Works by Wakim, Linda M.

Results: 26

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus.

Published in:

Nature Immunology, 2009, v. 10, n. 5, p. 524, doi. 10.1038/ni.1718

By:

Gebhardt, Thomas;
Wakim, Linda M;
Eidsmo, Liv;
Reading, Patrick C;
Heath, William R;
Carbone, Francis R

Publication type:

Article

Staphylococcal superantigens evoke temporary and reversible T cell anergy, but fail to block the development of a bacterium specific cellular immune response.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54074-8

By:

Zhang, Heran;
Monk, Ian R.;
Braverman, Jessica;
Jones, Claerwen M.;
Brooks, Andrew G.;
Stinear, Timothy P.;
Wakim, Linda M.

Publication type:

Article

Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.

Published in:

2018

By:

Pizzolla, Angela;
Nguyen, Thi Ho;
Sant, Sneha;
Jaffar, Jade;
Loudovaris, Tom;
Mannering, Stuart I;
Thomas, Paul G;
Westall, Glen P;
Kedzierska, Katherine;
Wakim, Linda M

Publication type:

journal article

Intranasal Delivery of a Chitosan-Hydrogel Vaccine Generates Nasal Tissue Resident Memory CD8 + T Cells That Are Protective against Influenza Virus Infection.

Published in:

Vaccines, 2020, v. 8, n. 4, p. 572, doi. 10.3390/vaccines8040572

By:

Bedford, James G.;
Caminschi, Irina;
Wakim, Linda M.

Publication type:

Article

Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine.

Published in:

Vaccines, 2018, v. 6, n. 2, p. 18, doi. 10.3390/vaccines6020018

By:

Clemens, E. Bridie;
van de Sandt, Carolien;
Wong, Sook San;
Wakim, Linda M.;
Valkenburg, Sophie A.

Publication type:

Article

Neutrophils play an ongoing role in preventing bacterial pneumonia by blocking the dissemination of Staphylococcus aureus from the upper to the lower airways.

Published in:

Immunology & Cell Biology, 2020, v. 98, n. 7, p. 577, doi. 10.1111/imcb.12343

By:

Ge, Chenghao;
Monk, Ian R;
Monard, Sarah C;
Bedford, James G;
Braverman, Jessica;
Stinear, Timothy P;
Wakim, Linda M

Publication type:

Article

When input does not match output, lung-resident memory T cells decay.

Published in:

Immunology & Cell Biology, 2017, v. 95, n. 4, p. 321, doi. 10.1038/icb.2017.14

By:

Wakim, Linda M

Publication type:

Article

Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01453

By:

Sant, Sneha;
Grzelak, Ludivine;
Wang, Zhongfang;
Pizzolla, Angela;
Koutsakos, Marios;
Crowe, Jane;
Loudovaris, Thomas;
Mannering, Stuart I.;
Westall, Glen P.;
Wakim, Linda M.;
Rossjohn, Jamie;
Gras, Stephanie;
Richards, Michael;
Xu, Jianqing;
Thomas, Paul G.;
Loh, Liyen;
Nguyen, Thi H. O.;
Kedzierska, Katherine

Publication type:

Article

Influenza, but not SARS‐CoV‐2, infection induces a rapid interferon response that wanes with age and diminished tissue‐resident memory CD8+ T cells.

Published in:

Clinical & Translational Immunology, 2021, v. 10, n. 1, p. 1, doi. 10.1002/cti2.1242

By:

Nguyen, Thi HO;
McAuley, Julie L;
Kim, Youry;
Zheng, Ming ZM;
Gherardin, Nicholas A;
Godfrey, Dale I;
Purcell, Damian FJ;
Sullivan, Lucy C;
Westall, Glen P;
Reading, Patrick C;
Kedzierska, Katherine;
Wakim, Linda M

Publication type:

Article

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.63452

By:

Tullett, Kirsteen M.;
Tan, Peck Szee;
Hae-Young Park;
Schittenhelm, Ralf B.;
Michael, Nicole;
Rong Li;
Policheni, Antonia N.;
Gruber, Emily;
Cheng Huang;
Fulcher, Alex J.;
Danne, Jillian C.;
Czabotar, Peter E.;
Wakim, Linda M.;
Mintern, Justine D.;
Ramm, Georg;
Radford, Kristen J.;
Caminschi, Irina;
O'Keeffe, Meredith;
Villadangos, Jose A.;
Wright, Mark D.

Publication type:

Article

Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity.

Published in:

Science Translational Medicine, 2018, v. 10, n. 428, p. 1, doi. 10.1126/scitranslmed.aan8405

By:

Koutsakos, Marios;
Wheatley, Adam K.;
Loh, Liyen;
Clemens, E. Bridie;
Sant, Sneha;
Nüssing, Simone;
Fox, Annette;
Chung, Amy W.;
Laurie, Karen L.;
Hurt, Aeron C.;
Rockman, Steve;
Lappas, Martha;
Loudovaris, Thomas;
Mannering, Stuart I.;
Westall, Glen P.;
Elliot, Michael;
Tangye, Stuart G.;
Wakim, Linda M.;
Kent, Stephen J.;
Nguyen, Thi H. O.

Publication type:

Article

CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47576-y

By:

Menon, Tejas;
Illing, Patricia T.;
Chaurasia, Priyanka;
McQuilten, Hayley A.;
Shepherd, Chloe;
Rowntree, Louise C.;
Petersen, Jan;
Littler, Dene R.;
Khuu, Grace;
Ziyi Huang;
Allen, Lilith F.;
Rockman, Steve;
Crowe, Jane;
Flanagan, Katie L.;
Wakim, Linda M.;
Nguyen, Thi H. O.;
Mifsud, Nicole A.;
Rossjohn, Jamie;
Purcell, Anthony W.;
van de Sandt, Carolien E.

Publication type:

Article

Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46822-7

By:

Foo, Isabelle Jia-Hui;
Chua, Brendon Y.;
Clemens, E. Bridie;
So Young Chang;
Xiaoxiao Jia;
McQuilten, Hayley A.;
Yiing Yap, Ashley Huey;
Cabug, Aira F.;
Ashayeripanah, Mitra;
McWilliam, Hamish E. G.;
Villadangos, Jose A.;
Evrard, Maximilien;
Mackay, Laura K.;
Wakim, Linda M.;
Fazakerley, John K.;
Kedzierska, Katherine;
Kedzierski, Lukasz

Publication type:

Article

Enhanced survival of lung tissue-resident memory CD8+ T cells during infection with influenza virus due to selective expression of IFITM3.

Published in:

Nature Immunology, 2013, v. 14, n. 3, p. 238, doi. 10.1038/ni.2525

By:

Wakim, Linda M;
Gupta, Nishma;
Mintern, Justine D;
Villadangos, Jose A

Publication type:

Article

Polyclonal but not monoclonal circulating memory CD4+ T cells attenuate the severity of Staphylococcus aureus bacteremia.

Published in:

Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1417220

By:

Braverman, Jessica;
Monk, Ian R.;
Zhang, Heran;
Stinear, Timothy P.;
Wakim, Linda M.

Publication type:

Article

Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210132

By:

Bedford, James G.;
O’Keeffe, Meredith;
Reading, Patrick C.;
Wakim, Linda M.

Publication type:

Article

Vaccine-induced inflammation and inflammatory monocytes promote CD4+ T cell-dependent immunity against murine salmonellosis.

Published in:

PLoS Pathogens, 2023, v. 19, n. 9, p. 1, doi. 10.1371/journal.ppat.1011666

By:

Wang, Nancy;
Scott, Timothy A.;
Kupz, Andreas;
Shreenivas, Meghanashree M.;
Peres, Newton G.;
Hocking, Dianna M.;
Yang, Chenying;
Jebeli, Leila;
Beattie, Lynette;
Groom, Joanna R.;
Pierce, Thomas P.;
Wakim, Linda M.;
Bedoui, Sammy;
Strugnell, Richard A.

Publication type:

Article

Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes.

Published in:

Science Immunology, 2020, v. 5, n. 52, p. 1, doi. 10.1126/sciimmunol.abb5439

By:

Bedford, James G.;
Heinlein, Melanie;
Garnham, Alexandra L.;
Nguyen, Thi H. O.;
Loudovaris, Tom;
Ge, Chenghao;
Mannering, Stuart I.;
Elliott, Michael;
Tangye, Stuart G.;
Kedzierska, Katherine;
Gray, Daniel H. D.;
Heath, William R.;
Wakim, Linda M.

Publication type:

Article

Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

Published in:

Science Immunology, 2017, v. 2, n. 12, p. 1, doi. 10.1126/sciimmunol.aam6970

By:

Pizzolla, Angela;
O. Nguyen, Thi H.;
Smith, Jeffrey M.;
Brooks, Andrew G.;
Kedzieska, Katherine;
Heath, William R.;
Reading, Patrick C.;
Wakim, Linda M.

