v. 127, n. 6, p. 1370, doi. 10.1093/brain/awh163

By:

Martin S. Weber;
Michaela Starck;
Stefan Wagenpfeil;
Edgar Meinl;
Reinhard Hohlfeld;
Cinthia Farina

Publication type:

Article

Proinflammatory CD20+ T Cells are Differentially Affected by Multiple Sclerosis Therapeutics.

Published in:

2021

By:

Quendt, Corinna;
Ochs, Jasmin;
Häusser‐Kinzel, Silke;
Häusler, Darius;
Weber, Martin S.;
Häusser-Kinzel, Silke

Publication type:

journal article

Efficacy and Safety of the Bruton's Tyrosine Kinase Inhibitor (BTKI) Evobrutinib in Relapsing Multiple Sclerosis over 108 Weeks: Open-Label Extension to a Phase 2 Study.

Published in:

International Journal of MS Care, 2020, v. 22, n. S2, p. 87

By:

Montalban, Xavier;
Arnold, Douglas L.;
Weber, Martin S.;
Staikov, Ivan;
Piasecka-Stryczynska, Karolina;
Martin, Emily C.;
Mandel, Matthew;
Ona, Victor;
Dangond, Fernando;
Wolinsky, Jerry S.

Publication type:

Article

(DXT36) Effect of Evobrutinib, a Bruton's Tyrosine Kinase Inhibitor, on Immune Cell and Immunoglobulin Levels over 48 Weeks in a Phase 2 Study in Relapsing Multiple Sclerosis.

Published in:

International Journal of MS Care, 2020, v. 22, n. S2, p. 28

By:

Montalban, Xavier;
Shaw, Jamie;
Syed, Sana;
Dangond, Fernando;
Martin, Emily C.;
Grenningloh, Roland;
Weber, Martin S.

Publication type:

Article

Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity.

Published in:

2006

By:

Stüve, Olaf;
Youssef, Sawsan;
Weber, Martin S.;
Nessler, Stefan;
von Budingen, Hans-Christian;
Hemmer, Bernhard;
Prod'homme, Thomas;
Sobel, Raymond A.;
Steinman, Lawrence;
Zamvil, Scott S.;
Stüve, Olaf;
von Büdingen, Hans-Christian

Publication type:

journal article

B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation.

Published in:

Scientific Reports, 2016, p. 34594, doi. 10.1038/srep34594

By:

Bjarnadóttir, Kristbjörg;
Benkhoucha, Mahdia;
Merkler, Doron;
Weber, Martin S.;
Payne, Natalie L.;
Bernard, Claude C. A.;
Molnarfi, Nicolas;
Lalive, Patrice H.

Publication type:

Article

Long-term analysis of infections and associated risk factors in patients with multiple sclerosis treated with ocrelizumab: pooled analysis of 13 interventional clinical trials.

Published in:

Therapeutic Advances in Neurological Disorders, 2024, p. 1, doi. 10.1177/17562864241277736

By:

Derfuss, Tobias;
Bermel, Robert;
Lin, Chien-Ju;
Hauser, Stephen L.;
Kappos, Ludwig;
Vollmer, Timothy;
Comi, Giancarlo;
Giovannoni, Gavin;
Hartung, Hans-Peter;
Weber, Martin S.;
Wang, Jianmei;
Jessop, Nikki;
Chognot, Cathy;
Craveiro, Licinio;
Bar-Or, Amit

Publication type:

Article

Long-term analysis of infections and associated risk factors in patients with multiple sclerosis treated with ocrelizumab: pooled analysis of 13 interventional clinical trials.

Published in:

Therapeutic Advances in Neurological Disorders, 2024, v. 17, p. 1, doi. 10.1177/17562864241277736

By:

Derfuss, Tobias;
Bermel, Robert;
Lin, Chien-Ju;
Hauser, Stephen L.;
Kappos, Ludwig;
Vollmer, Timothy;
Comi, Giancarlo;
Giovannoni, Gavin;
Hartung, Hans-Peter;
Weber, Martin S.;
Wang, Jianmei;
Jessop, Nikki;
Chognot, Cathy;
Craveiro, Licinio;
Bar-Or, Amit

Publication type:

Article

The Value of the Serum Neurofilament Protein Heavy Chain as a Biomarker for Peri-operative Brain Injury After Carotid Endarterectomy.

Published in:

Neurochemical Research, 2009, v. 34, n. 11, p. 1969, doi. 10.1007/s11064-009-9976-x

By:

Sellner, Johann;
Petzold, Axel;
Sadikovic, Suwad;
Esposito, Lorena;
Weber, Martin S.;
Heider, Peter;
Eckstein, Hans-Henning;
Hemmer, Bernhard;
Poppert, Holger

Publication type:

Article

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity.

