Works matching AU Wainer, Irving W.

Results: 79

Allosteric modifiers of neuronal nicotinic acetylcholine receptors: New methods, new opportunities.

Published in:

Medicinal Research Reviews, 2007, v. 27, n. 5, p. 723, doi. 10.1002/med.20091

By:

Moaddel, Ruin;
Jozwiak, Krzysztof;
Wainer, Irving W.

Publication type:

Article

Ketamine for Refractory Chronic Migraine: An Observational Pilot Study and Metabolite Analysis.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 11, p. 1421, doi. 10.1002/jcph.1920

By:

Schwenk, Eric S.;
Torjman, Marc C.;
Moaddel, Ruin;
Lovett, Jacqueline;
Katz, Daniel;
Denk, William;
Lauritsen, Clinton;
Silberstein, Stephen D.;
Wainer, Irving W.

Publication type:

Article

Correction to: Ketamine in the Past, Present, and Future: Mechanisms, Metabolites, and Toxicity.

Published in:

2021

By:

Schwenk, Eric S.;
Pradhan, Basant;
Nalamasu, Rohit;
Stolle, Lucas;
Wainer, Irving W.;
Cirullo, Michael;
Olson, Alexander;
Pergolizzi, Joseph V.;
Torjman, Marc C.;
Viscusi, Eugene R.

Publication type:

corrected article

Ketamine in the Past, Present, and Future: Mechanisms, Metabolites, and Toxicity.

Published in:

2021

By:

Schwenk, Eric S.;
Pradhan, Basant;
Nalamasu, Rohit;
Stolle, Lucas;
Wainer, Irving W.;
Cirullo, Michael;
Olsen, Alexander;
Pergolizzi, Joseph V.;
Torjman, Marc C.;
Viscusi, Eugene R.;
Olson, Alexander

Publication type:

journal article

The Stereoselective Sulfate Conjugation of 4′-Methoxyfenoterol Stereoisomers by Sulfotransferase Enzymes.

Published in:

Chirality, 2012, v. 24, n. 10, p. 796, doi. 10.1002/chir.22072

By:

Iyer, Lalitha V.;
Ramamoorthy, Anuradha;
Rutkowska, Ewelina;
Furimsky, Anna M.;
Tang, Liang;
Catz, Paul;
Green, Carol E.;
Jozwiak, Krzysztof;
Wainer, Irving W.

Publication type:

Article

Effect of fenoterol stereochemistry on the β2 adrenergic receptor system: Ligand-directed chiral recognition.

Published in:

Chirality, 2011, v. 23, n. 1E, p. E1, doi. 10.1002/chir.20963

By:

Jozwiak, Krzysztof;
Plazinska, Anita;
Toll, Lawrence;
Jimenez, Lucita;
Woo, Anthony Yiu-Ho;
Xiao, Rui-Ping;
Wainer, Irving W.

Publication type:

Article

Enantioselective pharmacokinetics of ( R)- and ( S)-ketamine after a 5-day infusion in patients with complex regional pain syndrome.

Published in:

Chirality, 2011, v. 23, n. 2, p. 138, doi. 10.1002/chir.20890

By:

Goldberg, Michael E.;
Torjman, Marc C.;
Schwartzman, Robert J.;
Mager, Donald E.;
Wainer, Irving W.

Publication type:

Article

Synthesis of tritium-labeled ( R, R)-4-methoxyfenoterol.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2010, v. 53, n. 2, p. 68, doi. 10.1002/jlcr.1703

By:

Kozocas, Joseph A.;
Bupp, James E.;
Tanga, Mary J.;
Pluhar, Joseph T.;
Wainer, Irving W.

Publication type:

Article

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07600-x

By:

Wnorowski, Artur;
Dudzik, Danuta;
Bernier, Michel;
Wójcik, Jakub;
Keijzers, Guido;
Diaz-Ruiz, Alberto;
Mazur, Karolina;
Zhang, Yongqing;
Han, Haiyong;
Scheibye-Knudsen, Morten;
Jozwiak, Krzysztof;
Barbas, Coral;
Wainer, Irving W.

