Works by Watada, Hirotaka

Results: 301
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    Higher C-Peptide Level During Glucose Clamp Is Associated With Muscle Insulin Resistance in Nonobese Japanese Men.

    Published in:
    Journal of the Endocrine Society, 2019, v. 3, n. 10, p. 1847, doi. 10.1210/js.2019-00167
    By:
    • Kaga, Hideyoshi;
    • Tamura, Yoshifumi;
    • Takeno, Kageumi;
    • Kakehi, Saori;
    • Someya, Yuki;
    • Funayama, Takashi;
    • Furukawa, Yasuhiko;
    • Suzuki, Ruriko;
    • Sugimoto, Daisuke;
    • Kadowaki, Satoshi;
    • Nishitani-Yokoyama, Miho;
    • Shimada, Kazunori;
    • Daida, Hiroyuki;
    • Aoki, Shigeki;
    • Giacca, Adria;
    • Kanazawa, Akio;
    • Kawamori, Ryuzo;
    • Watada, Hirotaka
    Publication type:
    Article
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    Fatty Liver Has Stronger Association With Insulin Resistance Than Visceral Fat Accumulation in Nonobese Japanese Men.

    Published in:
    Journal of the Endocrine Society, 2019, v. 3, n. 7, p. 1409, doi. 10.1210/js.2019-00052
    By:
    • Kadowaki, Satoshi;
    • Tamura, Yoshifumi;
    • Someya, Yuki;
    • Takeno, Kageumi;
    • Kaga, Hideyoshi;
    • Sugimoto, Daisuke;
    • Kakehi, Saori;
    • Funayama, Takashi;
    • Furukawa, Yasuhiko;
    • Suzuki, Ruriko;
    • Nishitani-Yokoyama, Miho;
    • Shimada, Kazunori;
    • Daida, Hiroyuki;
    • Aoki, Shigeki;
    • Kanazawa, Akio;
    • Kawamori, Ryuzo;
    • Watada, Hirotaka
    Publication type:
    Article
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    Postprandial Plasma Glucagon Kinetics in Type 2 Diabetes Mellitus: Comparison of Immunoassay and Mass Spectrometry.

    Published in:
    Journal of the Endocrine Society, 2019, v. 3, n. 1, p. 42, doi. 10.1210/js.2018-00142
    By:
    • Katahira, Takehiro;
    • Kanazawa, Akio;
    • Shinohara, Mai;
    • Koshibu, Mami;
    • Kaga, Hideyoshi;
    • Mita, Tomoya;
    • Tosaka, Yuka;
    • Komiya, Koji;
    • Miyatsuka, Takeshi;
    • Ikeda, Fuki;
    • Azuma, Kosuke;
    • Takayanagi, Naoko;
    • Ogihara, Takeshi;
    • Ohmura, Chie;
    • Miyachi, Atsushi;
    • Mieno, Eri;
    • Yamashita, Satoko;
    • Watada, Hirotaka
    Publication type:
    Article
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    Glymphatic system impairment in nonathlete older male adults who played contact sports in their youth associated with cognitive decline: A diffusion tensor image analysis along the perivascular space study.

    Published in:
    Frontiers in Neurology, 2023, v. 14, p. 1, doi. 10.3389/fneur.2023.1100736
    By:
    • Yuichi Morita;
    • Koji Kamagata;
    • Andica, Christina;
    • Kaito Takabayashi;
    • Shohei Fujita;
    • Samoyeau, Thomas;
    • Uchida, Wataru;
    • Yuya Saito;
    • Hiroki Tabata;
    • Hitoshi Naito;
    • Yuki Someya;
    • Hideyoshi Kaga;
    • Yoshifumi Tamura;
    • Miyata, Mari;
    • Toshiaki Akashi;
    • Akihiko Wada;
    • Toshiaki Taoka;
    • Shinji Naganawa;
    • Hirotaka Watada;
    • Ryuzo Kawamori
    Publication type:
    Article
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    Rationale, design, and baseline characteristics of a clinical trial for prevention of atherosclerosis in patients with insulin-treated type 2 diabetes mellitus using DPP-4 inhibitor: the Sitagliptin Preventive study of Intima-media thickness Evaluation (SPIKE)

