Works by Waldmann, Herbert

Results: 420

An Indole Dearomatization Strategy for the Synthesis of Pseudo‐Natural Products.

Published in:

ChemBioChem, 2025, v. 26, n. 10, p. 1, doi. 10.1002/cbic.202500182

By:

Hoock, Joseph G. F.;
Burhop, Annina;
Greiner, Luca C.;
Schölermann, Beate;
Da Cruz Lopes Guita, Celine;
Liu, Jie;
Bag, Sukdev;
Pahl, Axel;
Sievers, Sonja;
Scheel, Rebecca;
Strohmann, Carsten;
Ziegler, Slava;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Collective Synthesis of Sarpagine and Macroline Alkaloid‐Inspired Compounds.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 5, p. 1, doi. 10.1002/chem.202303027

By:

Aoyama, Hikaru;
Davies, Caitlin;
Liu, Jie;
Pahl, Axel;
Kirchhoff, Jan‐Lukas;
Scheel, Rebecca;
Sievers, Sonja;
Strohmann, Carsten;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 67, p. 1, doi. 10.1002/chem.202202164

By:

Grigalunas, Michael;
Patil, Sohan;
Krzyzanowski, Adrian;
Pahl, Axel;
Flegel, Jana;
Schölermann, Beate;
Xie, Jianing;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Catalytic Atroposelective C7 Functionalisation of Indolines and Indoles.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 1, p. 1, doi. 10.1002/chem.202103365

By:

Shaaban, Saad;
Merten, Christian;
Waldmann, Herbert

Publication type:

Article

Corrigendum: Rh<sup>III</sup>‐Catalyzed C−H Activation of Aryl Hydroxamates for the Synthesis of Isoindolinones.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 65, p. 15046, doi. 10.1002/chem.202004559

By:

Shaaban, Saad;
Davies, Caitlin;
Merten, Christian;
Flegel, Jana;
Otte, Felix;
Strohmann, Carsten;
Waldmann, Herbert

Publication type:

Article

Rh<sup>III</sup>‐Catalyzed C−H Activation of Aryl Hydroxamates for the Synthesis of Isoindolinones.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 47, p. 10729, doi. 10.1002/chem.202002384

By:

Shaaban, Saad;
Davies, Caitlin;
Merten, Christian;
Flegel, Jana;
Otte, Felix;
Strohmann, Carsten;
Waldmann, Herbert

Publication type:

Article

Enantiodivergent Combination of Natural Product Scaffolds Enabled by Catalytic Enantioselective Cycloaddition.

Published in:

Angewandte Chemie, 2016, v. 128, n. 27, p. 7892, doi. 10.1002/ange.201602084

By:

Xu, Hao;
Golz, Christopher;
Strohmann, Carsten;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Organokatalytische Synthese von enantiomerenreinen 2 H- und 3 H-Pyrrolen: Inhibitoren des Hedgehog-Signalwegs.

Published in:

Angewandte Chemie, 2016, v. 128, n. 27, p. 7824, doi. 10.1002/ange.201602932

By:

Kötzner, Lisa;
Leutzsch, Markus;
Sievers, Sonja;
Patil, Sumersing;
Waldmann, Herbert;
Zheng, Yiying;
Thiel, Walter;
List, Benjamin

Publication type:

Article

Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity.

Published in:

Angewandte Chemie, 2016, v. 128, n. 27, p. 7897, doi. 10.1002/ange.201602666

By:

Qian, Yong;
Schürmann, Marc;
Janning, Petra;
Hedberg, Christian;
Waldmann, Herbert

Publication type:

Article

Reversible Inhibitoren arretieren ClpP in einer definierten Konformation, die durch Bindung von ClpX aufgehoben wird.

Published in:

Angewandte Chemie, 2015, v. 127, n. 52, p. 16121, doi. 10.1002/ange.201507266

By:

Pahl, Axel;
Lakemeyer, Markus;
Vielberg, Marie ‐ Theres;
Hackl, Mathias W.;
Vomacka, Jan;
Korotkov, Vadim S.;
Stein, Martin L.;
Fetzer, Christian;
Lorenz ‐ Baath, Katrin;
Richter, Klaus;
Waldmann, Herbert;
Groll, Michael;
Sieber, Stephan A.