Publication type:

Article

Interaction of ibogaine analogs with the nicotinic acetylcholine receptor.

Published in:

FASEB Journal, 2008, v. 22, p. 620, doi. 10.1096/fasebj.22.2_supplement.620

By:

Jozwiak, Krzysztof;
Moaddel, Ruin;
Wainer, Irving W.;
Arias, Hugo

Publication type:

Article

Development and characterization of the organic anion transporter column for on line studies of drug-transporter affinities.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1188, doi. 10.1096/fasebj.21.6.a1188-d

By:

Kimura, Tomoko;
Moaddel, Ruin;
Wainer, Irving W.

Publication type:

Article

Pharmacophore modeling of non transported competitive inhibitors of the human Organic Cation Transporter, hOCT1.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1187, doi. 10.1096/fasebj.21.6.a1187-b

By:

Moaddel, Ruin;
Ravichandran, Sarangan;
Bigi, Federica;
Collins, Jack;
Yamaguchi, Rika;
Wainer, Irving W.

Publication type:

Article

Enantioselective inhibition of d-serine transport by (S)-ketamine.

Published in:

2015

By:

Singh, Nagendra S;
Bernier, Michel;
Camandola, Simonetta;
Khadeer, Mohammed A;
Moaddel, Ruin;
Mattson, Mark P;
Wainer, Irving W

Publication type:

journal article

Receptor independent effects on DNA replication by steroids.

Published in:

Journal of Cellular Biochemistry, 1998, v. 70, n. 3, p. 323, doi. 10.1002/(SICI)1097-4644(19980901)70:3<323::AID-JCB5>3.0.CO;2-P

By:

Diaz-Perez, Maria J.;
Zannis-Hadjopoulos, Maria;
Price, Gerald B.;
Wainer, Irving W.

Publication type:

Article

Application of an in vitro system in the study of chemotherapeutic drug effects on DNA replication.

Published in:

Journal of Cellular Biochemistry, 1996, v. 61, n. 3, p. 444, doi. 10.1002/(SICI)1097-4644(19960601)61:3<444::AID-JCB11>3.0.CO;2-J

By:

Diaz-Perez, Maria J.;
Wainer, Irving W.;
Zannis-Hadjopoulos, Maria;
Price, Gerald B.

Publication type:

Article

GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts.

Published in:

International Journal of Cancer, 2017, v. 141, n. 10, p. 2131, doi. 10.1002/ijc.30904

By:

Bernier, Michel;
Catazaro, Jonathan;
Singh, Nagendra S.;
Wnorowski, Artur;
Boguszewska‐Czubara, Anna;
Jozwiak, Krzysztof;
Powers, Robert;
Wainer, Irving W.

Publication type:

Article

Finding time for allosteric interactions.

Published in:

Nature Biotechnology, 2004, v. 22, n. 11, p. 1376, doi. 10.1038/nbt1104-1376

By:

Wainer, Irving W.

Publication type:

Article

Removal of methotrexate, leucovorin, and their metabolites by combined hemodialysis and hemoperfusion.

Published in:

1988

By:

Relling, Mary V.;
Stapleton, F. Bruder;
Ochs, Judith;
Jones, Deborah P.;
Meyer, William;
Wainer, Irving W.;
Crom, William R.;
McKay, Charles P.;
Evans, William E.;
Relling, M V;
Stapleton, F B;
Ochs, J;
Jones, D P;
Meyer, W;
Wainer, I W;
Crom, W R;
McKay, C P;
Evans, W E

Publication type:

journal article

Observational study of the effect of ketamine infusions on sedation depth, inflammation, and clinical outcomes in mechanically ventilated patients with SARS-CoV-2.

Published in:

Anaesthesia & Intensive Care, 2024, v. 52, n. 2, p. 105, doi. 10.1177/0310057X231201184

By:

Wyler, David;
Torjman, Marc C;
Leong, Ron;
Baram, Michael;
Denk, William;
Long, Sara C;
Gawel, Richard J;
Viscusi, Eugene R;
Wainer, Irving W;
Schwenk, Eric S

Publication type:

Article

Author Correction: Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington's disease for participants of varying functional disability: a pilot study.