    Published in:
    Diabetology & Metabolic Syndrome, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-5996-6-35
    By:
    • Mita, Tomoya;
    • Katakami, Naoto;
    • Shiraiwa, Toshihiko;
    • Yoshii, Hidenori;
    • Onuma, Tomio;
    • Kuribayashi, Nobuichi;
    • Osonoi, Takeshi;
    • Kaneto, Hideaki;
    • Kosugi, Keisuke;
    • Umayahara, Yutaka;
    • Yamamoto, Tsunehiko;
    • Matsumoto, Kazunari;
    • Yokoyama, Hiroki;
    • Tsugawa, Mamiko;
    • Gosho, Masahiko;
    • Shimomura, Iichiro;
    • Watada, Hirotaka
    Publication type:
    Article
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    A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes.

    Published in:
    PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208654
    By:
    • Taira, Makiko;
    • Imamura, Minako;
    • Takahashi, Atsushi;
    • Kamatani, Yoichiro;
    • Yamauchi, Toshimasa;
    • Araki, Shin-ichi;
    • Tanaka, Nobue;
    • van Zuydam, Natalie R.;
    • Ahlqvist, Emma;
    • Toyoda, Masao;
    • Umezono, Tomoya;
    • Kawai, Koichi;
    • Imanishi, Masahito;
    • Watada, Hirotaka;
    • Suzuki, Daisuke;
    • Maegawa, Hiroshi;
    • Babazono, Tetsuya;
    • Kaku, Kohei;
    • Kawamori, Ryuzo;
    • null, null
    Publication type:
    Article
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    Serotonin regulates pancreatic beta cell mass during pregnancy.

    Published in:
    Nature Medicine, 2010, v. 16, n. 7, p. 804, doi. 10.1038/nm.2173
    By:
    • Hail Kim;
    • Toyofuku, Yukiko;
    • Lynn, Francis C;
    • Chak, Eric;
    • Uchida, Toyoyoshi;
    • Mizukami, Hiroki;
    • Fujitani, Yoshio;
    • Kawamori, Ryuzo;
    • Miyatsuka, Takeshi;
    • Kosaka, Yasuhiro;
    • Yang, Katherine;
    • Honig, Gerard;
    • van der Hart, Marieke;
    • Kishimoto, Nina;
    • Wang, Juehu;
    • Yagihashi, Soroku;
    • Tecott, Laurence H;
    • Watada, Hirotaka;
    • German, Michael S.
    Publication type:
    Article
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    A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.

    Published in:
    Nature Genetics, 2010, v. 42, n. 10, p. 864, doi. 10.1038/ng.660
    By:
    • Yamauchi, Toshimasa;
    • Hara, Kazuo;
    • Maeda, Shiro;
    • Yasuda, Kazuki;
    • Takahashi, Atsushi;
    • Horikoshi, Momoko;
    • Nakamura, Masahiro;
    • Fujita, Hayato;
    • Grarup, Niels;
    • Cauchi, Stephane;
    • Ng, Daniel P. K.;
    • Ma, Ronald C. W.;
    • Tsunoda, Tatsuhiko;
    • Kubo, Michiaki;
    • Watada, Hirotaka;
    • Maegawa, Hiroshi;
    • Okada-Iwabu, Miki;
    • Iwabu, Masato;
    • Shojima, Nobuhiro;
    • Hyoung Doo Shin
    Publication type:
    Article
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    Effects of Diet and Exercise on Muscle and Liver Intracellular Lipid Contents and Insulin Sensitivity in Type 2 Diabetic Patients.

