Works by Wadelius, Claes

Results: 52

Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases.

Published in:

Human Genomics, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s40246-019-0204-8

By:

Cavalli, Marco;
Baltzer, Nicholas;
Pan, Gang;
Bárcenas Walls, José Ramón;
Smolinska Garbulowska, Karolina;
Kumar, Chanchal;
Skrtic, Stanko;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

lobChIP: from cells to sequencing ready ChIP libraries in a single day.

Published in:

Epigenetics & Chromatin, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13072-015-0017-5

By:

Wallerman, Ola;
Nord, Helena;
Bysani, Madhusudhan;
Borghini, Lisa;
Wadelius, Claes

Publication type:

Article

Venous thrombosis: factor V G1691A genotyping related to APC resistance as measured by 2 methods.

Published in:

European Journal of Haematology, 1997, v. 58, n. 4, p. 229, doi. 10.1111/j.1600-0609.1997.tb01659.x

By:

Alderborn, Anders;
Siegbahn, Agneta;
Wadelius, Claes

Publication type:

Article

Functional annotation of noncoding mutations in cancer.

Published in:

Life Science Alliance, 2021, v. 4, n. 9, p. 1, doi. 10.26508/lsa.201900523

By:

Umer, Husen M.;
Smolinska, Karolina;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Multifaceted regulation of hepatic lipid metabolism by YY1.

Published in:

Life Science Alliance, 2021, v. 4, n. 7, p. 1, doi. 10.26508/lsa.202000928

By:

Gang Pan;
Diamanti, Klev;
Cavalli, Marco;
Gutiérrez, Ariadna Lara;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Evidence for a second gene for primary microcephaly at MCPH5 on chromosome 1.

Published in:

Hereditas, 2003, v. 139, n. 1, p. 64, doi. 10.1111/j.1601-5223.2003.01682.x

By:

Wallerman, Ola;
Van Eeghen, Agnies;
Ten Kate, Leo P.;
Wadelius, Claes

Publication type:

Article

Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 22, p. 7498, doi. 10.1093/nar/gkp823

By:

Wallerman, Ola;
Motallebipour, Mehdi;
Enroth, Stefan;
Patra, Kalicharan;
Bysani, Madhu Sudhan Reddy;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 12, p. e85, doi. 10.1093/nar/gkp381

By:

Ameur, Adam;
Rada-Iglesias, Alvaro;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Best vitelliform macular dystrophy in a Swedish family: genetic analysis and a seven-year follow-up of photodynamic treatment of a young boy with choroidal neovascularization.

Published in:

Acta Ophthalmologica (1755375X), 2014, v. 92, n. 3, p. 238, doi. 10.1111/aos.12142

By:

Frennesson, Christina I.;
Wadelius, Claes;
Nilsson, Sven Erik G.

Publication type:

Article

Identification of the gene responsible for Best macular dystrophy.

Published in:

Nature Genetics, 1998, v. 19, n. 3, p. 241, doi. 10.1038/915

By:

Petrukhin, Konstantin;
Koisti, Markus J.;
Bakall, Benjamin;
Li, Wen;
Xie, Guochun;
Marknell, Towa;
Sandgren, Ola;
Forsman, Kristina;
Holmgren, Gösta;
Andreasson, Sten;
Vujic, Mihailo;
Bergen, Arthur A. B.;
McGarty-Dugan, Valarie;
Figueroa, David;
Austin, Christopher P.;
Metzker, Michael L.;
Caskey, C.Thomas;
Wadelius, Claes

Publication type:

Article

A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells.

Published in:

Lipids in Health & Disease, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12944-024-02029-9

By:

Castillejo-López, Casimiro;
Bárcenas-Walls, José Ramón;
Cavalli, Marco;
Larsson, Anders;
Wadelius, Claes

Publication type:

Article

A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells.

Published in:

Lipids in Health & Disease, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12944-024-02029-9

By:

Castillejo-López, Casimiro;
Bárcenas-Walls, José Ramón;
Cavalli, Marco;
Larsson, Anders;
Wadelius, Claes

Publication type:

Article

Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection.

Published in:

FEBS Journal, 2009, v. 276, n. 7, p. 1878, doi. 10.1111/j.1742-4658.2009.06914.x

By:

Motallebipour, Mehdi;
Enroth, Stefan;
Punga, Tanel;
Ameur, Adam;
Koch, Christoph;
Dunham, Ian;
Komorowski, Jan;
Ericsson, Johan;
Wadelius, Claes

Publication type:

Article

Monte Carlo feature selection for supervised classification.

