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γ-Secretase modulators reduce endogenous amyloid β<sub>42</sub> levels in human neural progenitor cells without altering neuronal differentiation.
- Published in:
- FASEB Journal, 2015, v. 29, n. 8, p. 3335, doi. 10.1096/fj.15-271015
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- Publication type:
- Article
STIM 1, an essential and conserved component of store-operated Ca<sub>2+</sub> channel function.
- Published in:
- Journal of Cell Biology, 2005, v. 169, n. 3, p. 435, doi. 10.1083/jcb.200502019
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- Publication type:
- Article
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate α-secretase activity.
- Published in:
- Human Molecular Genetics, 2009, v. 18, n. 20, p. 3987, doi. 10.1093/hmg/ddp323
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- Publication type:
- Article
Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase.
- Published in:
- Human Molecular Genetics, 2004, v. 13, n. 2, p. 159, doi. 10.1093/hmg/ddh019
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- Publication type:
- Article
Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin.
- Published in:
- Human Molecular Genetics, 2003, v. 12, n. 21, p. 2765, doi. 10.1093/hmg/ddg310
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- Publication type:
- Article
Inhibitors of Urokinase and Thrombin in Cultured Neural Cells.
- Published in:
- Journal of Neurochemistry, 1991, v. 56, n. 1, p. 234, doi. 10.1111/j.1471-4159.1991.tb02586.x
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- Publication type:
- Article
P1‐204: A NOVEL PHARMACOLOGICAL INTERVENTION TO NEUROINFLAMMATORY OUTCOMES OF AIR POLLUTION: THE GAMMA SECRETASE MODULATOR BPN‐15606 ATTENUATED MICROGLIAL AND AMYLOID INDUCTION BY URBAN NANO‐PARTICULATE (NPM) IN YOUNG MALE C57BL/6J MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P315, doi. 10.1016/j.jalz.2019.06.759
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- Publication type:
- Article
A three-dimensional human neural cell culture model of Alzheimer's disease.
- Published in:
- Nature, 2014, v. 515, n. 7526, p. 274, doi. 10.1038/nature13800
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- Publication type:
- Article
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.
- Published in:
- 2009
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- Publication type:
- journal article
Localization of protease nexin-1 on the fibroblast extracellular matrix.
- Published in:
- Journal of Cellular Physiology, 1988, v. 134, n. 2, p. 179, doi. 10.1002/jcp.1041340203
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- Publication type:
- Article
Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer's disease.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15120-3
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- Publication type:
- Article
Transcriptomic profiling of sporadic Alzheimer's disease patients.
- Published in:
- Molecular Brain, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13041-022-00963-2
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- Publication type:
- Article
Potential Role of Protease Nexin-2/Amyloid β-Protein Precursor as a Cerebral Anticoagulant<sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1992, v. 674, n. 1, p. 243, doi. 10.1111/j.1749-6632.1992.tb27493.x
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- Publication type:
- Article
Decreased levels of soluble amyloid β-protein precursor are associated with Alzheimer's disease in concordant and discordant monozygous twin pairs.
- Published in:
- Annals of Neurology, 1994, v. 36, n. 2, p. 215, doi. 10.1002/ana.410360214
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- Publication type:
- Article
Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis-dutch type share a decrease in cerebrospinal fluid levels of amyloid β-protein precursor.
- Published in:
- Annals of Neurology, 1992, v. 32, n. 2, p. 215, doi. 10.1002/ana.410320214
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- Publication type:
- Article
Effect of Potent γ-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1-Induced Pluripotent Stem Cell Mutant Carriers.
- Published in:
- JAMA Neurology, 2014, v. 71, n. 12, p. 1481, doi. 10.1001/jamaneurol.2014.2482
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- Publication type:
- Article
Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.
- Published in:
- Nature Neuroscience, 1999, v. 2, n. 8, p. 695, doi. 10.1038/11154
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- Publication type:
- Article
Altered Metabolism of Familial Alzheimer's Disease-Linked Amyloid Precursor Protein Variants in Yeast Artificial Chromosome Transgenic Mice.
- Published in:
- Human Molecular Genetics, 1997, v. 6, n. 9, p. 1535, doi. 10.1093/hmg/6.9.1535
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- Publication type:
- Article
A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP.
- Published in:
- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118379
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- Publication type:
- Article
Mechanism of gamma‐secretase modulators.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.064014
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- Publication type:
- Article
Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 2117, doi. 10.1002/alz.12553
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- Publication type:
- Article