Published in:

Annals of Neurology, 2010, v. 68, n. 3, p. 369, doi. 10.1002/ana.22081

By:

Weber, Martin S.;
Prod'homme, Thomas;
Patarroyo, Juan C.;
Molnarfi, Nicolas;
Karnezis, Tara;
Lehmann-Horn, Klaus;
Danilenko, Dimitry M.;
Eastham-Anderson, Jeffrey;
Slavin, Anthony J.;
Linington, Christopher;
Bernard, Claude C. A.;
Martin, Flavius;
Zamvil, Scott S.

Publication type:

Article

Primary Progressive Multiple Sclerosis: Putting Together the Puzzle.

Published in:

Frontiers in Neurology, 2017, p. 1, doi. 10.3389/fneur.2017.00234

By:

Abdelhak, Ahmed;
Weber, Martin S.;
Tumani, Hayrettin

Publication type:

Article

Targeting B cells in the treatment of multiple sclerosis: recent advances and remaining challenges.

Published in:

Therapeutic Advances in Neurological Disorders, 2013, v. 6, n. 3, p. 161, doi. 10.1177/1756285612474333

By:

Lehmann-Horn, Klaus;
Kronsbein, Helena C.;
Weber, Martin S.

Publication type:

Article

Modification of CSF findings in multiple sclerosis in the era of rapidly expanding treatment options.

Published in:

Expert Review of Neurotherapeutics, 2019, v. 19, n. 3, p. 277, doi. 10.1080/14737175.2019.1583557

By:

Giotaki, Ioanna;
Lange, Peter;
Weber, Martin S.

Publication type:

Article

Safety, Adherence and Persistence in a Real-World Cohort of German MS Patients Newly Treated With Ocrelizumab: First Insights From the CONFIDENCE Study.

Published in:

Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.863105

By:

Weber, Martin S.;
Buttmann, Mathias;
Meuth, Sven G.;
Dirks, Petra;
Muros-Le Rouzic, Erwan;
Eggebrecht, Julius C.;
Hieke-Schulz, Stefanie;
Leemhuis, Jost;
Ziemssen, Tjalf

Publication type:

Article

Differential Role of Factor XIII in Acute Myocardial Infarction and Ischemic Stroke.

Published in:

Biomedicines, 2024, v. 12, n. 3, p. 497, doi. 10.3390/biomedicines12030497

By:

Traub, Jan;
Weber, Martin S.;
Frey, Anna

Publication type:

Article

Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model.

Published in:

Nature Communications, 2016, v. 7, n. 11, p. 13275, doi. 10.1038/ncomms13275

By:

Romanelli, Elisa;
Merkler, Doron;
Mezydlo, Aleksandra;
Weil, Marie-Theres;
Weber, Martin S.;
Nikić, Ivana;
Potz, Stephanie;
Meinl, Edgar;
Matznick, Florian E. H.;
Kreutzfeldt, Mario;
Ghanem, Alexander;
Conzelmann, Karl-Klaus;
Metz, Imke;
Brück, Wolfgang;
Routh, Matthew;
Simons, Mikael;
Bishop, Derron;
Misgeld, Thomas;
Kerschensteiner, Martin

Publication type:

Article

Towards Treating Multiple Sclerosis Progression.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 11, p. 1474, doi. 10.3390/ph17111474

By:

Häusler, Darius;
Weber, Martin S.

Publication type:

Article

B Cells and Antibodies as Targets of Therapeutic Intervention in Neuromyelitis Optica Spectrum Disorders.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 1, p. 37, doi. 10.3390/ph14010037

By:

Traub, Jan;
Husseini, Leila;
Weber, Martin S.

Publication type:

Article

Neither T-helper type 2 nor Foxp3+ regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity.

Published in:

Journal of Neuroinflammation, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1742-2094-11-29

By:

Weber, Martin S.;
Prod'homme, Thomas;
Sawsan Youssef;
Dunn, Shannon E.;
Steinman, Lawrence;
Zamvil, Scott S.

Publication type:

Article

Neither T-helper type 2 nor Foxp3+ regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity.

Published in:

2014

By:

Weber, Martin S;
Prod'homme, Thomas;
Youssef, Sawsan;
Dunn, Shannon E;
Steinman, Lawrence;
Zamvil, Scott S

Publication type:

journal article

The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis.

Published in:

Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-67

By:

Cravens, Petra D.;
Kieseier, Bernd C.;
Hussain, Rehana;
Herndon, Emily;
Arellano, Benjamine;
Li-Hong Ben;
Timmons, Brenda C.;
Castro-Rojas, Cyd;
Hartung, Hans-Peter;
Hemmer, Bernhard;
Weber, Martin S.;
Zamvil, Scott S.;
Stüve, Olaf

Publication type:

Article

The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis.

Published in:

2013

By:

Cravens, Petra D;
Kieseier, Bernd C;
Hussain, Rehana;
Herndon, Emily;
Arellano, Benjamine;
Ben, Li-Hong;
Timmons, Brenda C;
Castro-Rojas, Cyd;
Hartung, Hans-Peter;
Hemmer, Bernhard;
Weber, Martin S;
Zamvil, Scott S;
Stüve, Olaf

Publication type:

journal article