Publication type:

Article

Direkte Modulation von Aktivität und Funktion kleiner GTPasen.

Published in:

Angewandte Chemie, 2015, v. 127, n. 46, p. 13718, doi. 10.1002/ange.201504357

By:

Cromm, Philipp M.;
Spiegel, Jochen;
Grossmann, Tom N.;
Waldmann, Herbert

Publication type:

Article

Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4.

Published in:

Angewandte Chemie, 2015, v. 127, n. 42, p. 12575, doi. 10.1002/ange.201501515

By:

Schröder, Peter;
Förster, Tim;
Kleine, Stefan;
Becker, Christian;
Richters, André;
Ziegler, Slava;
Rauh, Daniel;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Rhodium(II)-Catalyzed Enantioselective Synthesis of Troponoids.

Published in:

Angewandte Chemie, 2015, v. 127, n. 26, p. 7763, doi. 10.1002/ange.201502233

By:

Murarka, Sandip;
Jia, Zhi-Jun;
Merten, Christian;
Daniliuc, Constantin-G.;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling.

Published in:

Angewandte Chemie, 2015, v. 127, n. 19, p. 5688, doi. 10.1002/ange.201500112

By:

Švenda, Jakub;
Sheremet, Michael;
Kremer, Lea;
Maier, Lukáš;
Bauer, Jonathan O.;
Strohmann, Carsten;
Ziegler, Slava;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

(−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels.

Published in:

Angewandte Chemie, 2015, v. 127, n. 12, p. 3858, doi. 10.1002/ange.201411511

By:

Akbulut, Yasemin;
Gaunt, Hannah J.;
Muraki, Katsuhiko;
Ludlow, Melanie J.;
Amer, Mohamed S.;
Bruns, Alexander;
Vasudev, Naveen S.;
Radtke, Lea;
Willot, Matthieu;
Hahn, Sven;
Seitz, Tobias;
Ziegler, Slava;
Christmann, Mathias;
Beech, David J.;
Waldmann, Herbert

Publication type:

Article

Highly Enantioselective Intramolecular 1,3-Dipolar Cycloaddition: A Route to Piperidino-Pyrrolizidines.

Published in:

Angewandte Chemie, 2015, v. 127, n. 2, p. 661, doi. 10.1002/ange.201409942

By:

Vidadala, Srinivasa Rao;
Golz, Christopher;
Strohmann, Carsten;
Daniliuc, Constantin ‐ G.;
Waldmann, Herbert

Publication type:

Article

Die asymmetrische Hetero-Diels-Alder-Reaktion in Synthesen biologisch relevanter Verbindungen.

Published in:

Angewandte Chemie, 2014, v. 126, n. 42, p. 11326, doi. 10.1002/ange.201404094

By:

Eschenbrenner ‐ Lux, Vincent;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

The Antidote. Inside the World of New Pharma. Von Barry Werth.

Published in:

Angewandte Chemie, 2014, v. 126, n. 32, p. 8418, doi. 10.1002/ange.201405216

By:

Waldmann, Herbert

Publication type:

Article

A Cyclization-Rearrangement Cascade for the Synthesis of Structurally Complex Chiral Gold(I)-Aminocarbene Complexes.

Published in:

Angewandte Chemie, 2014, v. 126, n. 31, p. 8260, doi. 10.1002/ange.201403651

By:

Kolundžić, Filip;
Murali, Annamalai;
Pérez ‐ Galán, Patricia;
Bauer, Jonathan O.;
Strohmann, Carsten;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Direkte Modulation von Rab-GTPase-Effektor-Wechselwirkungen.

