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An in Vitro Model for Disease-specific Immunotherapy in Myasthenia Gravis Using Soluble MHC Class II Bound to AChR-derived Peptidea.
Published in:
Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 577, doi. 10.1111/j.1749-6632.1993.tb22946.x
By:
- NICOLLE, M. W.;
- VINCENT, A.;
- SHARMA, S.;
- NAG, B.;
- WILLCOX, N.;
- NEWSOM-DAVIS, J.
Publication type:
Article
Differential Recognition by T Cells of the P3A+ and P3A- Isoforms of the Human Acetylcholine Receptor Alpha-Subunit.
Published in:
Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 280, doi. 10.1111/j.1749-6632.1993.tb22894.x
By:
- BATOCCHI, A-P.;
- HARCOURT, G.;
- BEESON, D.;
- PANTIC, N.;
- HAWKE, S.;
- WILLCOX, N.;
- NEWSOM-DAVIS, J.
Publication type:
Article
Stimulation of Specific T Cells by Human A ChR Adsorbed to Immunomagnetic Particles.
Published in:
Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 288, doi. 10.1111/j.1749-6632.1993.tb22897.x
By:
- HAWKE, S.;
- WILLCOX, N.;
- HARCOURT, G.;
- VINCENT, A.;
- NEWSOM-DAVIS, J.
Publication type:
Article
Approaches for Studying the Pathogenic T Cells in Autoimmune Patientsa.
Published in:
Annals of the New York Academy of Sciences, 1993, v. 681, n. 1, p. 219, doi. 10.1111/j.1749-6632.1993.tb22888.x
By:
- WILLCOX, N.;
- BAGGI, F.;
- BATOCCHI, A-P.;
- BEESON, D.;
- HARCOURT, G.;
- HAWKE, S.;
- JACOBSON, L.;
- MATSUO, H.;
- MOODY, A-M.;
- NAGVEKAR, N.;
- NICOLLE, M.;
- ONG, B.;
- PANTIC, N.;
- NEWSOM-DAVIS, J.;
- VINCENT, A.
Publication type:
Article
Blood and Thymic Lymphocyte Responses to Peptide Sequences of the Acetylcholine Receptor in Myasthenia Gravis.
Published in:
Annals of the New York Academy of Sciences, 1988, v. 540, n. 1, p. 354, doi. 10.1111/j.1749-6632.1988.tb27097.x
By:
- HARCOURT, G.;
- SOMMER, N.;
- ROTHBARD, J.;
- BEESON, D.;
- WILLCOX, N.;
- NEWSOM-DAVIS, J.
Publication type:
Article
Thymus dependence of the antibody response to tetanus toxoid in mice.
Published in:
Clinical & Experimental Immunology, 1975, v. 22, n. 2, p. 341
By:
- Willcox, H. N. A.
Publication type:
Article
Spontaneous production of anti-IFN-α and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor.
Published in:
International Immunology, 2003, v. 15, n. 8, p. 903
By:
- N. Willcox;
- H. Shiono;
- Y.L. Wong;
- I. Matthews;
- J-L. Liu;
- W. Zhang;
- G. Sims;
- A. Meager;
- D. Beeson;
- A. Vincent
Publication type:
Article
Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1).
Published in:
Journal of Pathology, 2007, v. 211, n. 5, p. 563, doi. 10.1002/path.2141
By:
- Ströbel, P;
- Murumägi, A;
- Klein, R;
- Luster, M;
- Lahti, M;
- Krohn, K;
- Schalke, B;
- Nix, W;
- Gold, R;
- Rieckmann, P;
- Toyka, K;
- Burek, C;
- Rosenwald, A;
- Müller-Hermelink, HK;
- Pujoll-Borrell, R;
- Meager, A;
- Willcox, N;
- Peterson, P;
- Marx, A
Publication type:
Article
Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in Sardinian patients.
Published in:
2012
By:
- Meloni A;
- Willcox N;
- Meager A;
- Atzeni M;
- Wolff AS;
- Husebye ES;
- Furcas M;
- Rosatelli MC;
- Cao A;
- Congia M
Publication type:
Journal Article
Scenarios for Autoimmunization of T and B Cells in Myasthenia Gravis.
Published in:
Annals of the New York Academy of Sciences, 2003, v. 998, n. 1, p. 237, doi. 10.1196/annals.1254.026
By:
- SHIONO, H.;
- ROXANIS, I.;
- ZHANG, W.;
- SIMS, G. P.;
- MEAGER, A.;
- JACOBSON, L. W.;
- LIU, J-L.;
- MATTHEWS, I.;
- WONG, Y-L.;
- BONIFATI, M.;
- MICKLEM, K.;
- STOTT, D. I.;
- TODD, J. A.;
- BEESON, D.;
- VINCENT, A.;
- WILLCOX, N.
Publication type:
Article
Thymus, Thymoma, and Specific T Cells in Myasthenia Gravisa.
Published in:
Annals of the New York Academy of Sciences, 1998, v. 841, n. 1, p. 371, doi. 10.1111/j.1749-6632.1998.tb10950.x
By:
- BEESON, D.;
- BOND, A. P.;
- CORLETT, L.;
- CURNOW, S. J.;
- HILL, M. E.;