    Published in:
    Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 6, p. 3191, doi. 10.1210/jc.2004-1959
    By:
    • Yoshifumi Tamura;
    • Yasushi Tanaka;
    • Fumihiko Sato;
    • Jong Bock Choi;
    • Hirotaka Watada;
    • Masataka Niwa;
    • Junichiro Kinoshita;
    • Aiko Ooka;
    • Naoki Kumashiro;
    • Yasuhiro Igarashi;
    • Shinsuke Kyogoku;
    • Tadayuki Maehara;
    • Masahiko Kawasumi;
    • Takahisa Hirose;
    • Ryuzo Kawamori
    Publication type:
    Article
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    Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial.

    Published in:
    Cardiovascular Diabetology, 2016, v. 15, p. 1, doi. 10.1186/s12933-016-0381-x
    By:
    • Tanaka, Atsushi;
    • Inoue, Teruo;
    • Kitakaze, Masafumi;
    • Oyama, Jun-ichi;
    • Sata, Masataka;
    • Taguchi, Isao;
    • Shimizu, Wataru;
    • Watada, Hirotaka;
    • Tomiyama, Hirofumi;
    • Ako, Junya;
    • Sakata, Yasushi;
    • Anzai, Toshihisa;
    • Uematsu, Masaaki;
    • Suzuki, Makoto;
    • Eguchi, Kazuo;
    • Yamashina, Akira;
    • Saito, Yoshihiko;
    • Sato, Yasunori;
    • Ueda, Shinichiro;
    • Murohara, Toyoaki
    Publication type:
    Article
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    Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined Phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative study.

    Published in:
    Cardiovascular Diabetology, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2840-13-65
    By:
    • Kohei Kaku;
    • Hirotaka Watada;
    • Yasuhiko Iwamoto;
    • Kazunori Utsunomiya;
    • Yasuo Terauchi;
    • Kazuyuki Tobe;
    • Yukio Tanizawa;
    • Eiichi Araki;
    • Masamichi Ueda;
    • Hideki Suganami;
    • Daisuke Watanabe
    Publication type:
    Article
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    HbA1c trajectories over 3 years in people with type 2 diabetes starting second‐line glucose‐lowering therapy: The prospective global DISCOVER study.

    Published in:
    Diabetes, Obesity & Metabolism, 2023, v. 25, n. 7, p. 1890, doi. 10.1111/dom.15050
    By:
    • Bongaerts, Brenda;
    • Kuss, Oliver;
    • Bonnet, Fabrice;
    • Chen, Hungta;
    • Cooper, Andrew;
    • Fenici, Peter;
    • Gomes, Marilia B.;
    • Hammar, Niklas;
    • Ji, Linong;
    • Khunti, Kamlesh;
    • Medina, Jesús;
    • Nicolucci, Antonio;
    • Shestakova, Marina V.;
    • Watada, Hirotaka;
    • Rathmann, Wolfgang
    Publication type:
    Article
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    Treatment patterns and glycated haemoglobin levels over 36 months in individuals with type 2 diabetes initiating second‐line glucose‐lowering therapy: The global DISCOVER study.

    Published in:
    Diabetes, Obesity & Metabolism, 2023, v. 25, n. 1, p. 46, doi. 10.1111/dom.14842
    By:
    • Charbonnel, Bernard H.;
    • Chen, Hungta;
    • Cid‐Ruzafa, Javier;
    • Cooper, Andrew;
    • Fenici, Peter;
    • Gomes, Marilia B.;
    • Saraiva, Gabriela L.;
    • Medina, Jesús;
    • Nicolucci, Antonio;
    • Shestakova, Marina V.;
    • Shimomura, Iichiro;
    • Surmont, Filip;
    • Tang, Fengming;
    • Vora, Jiten;
    • Watada, Hirotaka;
    • Khunti, Kamlesh
    Publication type:
    Article
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    Cover Image, Volume 24, Issue 12.

    Published in:
    Diabetes, Obesity & Metabolism, 2022, v. 24, n. 12, p. 1, doi. 10.1111/dom.14114
    By:
    • Kadowaki, Takashi;
    • Maegawa, Hiroshi;
    • Watada, Hirotaka;
    • Yabe, Daisuke;
    • Node, Koichi;
    • Murohara, Toyoaki;
    • Wada, Jun
    Publication type:
    Article
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    Factors associated with weight loss in people with overweight or obesity living with type 2 diabetes mellitus: Insights from the global DISCOVER study.

