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Selective Targeting of Protein Kinase C (PKC)-θ Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8 + T Cells in Immunotherapy-Resistant and Metastatic Cancers.
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- Cancers, 2022, v. 14, n. 6, p. 1596, doi. 10.3390/cancers14061596
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- Article
PKA-site phosphorylation of importin13 regulates its subcellular localization and nuclear transport function.
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- Biochemical Journal, 2018, v. 475, n. 16, p. 2699, doi. 10.1042/BCJ20180082
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- Article
Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization.
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- Biochemical Journal, 2014, v. 461, n. 3, p. 469, doi. 10.1042/BJ20130709
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- Article
Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus.
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- Biochemical Journal, 2012, v. 443, n. 3, p. 851, doi. 10.1042/BJ20120150
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- Article
Histone-mediated Transduction as an Efficient Means for Gene Delivery.
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- Molecular Therapy, 2007, v. 15, n. 4, p. 721, doi. 10.1038/sj.mt.6300093
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- Article
Nuclear localization of the dystrophin-associated protein α-dystrobrevin through importin α2/β1 is critical for interaction with the nuclear lamina/maintenance of nuclear integrity.
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- FASEB Journal, 2015, v. 29, n. 5, p. 1842, doi. 10.1096/fj.14-257147
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- Article
Global enhancement of nuclear localization-dependent nuclear transport in transformed cells.
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- FASEB Journal, 2012, v. 26, n. 3, p. 1181, doi. 10.1096/fj.11-191585
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- Article
Efficient gene delivery using reconstituted chromatin enhanced for nuclear targeting.
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- FASEB Journal, 2008, v. 22, n. 7, p. 2232, doi. 10.1096/fj.07-099911
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- Article
Author Correction: Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31644-7
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- Article
The Nuclear Transporter Importin 13 Can Regulate Stress-Induced Cell Death through the Clusterin/KU70 Axis.
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- Cells (2073-4409), 2023, v. 12, n. 2, p. 279, doi. 10.3390/cells12020279
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- Article
High Throughput Screening Targeting the Dengue NS3-NS5 Interface Identifies Antivirals against Dengue, Zika and West Nile Viruses.
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- Cells (2073-4409), 2022, v. 11, n. 4, p. 730, doi. 10.3390/cells11040730
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- Article
Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal?
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- Cells (2073-4409), 2020, v. 9, n. 9, p. 2100, doi. 10.3390/cells9092100
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- Article
Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer.
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- Cells (2073-4409), 2019, v. 8, n. 3, p. 281, doi. 10.3390/cells8030281
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- Article
A Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection.
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- Journal of Infectious Diseases, 2014, v. 210, n. 11, p. 1780, doi. 10.1093/infdis/jiu319
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- Article
The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-ĸB p65.
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- PLoS Pathogens, 2010, v. 6, n. 5, p. 1, doi. 10.1371/journal.ppat.1000898
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- Article
Novel RU486 (mifepristone) analogues with increased activity against Venezuelan Equine Encephalitis Virus but reduced progesterone receptor antagonistic activity.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38671-y
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- Article
Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import.
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- Cellular Microbiology, 2019, v. 21, n. 1, p. N.PAG, doi. 10.1111/cmi.12953
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- Article
Nucleocytoplasmic shuttling of the West Nile virus RNA‐dependent RNA polymerase NS5 is critical to infection.
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- Cellular Microbiology, 2018, v. 20, n. 8, p. 1, doi. 10.1111/cmi.12848
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- Article
Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20194-0
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- Article
Importins and Beyond: Non-Conventional Nuclear Transport Mechanisms.
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- Traffic, 2009, v. 10, n. 9, p. 1188, doi. 10.1111/j.1600-0854.2009.00937.x
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- Article
Nuclear Import of β-Dystroglycan Is Facilitated by Ezrin-Mediated Cytoskeleton Reorganization.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090629
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- Article
Enhanced tumour cell nuclear targeting in a tumour progression model.
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- BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1045-z
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- Article
Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells.
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- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 11, p. 1, doi. 10.1371/journal.pntd.0005122
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- Article
The C-terminus of apoptin represents a unique tumor cell-enhanced nuclear targeting module.
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- International Journal of Cancer, 2008, v. 123, n. 12, p. 2965, doi. 10.1002/ijc.23884
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- Article
Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3310, doi. 10.3390/ijms22073310
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Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.
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- Scientific Reports, 2015, p. 9459, doi. 10.1038/srep09459
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Internalized Functional DNA Aptamers as Alternative Cancer Therapies.
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- Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.01115
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- Article
Increased In Vivo Exposure of N-(4-Hydroxyphenyl) Retinamide (4-HPR) to Achieve Plasma Concentrations Effective against Dengue Virus.
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- Pharmaceutics, 2023, v. 15, n. 7, p. 1974, doi. 10.3390/pharmaceutics15071974
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- Article
Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.
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- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150477
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Conservation of Importin α Function in Apicomplexans: Ivermectin and GW5074 Target Plasmodium falciparum Importin α and Inhibit Parasite Growth in Culture.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13899, doi. 10.3390/ijms232213899
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- Article