- JACOBSON, L. W.;
- MACLENNAN, C.;
- MEAGER, A.;
- MOODY, A-M.;
- MOSS, P.;
- NAGVEKAR, N.;
- NEWSOM-DAVIS, J.;
- PANTIC, N.;
- ROXANIS, I.;
- SPACK, E.G.;
- VINCENT, A.;
- WILLCOX, N.
Publication type:
Article
Muscle Nicotinic Acetylcholine Receptor mRNA Expression in Hyperplastic and Neoplastic Myasthenia Gravis Thymusa.
Published in:
Annals of the New York Academy of Sciences, 1998, v. 841, n. 1, p. 407, doi. 10.1111/j.1749-6632.1998.tb10954.x
By:
- MacLENNAN, C. A.;
- BEESON, D.;
- WILLCOX, N;
- VINCENT, A.;
- NEWSOM-DAVIS, J.
Publication type:
Article
Production of Fab Fragments against the Human Acetylcholine Receptor from Myasthenia Gravis Thymus Lambda and Kappa Phage Librariesa.
Published in:
Annals of the New York Academy of Sciences, 1998, v. 841, n. 1, p. 418, doi. 10.1111/j.1749-6632.1998.tb10957.x
By:
- MATTHEWS, I.;
- FARRAR, J.;
- McLACHLAN, S.;
- RAPOPORT, B.;
- NEWSOM-DAVIS, J.;
- WILLCOX, N.;
- VINCENT, A.
Publication type:
Article
Thymoma-An Expanded Cortical Epithelial Subset?
Published in:
Annals of the New York Academy of Sciences, 1987, v. 505, n. 1, p. 813, doi. 10.1111/j.1749-6632.1987.tb51378.x
By:
- SCHLUEP, M.;
- CHRISTENSSON, B.;
- WILLCOX, N.;
- NEWSOM-DAVIS, J.;
- JANOSSY, G.;
- RITTER, M.;
- SCHUURMAN, H.-J.;
- BIBERFELD, P.;
- MATELL, G.
Publication type:
Article
Development of an Adjuvant-Independent Model of Myasthenia Gravis in Mice.
Published in:
Annals of the New York Academy of Sciences, 1987, v. 505, n. 1, p. 806, doi. 10.1111/j.1749-6632.1987.tb51376.x
By:
- JERMY, A. C.;
- FISHER, C. A.;
- VINCENT, A.;
- WILLCOX, H. N. A.;
- NEWSOM-DAVIS, J.
Publication type:
Article
Genetic Susceptibility to Myasthenia Gravis Studied by DNA Hybridization.
Published in:
Annals of the New York Academy of Sciences, 1987, v. 505, n. 1, p. 800, doi. 10.1111/j.1749-6632.1987.tb51374.x
By:
- DEMAINE, A. G.;
- WELSH, K. I.;
- WILLCOX, N.;
- NEWSOM-DAVIS, J.
Publication type:
Article
Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis.
Published in:
Clinical & Experimental Immunology, 2003, v. 132, n. 1, p. 128, doi. 10.1046/j.1365-2249.2003.02113.x
By:
- MEAGER, A.;
- WADHWA, M.;
- DILGER, P.;
- BIRD, C.;
- THORPE, R.;
- NEWSOM-DAVIS, J.;
- WILLCOX, N.
Publication type:
Article
Cell types required for anti-acetylcholine receptor antibody synthesis by cultured thymocytes and blood lymphocytes in myasthenia gravis.
Published in:
Clinical & Experimental Immunology, 1984, v. 58, n. 1, p. 97
By:
- Willcox, H. N. A.;
- Newsom-Davis, J.;
- Calder, L. R.
Publication type:
Article
Greatly increased autoantibody production in myasthenia gravis by thymocyte suspensions prepared with proteolytic enzymes.
Published in:
Clinical & Experimental Immunology, 1983, v. 54, n. 2, p. 378
By:
- Willcox, H. N. A.;
- Newsom-Davis, J.;
- Calder, L. R.
Publication type:
Article
IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis.
Published in:
2008
By:
- Leite MI;
- Jacob S;
- Viegas S;
- Cossins J;
- Clover L;
- Morgan BP;
- Beeson D;
- Willcox N;
- Vincent A;
- Leite, Maria Isabel;
- Jacob, Saiju;
- Viegas, Stuart;
- Cossins, Judy;
- Clover, Linda;
- Morgan, B Paul;
- Beeson, David;
- Willcox, Nick;
- Vincent, Angela
Publication type:
journal article
Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.
Published in:
Clinical & Experimental Immunology, 2013, v. 171, n. 3, p. 263, doi. 10.1111/cei.12024
By:
- Kärner, J.;
- Meager, A.;
- Laan, M.;
- Maslovskaja, J.;
- Pihlap, M.;
- Remm, A.;
- Juronen, E.;
- Wolff, A. S. B.;
- Husebye, E. S.;
- Podkrajšek, K. T.;
- Bratanic, N.;
- Battelino, T.;
- Willcox, N.;
- Peterson, P.;
- Kisand, K.
Publication type:
Article
Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes.
Published in:
Clinical & Experimental Immunology, 2008, v. 154, n. 1, p. 141, doi. 10.1111/j.1365-2249.2008.03739.x
By:
- Meager, A.;
