Found: 49
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Local continual reassessment methods for dose finding and optimization in drug-combination trials.
- Published in:
- Statistical Methods in Medical Research, 2023, v. 32, n. 10, p. 2049, doi. 10.1177/09622802231192955
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- Publication type:
- Article
A web tool for designing and conducting phase I trials using the continual reassessment method.
- Published in:
- 2018
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- Publication type:
- journal article
Reducing Accidental Dislodgement of the Percutaneous Endoscopic Gastrostomy: A Prospective Trial of the "SafetyBreak" Device.
- Published in:
- 2016
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- Publication type:
- journal article
Continual Reassessment Method for Partial Ordering.
- Published in:
- Biometrics, 2011, v. 67, n. 4, p. 1555, doi. 10.1111/j.1541-0420.2011.01560.x
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- Publication type:
- Article
Bayesian Design for Identifying Cohort-Specific Optimal Dose Combinations Based on Multiple Endpoints: Application to a Phase I Trial in Non-Small Cell Lung Cancer.
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- International Journal of Environmental Research & Public Health, 2021, v. 18, n. 21, p. 11452, doi. 10.3390/ijerph182111452
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- Publication type:
- Article
Tailoring early-phase clinical trial design to address multiple research objectives.
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- Cancer Immunology, Immunotherapy, 2020, v. 69, n. 1, p. 95, doi. 10.1007/s00262-019-02442-5
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- Publication type:
- Article
Heterogeneity of CD8 tumor-infiltrating lymphocytes in non-small-cell lung cancer: impact on patient prognostic assessments and comparison of quantification by different sampling strategies.
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- Cancer Immunology, Immunotherapy, 2017, v. 66, n. 1, p. 33, doi. 10.1007/s00262-016-1908-4
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- Publication type:
- Article
Topical treatment of melanoma metastases with imiquimod, plus administration of a cancer vaccine, promotes immune signatures in the metastases.
- Published in:
- Cancer Immunology, Immunotherapy, 2016, v. 65, n. 10, p. 1201, doi. 10.1007/s00262-016-1880-z
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- Publication type:
- Article
Intratumoral interferon-gamma increases chemokine production but fails to increase T cell infiltration of human melanoma metastases.
- Published in:
- Cancer Immunology, Immunotherapy, 2016, v. 65, n. 10, p. 1189, doi. 10.1007/s00262-016-1881-y
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- Publication type:
- Article
Defining the effects of age and gender on immune response and outcomes to melanoma vaccination: a retrospective analysis of a single-institution clinical trials' experience.
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- Cancer Immunology, Immunotherapy, 2015, v. 64, n. 12, p. 1531, doi. 10.1007/s00262-015-1758-5
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- Publication type:
- Article
MYBL2-Driven Transcriptional Programs Link Replication Stress and Error-prone DNA Repair With Genomic Instability in Lung Adenocarcinoma.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.585551
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- Publication type:
- Article
IMMU-69. PROGNOSTIC IMPLICATION OF B-CELL INFILTRATE IN PATIENTS WITH GLIOBLASTOMA (GBM).
- Published in:
- Neuro-Oncology, 2018, v. 20, p. vi137, doi. 10.1093/neuonc/noy148.572
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- Publication type:
- Article
Coherence principles in interval‐based dose finding.
- Published in:
- Pharmaceutical Statistics, 2020, v. 19, n. 2, p. 137, doi. 10.1002/pst.1974
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- Publication type:
- Article
A Phase I/II adaptive design for heterogeneous groups with application to a stereotactic body radiation therapy trial.
- Published in:
- Pharmaceutical Statistics, 2015, v. 14, n. 4, p. 302, doi. 10.1002/pst.1686
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- Publication type:
- Article
Specifications of a continual reassessment method design for phase I trials of combined drugs Specifications of a continual reassessment method design for phase I trials of combined drugs.
- Published in:
- Pharmaceutical Statistics, 2013, v. 12, n. 4, p. 217, doi. 10.1002/pst.1575
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- Publication type:
- Article
Application of the patient-reported outcomes continual reassessment method to a phase I study of radiotherapy in endometrial cancer.
- Published in:
- International Journal of Biostatistics, 2023, v. 19, n. 1, p. 163, doi. 10.1515/ijb-2022-0023
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- Publication type:
- Article
SEMIPARAMETRIC DOSE FINDING METHODS FOR PARTIALLY ORDERED DRUG COMBINATIONS.
- Published in:
- Statistica Sinica, 2022, v. 32, n. 4, p. 1983, doi. 10.5705/ss.202020.0248
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- Publication type:
- Article
Using the time-to-event continual reassessment method in the presence of partial orders.
- Published in:
- Statistics in Medicine, 2013, v. 32, n. 1, p. 131, doi. 10.1002/sim.5491
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- Publication type:
- Article
Proliferating CD8 + T Cell Infiltrates Are Associated with Improved Survival in Glioblastoma.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 12, p. 3378, doi. 10.3390/cells10123378
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- Publication type:
- Article
Preface to the themed issue on 'Early phase clinical trial design methodology'.
- Published in:
- Journal of the Royal Statistical Society: Series C (Applied Statistics), 2019, v. 68, n. 2, p. 267, doi. 10.1111/rssc.12329
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- Publication type:
- Article
Change in parathyroid hormone levels from baseline predicts hypocalcemia following total or completion thyroidectomy.
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- Head & Neck, 2022, v. 44, n. 7, p. 1588, doi. 10.1002/hed.27057
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- Publication type:
- Article
Correction to: Incidence, risk factors and management of venous thromboembolism in patients with primary CNS lymphoma.