Published in:

Bioinformatics, 2008, v. 24, n. 1, p. 110, doi. 10.1093/bioinformatics/btm486

By:

Michal Draminski;
Alvaro Rada-Iglesias;
Stefan Enroth;
Claes Wadelius;
Jacek Koronacki;
Jan Komorowski

Publication type:

Article

Analysis of Rare Variants and Common Haplotypes in the Optineurin Gene in Swedish Glaucoma Cases.

Published in:

Ophthalmic Genetics, 2005, v. 26, n. 2, p. 85, doi. 10.1080/13816810490967953

By:

Jansson, Mattias;
Wadelius, Claes;
Rezaie, Tayebeh;
Sarfarazi, Mansoor

Publication type:

Article

Allelic variants in the MYOC/TIGR gene in patients with primary open-angle. exfoliative glaucoma and unaffected controls.

Published in:

Ophthalmic Genetics, 2003, v. 24, n. 2, p. 103, doi. 10.1076/opge.24.2.103.13997

By:

Jansson, Mattias;
Marknell, Towa;
Tomic, Lidija;
Larsson, Lill-Inger;
Wadelius, Claes

Publication type:

Article

Best's vitelliform macular dystrophy caused by a new mutation(Val89Ala) in the VMD2 gene.

Published in:

Ophthalmic Genetics, 2001, v. 22, n. 2, p. 107, doi. 10.1076/opge.22.2.107.2226

By:

Eksandh, Louise;
Bakall, Benjamin;
Bauer, Birgitta;
Wadelius, Claes;
Andréasson, Sten

Publication type:

Article

Clinical expression of Best's vitelliform macular dystrophy inSwedish families with mutations in the bestrophin gene.

Published in:

Ophthalmic Genetics, 1999, v. 20, n. 4, p. 251, doi. 10.1076/opge.20.4.251.2270

By:

Ponjavic, Vesna;
Eksandh, Louise;
Andréasson, Sten;
Sjöström, Kerstin;
Bakall, B.;
Ingvast, S.;
Wadelius, Claes;
Ehinger, Berndt

Publication type:

Article

Genetic mapping using fluorescent quantification of allele frequencies in pooled DNA loaded by solid support.

Published in:

Clinical Genetics, 1997, v. 51, n. 3, p. 145, doi. 10.1111/j.1399-0004.1997.tb02444.x

By:

Graff, Caroline;
Persson, Anja;
Ulfendahi, Per Johan;
Wahlberg, Johan;
Wadelius, Claes

Publication type:

Article

The gene for Best's macular dystrophy is located at 11q13 in a Swedish family.

Published in:

Clinical Genetics, 1992, v. 42, n. 3, p. 156, doi. 10.1111/j.1399-0004.1992.tb03229.x

By:

Forsman, Kristina;
Graff, Caroline;
Nordström, Stefan;
Johansson, Kent;
Westermark, Eleonora;
Lundgren, Erik;
Gustavson, Karl-Henrik;
Wadelius, Claes;
Holmgren, Gösta

Publication type:

Article

Linkage analysis in properdin deficiency families: refined location in proximal Xp.

Published in:

Clinical Genetics, 1992, v. 42, n. 1, p. 8, doi. 10.1111/j.1399-0004.1992.tb03126.x

By:

Wadelius, Claes;
Pigg, Maritta;
Sundvall, Mats;
Sjöholm, Anders G.;
Goonewardena, Ponmani;
Kuijper, Ed J.;
Tijssen, Cees C.;
Jansz, Anton;
Späth, Peter J.;
Schaad, Ulf B.;
Tranebjaerg, Lisbeth;
Nielsen, Hans E.;
Söderström, Claos;
Annerén, Göran;
Pettersson, Ulf

Publication type:

Article

Multiplex PCR excludes Duchenne muscular dystrophy in a twin pregnancy.

Published in:

Clinical Genetics, 1991, v. 39, n. 4, p. 314, doi. 10.1111/j.1399-0004.1991.tb03035.x

By:

Wadelius, Claes;
Annéren, Göran;
Dahl, Niklas;
Holmgren, Gösta;
Gustavson, Karl-Henrik

Publication type:

Article

Author Correction: Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.

Published in:

2019

By:

Diamanti, Klev;
Cavalli, Marco;
Pan, Gang;
Pereira, Maria J.;
Kumar, Chanchal;
Skrtic, Stanko;
Grabherr, Manfred;
Risérus, Ulf;
Eriksson, Jan W.;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Correction Notice

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45906-5

By:

Diamanti, Klev;
Cavalli, Marco;
Pan, Gang;
Pereira, Maria J.;
Kumar, Chanchal;
Skrtic, Stanko;
Grabherr, Manfred;
Risérus, Ulf;
Eriksson, Jan W.;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39633-0

By:

Cavalli, Marco;
Baltzer, Nicholas;
Umer, Husen M.;
Grau, Jan;
Lemnian, Ioana;
Pan, Gang;
Wallerman, Ola;
Spalinskas, Rapolas;
Sahlén, Pelin;
Grosse, Ivo;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

SICTIN: Rapid footprinting of massively parallel sequencing data.

