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Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies.
Published in:
Nature Medicine, 2000, v. 6, n. 6, p. 667, doi. 10.1038/76243
By:
- Trojan, Andreas;
- Schultze, Joachim L.;
- Witzens, Mathias;
- Vonderheide, Robert H.;
- Ladetto, Marco;
- Donovan, John W.;
- Gribben, John G.
Publication type:
Article
ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R--mediated apoptosis.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2626, doi. 10.1172/JCI74056
By:
- Condamine, Thomas;
- Kumar, Vinit;
- Ramachandran, Indu R.;
- Je-In Youn;
- Celis, Esteban;
- Finnberg, Niklas;
- El-Deiry, Wafik S.;
- Winograd, Rafael;
- Vonderheide, Robert H.;
- English, Nickolas R.;
- Knight, Stella C.;
- Yagita, Hideo;
- McCaffrey, Judith C.;
- Antonia, Scott;
- Hockstein, Neil;
- Witt, Robert;
- Masters, Gregory;
- Bauer, Thomas;
- Gabrilovich, Dmitry I.
Publication type:
Article
Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression.
Published in:
2013
By:
- Mueller, Christian;
- Chulay, Jeffrey D;
- Trapnell, Bruce C;
- Humphries, Margaret;
- Carey, Brenna;
- Sandhaus, Robert A;
- McElvaney, Noel G;
- Messina, Louis;
- Tang, Qiushi;
- Rouhani, Farshid N;
- Campbell-Thompson, Martha;
- Fu, Ann Dongtao;
- Yachnis, Anthony;
- Knop, David R;
- Ye, Guo-Jie;
- Brantly, Mark;
- Calcedo, Roberto;
- Somanathan, Suryanarayan;
- Richman, Lee P;
- Vonderheide, Robert H
Publication type:
journal article
Human Treg responses allow sustained recombinant adeno-associated virus--mediated transgene expression.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 12, p. 5310, doi. 10.1172/JCI70314
By:
- Mueller, Christian;
- Chulay, Jeffrey D.;
- Trapnell, Bruce C.;
- Humphries, Margaret;
- Carey, Brenna;
- Sandhaus, Robert A.;
- McElvaney, Noel G.;
- Messina, Louis;
- Qiushi Tang;
- Rouhani, Farshid N.;
- Campbell-Thompson, Martha;
- Ann Dongtao Fu;
- Yachnis, Anthony;
- Knop, David R.;
- Guo-jie Ye;
- Brantly, Mark;
- Calcedo, Roberto;
- Somanathan, Suryanarayan;
- Richman, Lee P.;
- Vonderheide, Robert H.
Publication type:
Article
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24562-2
By:
- Bear, Adham S.;
- Blanchard, Tatiana;
- Cesare, Joseph;
- Ford, Michael J.;
- Richman, Lee P.;
- Xu, Chong;
- Baroja, Miren L.;
- McCuaig, Sarah;
- Costeas, Christina;
- Gabunia, Khatuna;
- Scholler, John;
- Posey, Avery D.;
- O'Hara, Mark H.;
- Smole, Anze;
- Powell, Daniel J.;
- Garcia, Benjamin A.;
- Vonderheide, Robert H.;
- Linette, Gerald P.;
- Carreno, Beatriz M.
Publication type:
Article
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23832-3
By:
- Yang, Fan;
- He, Zhenqiang;
- Duan, Hao;
- Zhang, Duo;
- Li, Juehui;
- Yang, Huijuan;
- Dorsey, Jay F.;
- Zou, Wei;
- Ali Nabavizadeh, S.;
- Bagley, Stephen J.;
- Abdullah, Kalil;
- Brem, Steven;
- Zhang, Lin;
- Xu, Xiaowei;
- Byrne, Katelyn T.;
- Vonderheide, Robert H.;
- Gong, Yanqing;
- Fan, Yi
Publication type:
Article
CD47 blockade as another immune checkpoint therapy for cancer.
Published in:
Nature Medicine, 2015, v. 21, n. 10, p. 1122, doi. 10.1038/nm.3965
By:
- Vonderheide, Robert H
Publication type:
Article
Immunotherapy at Large: The road to personalized cancer vaccines.
Published in:
Nature Medicine, 2013, v. 19, n. 9, p. 1098, doi. 10.1038/nm.3317
By:
- Vonderheide, Robert H;
- Nathanson, Katherine L
Publication type:
Article
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.
Published in:
Nature Genetics, 2009, v. 41, n. 10, p. 1144, doi. 10.1038/ng.441
By:
- Ruzankina, Yaroslava;
- Schoppy, David W.;
- Asare, Amma;
- Clark, Carolyn E.;
- Vonderheide, Robert H.;
- Brown, Eric J.
Publication type:
Article
Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells.
Published in:
Annals of the New York Academy of Sciences, 2009, v. 1174, p. 99, doi. 10.1111/j.1749-6632.2009.04939.x
By:
- Rech, Andrew J.;
- Vonderheide, Robert H.
Publication type:
Article
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46048-7
By:
- Kim, Il-Kyu;
- Diamond, Mark S.;
- Yuan, Salina;
- Kemp, Samantha B.;
- Kahn, Benjamin M.;
- Li, Qinglan;
- Lin, Jeffrey H.;
- Li, Jinyang;
- Norgard, Robert J.;
- Thomas, Stacy K.;
- Merolle, Maria;
- Katsuda, Takeshi;
- Tobias, John W.;
- Baslan, Timour;
- Politi, Katerina;
- Vonderheide, Robert H.;
- Stanger, Ben Z.
Publication type:
Article
CD40-Activated B Cell Cancer Vaccine Improves Second Clinical Remission and Survival in Privately Owned Dogs with Non-Hodgkin's Lymphoma.
Published in:
PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0024167
By:
- Sorenmo, Karin U.;
- Krick, Erika;
- Coughlin, Christina M.;
- Overley, Beth;
- Gregor, Thomas P.;
- Vonderheide, Robert H.;
- Mason, Nicola J.
Publication type:
Article
Homeostasis of peripheral FoxP3+ CD4+ regulatory T cells in patients with early and late stage breast cancer.
Published in:
Cancer Immunology, Immunotherapy, 2010, v. 59, n. 4, p. 599, doi. 10.1007/s00262-009-0780-x
By:
- Rech, Andrew J.;
- Mick, Rosemarie;
- Kaplan, David E.;
- Kyong-Mi Chang;
- Domchek, Susan M.;
- Vonderheide, Robert H.
Publication type:
Article
Telomerase as a universal tumor-associated antigen for cancer immunotherapy.
Published in:
Oncogene, 2002, v. 21, n. 4, p. 674, doi. 10.1038/sj.onc.1205074
By:
- Vonderheide, Robert H
Publication type:
Article
Engineering T cells for cancer: our synthetic future.
Published in:
Immunological Reviews, 2014, v. 257, n. 1, p. 7, doi. 10.1111/imr.12143
By:
- Vonderheide, Robert H.;
- June, Carl H.
Publication type:
Article
Mammary carcinoma cell derived cyclooxygenase 2 suppresses tumor immune surveillance by enhancing intratumoral immune checkpoint activity.
Published in:
2013
By:
- Markosyan, Nune;
- Chen, Edward P;
- Evans, Rebecca A;
- Ndong, Victoire;
- Vonderheide, Robert H;
- Smyth, Emer M
Publication type:
journal article
The spleen as a diagnostic specimen.
Published in:
Cancer (0008543X), 2001, v. 91, n. 11, p. 2001, doi. 10.1002/1097-0142(20010601)91:11<2001::AID-CNCR1225>3.0.CO;2-3
By:
- Kraus, Madeleine D.;
- Fleming, Mark D.;
- Vonderheide, Robert H.
Publication type:
Article
An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences.
Published in:
BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09424-z
By:
- Gurun, Burcu;
- Horton, Wesley;
- Murugan, Dhaarini;
- Zhu, Biqing;
- Leyshock, Patrick;
- Kumar, Sushil;
- Byrne, Katelyn T.;
- Vonderheide, Robert H.;
- Margolin, Adam A.;
- Mori, Motomi;
- Spellman, Paul T.;
- Coussens, Lisa M.;
- Speed, Terence P.
Publication type:
Article
Tumor cell-intrinsic EPHA2 suppresses anti-tumor immunity by regulating PTGS2 (COX-2).
Published in:
2019
By:
- Markosyan, Nune;
- Jinyang Li;
- Sun, Yu H.;
- Richman, Lee P.;
- Lin, Jeffrey H.;
- Fangxue Yan;
- Quinones, Liz;
- Sela, Yogev;
- Taiji Yamazoe;
- Gordon, Naomi;
- Tobias, John W.;
- Byrne, Katelyn T.;
- Rech, Andrew J.;
- FitzGerald, Garret A.;
- Stanger, Ben Z.;
- Vonderheide, Robert H.;
- Li, Jinyang;
- Yan, Fangxue;
- Yamazoe, Taiji
Publication type:
journal article
Tumor-Derived Myeloid Cell Chemoattractants and T Cell Exclusion in Pancreatic Cancer.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.605619
By:
- Vonderheide, Robert H.;
- Bear, Adham S.
Publication type:
Article
Metastatic progression is associated with dynamic changes in the local microenvironment.
Published in:
Nature Communications, 2016, v. 7, n. 9, p. 12819, doi. 10.1038/ncomms12819
By:
- Aiello, Nicole M.;
- Bajor, David L.;
- Norgard, Robert J.;
- Sahmoud, Amine;
- Bhagwat, Neha;
- Pham, Minh N.;
- Cornish, Toby C.;
- Iacobuzio-Donahue, Christine A.;
- Vonderheide, Robert H.;
- Stanger, Ben Z.
Publication type:
Article
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards.
Published in:
Nature Communications, 2016, v. 7, n. 7, p. 12150, doi. 10.1038/ncomms12150
By:
- Bronte, Vincenzo;
- Brandau, Sven;
- Chen, Shu-Hsia;
- Colombo, Mario P.;
- Frey, Alan B.;
- Greten, Tim F.;
- Mandruzzato, Susanna;
- Murray, Peter J.;
- Ochoa, Augusto;
- Ostrand-Rosenberg, Suzanne;
- Rodriguez, Paulo C.;
- Sica, Antonio;
- Umansky, Viktor;
- Vonderheide, Robert H.;
- Gabrilovich, Dmitry I.
Publication type:
Article
A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours.
Published in:
2018
By:
- Maity, Amit;
- Mick, Rosemarie;
- Huang, Alexander C.;
- George, Sangeeth M.;
- Farwell, Michael D.;
- Lukens, John N.;
- Berman, Abigail T.;
- Mitchell, Tara C.;
- Bauml, Josh;
- Schuchter, Lynn M.;
- O’Hara, Mark;