Published in:

Angewandte Chemie, 2014, v. 126, n. 9, p. 2531, doi. 10.1002/ange.201308568

By:

Spiegel, Jochen;
Cromm, Philipp M.;
Itzen, Aymelt;
Goody, Roger S.;
Grossmann, Tom N.;
Waldmann, Herbert

Publication type:

Article

An Enantioselective Inverse‐Electron‐Demand Imino Diels–Alder Reaction.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2166, doi. 10.1002/ange.201309022

By:

Eschenbrenner‐Lux, Vincent;
Küchler, Philipp;
Ziegler, Slava;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

An Enantioselective Inverse-Electron-Demand Imino Diels-Alder Reaction.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2166, doi. 10.1002/ange.201309022

By:

Eschenbrenner ‐ Lux, Vincent;
Küchler, Philipp;
Ziegler, Slava;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Catalytic Enantioselective Synthesis of Functionalized Tropanes Reveals Novel Inhibitors of Hedgehog Signaling.

Published in:

Angewandte Chemie, 2013, v. 125, n. 49, p. 13130, doi. 10.1002/ange.201307392

By:

Narayan, Rishikesh;
Bauer, Jonathan O.;
Strohmann, Carsten;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid-Inspired Compound Collection.

Published in:

Angewandte Chemie, 2013, v. 125, n. 47, p. 12630, doi. 10.1002/ange.201306948

By:

Takayama, Hiroshi;
Jia, Zhi ‐ Jun;
Kremer, Lea;
Bauer, Jonathan O.;
Strohmann, Carsten;
Ziegler, Slava;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Discovery of Neuritogenic Compound Classes Inspired by Natural Products.

Published in:

Angewandte Chemie, 2013, v. 125, n. 36, p. 9755, doi. 10.1002/ange.201302045

By:

Dakas, Pierre ‐ Yves;
Parga, Juan A.;
Höing, Susanne;
Schöler, Hans R.;
Sterneckert, Jared;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Berichtigung: Highly Enantioselective Catalytic [6+3] Cycloadditions of Azomethine Ylides.

Published in:

Angewandte Chemie, 2013, v. 125, n. 29, p. 7484, doi. 10.1002/ange.201304263

By:

Potowski, Marco;
Bauer, Jonathan O.;
Strohmann, Carsten;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Der Inhibitionsmechanismus der caseinolytischen Protease (ClpP).

Published in:

Angewandte Chemie, 2013, v. 125, n. 10, p. 3083, doi. 10.1002/ange.201204690

By:

Gersch, Malte;
Gut, Felix;
Korotkov, Vadim S.;
Lehmann, Johannes;
Böttcher, Thomas;
Rusch, Marion;
Hedberg, Christian;
Waldmann, Herbert;
Klebe, Gerhard;
Sieber, Stephan A.

Publication type:

Article

Identifizierung der Zielproteine bioaktiver Verbindungen: Die Suche nach der Nadel im Heuhaufen.

Published in:

Angewandte Chemie, 2013, v. 125, n. 10, p. 2808, doi. 10.1002/ange.201208749

By:

Ziegler, Slava;
Pries, Verena;
Hedberg, Christian;
Waldmann, Herbert

Publication type:

Article

A Natural Product Inspired Tetrahydropyran Collection Yields Mitosis Modulators that Synergistically Target CSE1L and Tubulin.

Published in:

Angewandte Chemie, 2013, v. 125, n. 1, p. 428, doi. 10.1002/ange.201205728

By:

Voigt, Tobias;
Gerding ‐ Reimers, Claas;
Ngoc Tran, Tuyen Thi;
Bergmann, Sabrina;
Lachance, Hugo;
Schölermann, Beate;
Brockmeyer, Andreas;
Janning, Petra;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Highly Enantioselective Catalytic [6+3] Cycloadditions of Azomethine Ylides.

Published in:

Angewandte Chemie, 2012, v. 124, n. 38, p. 9650, doi. 10.1002/ange.201204394

By:

Potowski, Marco;
Bauer, Jonathan O.;
Strohmann, Carsten;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Editorial: Wirkstoffforschung ...︁. der Dritte im Bunde!

Published in:

Angewandte Chemie, 2012, v. 124, n. 26, p. 6388, doi. 10.1002/ange.201201102

By:

Waldmann, Herbert

Publication type:

Article

Biologie-orientierte Synthese (BIOS).

Published in:

Angewandte Chemie, 2011, v. 123, n. 46, p. 10990, doi. 10.1002/ange.201007004

By:

Wetzel, Stefan;
Bon, Robin S.;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M.

Published in:

Angewandte Chemie, 2011, v. 123, n. 42, p. 10012, doi. 10.1002/ange.201102967

By:

Rusch, Marion;
Zimmermann, Tobias J.;
Bürger, Marco;
Dekker, Frank J.;
Görmer, Kristina;
Triola, Gemma;
Brockmeyer, Andreas;
Janning, Petra;
Böttcher, Thomas;
Sieber, Stephan A.;
Vetter, Ingrid R.;
Hedberg, Christian;
Waldmann, Herbert

Publication type:

Article

Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design.

Published in:

Angewandte Chemie, 2011, v. 123, n. 42, p. 10006, doi. 10.1002/ange.201102965

By:

Hedberg, Christian;
Dekker, Frank J.;
Rusch, Marion;
Renner, Steffen;
Wetzel, Stefan;
Vartak, Nachiket;
Gerding-Reimers, Claas;
Bon, Robin S.;
Bastiaens, Philippe I. H.;
Waldmann, Herbert

Publication type:

Article

Gold(I)-Catalyzed Synthesis of Benzoxocines by an 8- endo-dig Cyclization.

Published in:

Angewandte Chemie, 2011, v. 123, n. 39, p. 9242, doi. 10.1002/ange.201103832

By:

Wittstein, Kathrin;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Die Pictet-Spengler-Reaktion in der Natur und der organischen Chemie.

Published in:

Angewandte Chemie, 2011, v. 123, n. 37, p. 8692, doi. 10.1002/ange.201008071

By:

Stöckigt, Joachim;
Antonchick, Andrey P.;
Wu, Fangrui;
Waldmann, Herbert

Publication type:

Article

One-Pot Dual-Labeling of a Protein by Two Chemoselective Reactions.

Published in:

Angewandte Chemie, 2011, v. 123, n. 36, p. 8437, doi. 10.1002/ange.201100840

By:

Yi, Long;
Sun, Hongyan;
Itzen, Aymelt;
Triola, Gemma;
Waldmann, Herbert;
Goody, Roger S.;
Wu, Yao-Wen

Publication type:

Article

Structure-Guided Development of Selective RabGGTase Inhibitors.

Published in:

Angewandte Chemie, 2011, v. 123, n. 21, p. 5059, doi. 10.1002/ange.201101210

By:

Bon, Robin S.;
Guo, Zhong;
Stigter, E. Anouk;
Wetzel, Stefan;
Menninger, Sascha;
Wolf, Alexander;
Choidas, Axel;
Alexandrov, Kirill;
Blankenfeldt, Wulf;
Goody, Roger S.;
Waldmann, Herbert

Publication type:

Article

Total Synthesis and Biological Evaluation of (−)-Englerin A and B: Synthesis of Analogues with Improved Activity Profile.

Published in:

Angewandte Chemie, 2011, v. 123, n. 17, p. 4084, doi. 10.1002/ange.201007790

By:

Radtke, Lea;
Willot, Matthieu;
Sun, Hongyan;
Ziegler, Slava;
Sauerland, Stephanie;
Strohmann, Carsten;
Fröhlich, Roland;
Habenberger, Peter;
Waldmann, Herbert;
Christmann, Mathias

Publication type:

Article

Discovery of a Novel Pseudo‐Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling.

Published in:

Advanced Science, 2024, v. 11, n. 21, p. 1, doi. 10.1002/advs.202309202

By:

Wang, Lin;
Yilmaz, Furkan;
Yildirim, Okan;
Schölermann, Beate;
Bag, Sukdev;
Greiner, Luca;
Pahl, Axel;
Sievers, Sonja;
Scheel, Rebecca;
Strohmann, Carsten;
Squire, Christopher;
Foley, Daniel J.;
Ziegler, Slava;
Grigalunas, Michael;
Waldmann, Herbert

Publication type:

Article

Gold(I)‐Catalyzed and Nucleophile‐Guided Ligand‐Directed Divergent Synthesis.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 41, p. 5688, doi. 10.1002/ejoc.201801080

By:

Lee, Yen‐Chun;
Knauer, Lena;
Louven, Kathrin;
Golz, Christopher;
Strohmann, Carsten;
Waldmann, Herbert;
Kumar, Kamal

Publication type:

Article

Oriented Immobilization of Farnesylated Proteins by the Thiol-Ene Reaction.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 7, p. 1252, doi. 10.1002/anie.200906190

By:

Weinrich, Dirk;
Lin, Po-Chiao;
Jonkheijm, Pascal;
Nguyen, Uyen T. T.;
Schröder, Hendrik;
Niemeyer, Christof M.;
Alexandrov, Kirill;
Goody, Roger;
Waldmann, Herbert

Publication type:

Article

The Lipid Modifications of Ras that Sense Membrane Environments and Induce Local Enrichment.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 46, p. 8784, doi. 10.1002/anie.200903396

By:

Vogel, Alexander;
Reuther, Guido;
Weise, Katrin;
Triola, Gemma;
Nikolaus, Jörg;
Tan, Kui-Thong;
Nowak, Christine;
Herrmann, Andreas;
Waldmann, Herbert;
Winter, Roland;
Huster, Daniel

Publication type:

Article

Tumor-Associated MUC1 Tandem-Repeat Glycopeptide Microarrays to Evaluate Serum- and Monoclonal-Antibody Specificity.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 44, p. 8263, doi. 10.1002/anie.200902963

By:

Westerlind, Ulrika;
Schröder, Hendrik;
Hobel, Alexandra;
Gaidzik, Nikola;
Kaiser, Anton;
Niemeyer, Christof M.;
Schmitt, Edgar;
Waldmann, Herbert;
Kunz, Horst

Publication type:

Article

Cover Picture: Tumor-Associated MUC1 Tandem-Repeat Glycopeptide Microarrays to Evaluate Serum- and Monoclonal-Antibody Specificity (Angew. Chem. Int. Ed. 44/2009).

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 44, p. 8151, doi. 10.1002/anie.200904924

By:

Westerlind, Ulrika;
Schröder, Hendrik;
Hobel, Alexandra;
Gaidzik, Nikola;
Kaiser, Anton;
Niemeyer, Christof M.;
Schmitt, Edgar;
Waldmann, Herbert;
Kunz, Horst

Publication type:

Article

Applications of Protein Biochips in Biomedical and Biotechnological Research.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 42, p. 7744, doi. 10.1002/anie.200901480

By:

Weinrich, Dirk;
Jonkheijm, Pascal;
Niemeyer, Christof M.;
Waldmann, Herbert

Publication type:

Article

The Ras Pathway Modulator Melophlin A Targets Dynamins.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 39, p. 7240, doi. 10.1002/anie.200902023

By:

Knoth, Tanja;
Warburg, Karin;
Katzka, Catherine;
Rai, Amrita;
Wolf, Alexander;
Brockmeyer, Andreas;
Janning, Petra;
Reubold, Thomas F.;
Eschenburg, Susanne;
Manstein, Dietmar J.;
Hübel, Katja;
Kaiser, Markus;
Waldmann, Herbert

Publication type:

Article

Synthesis of Natural Product Inspired Compound Collections.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 18, p. 3224, doi. 10.1002/anie.200803437

By:

Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Development of Tau Aggregation Inhibitors for Alzheimer's Disease.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 10, p. 1740, doi. 10.1002/anie.200802621

By:

Bulic, Bruno;
Pickhardt, Marcus;
Schmidt, Boris;
Mandelkow, Eva-Maria;
Waldmann, Herbert;
Mandelkow, Eckhard

Publication type:

Article

Total Synthesis of Chondramide C and Its Binding Mode to F-Actin.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 9, p. 1526, doi. 10.1002/anie.200990037

By:

Waldmann, Herbert;
Hu, Tai-Shan;
Renner, Steffen;
Menninger, Sascha;
Tannert, René;
Oda, Toshiro;
Arndt, Hans-Dieter

Publication type:

Article