Works by Warmuth, Markus

Results: 12

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia.

Published in:

Nature Genetics, 2004, v. 36, n. 5, p. 453, doi. 10.1038/ng1343

By:

Hu, Yiguo;
Liu, Yuhua;
Pelletier, Shawn;
Buchdunger, Elisabeth;
Warmuth, Markus;
Fabbro, Doriano;
Hallek, Michael;
Van Etten, Richard A;
Li, Shaoguang

Publication type:

Article

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA).

Published in:

Cancer Chemotherapy & Pharmacology, 2019, v. 83, n. 1, p. 151, doi. 10.1007/s00280-018-3716-3

By:

Rioux, Nathalie;
Smith, Sherri;
Korpal, Manav;
O'Shea, Morgan;
Prajapati, Sudeep;
Zheng, Guo Zhu;
Warmuth, Markus;
Smith, Peter G.

Publication type:

Article

Effect of a high-fat meal on the relative bioavailability of H3B-6527, a novel FGFR4 inhibitor, in healthy volunteers.

Published in:

2019

By:

Rioux, Nathalie;
Kim, Amy;
Nix, Darrell;
Bowser, Todd;
Warmuth, Markus;
Smith, Peter G.;
Schindler, Joanne

Publication type:

journal article

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA).

Published in:

2018

By:

Rioux, Nathalie;
Smith, Sherri;
Korpal, Manav;
O'Shea, Morgan;
Prajapati, Sudeep;
Zheng, Guo Zhu;
Warmuth, Markus;
Smith, Peter G

Publication type:

journal article

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0176181

By:

Albacker, Lee A.;
Wu, Jeremy;
Smith, Peter;
Warmuth, Markus;
Stephens, Philip J.;
Zhu, Ping;
Yu, Lihua;
Chmielecki, Juliann

Publication type:

Article

Interaction of the receptor tyrosine kinase p145c- kit with the p210 bcr/abl kinase in myeloid cells.

Published in:

British Journal of Haematology, 1996, v. 94, n. 1, p. 5, doi. 10.1046/j.1365-2141.1996.6102053.x

By:

Hallek, Michael;
Danhauser-Riedl, Susanne;
Herbst, Ronald;
Warmuth, Markus;
Winkler, Almut;
Kolb, Hans-Jochen;
Druker, Brian;
Griffin, James D.;
Emmerich, Bertold;
Ullrich, Axel

Publication type:

Article

Allosteric inhibition of BCR-ABL.

Published in:

Cell Cycle, 2010, v. 9, n. 18, p. 3710, doi. 10.4161/cc.9.18.13232

By:

Hassan, A. Quamrul;
Sharma, Sreenath V.;
Warmuth, Markus

Publication type:

Article

Hedgehog pathway activation in chronic myeloid leukemia.

Published in:

Cell Cycle, 2010, v. 9, n. 17, p. 3449, doi. 10.4161/cc.9.17.12945

By:

Jagani, Zainab;
Dorsch, Marion;
Warmuth, Markus

Publication type:

Article

Essential role of stromally induced hedgehog signaling in B-cell malignancies.

Published in:

Nature Medicine, 2007, v. 13, n. 8, p. 944, doi. 10.1038/nm1614

By:

Dierks, Christine;
Grbic, Jovana;
Zirlik, Katja;
Beigi, Ronak;
Englund, Nathan P.;
Gui-Rong Guo;
Veelken, Hendrik;
Engelhardt, Monika;
Mertelsmann, Roland;
Kelleher, Joseph F.;
Schultz, Peter;
Warmuth, Markus

Publication type:

Article

Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08150-5

By:

Aird, Daniel;
Teng, Teng;
Huang, Chia-Ling;
Pazolli, Ermira;
Banka, Deepti;
Cheung-Ong, Kahlin;
Eifert, Cheryl;
Furman, Craig;
Wu, Zhenhua Jeremy;
Seiler, Michael;
Buonamici, Silvia;
Fekkes, Peter;
Karr, Craig;
Palacino, James;
Park, Eunice;
Smith, Peter G.;
Yu, Lihua;
Mizui, Yoshiharu;
Warmuth, Markus;
Chicas, Agustin

Publication type:

Article

Role of p21WAF1/CIP1 as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells.

Published in:

Annals of Hematology, 2008, v. 87, n. 3, p. 183, doi. 10.1007/s00277-007-0400-9

By:

Forster, Karin;
Obermeier, Axel;
Mitina, Olga;
Simon, Nicola;
Warmuth, Markus;
Krause, Günter;
Hallek, Michael

Publication type:

Article

Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner.

Published in:

Annals of Hematology, 2007, v. 86, n. 11, p. 777, doi. 10.1007/s00277-007-0344-0

By:

Mitina, Olga;
Warmuth, Markus;
Krause, Günter;
Hallek, Michael;
Obermeier, Axel

Publication type:

Article

Works by Warmuth, Markus

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia.

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA).

Effect of a high-fat meal on the relative bioavailability of H3B-6527, a novel FGFR4 inhibitor, in healthy volunteers.

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA).

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion.

Interaction of the receptor tyrosine kinase p145<sup>c- kit</sup> with the p210<sup> bcr/abl</sup> kinase in myeloid cells.

Allosteric inhibition of BCR-ABL.

Hedgehog pathway activation in chronic myeloid leukemia.

Essential role of stromally induced hedgehog signaling in B-cell malignancies.

Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators.

Role of p21<sup>WAF1/CIP1</sup> as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells.

Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner.