Works by Wakefield, Lalage M

Results: 30

Synergistic antitumor effects of a TGF? inhibitor and cyclophosphamide.

Published in:

OncoImmunology, 2014, v. 3, n. 4, p. N.PAG, doi. 10.4161/onci.28247

By:

Chen, Xin;
Wakefield, Lalage M;
Oppenheim, Joost J

Publication type:

Article

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein.

Published in:

Cell Death & Disease, 2019, v. 10, n. 10, p. N.PAG, doi. 10.1038/s41419-019-1892-7

By:

Byun, Jung S.;
Park, Samson;
Yi, Dae Ik;
Shin, Jee-Hye;
Hernandez, Sara Gil;
Hewitt, Stephen M.;
Nicklaus, Marc C.;
Peach, Megan L.;
Guasch, Laura;
Tang, Binwu;
Wakefield, Lalage M.;
Yan, Tingfen;
Caban, Ambar;
Jones, Alana;
Kabbout, Mohamed;
Vohra, Nasreen;
Nápoles, Anna María;
Singhal, Sandeep;
Yancey, Ryan;
De Siervi, Adriana

Publication type:

Article

TGF-β modulates the functionality of tumor-infiltrating CD8<sup>+</sup> T cells through effects on TCR signaling and Spred1 expression.

Published in:

Cancer Immunology, Immunotherapy, 2009, v. 58, n. 11, p. 1811, doi. 10.1007/s00262-009-0692-9

By:

di Bari, Maria Giovanna;
Lutsiak, M. E. Christine;
Takai, Shinji;
Mostböck, Sven;
Farsaci, Benedetto;
Semnani, Roshanak Tolouei;
Wakefield, Lalage M.;
Schlom, Jeffrey;
Sabzevari, Helen

Publication type:

Article

Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0126483

By:

Sato, Misako;
Matsubara, Tsutomu;
Adachi, Jun;
Hashimoto, Yuuki;
Fukamizu, Kazuna;
Kishida, Marina;
Yang, Yu-an;
Wakefield, Lalage M.;
Tomonaga, Takeshi

Publication type:

Article

Effective Chemoimmunotherapy with Anti-TGFβ Antibody and Cyclophosphamide in a Mouse Model of Breast Cancer.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085398

By:

Chen, Xin;
Yang, Yuan;
Zhou, Qiong;
Weiss, Jonathan M.;
Howard, OlaMae Zack;
McPherson, John M.;
Wakefield, Lalage M.;
Oppenheim, Joost J.

Publication type:

Article

Expression of the B-Cell Receptor Component CD79a on Immature Myeloid Cells Contributes to Their Tumor Promoting Effects.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076115

By:

Luger, Dror;
Yang, Yu-an;
Raviv, Asaf;
Weinberg, Douglas;
Banerjee, Subhadra;
Lee, Min-Jung;
Trepel, Jane;
Yang, Li;
Wakefield, Lalage M.

Publication type:

Article

Genetic Background May Contribute to PAM50 Gene Expression Breast Cancer Subtype Assignments.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072287

By:

Hu, Ying;
Bai, Ling;
Geiger, Thomas;
Goldberger, Natalie;
Walker, Renard C.;
Green, Jeffery E.;
Wakefield, Lalage M.;
Hunter, Kent W.

Publication type:

Article

SDF-1α Mediates Wound-Promoted Tumor Growth in a Syngeneic Orthotopic Mouse Model of Breast Cancer.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060919

By:

Stuelten, Christina H.;
Cervoni-Curet, Frances N.;
Busch, Johanna I.;
Sutton, Emily;
Webster, Joshua D.;
Kavalukas, Sandra L.;
Wakefield, Lalage M.;
Barbul, Adrian;
Niederhuber, John E.

Publication type:

Article

Transient Tumor-Fibroblast Interactions Increase Tumor Cell Malignancy by a TGF-β Mediated Mechanism in a Mouse Xenograft Model of Breast Cancer.

Published in:

PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009832

By:

Stuelten, Christina H.;
Busch, Johanna I.;
Binwu Tang;
Flanders, Kathleen C.;
Oshima, Akira;
Sutton, Emily;
Karpova, Tatiana S.;
Roberts, Anita B.;
Wakefield, Lalage M.;
Niederhuber, John E.

Publication type:

Article

Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines.

Published in:

PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009201

By:

Kadota, Mitsutaka;
Yang, Howard H.;
Gomez, Bianca;
Sato, Misako;
Clifford, Robert J.;
Meerzaman, Daoud;
Dunn, Barbara K.;
Wakefield, Lalage M.;
Lee, Maxwell P.

Publication type:

Article

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.

Published in:

2017

By:

Keysar, Stephen B.;
Le, Phuong N.;
Miller, Bettina;
Jackson, Brian C.;
Eagles, Justin R.;
Nieto, Cera;
Jihye Kim;
Binwu Tang;
Glogowska, Magdalena J.;
Morton, J. Jason;
Padilla-Just, Nuria;
Gomez, Karina;
Warnock, Emily;
Reisinger, Julie;
Arcaroli, John J.;
Messersmith, Wells A.;
Wakefield, Lalage M.;
Dexiang Gao;
Aik-Choon Tan;
Serracino, Hilary

Publication type:

journal article

Translational Control Elements in the Major Human Transforming Growth Factor-β1 mRNA.

Published in:

Growth Factors, 1998, v. 16, n. 2, p. 89, doi. 10.3109/08977199809002120

By:

Allison, Robin S.H.;
Mumy, Michelle L.;
Wakefield, Lalage M.

Publication type:

Article

Addition of a C-Terminal Extension Sequence to Transforming Growth Factor-pl Interferes with Biosynthetic Processing and Abolishes Biological Activity.

Published in:

Growth Factors, 1991, v. 5, n. 3, p. 243, doi. 10.3109/08977199109000288

By:

Wakefield, Lalage M.;
Kondaiah, Paturu;
Hollands, Robin S.;
Winokur, Thomas S.;
Sporn, Michael B.

Publication type:

Article

Recombinant TGF-β1 is Synthesized as a Two-Component Latent Complex that Shares Some Structural Features with the Native Platelet Latent TGF-β1 Complex.

Published in:

Growth Factors, 1989, v. 1, n. 3, p. 203, doi. 10.3109/08977198908997997

By:

Wakefield, Lalage M.;
Smith, Diane M.;
Broz, Susan;
Jackson, Mark;
Levinson, Arthur D.;
Sporn, Michael B.

Publication type:

Article

Modeling metastasis biology and therapy in real time in the mouse lung.

Published in:

2010

By:

Mendoza, Arnulfo;
Sung-Hyeok Hong;
Osborne, Tanasa;
Khan, Mohammed A.;
Campbell, Kirk;
Briggs, Joseph;
Eleswarapu, Ananth;
Buquo, Lauren;
Ren, Ling;
Hewitt, Stephen M.;
Dakir, El-H.;
Garfield, Susan;
Walker, Renard;
Merlino, Glenn;
Green, Jeffrey E.;
Hunter, Kent W.;
Wakefield, Lalage M.;
Khanna, Chand;
Hong, Sung-Hyeok;
Dakir, El Habib

Publication type:

journal article

Capillary nano-immunoassays: advancing quantitative proteomics analysis, biomarker assessment, and molecular diagnostics.

Published in:

Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0537-6

By:

Jin-Qiu Chen;
Wakefield, Lalage M.;
Goldstein, David J.

Publication type:

Article

Capillary nano-immunoassays: advancing quantitative proteomics analysis, biomarker assessment, and molecular diagnostics.

Published in:

2015

By:

Chen, Jin-Qiu;
Wakefield, Lalage M;
Goldstein, David J

Publication type:

journal article

A p21-ZEB1 Complex Inhibits Epithelial-Mesenchymal Transition through the MicroRNA 183-96-182 Cluster.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 3, p. 533, doi. 10.1128/MCB.01043-13

By:

Xiao Ling Li;
Toshifumi Hara;
Youngeun Choi;
Subramanian, Murugan;
Francis, Princy;
Bilke, Sven;
Walker, Robert L.;
Pineda, Marbin;
Yuelin Zhu;
Yuan Yang;
Ji Luo;
Wakefield, Lalage M.;
Brabletz, Thomas;
Park, Ben Ho;
Sharma, Sudha;
Chowdhury, Dipanjan;
Meltzer, Paul S.;
Lal, Ashish

Publication type:

Article

The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting‡.

Published in:

Oncogene, 2000, v. 19, n. 8, p. 968, doi. 10.1038/sj.onc.1203277

By:

Cardiff, Robert D;
Anver, Miriam R;
Gusterson, Barry A;
Hennighausen, Lothar;
Jensen, Roy A;
Merino, Maria J;
Rehm, Sabine;
Russo, Jose;
Tavassoli, Fattaneh A;
Wakefield, Lalage M;
Ward, Jerrold M;
Green, Jeffrey E

Publication type:

Article

Expression of a dominant-negative mutant TGF-ß type II receptor in transgenic mice reveals essential roles for TGF-ß in regulation of growth and differentiation in the exocrine pancreas.

Published in:

EMBO Journal, 1997, v. 16, n. 10, p. 2621, doi. 10.1093/emboj/16.10.2621

By:

Bottinger, Erwin P.;
Jakubczak, John L.;
Roberts, Ian S.;
Mumy, Michelle;
Hemmati, Philipp;
Bagnall, Kerri;
Merlino, Glenn;
Wakefield, Lalage M.