Published in:

BioData Mining, 2010, v. 3, p. 4, doi. 10.1186/1756-0381-3-4

By:

Enroth, Stefan;
Andersson, Robin;
Wadelius, Claes;
Komorowski, Jan

Publication type:

Article

Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1485-5

By:

Bornelöv, Susanne;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 300, doi. 10.1186/s12864-015-1485-5

By:

Bornelöv, Susanne;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Spectrum of mutations and sequence variants in the FALDH gene in patients with Sjögren-Larsson syndrome.

Published in:

Human Mutation, 1998, v. 12, n. 6, p. 377, doi. 10.1002/(SICI)1098-1004(1998)12:6<377::AID-HUMU3>3.0.CO;2-I

By:

Sillén, Anna;
Anton-Lamprecht, Ingrun;
Braun-Quentin, Cordula;
Kraus, Cornelia S.;
Sayli, Bekir Sitki;
Ayuso, Carmen;
Jagell, Sten;
Küster, Wolfgang;
Wadelius, Claes

Publication type:

Article

A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements.

Published in:

Algorithms for Molecular Biology, 2012, v. 7, n. 1, p. 1, doi. 10.1186/1748-7188-7-2

By:

Enroth, Stefan;
Andersson, Claes R.;
Andersson, Robin;
Wadelius, Claes;
Gustafsson, Mats G.;
Komorowski, Jan

Publication type:

Article

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.

Published in:

Human Genetics, 2016, v. 135, n. 5, p. 485, doi. 10.1007/s00439-016-1654-x

By:

Cavalli, Marco;
Pan, Gang;
Nord, Helena;
Wallerman, Ola;
Wallén Arzt, Emelie;
Berggren, Olof;
Elvers, Ingegerd;
Eloranta, Maija-Leena;
Rönnblom, Lars;
Lindblad Toh, Kerstin;
Wadelius, Claes

Publication type:

Article

Association of warfarin dose with genes involved in its action and metabolism.

Published in:

Human Genetics, 2007, v. 121, n. 1, p. 23, doi. 10.1007/s00439-006-0260-8

By:

Wadelius, Mia;
Chen, Leslie;
Eriksson, Niclas;
Bumpstead, Suzannah;
Ghori, Jilur;
Wadelius, Claes;
Bentley, David;
McGinnis, Ralph;
Deloukas, Panos

Publication type:

Article

Linkage analysis identifies the thyroglobulin gene region as a major locus for familial congenital hypothyroidism.

Published in:

Human Genetics, 2002, v. 110, n. 2, p. 145, doi. 10.1007/s00439-002-0680-z

By:

Ahlbom, Bodil;
Yaqoob, Muhammad;
Gustavsson, Peter;
Abbas, Hafez;
Annerén, Göran;
Larsson, Agne;
Wadelius, Claes

Publication type:

Article

Single nucleus transcriptomics data integration recapitulates the major cell types in human liver.

Published in:

Hepatology Research, 2021, v. 51, n. 2, p. 233, doi. 10.1111/hepr.13585

By:

Diamanti, Klev;
Inda Díaz, Juan Salvador;
Raine, Amanda;
Pan, Gang;
Wadelius, Claes;
Cavalli, Marco

Publication type:

Article

Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK.

Published in:

Hepatology Research, 2017, v. 47, n. 8, p. 826, doi. 10.1111/hepr.12810

By:

Cavalli, Marco;
Pan, Gang;
Nord, Helena;
Wallén Arzt, Emelie;
Wallerman, Ola;
Wadelius, Claes

Publication type:

Article

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 5, p. 2408, doi. 10.1093/nar/gkw1186

By:

Gang Pan;
Ameur, Adam;
Enroth, Stefan;
Bysani, Madhusudhan;
Nord, Helena;
Cavalli, Marco;
Essand, Magnus;
Gyllensten, Ulf;
Wadelius, Claes

Publication type:

Article

Maps of context-dependent putative regulatory regions and genomic signal interactions.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 19, p. 9110, doi. 10.1093/nar/gkw800

By:

Diamanti, Klev;
Umer, Husen M.;
Kruczyk, Marcin;
Dąbrowski, Michał J.;
Cavalli, Marco;
Wadelius, Claes;
Komorowski, Jan

Publication type:

Article

Nucleosome regulatory dynamics in response to TGFβ.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 11, p. 6921, doi. 10.1093/nar/gku326

By:

Enroth, Stefan;
Andersson, Robin;
Bysani, Madhusudhan;
Wallerman, Ola;
Termén, Stefan;
Tuch, Brian B.;
De La Vega, Francisco M.;
Heldin, Carl-Henrik;
Moustakas, Aristidis;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article

Machine Learning-Based Analysis of Glioma Grades Reveals Co-Enrichment.