- Lin, Lilie L.;
- Demichele, Angela;
- Christodouleas, John P.;
- Haas, Naomi B.;
- Patsch, Dana M.;
- Hahn, Stephen M.;
- Minn, Andy J.;
- Wherry, E. John;
- Vonderheide, Robert H.
Publication type:
journal article
CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients.
Published in:
Science Translational Medicine, 2012, v. 4, n. 134, p. 1, doi. 10.1126/scitranslmed.3003330
By:
- Rech, Andrew J.;
- Mick, Rosemarie;
- Martin, Sunil;
- Recio, Adri;
- Aqui, Nicole A.;
- Powell Jr., Daniel J.;
- Colligon, Theresa A.;
- Trosko, Jennifer A.;
- Leinbach, Leah I.;
- Pletcher, Charles H.;
- Tweed, Carol K.;
- DeMichele, Angela;
- Fox, Kevin R.;
- Domchek, Susan M.;
- Riley, James L.;
- Vonderheide, Robert H.
Publication type:
Article
Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment.
Published in:
American Journal of Hematology, 2016, v. 91, n. 5, p. 453, doi. 10.1002/ajh.24303
By:
- Hexner, Elizabeth O.;
- Luger, Selina M.;
- Reshef, Ran;
- Jeschke, Grace R.;
- Mangan, James K.;
- Frey, Noelle V.;
- Frank, Dale M.;
- Richman, Lee P.;
- Vonderheide, Robert H.;
- Aqui, Nicole A.;
- Rosenbach, Misha;
- Zhang, Yi;
- Chew, Anne;
- Loren, Alison W.;
- Stadtmauer, Edward A.;
- Levine, Bruce L.;
- June, Carl H.;
- Emerson, Stephen G.;
- Porter, David L.
Publication type:
Article
A Phase I Trial of Repeated Intrapleural Adenoviral-mediated Interferon-β Gene Transfer for Mesothelioma and Metastatic Pleural Effusions.
Published in:
Molecular Therapy, 2010, v. 18, n. 4, p. 852, doi. 10.1038/mt.2009.309
By:
- Sterman, Daniel H.;
- Recio, Adri;
- Haas, Andrew R.;
- Vachani, Anil;
- Katz, Sharyn I.;
- Gillespie, Colin T.;
- Guanjun Cheng;
- Jing Sun;
- Moon, Edmund;
- Pereira, Luana;
- Xinzhong Wang;
- Heitjan, Daniel F.;
- Litzky, Leslie;
- June, Carl H.;
- Vonderheide, Robert H.;
- Carroll, Richard G.;
- Albelda, Steven M.
Publication type:
Article
1108. High Rate of Anti-Tumor Immune Responses in a Phase 1 Clinical Trial of Adenoviral-Interferon-Beta Gene Transfer for Malignant Mesothelioma (MM) and Malignant Pleural Effusions (MPE).
Published in:
Molecular Therapy, 2006, v. 13, p. S426, doi. 10.1016/j.ymthe.2006.08.1213
By:
- M. Albelda, Steven;
- Haas, Andrew;
- Gillespie, Collin;
- Recio, Andriana;
- Sun, Jing;
- Kapoor, Veena;
- Brown, Jennifer;
- Michael, Parr;
- Ho, Mitchell;
- Pastan, Ira;
- H. Vonderheide, Robert;
- Carroll, Richard;
- June, Carl;
- R. Kaiser, Larry;
- H. Sterman, Daniel
Publication type:
Article
Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma.
Published in:
British Journal of Haematology, 2003, v. 121, n. 6, p. 842, doi. 10.1046/j.1365-2141.2003.04375.x
By:
- Maecker, Britta;
- Anderson, Karen S.;
- von Bergwelt-Baildon, Michael S.;
- Weller, Edie;
- Vonderheide, Robert H.;
- Richardson, Paul G.;
- Schlossman, Robert L.;
- Menezes, Isaura A.;
- Xia, Zhinan;
- Munshi, Nikhil C.;
- Anderson, Kenneth C.;
- Nadler, Lee M.;
- Schultze, Joachim L.
Publication type:
Article
Reconsidering Dexamethasone for Antiemesis when Combining Chemotherapy and Immunotherapy.
Published in:
Oncologist, 2021, v. 26, n. 4, p. 269, doi. 10.1002/onco.13680
By:
- Janowitz, Tobias;
- Kleeman, Sam;
- Vonderheide, Robert H.
Publication type:
Article
A unique window of opportunity for practical reform of cancer clinical trials.
Published in:
Cancer (0008543X), 2021, v. 127, n. 16, p. 2855, doi. 10.1002/cncr.33585
By:
- Vogl, Dan T.;
- Sallée, Vicki;
- Hendricks, Maria C.;
- Redlinger Tabery, Colleen;
- Blair, Meghan L.;
- Dahlmeier, Erica;
- Meagher, Emma A.;
- Cohen, Roger B.;
- Vonderheide, Robert H.
Publication type:
Article
Lack of a significant pharmacokinetic interaction between maraviroc and tacrolimus in allogeneic HSCT recipients.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2015, v. 70, n. 7, p. 2078, doi. 10.1093/jac/dkv082
By:
- Ganetsky, Alex;
- Miano, Todd A.;
- Hughes, Mitchell E.;
- Vonderheide, Robert H.;
- Porter, David L.;
- Reshef, Ran
Publication type:
Article
Immigration of thoracic duct B lymphocytes into established germinal centers in the rat.
Published in:
European Journal of Immunology, 1990, v. 20, n. 1, p. 79, doi. 10.1002/eji.1830200112
By:
- Vonderheide, Robert H.;
- Hunt, Simon V.
Publication type:
Article