Publication type:

Article

Inhibition of the chondrocyte phenotype by retinoic acid involves upregulation of metalloprotease genes independent of TGF-β.

Published in:

Journal of Cellular Physiology, 1994, v. 159, n. 2, p. 340, doi. 10.1002/jcp.1041590217

By:

Ballock, R. Tracy;
Heydemann, Ahlke;
Wakefield, Lalage M.;
Flanders, Kathleen C.;
Roberts, Anita B.;
Sporn, Michael B.

Publication type:

Article

Beyond TGFβ: roles of other TGFβ superfamily members in cancer.

Published in:

2013

By:

Wakefield, Lalage M;
Hill, Caroline S

Publication type:

journal article

Beyond TGFβ: roles of other TGFβ superfamily members in cancer.

Published in:

Nature Reviews Cancer, 2013, v. 13, n. 5, p. 328, doi. 10.1038/nrc3500

By:

Wakefield, Lalage M.;
Hill, Caroline S.

Publication type:

Article

Immune-mediated pathology in Duchenne muscular dystrophy.

Published in:

Science Translational Medicine, 2015, v. 7, n. 299, p. 1, doi. 10.1126/scitranslmed.aaa7322

By:

Rosenberg, Amy S.;
Puig, Montserrat;
Nagaraju, Kanneboyina;
Hoffman, Eric P.;
Villalta, S. Armando;
Rao, V. Ashutosh;
Wakefield, Lalage M.;
Woodcock, Janet

Publication type:

Article

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer.

Published in:

Breast Cancer Research, 2014, v. 16, n. 3, p. 1, doi. 10.1186/bcr3668

By:

Sato, Misako;
Kadota, Mitsutaka;
Tang, Binwu;
Yang, Howard H.;
Yang, Yu-an;
Weng, Mengge;
Weng, Jia;
Welsh, Michael A.;
Flanders, Kathleen C.;
Nagano, Yoshiko;
Michalowski, Aleksandra M.;
Clifford, Robert J.;
Lee, Maxwell P.;
Wakefield, Lalage M.

Publication type:

Article

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer.

Published in:

2014

By:

Sato, Misako;
Kadota, Mitsutaka;
Tang, Binwu;
Yang, Howard H;
Yang, Yu-An;
Shan, Mengge;
Weng, Jia;
Welsh, Michael A;
Flanders, Kathleen C;
Nagano, Yoshiko;
Michalowski, Aleksandra M;
Clifford, Robert J;
Lee, Maxwell P;
Wakefield, Lalage M

Publication type:

journal article

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10102-6

By:

Malik, Navdeep;
Yan, Hualong;
Moshkovich, Nellie;
Palangat, Murali;
Yang, Howard;
Sanchez, Vanesa;
Cai, Zhuo;
Peat, Tyler J.;
Jiang, Shunlin;
Liu, Chengyu;
Lee, Maxwell;
Mock, Beverly A.;
Yuspa, Stuart H.;
Larson, Daniel;
Wakefield, Lalage M.;
Huang, Jing

Publication type:

Article

Enhanced tumorigenesis and reduced transforming growth factor-β type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-β1.

Published in:

Molecular Carcinogenesis, 2000, v. 29, n. 2, p. 112, doi. 10.1002/1098-2744(200010)29:2<112::AID-MC8>3.0.CO;2-9

By:

Kang, Yang;
Mariano, Jennifer M.;
Angdisen, Jerry;
Moody, Terry W.;
Diwan, Bhalchandra A.;
Wakefield, Lalage M.;
Jakowlew, Sonia B.

Publication type:

Article

Transforming Growth Factor-β: Multifunctional Regulator of Cell Growth and Phenotype.

Published in:

Annals of the New York Academy of Sciences, 1988, v. 551, n. 1, p. 290, doi. 10.1111/j.1749-6632.1988.tb22355.x

By:

WAKEFIELD, LALAGE M.;
THOMPSON, NANCY L.;
FLANDERS, KATHLEEN C.;
O'CONNOR-McCOURT, MAUREEN D.;
SPORN, MICHAEL B.

Publication type:

Article

TRANSFORMING GROWTH FACTOR-b1 AND ITS RECEPTORS IN HUMAN LUNG CANCER AND MOUSE LUNG CARCINOGENESIS.

Published in:

Experimental Lung Research, 2000, v. 26, n. 8, p. 685, doi. 10.1080/01902140150216765

By:

Kang, Yang;
Prentice, Margaret A.;
Mariano, Jennifer M.;
Davarya, Shekar;
Linnoila, R. Ilona;
Moody, Terry W.;
Wakefield, Lalage M.;
Jakowlew, Sonia B.

Publication type:

Article