OpenURL Connection Search

Select item for more details and to access through your institution.

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29688-5
By:
- de Vries, Laura E.;
- Jansen, Patrick A. M.;
- Barcelo, Catalina;
- Munro, Justin;
- Verhoef, Julie M. J.;
- Pasaje, Charisse Flerida A.;
- Rubiano, Kelly;
- Striepen, Josefine;
- Abla, Nada;
- Berning, Luuk;
- Bolscher, Judith M.;
- Demarta-Gatsi, Claudia;
- Henderson, Rob W. M.;
- Huijs, Tonnie;
- Koolen, Karin M. J.;
- Tumwebaze, Patrick K.;
- Yeo, Tomas;
- Aguiar, Anna C. C.;
- Angulo-Barturen, Iñigo;
- Churchyard, Alisje
Publication type:
Article
Pantothenate and CoA biosynthesis in Apicomplexa and their promise as antiparasitic drug targets.
Published in:
PLoS Pathogens, 2021, v. 17, n. 12, p. 1, doi. 10.1371/journal.ppat.1010124
By:
- de Vries, Laura E.;
- Lunghi, Matteo;
- Krishnan, Aarti;
- Kooij, Taco W. A.;
- Soldati-Favre, Dominique
Publication type:
Article
Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide‐based substrates and covalent inhibitors.
Published in:
FEBS Journal, 2019, v. 286, n. 20, p. 3998, doi. 10.1111/febs.14953
By:
- Vries, Laura E.;
- Sanchez, Mateo I.;
- Groborz, Katarzyna;
- Kuppens, Laurie;
- Poreba, Marcin;
- Lehmann, Christine;
- Nevins, Neysa;
- Withers‐Martinez, Chrislaine;
- Hirst, David J.;
- Yuan, Fang;
- Arastu‐Kapur, Shirin;
- Horn, Martin;
- Mares, Michael;
- Bogyo, Matthew;
- Drag, Marcin;
- Deu, Edgar
Publication type:
Article
Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite.
Published in:
PLoS Pathogens, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.ppat.1007031
By:
- Lehmann, Christine;
- Tan, Michele Ser Ying;
- de Vries, Laura E.;
- Russo, Ilaria;
- Sanchez, Mateo Isidrio;
- Goldberg, Daniel E.;
- Deu, Edgar
Publication type:
Article
Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening.
Published in:
PLoS ONE, 2019, v. 14, n. 12, p. 1, doi. 10.1371/journal.pone.0226270
By:
- Sanchez, Mateo I.;
- de Vries, Laura E.;
- Lehmann, Christine;
- Lee, Jeong T.;
- Ang, Kenny K.;
- Wilson, Christopher;
- Chen, Steven;
- Arkin, Michelle R.;
- Bogyo, Matthew;
- Deu, Edgar
Publication type:
Article
Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum.
Published in:
Science Translational Medicine, 2019, v. 11, n. 510, p. 1, doi. 10.1126/scitranslmed.aas9917
By:
- Schalkwijk, Joost;
- Allman, Erik L.;
- Jansen, Patrick A. M.;
- de Vries, Laura E.;
- Verhoef, Julie M. J.;
- Jackowski, Suzanne;
- Botman, Peter N. M.;
- Beuckens-Schortinghuis, Christien A.;
- Koolen, Karin M. J.;
- Bolscher, Judith M.;
- Vos, Martijn W.;
- Miller, Karen;
- Reeves, Stacy A.;
- Pett, Helmi;
- Trevitt, Graham;
- Wittlin, Sergio;
- Scheurer, Christian;
- Sax, Sibylle;
- Fischli, Christoph;
- Angulo-Barturen, Iñigo
Publication type:
Article

Found: 6

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.

Pantothenate and CoA biosynthesis in Apicomplexa and their promise as antiparasitic drug targets.

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide‐based substrates and covalent inhibitors.

Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite.

Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening.

Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum.