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Polyglutamine disease proteins: Commonalities and differences in interaction profiles and pathological effects.
- Published in:
- Proteomics, 2024, v. 24, n. 12/13, p. 1, doi. 10.1002/pmic.202300114
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- Publication type:
- Article
Interleukin‐12/23 deficiency differentially affects pathology in male and female Alzheimer's disease‐like mice.
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- EMBO Reports, 2020, v. 21, n. 3, p. 1, doi. 10.15252/embr.201948530
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- Article
Corrigendum: A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy.
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- 2019
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- Publication type:
- Correction Notice
The Induction Levels of Heat Shock Protein 70 Differentiate the Vulnerabilities to Mutant Huntingtin among Neuronal Subtypes.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 4, p. 868, doi. 10.1523/JNEUROSCI.4522-06.2007
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- Publication type:
- Article
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
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- Journal of Cell Biology, 2006, v. 172, n. 4, p. 589, doi. 10.1083/jcb.200509132
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- Publication type:
- Article
RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease.
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- Frontiers in Neurology, 2020, v. 11, p. N.PAG, doi. 10.3389/fneur.2020.573560
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- Publication type:
- Article
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
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- EMBO Journal, 2006, v. 25, n. 7, p. 1547, doi. 10.1038/sj.emboj.7601043
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- Article
Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington’s disease.
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- European Journal of Neuroscience, 2008, v. 28, n. 1, p. 30, doi. 10.1111/j.1460-9568.2008.06323.x
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- Publication type:
- Article
The polyphenol EGCG directly targets intracellular amyloid‐β aggregates and promotes their lysosomal degradation.
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- Journal of Neurochemistry, 2023, v. 166, n. 2, p. 294, doi. 10.1111/jnc.15842
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- Article
The pathobiology of perturbed mutant huntingtin protein–protein interactions in Huntington's disease.
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- Journal of Neurochemistry, 2019, v. 151, n. 4, p. 507, doi. 10.1111/jnc.14853
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- Publication type:
- Article
Detection of Alpha-Rod Protein Repeats Using a Neural Network and Application to Huntingtin.
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- PLoS Computational Biology, 2009, v. 5, n. 3, p. 1, doi. 10.1371/journal.pcbi.1000304
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- Publication type:
- Article
Mutant huntingtin impairs Ku70-mediated DNA repair.
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- Journal of Cell Biology, 2010, v. 189, n. 3, p. 425, doi. 10.1083/jcb.200905138
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- Publication type:
- Article
A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.
- Published in:
- Nature Communications, 2013, v. 4, n. 5, p. 1816, doi. 10.1038/ncomms2828
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- Publication type:
- Article
A Directed Protein Interaction Network for Investigating Intracellular Signal Transduction.
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- Science Signaling, 2011, v. 4, n. 189, p. 1, doi. 10.1126/scisignal.2001699
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- Publication type:
- Article
Small-molecule conversion of toxic oligomers to nontoxic ?-sheet-rich amyloid fibrils.
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- Nature Chemical Biology, 2012, v. 8, n. 1, p. 93, doi. 10.1038/nchembio.719
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- Publication type:
- Article
Dynamic Circadian Protein--Protein Interaction Networks Predict Temporal Organization of Cellular Functions.
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- PLoS Genetics, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.pgen.1003398
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- Publication type:
- Article
Identification of Human Proteins That Modify Misfolding and Proteotoxicity of Pathogenic Ataxin-1.
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- PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002897
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- Publication type:
- Article
The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios.
- Published in:
- FEBS Letters, 2015, v. 589, n. 1, p. 77, doi. 10.1016/j.febslet.2014.11.026
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- Publication type:
- Article
Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.
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- Human Molecular Genetics, 2016, v. 25, n. 8, p. 1600, doi. 10.1093/hmg/ddw036
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- Publication type:
- Article
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
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- Human Molecular Genetics, 2014, v. 23, n. 15, p. 4142, doi. 10.1093/hmg/ddu137
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- Publication type:
- Article
Myc inhibition impairs autophagosome formation.
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- Human Molecular Genetics, 2013, v. 22, n. 25, p. 5237, doi. 10.1093/hmg/ddt381
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- Publication type:
- Article
Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.
- Published in:
- Human Molecular Genetics, 2006, v. 15, n. 18, p. 2743, doi. 10.1093/hmg/ddl210
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- Publication type:
- Article
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
- Published in:
- Nature Communications, 2016, v. 7, n. 10, p. 13047, doi. 10.1038/ncomms13047
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- Publication type:
- Article
HIPPIE: Integrating Protein Interaction Networks with Experiment Based Quality Scores.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031826
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- Publication type:
- Article
A Novel Multiplex Cell Viability Assay for High-Throughput RNAi Screening.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028338
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- Publication type:
- Article
Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027408
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- Publication type:
- Article
Pathogenic Polyglutamine Tracts Are Potent Inducers of Spontaneous Sup35 and Rnq1 Amyloidogenesis.