Published in:

2021

By:

McGarry, Andrew;
Gaughan, John;
Hackmyer, Cory;
Lovett, Jacqueline;
Khadeer, Mohammed;
Shaikh, Hamza;
Pradhan, Basant;
Ferraro, Thomas N.;
Wainer, Irving W.;
Moaddel, Ruin

Publication type:

Correction Notice

Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington's disease for participants of varying functional disability: a pilot study.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77526-9

By:

McGarry, Andrew;
Gaughan, John;
Hackmyer, Cory;
Lovett, Jacqueline;
Khadeer, Mohammed;
Shaikh, Hamza;
Pradhan, Basant;
Ferraro, Thomas N.;
Wainer, Irving W.;
Moaddel, Ruin

Publication type:

Article

In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil*.

Published in:

Clinical Pharmacology & Therapeutics, 1999, v. 66, n. 1, p. 40, doi. 10.1016/S0009-9236(99)70052-4

By:

Krecic-Shepard, Mary Ellen;
Barnas, Crissy R.;
Slimko, Jill;
Gorski, J. Christopher;
Wainer, Irving W.;
Schwartz, Janice B.

Publication type:

Article

What is hydroxynorketamine and what can it bring to neurotherapeutics?

Published in:

Expert Review of Neurotherapeutics, 2014, v. 14, n. 11, p. 1239, doi. 10.1586/14737175.2014.971760

By:

Singh, Nagendra S;
Zarate, Carlos A;
Moaddel, Ruin;
Bernier, Michel;
Wainer, Irving W

Publication type:

Article

The relationship between a urinary cachectic factor and weight loss in advanced cancer patients.

Published in:

2004

By:

Williams, M. L.;
Torres-Duarte, A.;
Brant, L. J.;
Bhargava, P.;
Marshall, J.;
Wainer, Irving W.

Publication type:

journal article

The distribution and clearance of (2S,6S)-hydroxynorketamine, an active ketamine metabolite, in Wistar rats.

Published in:

Pharmacology Research & Perspectives, 2015, v. 3, n. 4, p. n/a, doi. 10.1002/prp2.157

By:

Moaddel, Ruin;
Sanghvi, Mitesh;
Dossou, Katina Sourou Sylvestre;
Ramamoorthy, Anuradha;
Green, Carol;
Bupp, James;
Swezey, Robert;
O'Loughlin, Kathleen;
Wainer, Irving W.

Publication type:

Article

Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.

Published in:

British Journal of Clinical Pharmacology, 2012, v. 74, n. 2, p. 304, doi. 10.1111/j.1365-2125.2012.04198.x

By:

Zhao, Xiaochen;
Venkata, Swarajya Lakshmi Vattem;
Moaddel, Ruin;
Luckenbaugh, Dave A.;
Brutsche, Nancy E.;
Ibrahim, Lobna;
Zarate Jr, Carlos A.;
Mager, Donald E.;
Wainer, Irving W.

Publication type:

Article

The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine.

Published in:

British Journal of Clinical Pharmacology, 2002, v. 53, n. 5, p. 519, doi. 10.1046/j.1365-2125.2002.01578.x

By:

Yasuda, Sally Usdin;
Zannikos, Peter;
Young, Andrea E;
Fried, Karen M;
Wainer, Irving W;
Woosley, Raymond L

Publication type:

Article

A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer.

Published in:

British Journal of Clinical Pharmacology, 2000, v. 49, n. 5, p. 485, doi. 10.1046/j.1365-2125.2000.00189.x

By:

Williams, Marion L.;
Bhargava, Pankaj;
Cherrouk, Ilham;
Marshall, John L.;
Flockhart, David A.;
Wainer, Irving W.

Publication type:

Article

Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil.

Published in:

British Journal of Clinical Pharmacology, 1999, v. 47, n. 5, p. 545, doi. 10.1046/j.1365-2125.1999.00923.x

By:

Tracy, Timothy S.;
Korzekwa, Kenneth R.;
Gonzalez, Frank J.;
Wainer, Irving W.

Publication type:

Article

Verapamil metabolites: potential P-glycoprotein-medicated multidrug resistance reversal agents.

Published in:

Canadian Journal of Physiology & Pharmacology, 2003, v. 81, n. 8, p. 800, doi. 10.1139/y03-073

By:

Woodland, Cindy;
Koren, Gideon;
Wainer, Irving W.;
Batist, Gerry;
Ito, Shinya

Publication type:

Article

Stereochemistry: definitions and a note on nomenclature.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2001, v. 16, p. S105, doi. 10.1002/hup.334

By:

Caldwell, John;
Wainer, Irving W.

Publication type:

Article

Ketamine Metabolites Enantioselectively Decrease Intracellular D-Serine Concentrations in PC-12 Cells.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0149499

By:

Singh, Nagendra S.;
Rutkowska, Ewelina;
Plazinska, Anita;
Khadeer, Mohammed;
Moaddel, Ruin;
Jozwiak, Krzysztof;
Bernier, Michel;
Wainer, Irving W.

Publication type:

Article

N-acetylation among HIV-positive patients and patients with AIDS: When is fast, fast and slow, slow?*.

Published in:

Clinical Pharmacology & Therapeutics, 1997, v. 62, n. 3, p. 261, doi. 10.1016/S0009-9236(97)90028-X

By:

O'Neil, William M.;
Gilfix, Brian M.;
DiGirolamo, Antonietta;
Tsoukas, Christos M.;
Wainer, Irving W.

Publication type:

Article

Verapamil stereoisomers during racemic verapamil administration: Effects of aging and comparisons to administration of individual stereoisomers.

Published in:

Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 4, p. 368, doi. 10.1038/clpt.1994.151

By:

Schwartz, Janice B;
Capili, Helen;
Wainer, Irving W

Publication type:

Article

Verapamil decreases lymphocyte protein kinase C activity in humans.

Published in:

Clinical Pharmacology & Therapeutics, 1994, v. 55, n. 1, p. 44, doi. 10.1038/clpt.1994.8

By:

Depetrillo, Paolo B;
Abernethy, Darrell R;
Wainer, Irving W;
Andrawis, Nabil S

Publication type:

Article

Labetalol pharmacokinetics and pharmacodynamics: Evidence of stereoselective disposition.

Published in:

Clinical Pharmacology & Therapeutics, 1990, v. 48, n. 5, p. 509, doi. 10.1038/clpt.1990.187

By:

Lalonde, Richard L;
O'Rear, Tracey L;
Wainer, Irving W;
Drda, Kristin D;
Herring, Vanessa L;
Bottorff, Michael B

Publication type:

Article

Stereoselective and regiospecific hydroxylation of ketamine and norketamine.

Published in:

Xenobiotica, 2012, v. 42, n. 11, p. 1076, doi. 10.3109/00498254.2012.685777

By:

Desta, Zeruesenay;
Moaddel, Ruin;
Ogburn, Evan T.;
Xu, Cong;
Ramamoorthy, Anuradha;
Venkata, Swarajya Lakshmi Vattem;
Sanghvi, Mitesh;
Goldberg, Michael E.;
Torjman, Marc C.;
Wainer, Irving W.

Publication type:

Article

Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells.

Published in:

Xenobiotica, 2012, v. 42, n. 8, p. 748, doi. 10.3109/00498254.2012.662726

By:

Bhatia, Prateek;
Bernier, Michel;
Sanghvi, Mitesh;
Moaddel, Ruin;
Schwarting, Roland;
Ramamoorthy, Anuradha;
Wainer, Irving W.

Publication type:

Article

Drug Interaction: Meperidine and Chlorpromazine, a Toxic Combination.

Published in:

1981

By:

STAMBAUGH, JOHN E.;
WAINER, IRVING W.

Publication type:

Other

The Effect of Phenobarbital on the Metabolism of Meperidine in Normal Volunteers.

Published in:

1978

By:

STAMBAUGH, JOHN E.;
WAINER, IRVING W.;
SCHWARTZ, IRA

Publication type:

Other

The Clinical Pharmacology of Meperidine-Comparison of Routes of Administration.

Published in:

1976

By:

STAMBAUGH, JOHN E.;
WAINER, IRVING W.;
SANSTEAD, JOHN K.;
HEMPHILL, DOROTHEA M.

Publication type:

Other

The Bioavailability of Meperidine Using Urine Assays for Meperidine and Normeperidine.

Published in:

1975

By:

STAMBAUGH, JOHN E.;
WAINER, IRVING W.

Publication type:

Other

Drug Interactions I: Meperidine and Combination Oral Contraceptives.

Published in:

1975

By:

STAMBAUGH, JOHN E.;
WAINER, IRVING W.

Publication type:

Other

The Bioavailability of Meperidine.

Published in:

1974

By:

STAMBAUGH, JOHN E.;
WAINER, IRVING W.

Publication type:

Other

Enantioselective separation and online affinity chromatographic characterization of R,R- and S,S-fenoterol.

Published in:

Chirality, 2006, v. 18, n. 10, p. 822, doi. 10.1002/chir.20317

By:

Beigi, Farideh;
Bertucci, Carlo;
Zhu, Weizhong;
Chakir, Khalid;
Wainer, Irving W.;
Xiao, Rui-Ping;
Abernethy, Darrell R.

Publication type:

Article

Determination of the plasma levels of metyrapone and its enantiomeric metyrapol metabolites by direct plasma injection and multidimensional achiral-chiral chromatography.

Published in:

Chirality, 2002, v. 14, n. 9, p. 731, doi. 10.1002/chir.10133

By:

Cassiano, Neila M.;
Cass, Quezia B.;
Degani, Ana Luiza G.;
Wainer, Irving W.

Publication type:

Article

Erratum: Editor's note: Professor Andre Collet 1945-1999.

Published in:

Chirality, 2000, v. 12, n. 7, p. 598, doi. 10.1002/1520-636X(2000)12:7<598::AID-CHIR8>3.0.CO;2-9

By:

Caldwell, John;
Berova, Nina;
Armstrong, Daniel W.;
Davankov, Vadim;
Fell, Anthony F.;
Hacksell, Uli;
Koenig, Wilfried;
Lindner, Wolfgang;
Okamoto, Yoshio;
Pirkle, William H.;
Schurig, Volker;
Testa, Bernard;
Wainer, Irving W.;
Welch, Christopher J.;
Misiti, Dominico

Publication type:

Article

Professor André Collet 1945-1999.

Published in:

Chirality, 2000, v. 12, n. 1, p. 1, doi. 10.1002/(SICI)1520-636X(2000)12:1<1::AID-CHIR1>3.0.CO;2-1

By:

Caldwell, John;
Berova, Nina;
Armstrong, Daniel W.;
Davankov, Vadim;
Fell, Anthony F.;
Hacksell, Uli;
Koenig, Wilfried;
Lindner, Wolfgang;
Okamoto, Yoshio;
Pirkle, William H.;
Schurig, Volker;
Testa, Bernard;
Wainer, Irving W.;
Welch, Christopher J.

Publication type:

Article

Enantioselective induction of cyclophosphamide metabolism by phenytoin.

Published in:

Chirality, 1999, v. 11, n. 7, p. 569, doi. 10.1002/(SICI)1520-636X(1999)11:7<569::AID-CHIR9>3.0.CO;2-R

By:

Williams, Marion L.;
Wainer, Irving W.;
Embree, Leanne;
Barnett, Michael;
Granvil, Camille L.;
Ducharme, Murray P.

Publication type:

Article

Pharmacokinetics of (R)- and (S)-cyclophosphamide and their dechloroethylated metabolites in cancer patients.

Published in:

Chirality, 1999, v. 11, n. 4, p. 301, doi. 10.1002/(SICI)1520-636X(1999)11:4<301::AID-CHIR7>3.0.CO;2-R

By:

Williams, Marion L.;
Wainer, Irving W.;
Granvil, Camille P.;
Gehrcke, Barbel;
Bernstein, Mark L.;
Ducharme, Murray P.

Publication type:

Article