Published in:

Cancers, 2022, v. 14, n. 4, p. 1014, doi. 10.3390/cancers14041014

By:

Garbulowski, Mateusz;
Smolinska, Karolina;
Çabuk, Uğur;
Yones, Sara A.;
Celli, Ludovica;
Yaz, Esma Nur;
Barrenäs, Fredrik;
Diamanti, Klev;
Wadelius, Claes;
Komorowski, Jan

Publication type:

Article

Lowe's oculocerebrorenal syndrome - variation in lens changes in the carrier state.

Published in:

Acta Ophthalmologica (1755375X), 1991, v. 69, n. 1, p. 102, doi. 10.1111/j.1755-3768.1991.tb02002.x

By:

Fagerholm, Per;
Annerén, Göran;
Wadelius, Claes

Publication type:

Article

Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca<sup>2+</sup> channels in retinal pigment epithelial cells.

Published in:

FASEB Journal, 2006, v. 20, n. 1, p. 178, doi. 10.1096/fj.05-4495fje

By:

Rosenthal, Rita;
Bakall, Benjamin;
Kinnick, Tyson;
Peachey, Neal;
Wimmers, Sönke;
Wadelius, Claes;
Marmorstein, Alan;
Strauss, Olaf

Publication type:

Article

Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa.

Published in:

2011

By:

Enroth, Stefan;
Rada-Iglesisas, Alvaro;
Andersson, Robin;
Wallerman, Ola;
Wanders, Alkwin;
Påhlman, Lars;
Komorowski, Jan;
Wadelius, Claes

Publication type:

journal article

Mutation analysis for prenatal diagnosis and heterozygote detection of Gaucher disease type III (Norrbottnian type).

Published in:

1992

By:

Dahl, Niklas;
Wadelius, Claes;
Annerén, Göran;
Gustavson, Karl-Henrik;
Dahl, N;
Wadelius, C;
Annerén, G;
Gustavson, K H

Publication type:

journal article

Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64524-0

By:

Diamanti, Klev;
Visvanathar, Robin;
Pereira, Maria J.;
Cavalli, Marco;
Pan, Gang;
Kumar, Chanchal;
Skrtic, Stanko;
Risérus, Ulf;
Eriksson, Jan W.;
Kullberg, Joel;
Komorowski, Jan;
Wadelius, Claes;
Ahlström, Håkan

Publication type:

Article

Combinations of Histone Modifications Mark Exon Inclusion Levels.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029911

By:

Enroth, Stefan;
Bornelöv, Susanne;
Wadelius, Claes;
Komorowski, Jan

Publication type:

Article

Placental transfer of quetiapine in relation to P-glycoprotein activity.

Published in:

2007

By:

Rahi, Melissa;
Heikkinen, Tuija;
Härtter, Sebastian;
Hakkola, Jukka;
Hakala, Kristo;
Wallerman, Ola;
Wadelius, Mia;
Wadelius, Claes;
Laine, Kari;
Härtter, Sebastian

Publication type:

journal article

The heart of the matter--new insights into the genetics of cardiomyopathy.

Published in:

2000

By:

Wadelius, Claes;
Wadelius, C

Publication type:

journal article

Functional role of P-glycoprotein in the human blood-placental barrier

Published in:

Clinical Pharmacology & Therapeutics, 2005, v. 78, n. 2, p. 123, doi. 10.1016/j.clpt.2005.04.014

By:

Mölsä, Melissa;
Heikkinen, Tuija;
Hakkola, Jukka;
Hakala, Kristo;
Wallerman, Ola;
Wadelius, Mia;
Wadelius, Claes;
Laine, Kari

Publication type:

Article

scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09798-2

By:

Raine, Amanda;
Lundmark, Anders;
Annett, Alva;
Wiman, Ann-Christin;
Cavalli, Marco;
Wadelius, Claes;
Bergin, Claudia;
Nordlund, Jessica

Publication type:

Article

A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers.

Published in:

Human Mutation, 2016, v. 37, n. 9, p. 904, doi. 10.1002/humu.23014

By:

Umer, Husen M.;
Cavalli, Marco;
Dabrowski, Michal J.;
Diamanti, Klev;
Kruczyk, Marcin;
Pan, Gang;
Komorowski, Jan;
Wadelius, Claes

Publication type:

Article