    Published in:
    Diabetes, Obesity & Metabolism, 2022, v. 24, n. 9, p. 1734, doi. 10.1111/dom.14745
    By:
    • Hejjaji, Vittal;
    • Gorgojo‐Martinez, Juan J.;
    • Tang, Fengming;
    • Garnelo, Julia Blanco;
    • Cooper, Andrew;
    • Medina, Jesús;
    • Mutiozabal, Miren Sequera;
    • Khunti, Kamlesh;
    • Nicolucci, Antonio;
    • Shestakova, Marina V.;
    • Ji, Linong;
    • Gomes, Marilia B.;
    • Watada, Hirotaka;
    • Vora, Jiten;
    • Malik, Ali O.;
    • Kosiborod, Mikhail;
    • Arnold, Suzanne V.
    Publication type:
    Article
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    Relationship between blood glucose variability in ambulatory glucose profile and standardized continuous glucose monitoring metrics: Subanalysis of a prospective cohort study.

    Published in:
    Diabetes, Obesity & Metabolism, 2022, v. 24, n. 1, p. 82, doi. 10.1111/dom.14550
    By:
    • Tokutsu, Akemi;
    • Okada, Yosuke;
    • Mita, Tomoya;
    • Torimoto, Keiichi;
    • Wakasugi, Satomi;
    • Katakami, Naoto;
    • Yoshii, Hidenori;
    • Uryu, Kohei;
    • Nishida, Keiko;
    • Arao, Tadashi;
    • Tanaka, Yoshiya;
    • Gosho, Masahiko;
    • Shimomura, Iichiro;
    • Watada, Hirotaka
    Publication type:
    Article
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    What are the factors associated with long‐term glycaemic control in patients with type 2 diabetes and elevated glycated haemoglobin (≥7.0%) at initiation of second‐line therapy? Results from the DISCOVER study.

    Published in:
    Diabetes, Obesity & Metabolism, 2021, v. 23, n. 10, p. 2336, doi. 10.1111/dom.14476
    By:
    • Bonnet, Fabrice;
    • Chen, Hungta;
    • Cooper, Andrew;
    • Gomes, Marίlia B.;
    • Ji, Linong;
    • Leigh, Paul;
    • Ramirez, Larisa;
    • Shestakova, Marina V.;
    • Shimomura, Iichiro;
    • Siddiqui, Afrah;
    • Tang, Fengming;
    • Vora, Jiten;
    • Watada, Hirotaka;
    • Khunti, Kamlesh
    Publication type:
    Article
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    Prevalence and progression of chronic kidney disease among patients with type 2 diabetes: Insights from the DISCOVER study.

    Published in:
    Diabetes, Obesity & Metabolism, 2021, v. 23, n. 8, p. 1956, doi. 10.1111/dom.14401
    By:
    • Khunti, Kamlesh;
    • Charbonnel, Bernard;
    • Chen, Hungta;
    • Cherney, David Z.;
    • Cooper, Andrew;
    • Fenici, Peter;
    • Gomes, Marilia B.;
    • Hammar, Niklas;
    • Heerspink, Hiddo J. L.;
    • Ji, Linong;
    • Medina, Jesús;
    • Nicolucci, Antonio;
    • Ramirez, Larisa;
    • Rathmann, Wolfgang;
    • Shestakova, Marina V.;
    • Shimomura, Iichiro;
    • Tang, Fengming;
    • Watada, Hirotaka;
    • Kosiborod, Mikhail
    Publication type:
    Article
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    Associations between second‐line glucose‐lowering combination therapies with metformin and HbA1c, body weight, quality of life, hypoglycaemic events and glucose‐lowering treatment intensification: The DISCOVER study.