Found: 32

Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies.

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R--mediated apoptosis.

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression.

Human Treg responses allow sustained recombinant adeno-associated virus--mediated transgene expression.

Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.

Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.

CD47 blockade as another immune checkpoint therapy for cancer.

Immunotherapy at Large: The road to personalized cancer vaccines.

Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.

Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells.

Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma.

CD40-Activated B Cell Cancer Vaccine Improves Second Clinical Remission and Survival in Privately Owned Dogs with Non-Hodgkin's Lymphoma.

Homeostasis of peripheral FoxP3<sup>+</sup> CD4<sup>+</sup> regulatory T cells in patients with early and late stage breast cancer.

Telomerase as a universal tumor-associated antigen for cancer immunotherapy.

Engineering T cells for cancer: our synthetic future.

Mammary carcinoma cell derived cyclooxygenase 2 suppresses tumor immune surveillance by enhancing intratumoral immune checkpoint activity.

The spleen as a diagnostic specimen.

An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences.

Tumor cell-intrinsic EPHA2 suppresses anti-tumor immunity by regulating PTGS2 (COX-2).

Tumor-Derived Myeloid Cell Chemoattractants and T Cell Exclusion in Pancreatic Cancer.

Metastatic progression is associated with dynamic changes in the local microenvironment.

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards.

A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours.

CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients.

Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment.

A Phase I Trial of Repeated Intrapleural Adenoviral-mediated Interferon-β Gene Transfer for Mesothelioma and Metastatic Pleural Effusions.

1108. High Rate of Anti-Tumor Immune Responses in a Phase 1 Clinical Trial of Adenoviral-Interferon-Beta Gene Transfer for Malignant Mesothelioma (MM) and Malignant Pleural Effusions (MPE).

Viral antigen-specific CD8<sup>+</sup> T-cell responses are impaired in multiple myeloma.

Reconsidering Dexamethasone for Antiemesis when Combining Chemotherapy and Immunotherapy.

A unique window of opportunity for practical reform of cancer clinical trials.

Lack of a significant pharmacokinetic interaction between maraviroc and tacrolimus in allogeneic HSCT recipients.

Immigration of thoracic duct B lymphocytes into established germinal centers in the rat.