- Peterson, P.;
- Willcox, N.
Publication type:
Article
Anti-Cytokine Autoantibodies Preceding Onset of Autoimmune Polyendocrine Syndrome Type I Features in Early Childhood.
Published in:
Journal of Clinical Immunology, 2013, v. 33, n. 8, p. 1341, doi. 10.1007/s10875-013-9938-6
By:
- Wolff, A. S. B.;
- Sarkadi, A. K.;
- Maródi, L.;
- Kärner, J.;
- Orlova, E.;
- Oftedal, B. E. V.;
- Kisand, K.;
- Oláh, É.;
- Meloni, A.;
- Myhre, A. G.;
- Husebye, E. S.;
- Motaghedi, R.;
- Perheentupa, J.;
- Peterson, P.;
- Willcox, N.;
- Meager, A.
Publication type:
Article
Presentation of endogenous acetylcholine receptor antigen to a specific CD4+ T-cell line by a transfected B-cell line.
Published in:
Immunology, 1995, v. 86, n. 1, p. 116
By:
- Mulcahy, A. F.;
- Beeson, D. M. W.;
- Willcox, N.;
- Diamond, A. G.
Publication type:
Article
Greatly improved recovery of in vitro B-memory cell function after enzymic dispersion of immunized mouse spleens.
Published in:
Immunology, 1991, v. 74, n. 4, p. 600
By:
- Brown, A. N.;
- Willcox, H. N. A.
Publication type:
Article
Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.
Published in:
2005
By:
- Leite MI;
- Ströbel P;
- Jones M;
- Micklem K;
- Moritz R;
- Gold R;
- Niks EH;
- Berrih-Aknin S;
- Scaravilli F;
- Canelhas A;
- Marx A;
- Newsom-Davis J;
- Willcox N;
- Vincent A
Publication type:
Journal Article
Immunoglobulin M receptors on memory cells of immunoglobulin G antibody-forming cell clones.
Published in:
European Journal of Immunology, 1976, v. 6, n. 6, p. 443, doi. 10.1002/eji.1830060612
By:
- Abney, E. R.;
- Keeler, K. D.;
- Parkhouse, R. M. E.;
- Willcox, H. N. A.
Publication type:
Article
B cell tolerance induced by polymeric antigens V. Different avidities of primed and virgin precursor cells for paucivalent antigen.
Published in:
European Journal of Immunology, 1976, v. 6, n. 5, p. 379, doi. 10.1002/eji.1830060514
By:
- Willcox, H. N. A.;
- Klaus, G. G. B.
Publication type:
Article
B cell tolerance induced by polymeric antigens. III. Dissociation of antibody formation and memory generation in tolerant mice.
Published in:
European Journal of Immunology, 1975, v. 5, n. 10, p. 699, doi. 10.1002/eji.1830051010
By:
- Klaus, G. G. B.;
- Willcox, H. N. A.
Publication type:
Article
Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. II. Follow-up of clones relatively resistant to radioactive antigen suicide when initially selected.
Published in:
European Journal of Immunology, 1975, v. 5, n. 2, p. 131, doi. 10.1002/eji.1830050212
By:
- Willcox, H. N. A.;
- McMichael, A. J.
Publication type:
Article
Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. I. Recovery and escape from clonal dominance by suici resistant precursors.
Published in:
European Journal of Immunology, 1975, v. 5, n. 1, p. 58, doi. 10.1002/eji.1830050113
By:
- McMichael, A. J.;
- Willcox, N.
Publication type:
Article
Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis.
Published in:
2001
By:
- Buckley, Camilla;
- Douek, Daniel;
- Newsom-Davis, John;
- Vincent, Angela;
- Willcox, Nicholas;
- Buckley, C;
- Douek, D;
- Newsom-Davis, J;
- Vincent, A;
- Willcox, N
Publication type:
journal article
Early-onset myasthenia gravis: a recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a.
Published in:
1999
By:
- Hill, Marguerite;
- Beeson, David;
- Moss, Paul;
- Jacobson, Leslie;
- Bond, Alison;
- Corlett, Louise;
- Newsom-Davis, John;
- Vincent, Angela;
- Willcox, Nick;
- Hill, M;
- Beeson, D;
- Moss, P;
- Jacobson, L;
- Bond, A;
- Corlett, L;
- Newsom-Davis, J;
- Vincent, A;
- Willcox, N
Publication type:
journal article
Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells.
Published in:
Annals of Neurology, 1990, v. 28, n. 3, p. 312, doi. 10.1002/ana.410280303
By:
- Sommer, N.;
- Willcox, N.;
- Harcourt, G. C.;
- Newsom-Davis, J.
Publication type:
Article