    Published in:
    Diabetes, Obesity & Metabolism, 2021, v. 23, n. 8, p. 1823, doi. 10.1111/dom.14400
    By:
    • Khunti, Kamlesh;
    • Charbonnel, Bernard;
    • Cooper, Andrew;
    • Gomes, Marília B.;
    • Ji, Linong;
    • Leigh, Paul;
    • Nicolucci, Antonio;
    • Rathmann, Wolfgang;
    • Shestakova, Marina V.;
    • Siddiqui, Afrah;
    • Tang, Fengming;
    • Watada, Hirotaka;
    • Chen, Hungta
    Publication type:
    Article
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    Cover Image, Volume 23, Issue 5.

    Published in:
    Diabetes, Obesity & Metabolism, 2021, v. 23, n. 5, p. i, doi. 10.1111/dom.14406
    By:
    • Yamasaki, Nozomu;
    • Tamura, Yoshifumi;
    • Kaga, Hideyoshi;
    • Sato, Motonori;
    • Kiya, Mai;
    • Kadowaki, Satoshi;
    • Suzuki, Ruriko;
    • Furukawa, Yasuhiko;
    • Sugimoto, Daisuke;
    • Funayama, Takashi;
    • Someya, Yuki;
    • Kakehi, Saori;
    • Nojiri, Shuko;
    • Satoh, Hiroaki;
    • Kawamori, Ryuzo;
    • Watada, Hirotaka
    Publication type:
    Article
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    A decrease in plasma glucose levels is required for increased endogenous glucose production with a single administration of a sodium‐glucose co‐transporter‐2 inhibitor tofogliflozin.

    Published in:
    Diabetes, Obesity & Metabolism, 2021, v. 23, n. 5, p. 1092, doi. 10.1111/dom.14312
    By:
    • Yamasaki, Nozomu;
    • Tamura, Yoshifumi;
    • Kaga, Hideyoshi;
    • Sato, Motonori;
    • Kiya, Mai;
    • Kadowaki, Satoshi;
    • Suzuki, Ruriko;
    • Furukawa, Yasuhiko;
    • Sugimoto, Daisuke;
    • Funayama, Takashi;
    • Someya, Yuki;
    • Kakehi, Saori;
    • Nojiri, Shuko;
    • Satoh, Hiroaki;
    • Kawamori, Ryuzo;
    • Watada, Hirotaka
    Publication type:
    Article
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    Global patterns of comprehensive cardiovascular risk factor control in patients with type 2 diabetes mellitus: Insights from the DISCOVER study.

    Published in:
    Diabetes, Obesity & Metabolism, 2021, v. 23, n. 1, p. 39, doi. 10.1111/dom.14180
    By:
    • Patel, Krishna K.;
    • Gomes, Marilia B.;
    • Charbonnel, Bernard;
    • Chen, Hungta;
    • Cid‐Ruzafa, Javier;
    • Fenici, Peter;
    • Hammar, Niklas;
    • Ji, Linong;
    • Kennedy, Kevin F.;
    • Khunti, Kamlesh;
    • Kosiborod, Mikhail;
    • Pocock, Stuart;
    • Shestakova, Marina V.;
    • Shimomura, Iichiro;
    • Surmont, Filip;
    • Watada, Hirotaka;
    • Arnold, Suzanne V.
    Publication type:
    Article
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    Efficacy and safety of dapagliflozin in Japanese patients with inadequately controlled type 1 diabetes (DEPICT‐5): 52‐week results from a randomized, open‐label, phase III clinical trial.

    Published in:
    Diabetes, Obesity & Metabolism, 2020, v. 22, n. 4, p. 540, doi. 10.1111/dom.13922
    By:
    • Araki, Eiichi;
    • Watada, Hirotaka;
    • Uchigata, Yasuko;
    • Tomonaga, Osamu;
    • Fujii, Hitomi;
    • Ohashi, Hiroshi;
    • Okabe, Tadashi;
    • Asano, Michiko;
    • Thoren, Fredrik;
    • Kim, Hyosung;
    • Yajima, Toshitaka;
    • Langkilde, Anna Maria
    Publication type:
    Article
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