Publication type:

Article

Intranasal Epitope‐Polymer Vaccine Lodges Resident Memory T Cells Protecting Against Influenza Virus.

Published in:

Advanced Healthcare Materials, 2024, v. 13, n. 15, p. 1, doi. 10.1002/adhm.202304188

By:

Liu, Ziyang;
Kabir, Md. Tanvir;
Chen, Shuxiong;
Zhang, Heran;
Wakim, Linda M.;
Rehm, Bernd H. A.

Publication type:

Article

Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8+ T Cell Priming.

Published in:

PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0143539

By:

Infusini, Giuseppe;
Smith, Jeffrey M.;
Yuan, He;
Pizzolla, Angela;
Ng, Wy Ching;
Londrigan, Sarah L.;
Haque, Ashraful;
Reading, Patrick C.;
Villadangos, Jose A.;
Wakim, Linda M.

Publication type:

Article

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142925

By:

Londrigan, Sarah L.;
Tate, Michelle D.;
Job, Emma R.;
Moffat, Jessica M.;
Wakim, Linda M.;
Gonelli, Christopher A.;
Purcell, Damien F. J.;
Brooks, Andrew G.;
Villadangos, Jose A.;
Reading, Patrick C.;
Mintern, Justine D.

Publication type:

Article

Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection.

Published in:

Nature, 2011, v. 471, n. 7340, p. 629, doi. 10.1038/nature09863

By:

Wakim, Linda M.;
Bevan, Michael J.

Publication type:

Article

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response.

Published in:

Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00887

By:

Bedford, James G.;
Infusini, Giuseppe;
Dagley, Laura F.;
Villalon-Letelier, Fernando;
Zheng, Ming Z. M.;
Bennett-Wood, Vicki;
Reading, Patrick C.;
Wakim, Linda M.

Publication type:

Article

CD8+ T-cell attenuation of cutaneous herpes simplex virus infection reduces the average viral copy number of the ensuing latent infection.

Published in:

Immunology & Cell Biology, 2008, v. 86, n. 8, p. 666, doi. 10.1038/icb.2008.47

By:

Wakim, Linda M.;
Jones, Claerwen M.;
Gebhardt, Thomas;
Preston, Christopher M.;
Carbone, Francis R.

Publication type:

Article

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10661-8

By:

Wu, Ting;
Guan, Jing;
Handel, Andreas;
Tscharke, David C.;
Sidney, John;
Sette, Alessandro;
Wakim, Linda M.;
Sng, Xavier Y. X.;
Thomas, Paul G.;
Croft, Nathan P.;
Purcell, Anthony W.;
La Gruta, Nicole L.

Publication type:

Article

Works by Wakim, Linda M.

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus.

Staphylococcal superantigens evoke temporary and reversible T cell anergy, but fail to block the development of a bacterium specific cellular immune response.

Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.

Intranasal Delivery of a Chitosan-Hydrogel Vaccine Generates Nasal Tissue Resident Memory CD8 + T Cells That Are Protective against Influenza Virus Infection.

Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine.

Neutrophils play an ongoing role in preventing bacterial pneumonia by blocking the dissemination of Staphylococcus aureus from the upper to the lower airways.

When input does not match output, lung-resident memory T cells decay.

Single-Cell Approach to Influenza-Specific CD8<sup>+</sup> T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

Influenza, but not SARS‐CoV‐2, infection induces a rapid interferon response that wanes with age and diminished tissue‐resident memory CD8<sup>+</sup> T cells.

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells.

Circulating T<sub>FH</sub> cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity.

CD8<sup>+</sup> T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age.

Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses.

Enhanced survival of lung tissue-resident memory CD8<sup>+</sup> T cells during infection with influenza virus due to selective expression of IFITM3.

Polyclonal but not monoclonal circulating memory CD4<sup>+</sup> T cells attenuate the severity of Staphylococcus aureus bacteremia.

Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection.

Vaccine-induced inflammation and inflammatory monocytes promote CD4<sup>+</sup> T cell-dependent immunity against murine salmonellosis.

Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes.

Resident memory CD8<sup>+</sup> T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

Intranasal Epitope‐Polymer Vaccine Lodges Resident Memory T Cells Protecting Against Influenza Virus.

Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8<sup>+</sup> T Cell Priming.

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection.

Cross-dressed dendritic cells drive memory CD8<sup>+</sup> T-cell activation after viral infection.

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response.

CD8<sup>+</sup> T-cell attenuation of cutaneous herpes simplex virus infection reduces the average viral copy number of the ensuing latent infection.

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.