- Published in:
- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009642
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- Publication type:
- Article
Glial Cell Lineage Expression of Mutant Ataxin-1 and Huntingtin Induces Developmental and Late-Onset Neuronal Pathologies in Drosophila Models.
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- PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004262
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- Publication type:
- Article
A Y2H-seq approach defines the human protein methyltransferase interactome.
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- Nature Methods, 2013, v. 10, n. 4, p. 339, doi. 10.1038/nmeth.2397
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- Article
Current Approaches Toward Quantitative Mapping of the Interactome.
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- Frontiers in Genetics, 2016, p. 1, doi. 10.3389/fgene.2016.00074
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- Publication type:
- Article
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.
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- Human Molecular Genetics, 2005, v. 14, n. 19, p. 2893, doi. 10.1093/hmg/ddi321
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- Publication type:
- Article
A molecular pathogenesis for transcription factor associated poly-alanine tract expansions.
- Published in:
- Human Molecular Genetics, 2004, v. 13, n. 20, p. 2351, doi. 10.1093/hmg/ddh277
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- Publication type:
- Article
The huntingtin interacting protein HIP1 is a clathrin and α -adaptin-binding protein involved in receptor-mediated endocytosis.
- Published in:
- Human Molecular Genetics, 2001, v. 10, n. 17, p. 1807, doi. 10.1093/hmg/10.17.1807
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- Publication type:
- Article
The huntingtin interacting protein HIP1 is a clathrin and α-adaptin-binding protein involved in receptor-mediated endocytosis.
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- Human Molecular Genetics, 2001, v. 10, n. 16
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- Publication type:
- Article
Formation of polyglutamine inclusions in non-CNS tissue.
- Published in:
- Human Molecular Genetics, 1999, v. 8, n. 5, p. 813, doi. 10.1093/hmg/8.5.813
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- Publication type:
- Article
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix.
- Published in:
- Human Molecular Genetics, 1998, v. 7, n. 6, p. 991, doi. 10.1093/hmg/7.6.991
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- Publication type:
- Article
HIP-I: A huntingtin interacting protein isolated by the yeast two-hybrid system.
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- Human Molecular Genetics, 1997, v. 6, n. 3, p. 487, doi. 10.1093/hmg/6.3.487
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- Publication type:
- Article
A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy.
- Published in:
- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2017.00439
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- Publication type:
- Article
HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration.
- Published in:
- PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001717
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- Publication type:
- Article
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
- Published in:
- Nature Cell Biology, 2007, v. 9, n. 4, p. 402, doi. 10.1038/ncb1553
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- Publication type:
- Article
HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1-3 and PKM2.
- Published in:
- Stem Cells, 2014, v. 32, n. 2, p. 364, doi. 10.1002/stem.1552
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- Publication type:
- Article
Aggregation-induced changes in the chemical exchange saturation transfer (CEST) signals of proteins.
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- NMR in Biomedicine, 2017, v. 30, n. 1, p. n/a, doi. 10.1002/nbm.3665
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- Publication type:
- Article
Repeated two-hybrid screening detects transient protein–protein interactions.
- Published in:
- Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2010, v. 125, n. 3-6, p. 613, doi. 10.1007/s00214-009-0651-8
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- Publication type:
- Article
Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.
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- Brain Communications, 2023, v. 5, n. 1, p. 1, doi. 10.1093/braincomms/fcad010
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- Publication type:
- Article
Development and application of a DNA microarray-based yeast two-hybrid system.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 3, p. 1496, doi. 10.1093/nar/gks1329
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- Publication type:
- Article
Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 10, p. 4273, doi. 10.1093/nar/gks011
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- Publication type:
- Article
UniHI 4: new tools for query, analysis and visualization of the human protein–protein interactome.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. suppl_1, p. D657, doi. 10.1093/nar/gkn841
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- Publication type:
- Article
UniHI: an entry gate to the human protein interactome.
- Published in:
- Nucleic Acids Research, 2007, v. 35, p. d590, doi. 10.1093/nar/gkl817
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- Publication type:
- Article
Counting CAG repeats in the Huntington’s disease gene by restriction endonuclease EcoP15I cleavage.
- Published in:
- Nucleic Acids Research, 2002, v. 30, n. 16, p. e83, doi. 10.1093/nar/gnf082
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- Publication type:
- Article
Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
- Published in:
- BioEssays, 2013, v. 35, n. 6, p. 503, doi. 10.1002/bies.201300001
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- Publication type:
- Article