Works by Wätjen, Wim

Results: 37

Hibiscus sabdariffa L. extract prolongs lifespan and protects against amyloid-β toxicity in Caenorhabditis elegans: involvement of the FoxO and Nrf2 orthologues DAF-16 and SKN-1.

Published in:

European Journal of Nutrition, 2020, v. 59, n. 1, p. 137, doi. 10.1007/s00394-019-01894-w

By:

Koch, Karoline;
Weldle, Nora;
Baier, Sabrina;
Büchter, Christian;
Wätjen, Wim

Publication type:

Article

Isoxanthohumol, a constituent of hop ( Humulus lupulus L.), increases stress resistance in Caenorhabditis elegans dependent on the transcription factor DAF-16.

Published in:

European Journal of Nutrition, 2016, v. 55, n. 1, p. 257, doi. 10.1007/s00394-015-0843-z

By:

Büchter, Christian;
Havermann, Susannah;
Koch, Karoline;
Wätjen, Wim

Publication type:

Article

Polymer Conjugates of Photoinducible CO-Releasing Molecules.

Published in:

European Journal of Inorganic Chemistry, 2011, v. 2011, n. 29, p. 4571, doi. 10.1002/ejic.201100545

By:

Brückmann, Nadine E.;
Wahl, Michaela;
Reiß, Guido J.;
Kohns, Marbod;
Wätjen, Wim;
Kunz, Peter C.

Publication type:

Article

Controversy on health-based guidance values for bisphenol A—the need of criteria for studies that serve as a basis for risk assessment.

Published in:

Archives of Toxicology, 2024, v. 98, n. 7, p. 1967, doi. 10.1007/s00204-024-03778-3

By:

Leist, Marcel;
Buettner, Andrea;
Diel, Patrick;
Eisenbrand, Gerhard;
Epe, Bernd;
Först, Petra;
Grune, Tilman;
Haller, Dirk;
Heinz, Volker;
Hellwig, Michael;
Humpf, Hans-Ulrich;
Jäger, Henry;
Kulling, Sabine E.;
Mally, Angela;
Marko, Doris;
Nöthlings, Ute;
Röhrdanz, Elke;
Spranger, Joachim;
Vieths, Stefan;
Wätjen, Wim

Publication type:

Article

Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 6, p. 11895, doi. 10.3390/ijms140611895

By:

Büchter, Christian;
Ackermann, Daniela;
Havermann, Susannah;
Honnen, Sebastian;
Chovolou, Yvonni;
Fritz, Gerhard;
Kampkötter, Andreas;
Wätjen, Wim

Publication type:

Article

Safety Assessment of Vitamin D and Its Photo-Isomers in UV-Irradiated Baker’s Yeast.

Published in:

Foods, 2021, v. 10, n. 12, p. 1, doi. 10.3390/foods10123142

By:

Schümmer, Tobias;
Stangl, Gabriele I.;
Wätjen, Wim

Publication type:

Article

Insects for Food and Feed-Safety Aspects Related to Mycotoxins and Metals.

Published in:

Foods, 2019, v. 8, n. 8, p. 288, doi. 10.3390/foods8080288

By:

Schrögel, Pamela;
Wätjen, Wim

Publication type:

Article

Catalase overexpression impairs TNF-α induced NF-κB activation and sensitizes MCF-7 cells against TNF-α.

Published in:

Journal of Cellular Biochemistry, 2008, v. 103, n. 5, p. 1497, doi. 10.1002/jcb.21538

By:

Lüpertz, Regine;
Chovolou, Yvonni;
Kampkötter, Andreas;
Wätjen, Wim;
Kahl, Regine

Publication type:

Article

Modulation of the Nrf2 signalling pathway in Hct116 colon carcinoma cells by baicalein and its methylated derivative negletein.

Published in:

Pharmaceutical Biology, 2016, v. 54, n. 9, p. 1491, doi. 10.3109/13880209.2015.1104703

By:

Havermann, Susannah;
Chovolou, Yvonni;
Humpf, Hans-Ulrich;
Wätjen, Wim

Publication type:

Article

Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation.

Published in:

Molecular Nutrition & Food Research, 2009, v. 53, n. 4, p. 431, doi. 10.1002/mnfr.200700428

By:

Wätjen, Wim;
Debbab, Abdessamad;
Hohlfeld, Anke;
Chovolou, Yvonni;
Kampkötter, Andreas;
Edrada, Ru Angelie;
Ebel, Rainer;
Hakiki, Abdelhak;
Mosaddak, Mahjouba;
Totzke, Frank;
Kubbutat, Michael H. G.;
Proksch, Peter

Publication type:

Article

Association between vitamin D status and eryptosis–results from the German National Cohort Study.

Published in:

Annals of Hematology, 2023, v. 102, n. 6, p. 1351, doi. 10.1007/s00277-023-05239-w

By:

Ewendt, Franz;
Schmitt, Marvin;
Kluttig, Alexander;
Kühn, Julia;
Hirche, Frank;
Kraus, Frank B.;
Ludwig-Kraus, Beatrice;
Mikolajczyk, Rafael;
Wätjen, Wim;
Bürkner, Paul-Christian;
Föller, Michael;
Stangl, Gabriele I.

Publication type:

Article

Caenorhabditis elegans as Model System in Pharmacology and Toxicology: Effects of Flavonoids on Redox-Sensitive Signalling Pathways and Ageing.

Published in:

Scientific World Journal, 2014, p. 1, doi. 10.1155/2014/920398

By:

Koch, Karoline;
Havermann, Susannah;
Büchter, Christian;
Wätjen, Wim

Publication type:

Article

Cytotoxic effects of the anthraquinone derivatives 1′-deoxyrhodoptilometrin and ( S)-(−)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1485, doi. 10.1007/s00204-016-1787-7

By:

Wätjen, Wim;
Ebada, Sherif;
Bergermann, Anja;
Chovolou, Yvonni;
Totzke, Frank;
Kubbutat, Michael;
Lin, Wenhan;
Proksch, Peter

Publication type:

Article

The Brassica-derived phytochemical indolo[3,2- b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation.

Published in:

Archives of Toxicology, 2017, v. 91, n. 2, p. 967, doi. 10.1007/s00204-016-1672-4

By:

Faust, Dagmar;
Nikolova, Teodora;
Kaina, Bernd;
Dietrich, Cornelia;
Wätjen, Wim

Publication type:

Article

Epigallocatechin gallate (EGCG) inhibits adhesion and migration of neural progenitor cells in vitro.

Published in:

Archives of Toxicology, 2017, v. 91, n. 2, p. 827, doi. 10.1007/s00204-016-1709-8

By:

Barenys, Marta;
Gassmann, Kathrin;
Baksmeier, Christine;
Heinz, Sabrina;
Schmuck, Martin;
Temme, Thomas;
Bendt, Farina;
Zschauer, Tim-Christian;
Rockel, Thomas;
Unfried, Klaus;
Sundaram, Sivaraj;
Heuer, Heike;
Fritsche, Ellen;
Reverte, Ingrid;
Colomina, Maria;
Wätjen, Wim

Publication type:

Article

Effects of the flavonoids kaempferol and fisetin on thermotolerance, oxidative stress and FoxO transcription factor DAF-16 in the model organism Caenorhabditis elegans.

Published in:

Archives of Toxicology, 2007, v. 81, n. 12, p. 849, doi. 10.1007/s00204-007-0215-4

By:

Kampkötter, Andreas;
Gombitang Nkwonkam, Christiane;
Zurawski, Ruben;
Timpel, Claudia;
Chovolou, Yvonni;
Wätjen, Wim;
Kahl, Regine

Publication type:

Article

Cadmium-induced apoptosis in murine fibroblasts is suppressed by Bcl-2.

Published in:

Archives of Toxicology, 2001, v. 75, n. 6, p. 313, doi. 10.1007/s002040100236

By:

Biagioli, Marta;
Wätjen, Wim;
Beyersmann, Detmar;
Zoncu, Roberto;
Cappellini, Chiara;
Ragghianti, Matilde;
Cremisi, Federico;
Bucci, Stefania

Publication type:

Article

Occurrence of Nine Pyrrolizidine Alkaloids in Senecio vulgaris L. Depending on Developmental Stage and Season.

Published in:

Plants (2223-7747), 2019, v. 8, n. 3, p. 54, doi. 10.3390/plants8030054

By:

Beschow, Heidrun;
Flade, Jens;
Plescher, Andreas;
Wätjen, Wim;
Wensch-Dorendorf, Monika

Publication type:

Article

Polygonum multiflorum Extract Exerts Antioxidative Effects and Increases Life Span and Stress Resistance in the Model Organism Caenorhabditis elegans via DAF-16 and SIR-2.1.

Published in:

Plants (2223-7747), 2018, v. 7, n. 3, p. 60, doi. 10.3390/plants7030060

By:

Saier, Christina;
Büchter, Christian;
Koch, Karoline;
Wätjen, Wim

Publication type:

Article

Cannabidiol in Foods and Food Supplements: Evaluation of Health Risks and Health Claims.

Published in:

Nutrients, 2025, v. 17, n. 3, p. 489, doi. 10.3390/nu17030489

By:

Engeli, Barbara E.;
Lachenmeier, Dirk W.;
Diel, Patrick;
Guth, Sabine;
Villar Fernandez, Maria A.;
Roth, Angelika;
Lampen, Alfonso;
Cartus, Alexander T.;
Wätjen, Wim;
Hengstler, Jan G.;
Mally, Angela

Publication type:

Article

Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue).

Published in:

Antioxidants, 2018, v. 7, n. 12, p. 192, doi. 10.3390/antiox7120192

By:

Saier, Christina;
Gommlich, Inge;
Hiemann, Volker;
Baier, Sabrina;
Koch, Karoline;
Horn, Gert;
Kowalewsky, Tanja;
Bartelt, Jörg;
Seemann, Maria;
Wätjen, Wim

Publication type:

Article

Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge <italic>Stylissa carteri</italic>.

Published in:

Zeitschrift für Naturforschung. Section C: A Journal of Biosciences, 2018, v. 73, n. 5/6, p. 199, doi. 10.1515/znc-2017-0161

By:

Hamed, Ashraf N.E.;
Schmitz, Roland;
Bergermann, Anja;
Totzke, Frank;
Kubbutat, Michael;
Müller, Werner E.G.;
Youssef, Diaa T.A.;
Bishr, Mokhtar M.;
Kamel, Mohamed S.;
Edrada-Ebel, RuAngelie;
Wätjen, Wim;
Proksch, Peter

Publication type:

Article

Acetaldehyde as a Food Flavoring Substance: Aspects of Risk Assessment.

Published in:

Molecular Nutrition & Food Research, 2023, v. 67, n. 23, p. 1, doi. 10.1002/mnfr.202200661

By:

Cartus, Alexander T.;
Lachenmeier, Dirk W.;
Guth, Sabine;
Roth, Angelika;
Baum, Matthias;
Diel, Patrick;
Eisenbrand, Gerhard;
Engeli, Barbara;
Hellwig, Michael;
Humpf, Hans‐Ulrich;
Joost, Hans‐Georg;
Kulling, Sabine E.;
Lampen, Alfonso;
Marko, Doris;
Steinberg, Pablo;
Wätjen, Wim;
Hengstler, Jan G.;
Mally, Angela

Publication type:

Article

Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 6, p. 1007, doi. 10.1111/jphp.13074

By:

Koch, Karoline;
Schulz, Gabriel;
Döring, Wera;
Büchter, Christian;
Havermann, Susannah;
Mutiso, Patrick Chalo;
Passreiter, Claus;
Wätjen, Wim

Publication type:

Article

The resveratrol derivatives trans-3,5-dimethoxy-4-fluoro-4′-hydroxystilbene and trans-2,4′,5-trihydroxystilbene decrease oxidative stress and prolong lifespan in Caenorhabditis elegans.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 1, p. 73, doi. 10.1111/jphp.12657

By:

Fischer, Nadine;
Büchter, Christian;
Koch, Karoline;
Albert, Sabrina;
Csuk, René;
Wätjen, Wim

Publication type:

Article

Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 9, p. 1393, doi. 10.1111/jphp.12107

By:

Limper, Christian;
Wang, Yao;
Ruhl, Sven;
Wang, Zhiqiang;
Lou, Yijia;
Totzke, Frank;
Kubbutat, Michael H.G.;
Chovolou, Yvonni;
Proksch, Peter;
Wätjen, Wim

Publication type:

Article

Hexa-, hepta- and nonaprenylhydroquinones isolated from marine sponges Sarcotragus muscarumand Ircinia fasciculatainhibit NF-κB signalling in H4IIE cells.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 7, p. 919, doi. 10.1211/jpp/61.07.0011

By:

Wim Wätjen;
Annika Putz;
Yvonni Chovolou;
Andreas Kampkötter;
Frank Totzke;
Michael Kubbutat;
Peter Proksch;
Belma Konuklugil

Publication type:

Article

Polyphenols from plants used in traditional Indonesian medicine (Jamu): uptake and antioxidative effects in rat H4IIE hepatoma cells.

Published in:

Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 2, p. 233, doi. 10.1211/0022357055317

By:

Steffan, Bärbel;
Wätjen, Wim;
Michels, Gudrun;
Niering, Petra;
Wray, Victor;
Ebel, Rainer;
Edrada, RuAngelie;
Kahl, Regine;
Proksch, Peter

Publication type:

Article

Pyrrolizidinalkaloide in Senecio vulgaris L. in Abhängigkeit vom Entwicklungsstadium unter Betrachtung verschiedener Jahreszeiten.

Published in:

Journal of Cultivated Plants / Journal für Kulturpflanzen, 2020, v. 72, n. 4, p. 103, doi. 10.5073/JfK.2020.04.07

By:

Flade, Jens;
Beschow, Heidrun;
Plescher, Andreas;
Wätjen, Wim

Publication type:

Article

Antioxidative effects of a Humulus lupulus extract in Caenorhabditis elegans.

Published in:

Lebensmittelchemie, 2021, v. 75, p. S1-104, doi. 10.1002/lemi.202156007

By:

Glaser, Nadine;
Baier, Sabrina;
Saier, Christina;
Groß, Maximilian;
Wätjen, Wim

Publication type:

Article

Caffeic Acid Phenethylester Increases Stress Resistance and Enhances Lifespan in <i>Caenorhabditis elegans</i> by Modulation of the Insulin-Like DAF-16 Signalling Pathway.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100256

By:

Havermann, Susannah;
Chovolou, Yvonni;
Humpf, Hans-Ulrich;
Wätjen, Wim

Publication type:

Article

Antioxidant Enzymes and Apoptosis.

Published in:

Drug Metabolism Reviews, 2004, v. 36, n. 3/4, p. 747, doi. 10.1081/DMR-200033488

By:

Kahl, Regine;
Kampkötter, Andreas;
Wätjen, Wim;
Chovolou, Yvonni

Publication type:

Article

The forkhead transcription factor FOXO4 sensitizes cancer cells to doxorubicin-mediated cytotoxicity.

Published in:

Carcinogenesis, 2008, v. 29, n. 11, p. 2045, doi. 10.1093/carcin/bgn184

By:

Regine Lüpertz;
Yvonni Chovolou;
Klaus Unfried;
Andreas Kampkötter;
Wim Wätjen;
Regine Kahl

Publication type:

Article

The Lignan Pinoresinol Induces Nuclear Translocation of DAF-16 in Caenorhabditis elegans but has No Effect on Life Span.

Published in:

Phytotherapy Research, 2015, v. 29, n. 6, p. 894, doi. 10.1002/ptr.5330

By:

Koch, Karoline;
Büchter, Christian;
Havermann, Susannah;
Wätjen, Wim

Publication type:

Article

Increased Expression of Catalase in Human Hepatoma Cells by the Soy Isoflavone, Daidzein.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2008, v. 102, n. 5, p. 437, doi. 10.1111/j.1742-7843.2007.00173.x

By:

Kampkötter, Andreas;
Wiegand, Christian;
Timpel, Claudia;
Röhrdanz, Elke;
Chovolou, Yvonni;
Kahl, Regine;
Wätjen, Wim

Publication type:

Article

Effects of Methylated Derivatives of Luteolin Isolated from Cyperus alopecuroides in Rat H4IIE Hepatoma Cells.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2006, v. 98, n. 2, p. 168, doi. 10.1111/j.1742-7843.2006.pto_300.x

By:

Michels, Gudrun;
Mohamed, Gamal A.;
Weber, Nadine;
Chovolou, Yvonni;
Kampkötter, Andreas;
Wätjen, Wim;
Proksch, Peter

Publication type:

Article

TSG (2,3,5,4′-Tetrahydroxystilbene-2-O- β -D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans.

Published in:

Oxidative Medicine & Cellular Longevity, 2015, v. 2015, p. 1, doi. 10.1155/2015/124357

By:

Büchter, Christian;
Zhao, Liang;
Havermann, Susannah;
Honnen, Sebastian;
Fritz, Gerhard;
Proksch, Peter;
Wätjen, Wim

Publication type:

Article