- Published in:
- 2021
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- Publication type:
- Correction Notice
Incidence, risk factors and management of venous thromboembolism in patients with primary CNS lymphoma.
- Published in:
- Journal of Neuro-Oncology, 2021, v. 154, n. 1, p. 41, doi. 10.1007/s11060-021-03791-x
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- Publication type:
- Article
Relationship of dose to vascular target volumes and local failure in pancreatic cancer patients undergoing neoadjuvant chemoradiation.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.906484
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- Publication type:
- Article
Informed Consent for Research on Medical Practices.
- Published in:
- 2015
- By:
- Publication type:
- commentary
Implementation of adaptive methods in early-phase clinical trials.
- Published in:
- 2017
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- Publication type:
- journal article
Identifying a maximum tolerated contour in two-dimensional dose finding.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Performance of toxicity probability interval based designs in contrast to the continual reassessment method.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Designs for phase I trials in ordered groups.
- Published in:
- 2017
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- Publication type:
- journal article
Dimension of model parameter space and operating characteristics in adaptive dose-finding studies.
- Published in:
- 2016
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- Publication type:
- journal article
A comparative study of adaptive dose-finding designs for phase I oncology trials of combination therapies.
- Published in:
- 2015
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- Publication type:
- journal article
Comments on 'Competing designs for drug combination in phase I dose-finding clinical trials' by M-K. Riviere, F. Dubois, S. Zohar.
- Published in:
- Statistics in Medicine, 2015, v. 34, n. 1, p. 18, doi. 10.1002/sim.6336
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- Publication type:
- Article
Phase I/II adaptive design for drug combination oncology trials.
- Published in:
- Statistics in Medicine, 2014, v. 33, n. 12, p. 1990, doi. 10.1002/sim.6097
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- Publication type:
- Article
Comments on 'A dose-finding approach based on shrunken predictive probability for combinations of two agents in phase I trials' by Akihiro Hirakawa, Chikuma Hamada, and Shigeyuki Matsui.
- Published in:
- Statistics in Medicine, 2014, v. 33, n. 12, p. 2156, doi. 10.1002/sim.5934
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- Publication type:
- Article
Phase I design for completely or partially ordered treatment schedules.
- Published in:
- Statistics in Medicine, 2014, v. 33, n. 4, p. 569, doi. 10.1002/sim.5998
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- Publication type:
- Article
Venetoclax with decitabine or azacitidine in the first‐line treatment of acute myeloid leukemia.
- Published in:
- EJHaem, 2023, v. 4, n. 2, p. 381, doi. 10.1002/jha2.663
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- Publication type:
- Article
Seamless Designs: Current Practice and Considerations for Early-Phase Drug Development in Oncology.
- Published in:
- 2019
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- Publication type:
- journal article
Venetoclax with decitabine or azacitidine in relapsed or refractory acute myeloid leukemia.
- Published in:
- Medical Oncology, 2024, v. 41, n. 3, p. 1, doi. 10.1007/s12032-024-02302-y
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- Publication type:
- Article
A Pilot Study of the Combination of Entinostat with Capecitabine in Advanced Breast Cancer.
- Published in:
- International Journal of Breast Cancer, 2024, v. 2024, p. 1, doi. 10.1155/2024/5515966
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- Publication type:
- Article
Applications of the partial-order continual reassessment method in the early development of treatment combinations.
- Published in:
- Clinical Trials, 2024, v. 21, n. 3, p. 331, doi. 10.1177/17407745241234634
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- Publication type:
- Article
Current issues in dose-finding designs: A response to the US Food and Drug Adminstration's Oncology Center of Excellence Project Optimus.
- Published in:
- Clinical Trials, 2024, v. 21, n. 3, p. 267, doi. 10.1177/17407745241234652
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- Publication type:
- Article
Adapting isotonic dose-finding to a dynamic set of drug combinations with application to a phase I leukemia trial.
- Published in:
- Clinical Trials, 2021, v. 18, n. 3, p. 314, doi. 10.1177/1740774520983484
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- Publication type:
- Article
Adaptive dose-finding based on safety and feasibility in early-phase clinical trials of adoptive cell immunotherapy.
- Published in:
- Clinical Trials, 2020, v. 17, n. 2, p. 157, doi. 10.1177/1740774519890145
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- Publication type:
- Article
Evaluation of irrational dose assignment definitions using the continual reassessment method.
- Published in:
- Clinical Trials, 2019, v. 16, n. 6, p. 665, doi. 10.1177/1740774519873316
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- Publication type:
- Article
Revisiting isotonic phase I design in the era of model-assisted dose-finding.
- Published in:
- Clinical Trials, 2018, v. 15, n. 5, p. 524, doi. 10.1177/1740774518792258
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- Publication type:
- Article
Shift models for dose-finding in partially ordered groups.
- Published in:
- Clinical Trials, 2019, v. 16, n. 1, p. 32, doi. 10.1177/1740774518801599
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- Publication type:
- Article
A web application for evaluating Phase I methods using a non-parametric optimal benchmark.
- Published in:
- Clinical Trials, 2017, v. 14, n. 5, p. 553, doi. 10.1177/1740774517715456
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- Publication type:
- Article
Performance of two-stage continual reassessment method relative to an optimal benchmark.
- Published in:
- Clinical Trials, 2013, v. 10, n. 6, p. 862, doi. 10.1177/1740774513503521
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- Publication type:
- Article
Dose-finding design for multi-drug combinations.
- Published in:
- Clinical Trials, 2011, v. 8, n. 4, p. 380, doi. 10.1177/1740774511408748
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- Publication type:
- Article