Found: 34

An in Vitro Model for Disease-specific Immunotherapy in Myasthenia Gravis Using Soluble MHC Class II Bound to AChR-derived Peptidea.

Differential Recognition by T Cells of the P3A<sup>+</sup> and P3A<sup>-</sup> Isoforms of the Human Acetylcholine Receptor Alpha-Subunit.

Stimulation of Specific T Cells by Human A ChR Adsorbed to Immunomagnetic Particles.

Approaches for Studying the Pathogenic T Cells in Autoimmune Patientsa.

Blood and Thymic Lymphocyte Responses to Peptide Sequences of the Acetylcholine Receptor in Myasthenia Gravis.

Thymus dependence of the antibody response to tetanus toxoid in mice.

Spontaneous production of anti-IFN-α and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor.

Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1).

Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in Sardinian patients.

Scenarios for Autoimmunization of T and B Cells in Myasthenia Gravis.

Thymus, Thymoma, and Specific T Cells in Myasthenia Gravis<sup>a</sup>.

Muscle Nicotinic Acetylcholine Receptor mRNA Expression in Hyperplastic and Neoplastic Myasthenia Gravis Thymus<sup>a</sup>.

Production of Fab Fragments against the Human Acetylcholine Receptor from Myasthenia Gravis Thymus Lambda and Kappa Phage Libraries<sup>a</sup>.

Thymoma-An Expanded Cortical Epithelial Subset?

Development of an Adjuvant-Independent Model of Myasthenia Gravis in Mice.

Genetic Susceptibility to Myasthenia Gravis Studied by DNA Hybridization.

Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis.

Cell types required for anti-acetylcholine receptor antibody synthesis by cultured thymocytes and blood lymphocytes in myasthenia gravis.

Greatly increased autoantibody production in myasthenia gravis by thymocyte suspensions prepared with proteolytic enzymes.

IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis.

Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.

Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes.

Anti-Cytokine Autoantibodies Preceding Onset of Autoimmune Polyendocrine Syndrome Type I Features in Early Childhood.

Presentation of endogenous acetylcholine receptor antigen to a specific CD4<sup>+</sup> T-cell line by a transfected B-cell line.

Greatly improved recovery of <em>in vitro</em> B-memory cell function after enzymic dispersion of immunized mouse spleens.

Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.

Immunoglobulin M receptors on memory cells of immunoglobulin G antibody-forming cell clones.

B cell tolerance induced by polymeric antigens V. Different avidities of primed and virgin precursor cells for paucivalent antigen.

B cell tolerance induced by polymeric antigens. III. Dissociation of antibody formation and memory generation in tolerant mice.

Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. II. Follow-up of clones relatively resistant to radioactive antigen suicide when initially selected.

Radioactive antigen suicide of an anti-DNP (2,4-dinitrophenyl) clone. I. Recovery and escape from clonal dominance by suici resistant precursors.

Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis.

Early-onset myasthenia gravis: a recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a.

Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells.