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ALDH2 rs671 Is Associated With Elevated FPG, Reduced Glucose Clearance and Hepatic Insulin Resistance in Japanese Men.
Published in:
2021
By:
- Kageumi Takeno;
- Yoshifumi Tamura;
- Saori Kakehi;
- Hideyoshi Kaga;
- Ryuzo Kawamori;
- Hirotaka Watada;
- Takeno, Kageumi;
- Tamura, Yoshifumi;
- Kakehi, Saori;
- Kaga, Hideyoshi;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
journal article
Efficacy and Safety of 1:1 Fixed-Ratio Combination of Insulin Glargine and Lixisenatide Versus Lixisenatide in Japanese Patients With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs: The LixiLan JP-O1 Randomized Clinical Trial.
Published in:
2020
By:
- Hirotaka Watada;
- Akane Takami;
- Spranger, Robert;
- Atsushi Amano;
- Yasuhiro Hashimoto;
- Niemoeller, Elisabeth;
- Watada, Hirotaka;
- Takami, Akane;
- Amano, Atsushi;
- Hashimoto, Yasuhiro
Publication type:
journal article
Response to Comment on Mita et al. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial. Diabetes Care 2016;39:455-464.
Published in:
2016
By:
- Tomoya Mita;
- Naoto Katakami;
- Iichiro Shimomura;
- Hirotaka Watada;
- Mita, Tomoya;
- Katakami, Naoto;
- Shimomura, Iichiro;
- Watada, Hirotaka
Publication type:
Letter
Efficacy and safety of once‐weekly insulin icodec versus once‐daily basal insulin in Japanese individuals with type 2 diabetes: A subgroup analysis of the ONWARDS 1, 2 and 4 trials.
Published in:
Diabetes, Obesity & Metabolism, 2024, v. 26, n. 12, p. 5882, doi. 10.1111/dom.15960
By:
- Watada, Hirotaka;
- Ásbjörnsdóttir, Björg;
- Nishida, Tomoyuki;
- Nishimura, Rimei;
- Yamamoto, Yuiko;
- Yamauchi, Toshimasa;
- Kadowaki, Takashi
Publication type:
Article
Adipose tissue insulin resistance in young Japanese women is associated with metabolic abnormalities and dehydroepiandrosterone-sulfate.
Published in:
Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1390778
By:
- Motonori Sato;
- Yoshifumi Tamura;
- Hideyoshi Kaga;
- Nozomu Yamasaki;
- Satoshi Kadowaki;
- Daisuke Sugimoto;
- Takashi Nakagata;
- Yuki Someya;
- Yuya Nishida;
- Ryuzo Kawamori;
- Hirotaka Watada
Publication type:
Article
Comparison of insulin lispro mix 25 with insulin lispro mix 50 as an insulin starter in Asian patients with type 2 diabetes: a phase 4, open-label, randomized trial (CLASSIFY study).
Published in:
2017
By:
- Watada, Hirotaka;
- Su, Qing;
- Li, Peng Fei;
- Iwamoto, Noriyuki;
- Qian, Lei;
- Yang, Wen Ying
Publication type:
journal article
Efficacy of acarbose in different geographical regions of the world: analysis of a real-life database.
Published in:
Diabetes/Metabolism Research & Reviews, 2015, v. 31, n. 2, p. 155, doi. 10.1002/dmrr.2576
By:
- Weng, Jianping;
- Soegondo, Sidartawan;
- Schnell, Oliver;
- Sheu, Wayne H. ‐ H.;
- Grzeszczak, Wladyslaw;
- Watada, Hirotaka;
- Yamamoto, Noriyuki;
- Kalra, Sanjay
Publication type:
Article
Insulin resistance and muscle weakness are synergistic risk factors for silent lacunar infarcts: the Bunkyo Health Study.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00377-5
By:
- Someya, Yuki;
- Tamura, Yoshifumi;
- Kaga, Hideyoshi;
- Sugimoto, Daisuke;
- Kadowaki, Satoshi;
- Suzuki, Ruriko;
- Aoki, Shigeki;
- Hattori, Nobutaka;
- Motoi, Yumiko;
- Shimada, Kazunori;
- Daida, Hiroyuki;
- Ishijima, Muneaki;
- Kaneko, Kazuo;
- Nojiri, Shuko;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
Article
Identification of Ppy‐lineage cells as a novel origin of pancreatic ductal adenocarcinoma.
Published in:
Journal of Pathology, 2024, v. 263, p. 429, doi. 10.1002/path.6295
By:
- Pereye, Ofejiro Blessing;
- Nakagawa, Yuko;
- Sato, Takashi;
- Fukunaka, Ayako;
- Aoyama, Shuhei;
- Nishida, Yuya;
- Mizutani, Wakana;
- Kobayashi, Nanami;
- Morishita, Yohei;
- Oyama, Tetsunari;
- Kawabata‐Iwakawa, Reika;
- Watada, Hirotaka;
- Mizukami, Hiroki;
- Fukuda, Akihisa;
- Fujitani, Yoshio
Publication type:
Article
The Importance of Continuous Glucose Monitoringderived Metrics Beyond HbA1c for Optimal Individualized Glycemic Control.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 10, p. e3990, doi. 10.1210/clinem/dgac459
By:
- Hidenori Yoshii;
- Tomoya Mita;
- Naoto Katakami;
- Yosuke Okada;
- Takeshi Osonoi;
- Katsumi Aso;
- Akira Kurozumi;
- Satomi Wakasugi;
- Fumiya Sato;
- Ryota Ishii;
- Masahiko Gosho;
- Iichiro Shimomura;
- Hirotaka Watada
Publication type:
Article
Changes in Treatment Satisfaction Over 3 Years in Patients With Type 2 Diabetes After Initiating Second-line Treatment.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 9, p. 2424, doi. 10.1210/clinem/dgac420
By:
- Tomoya Mita;
- Naoto Katakami;
- Mitsuyoshi Takahara;
- Masaru Kawashima;
- Fumitaka Wada;
- Hiroki Akiyama;
- Naru Morita;
- Yoko Kidani;
- Toshitaka Yajima;
- Iichiro Shimomura;
- Hirotaka Watada
Publication type:
Article
Prevalence and Features of Impaired Glucose Tolerance in Young Underweight Japanese Women.
Published in:
2021
By:
- Motonori Sato;
- Yoshifumi Tamura;
- Takashi Nakagata;
- Yuki Someya;
- Hideyoshi Kaga;
- Nozomu Yamasaki;
- Mai Kiya;
- Satoshi Kadowaki;
- Daisuke Sugimoto;
- Hiroaki Satoh;
- Ryuzo Kawamori;
- Hirotaka Watada;
- Sato, Motonori;
- Tamura, Yoshifumi;
- Nakagata, Takashi;
- Someya, Yuki;
- Kaga, Hideyoshi;
- Yamasaki, Nozomu;
- Kiya, Mai;
- Kadowaki, Satoshi
Publication type:
journal article
Adipose Insulin Resistance and Decreased Adiponectin Are Correlated With Metabolic Abnormalities in Nonobese Men.
Published in:
2021
By:
- Mai Kiya;
- Yoshifumi Tamura;
- Kageumi Takeno;
- Yuki Someya;
- Saori Kakehi;
- Motonori Sato;
- Nozomu Yamasaki;
- Satoshi Kadowaki;
- Ruriko Suzuki;
- Yasuhiko Furukawa;
- Daisuke Sugimoto;
- Hideyoshi Kaga;
- Takashi Funayama;
- Miho Nishitani-Yokoyama;
- Kazunori Shimada;
- Hiroyuki Daida;
- Shigeki Aoki;
- Hiroaki Satoh;
- Ryuzo Kawamori;
- Hirotaka Watada
Publication type:
journal article
Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program).
Published in:
Cardiovascular Diabetology, 2018, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12933-018-0787-8
By:
- Kosiborod, Mikhail;
- Gomes, Marilia B.;
- Nicolucci, Antonio;
- Pocock, Stuart;
- Rathmann, Wolfgang;
- Shestakova, Marina V.;
- Watada, Hirotaka;
- Shimomura, Iichiro;
- Chen, Hungta;
- Cid-Ruzafa, Javier;
- Fenici, Peter;
- Hammar, Niklas;
- Surmont, Filip;
- Tang, Fengming;
- Khunti, Kamlesh
Publication type:
Article
Global use of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes. Results from DISCOVER.
Published in:
BMC Endocrine Disorders, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12902-022-01026-2
By:
- Arnold, Suzanne V.;
- Tang, Fengming;
- Cooper, Andrew;
- Chen, Hungta;
- Gomes, Marilia B.;
- Rathmann, Wolfgang;
- Shimomura, Iichiro;
- Vora, Jiten;
- Watada, Hirotaka;
- Khunti, Kamlesh;
- Kosiborod, Mikhail
Publication type:
Article
Angiotensin II receptor blocker provides pancreatic β-cell protection independent of blood pressure lowering in diabetic db/db mice.
Published in:
Acta Pharmacologica Sinica, 2007, v. 28, n. 2, p. 246, doi. 10.1111/j.1745-7254.2007.00492.x
By:
- Jia-qing Shao;
- Iwashita, Noseki;
- Hong Du;
- Yang-tian Wang;
- Yan-yan Wang;
- Ming Zhao;
- Jian Wang;
- Watada, Hirotaka;
- Kawamori, Ryuzo
Publication type:
Article
Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 8, p. 3634, doi. 10.1172/JCI69866
By:
- Nayumi Shigihara;
- Ayako Fukunaka;
- Akemi Hara;
- Koji Komiya;
- Akira Honda;
- Toyoyoshi Uchida;
- Hiroko Abe;
- Yukiko Toyofuku;
- Motoyuki Tamaki;
- Takeshi Ogihara;
- Takeshi Miyatsuka;
- Hiddinga, Henry J.;
- Setsuya Sakagashira;
- Masato Koike;
- Yasuo Uchiyama;
- Tamotsu Yoshimori;
- Eberhardt, Norman L.;
- Yoshio Fujitani;
- Hirotaka Watada
Publication type:
Article
Randomized, double-blind, placebo-controlled phase 3 study of bardoxolone methyl in patients with diabetic kidney disease: design and baseline characteristics of the AYAME study.
Published in:
Nephrology Dialysis Transplantation, 2023, v. 38, n. 5, p. 1204, doi. 10.1093/ndt/gfac242
By:
- Nangaku, Masaomi;
- Takama, Hirotaka;
- Ichikawa, Tomohiro;
- Mukai, Kazuya;
- Kojima, Masahiro;
- Suzuki, Yusuke;
- Watada, Hirotaka;
- Wada, Takashi;
- Ueki, Kohjiro;
- Narita, Ichiei;
- Kashihara, Naoki;
- Kadowaki, Takashi;
- Hase, Hiroki;
- Akizawa, Tadao
Publication type:
Article
Endurance Runners with Intramyocellular Lipid Accumulation and High Insulin Sensitivity Have Enhanced Expression of Genes Related to Lipid Metabolism in Muscle.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 12, p. 3951, doi. 10.3390/jcm9123951
By:
- Kakehi, Saori;
- Tamura, Yoshifumi;
- Takeno, Kageumi;
- Ikeda, Shin-ichi;
- Ogura, Yuji;
- Saga, Norio;
- Miyatsuka, Takeshi;
- Naito, Hisashi;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
Article
Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice.
Published in:
Physiological Reports, 2022, v. 10, n. 18, p. 1, doi. 10.14814/phy2.15478
By:
- Yamamoto, Hiro;
- Eshima, Hiroaki;
- Kakehi, Saori;
- Kawamori, Ryuzo;
- Watada, Hirotaka;
- Tamura, Yoshifumi
Publication type:
Article
Defective autophagy in vascular smooth muscle cells enhances the healing of abdominal aortic aneurysm.
Published in:
Physiological Reports, 2021, v. 9, n. 17, p. 1, doi. 10.14814/phy2.15000
By:
- Mochida, Akihiro;
- Mita, Tomoya;
- Azuma, Kosuke;
- Osonoi, Yusuke;
- Masuyama, Atsushi;
- Nakajima, Kenichi;
- Goto, Hiromasa;
- Nishida, Yuya;
- Miyatsuka, Takeshi;
- Mitsumata, Masako;
- Watada, Hirotaka
Publication type:
Article
Effects of blood flow restriction on muscle size and gene expression in muscle during immobilization: A pilot study.
Published in:
Physiological Reports, 2020, v. 8, n. 14, p. 1, doi. 10.14814/phy2.14516
By:
- Kakehi, Saori;
- Tamura, Yoshifumi;
- Kubota, Atsushi;
- Takeno, Kageumi;
- Kawaguchi, Minako;
- Sakuraba, Keishoku;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
Article
Phase I/IIa Feasibility Trial of Autologous Quality- and Quantity-Cultured Peripheral Blood Mononuclear Cell Therapy for Non-Healing Extremity Ulcers.
Published in:
Stem Cells Translational Medicine, 2022, v. 11, n. 2, p. 146, doi. 10.1093/stcltm/szab018
By:
- Tanaka, Rica;
- Fujimura, Satoshi;
- Kado, Makiko;
- Fukuta, Taro;
- Arita, Kayo;
- Hirano-Ito, Rie;
- Mita, Tomoya;
- Watada, Hirotaka;
- Kato, Yoshiteru;
- Miyauchi, Katsumi;
- Mizuno, Hiroshi
Publication type:
Article
Ex vivo conditioning of peripheral blood mononuclear cells of diabetic patients promotes vasculogenic wound healing.
Published in:
Stem Cells Translational Medicine, 2021, v. 10, n. 6, p. 895, doi. 10.1002/sctm.20-0309
By:
- Tanaka, Rica;
- Ito‐Hirano, Rie;
- Fujimura, Satoshi;
- Arita, Kayo;
- Hagiwara, Hiroko;
- Mita, Tomoya;
- Itoh, Masayoshi;
- Kawaji, Hideya;
- Ogawa, Takasuke;
- Watada, Hirotaka;
- Masuda, Haruchika;
- Asahara, Takayuki;
- Mizuno, Hiroshi
Publication type:
Article
Quality‐Quantity Control Culture Enhances Vasculogenesis and Wound Healing Efficacy of Human Diabetic Peripheral Blood CD34+ Cells.
Published in:
Stem Cells Translational Medicine, 2018, v. 7, n. 5, p. 428, doi. 10.1002/sctm.17-0043
By:
- Tanaka, Rica;
- Masuda, Haruchika;
- Fujimura, Satoshi;
- Ito‐Hirano, Rie;
- Arita, Kayo;
- Kakinuma, Yusuke;
- Hagiwara, Hiroko;
- Kado, Makiko;
- Hayashi, Ayato;
- Mita, Tomoya;
- Ogawa, Takasuke;
- Watada, Hirotaka;
- Mizuno, Hiroshi;
- Sawada, Naoki;
- Asahara, Takayuki
Publication type:
Article
Zinc and iron dynamics in human islet amyloid polypeptide-induced diabetes mouse model.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-30498-y
By:
- Fukunaka, Ayako;
- Shimura, Mari;
- Ichinose, Takayuki;
- Pereye, Ofejiro B.;
- Nakagawa, Yuko;
- Tamura, Yasuko;
- Mizutani, Wakana;
- Inoue, Ryota;
- Inoue, Takato;
- Tanaka, Yuto;
- Sato, Takashi;
- Saitoh, Tatsuya;
- Fukada, Toshiyuki;
- Nishida, Yuya;
- Miyatsuka, Takeshi;
- Shirakawa, Jun;
- Watada, Hirotaka;
- Matsuyama, Satoshi;
- Fujitani, Yoshio
Publication type:
Article
STAT3 suppression and β-cell ablation enhance α-to-β reprogramming mediated by Pdx1.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-25941-5
By:
- Wakabayashi, Yuka;
- Miyatsuka, Takeshi;
- Miura, Masaki;
- Himuro, Miwa;
- Taguchi, Tomomi;
- Iida, Hitoshi;
- Nishida, Yuya;
- Fujitani, Yoshio;
- Watada, Hirotaka
Publication type:
Article
Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population.
Published in:
Journal of Human Genetics, 2013, v. 58, n. 7, p. 490, doi. 10.1038/jhg.2013.28
By:
- Fukuda, Hisashi;
- Imamura, Minako;
- Tanaka, Yasushi;
- Iwata, Minoru;
- Hirose, Hiroshi;
- Kaku, Kohei;
- Maegawa, Hiroshi;
- Watada, Hirotaka;
- Tobe, Kazuyuki;
- Kashiwagi, Atsunori;
- Kawamori, Ryuzo;
- Maeda, Shiro
Publication type:
Article
Serotonin regulates pancreatic beta cell mass during pregnancy.
Published in:
Nature Medicine, 2010, v. 16, n. 7, p. 804, doi. 10.1038/nm.2173
By:
- Hail Kim;
- Toyofuku, Yukiko;
- Lynn, Francis C;
- Chak, Eric;
- Uchida, Toyoyoshi;
- Mizukami, Hiroki;
- Fujitani, Yoshio;
- Kawamori, Ryuzo;
- Miyatsuka, Takeshi;
- Kosaka, Yasuhiro;
- Yang, Katherine;
- Honig, Gerard;
- van der Hart, Marieke;
- Kishimoto, Nina;
- Wang, Juehu;
- Yagihashi, Soroku;
- Tecott, Laurence H;
- Watada, Hirotaka;
- German, Michael S.
Publication type:
Article
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
Published in:
Nature Genetics, 2010, v. 42, n. 10, p. 864, doi. 10.1038/ng.660
By:
- Yamauchi, Toshimasa;
- Hara, Kazuo;
- Maeda, Shiro;
- Yasuda, Kazuki;
- Takahashi, Atsushi;
- Horikoshi, Momoko;
- Nakamura, Masahiro;
- Fujita, Hayato;
- Grarup, Niels;
- Cauchi, Stephane;
- Ng, Daniel P. K.;
- Ma, Ronald C. W.;
- Tsunoda, Tatsuhiko;
- Kubo, Michiaki;
- Watada, Hirotaka;
- Maegawa, Hiroshi;
- Okada-Iwabu, Miki;
- Iwabu, Masato;
- Shojima, Nobuhiro;
- Hyoung Doo Shin
Publication type:
Article
Association Between Expression of FABPpm in Skeletal Muscle and Insulin Sensitivity in Intramyocellular Lipid-Accumulated Nonobese Men.
Published in:
2014
By:
- Kawaguchi, Minako;
- Tamura, Yoshifumi;
- Kakehi, Saori;
- Takeno, Kageumi;
- Sakurai, Yuko;
- Watanabe, Takahiro;
- Funayama, Takashi;
- Sato, Fumihiko;
- Ikeda, Shinichi;
- Ogura, Yuji;
- Saga, Norio;
- Naito, Hisashi;
- Fujitani, Yoshio;
- Kanazawa, Akio;
- Kawamori, Ryuzo;
- Watada, Hirotaka
Publication type:
Journal Article
Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population.
Published in:
2013
By:
- Imamura, Minako;
- Shigemizu, Daichi;
- Tsunoda, Tatsuhiko;
- Iwata, Minoru;
- Maegawa, Hiroshi;
- Watada, Hirotaka;
- Hirose, Hiroshi;
- Tanaka, Yasushi;
- Tobe, Kazuyuki;
- Kaku, Kohei;
- Kashiwagi, Atsunori;
- Kawamori, Ryuzo;
- Maeda, Shiro
Publication type:
Journal Article
Dietary characteristics of urban community-dwelling older adults with low muscle mass: the bunkyo health study: a cross-sectional study.
Published in:
BMC Geriatrics, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12877-024-05218-4
By:
- Muroga, Yukiko;
- Kaga, Hideyoshi;
- Bui, Thu Hien;
- Sugimoto, Mari;
- Someya, Yuki;
- Kakehi, Saori;
- Tabata, Hiroki;
- Naito, Hitoshi;
- Abudurezake, Abulaiti;
- Shi, Huicong;
- Otsuka, Hikaru;
- Yoshizawa, Yasuyo;
- Kawamori, Ryuzo;
- Watada, Hirotaka;
- Tamura, Yoshifumi
Publication type:
Article
Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.
Published in:
PLoS Genetics, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pgen.1006950
By:
- Fukunaka, Ayako;
- Fukada, Toshiyuki;
- Bhin, Jinhyuk;
- Suzuki, Luka;
- Tsuzuki, Takamasa;
- Takamine, Yuri;
- Bin, Bum-Ho;
- Yoshihara, Toshinori;
- Ichinoseki-Sekine, Noriko;
- Naito, Hisashi;
- Miyatsuka, Takeshi;
- Takamiya, Shinzaburo;
- Sasaki, Tsutomu;
- Inagaki, Takeshi;
- Kitamura, Tadahiro;
- Kajimura, Shingo;
- Watada, Hirotaka;
- Fujitani, Yoshio
Publication type:
Article
Clinical significance and management of insomnia.
Published in:
Sleep & Biological Rhythms, 2011, v. 9, n. 2, p. 63, doi. 10.1111/j.1479-8425.2011.00496.x
By:
- UCHIYAMA, Makoto;
- INOUE, Yuichi;
- UCHIMURA, Naohisa;
- KAWAMORI, Ryuzo;
- KURABAYASHI, Masahiko;
- KARIO, Kazuomi;
- WATADA, Hirotaka
Publication type:
Article
Novel time-resolved reporter mouse reveals spatial and transcriptional heterogeneity during alpha cell differentiation.
Published in:
Diabetologia, 2024, v. 67, n. 1, p. 156, doi. 10.1007/s00125-023-06028-w
By:
- Himuro, Miwa;
- Wakabayashi, Yuka;
- Taguchi, Tomomi;
- Katahira, Takehiro;
- Suzuki, Luka;
- Iida, Hitoshi;
- Ogihara, Takeshi;
- Nishida, Yuya;
- Sasaki, Shugo;
- Lynn, Francis C.;
- Hiraoka, Yuichi;
- Oshima, Shigeru;
- Okamoto, Ryuichi;
- Fujitani, Yoshio;
- Watada, Hirotaka;
- Miyatsuka, Takeshi
Publication type:
Article
Continuous glucose monitoring-derived time in range and CV are associated with altered tissue characteristics of the carotid artery wall in people with type 2 diabetes.
Published in:
Diabetologia, 2023, v. 66, n. 12, p. 2356, doi. 10.1007/s00125-023-06013-3
By:
- Mita, Tomoya;
- Katakami, Naoto;
- Okada, Yosuke;
- Yoshii, Hidenori;
- Osonoi, Takeshi;
- Nishida, Keiko;
- Shiraiwa, Toshihiko;
- Kurozumi, Akira;
- Taya, Naohiro;
- Wakasugi, Satomi;
- Sato, Fumiya;
- Ishii, Ryota;
- Gosho, Masahiko;
- Shimomura, Iichiro;
- Watada, Hirotaka
Publication type:
Article
Spatial and transcriptional heterogeneity of pancreatic beta cell neogenesis revealed by a time-resolved reporter system.
Published in:
Diabetologia, 2022, v. 65, n. 5, p. 811, doi. 10.1007/s00125-022-05662-0
By:
- Sasaki, Shugo;
- Lee, Michelle Y. Y.;
- Wakabayashi, Yuka;
- Suzuki, Luka;
- Winata, Helena;
- Himuro, Miwa;
- Matsuoka, Taka-aki;
- Shimomura, Iichiro;
- Watada, Hirotaka;
- Lynn, Francis C.;
- Miyatsuka, Takeshi
Publication type:
Article
Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice.
Published in:
Diabetologia, 2021, v. 64, n. 12, p. 2803, doi. 10.1007/s00125-021-05560-x
By:
- Fukaishi, Takahiro;
- Nakagawa, Yuko;
- Fukunaka, Ayako;
- Sato, Takashi;
- Hara, Akemi;
- Nakao, Keiko;
- Saito, Michiko;
- Kohno, Kenji;
- Miyatsuka, Takeshi;
- Tamaki, Motoyuki;
- Matsuhisa, Munehide;
- Matsuoka, Taka-aki;
- Yamada, Tetsuya;
- Watada, Hirotaka;
- Fujitani, Yoshio
Publication type:
Article
Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice.
Published in:
Diabetologia, 2015, v. 58, n. 11, p. 2582, doi. 10.1007/s00125-015-3728-z
By:
- Sasaki, Shugo;
- Miyatsuka, Takeshi;
- Matsuoka, Taka-aki;
- Takahara, Mitsuyoshi;
- Yamamoto, Yuichi;
- Yasuda, Tetsuyuki;
- Kaneto, Hideaki;
- Fujitani, Yoshio;
- German, Michael;
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Article
Relationship between frequency of hypoglycemic episodes and changes in carotid atherosclerosis in insulin-treated patients with type 2 diabetes mellitus.
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Scientific Reports, 2017, p. 39965, doi. 10.1038/srep39965
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- Watada, Hirotaka
Publication type:
Article
Effects of alcohol abstinence on glucose metabolism in Japanese men with elevated fasting glucose: A pilot study.
Published in:
Scientific Reports, 2017, p. 40277, doi. 10.1038/srep40277
By:
- Funayama, Takashi;
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- Takeno, Kageumi;
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Publication type:
Article
Differences in imeglimin response in subgroups of patients with type 2 diabetes stratified by data‐driven cluster analysis: A post‐hoc analysis of imeglimin clinical trial data.
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Diabetes, Obesity & Metabolism, 2024, v. 26, n. 9, p. 3732, doi. 10.1111/dom.15716
By:
- Hagi, Katsuhiko;
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Article
HbA1c trajectories over 3 years in people with type 2 diabetes starting second‐line glucose‐lowering therapy: The prospective global DISCOVER study.
Published in:
Diabetes, Obesity & Metabolism, 2023, v. 25, n. 7, p. 1890, doi. 10.1111/dom.15050
By:
- Bongaerts, Brenda;
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- Cooper, Andrew;
- Fenici, Peter;
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- Ji, Linong;
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- Medina, Jesús;
- Nicolucci, Antonio;
- Shestakova, Marina V.;
- Watada, Hirotaka;
- Rathmann, Wolfgang
Publication type:
Article
Treatment patterns and glycated haemoglobin levels over 36 months in individuals with type 2 diabetes initiating second‐line glucose‐lowering therapy: The global DISCOVER study.
Published in:
Diabetes, Obesity & Metabolism, 2023, v. 25, n. 1, p. 46, doi. 10.1111/dom.14842
By:
- Charbonnel, Bernard H.;
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- Medina, Jesús;
- Nicolucci, Antonio;
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- Tang, Fengming;
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Publication type:
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Interconnection between cardiovascular, renal and metabolic disorders: A narrative review with a focus on Japan.
Published in:
Diabetes, Obesity & Metabolism, 2022, v. 24, n. 12, p. 2283, doi. 10.1111/dom.14829
By:
- Kadowaki, Takashi;
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Publication type:
Article
Cover Image, Volume 24, Issue 12.
Published in:
Diabetes, Obesity & Metabolism, 2022, v. 24, n. 12, p. 1, doi. 10.1111/dom.14114
By:
- Kadowaki, Takashi;
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- Node, Koichi;
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- Wada, Jun
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Article
Factors associated with weight loss in people with overweight or obesity living with type 2 diabetes mellitus: Insights from the global DISCOVER study.
Published in:
Diabetes, Obesity & Metabolism, 2022, v. 24, n. 9, p. 1734, doi. 10.1111/dom.14745
By:
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- Tang, Fengming;
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- Ji, Linong;
- Gomes, Marilia B.;
- Watada, Hirotaka;
- Vora, Jiten;
- Malik, Ali O.;
- Kosiborod, Mikhail;
- Arnold, Suzanne V.
Publication type:
Article
Efficacy and safety of imeglimin add‐on to insulin monotherapy in Japanese patients with type 2 diabetes (TIMES 3): A randomized, double‐blind, placebo‐controlled phase 3 trial with a 36‐week open‐label extension period.
Published in:
Diabetes, Obesity & Metabolism, 2022, v. 24, n. 5, p. 838, doi. 10.1111/dom.14642
By:
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Relationship between blood glucose variability in ambulatory glucose profile and standardized continuous glucose monitoring metrics: Subanalysis of a prospective cohort study.
Published in:
Diabetes, Obesity & Metabolism, 2022, v. 24, n. 1, p. 82, doi. 10.1111/dom.14550
By:
- Tokutsu, Akemi;
- Okada, Yosuke;
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Publication type:
Article

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