Works by Viswanath, Pavithra

Results: 24

Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-13C]-gluconolactone.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad092

By:

Batsios, Georgios;
Taglang, Celine;
Gillespie, Anne Marie;
Viswanath, Pavithra

Publication type:

Article

Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.

Published in:

Cancer & Metabolism, 2018, v. 6, p. 1, doi. 10.1186/s40170-018-0178-3

By:

Viswanath, Pavithra;
Radoul, Marina;
Izquierdo-Garcia, Jose Luis;
Luchman, Hema Artee;
Gregory Cairncross, J.;
Pieper, Russell O.;
Phillips, Joanna J.;
Ronen, Sabrina M.

Publication type:

Article

Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.

Published in:

Neuro-Oncology, 2022, v. 24, n. 11, p. 1898, doi. 10.1093/neuonc/noac112

By:

Minami, Noriaki;
Hong, Donghyun;
Stevers, Nicholas;
Barger, Carter J;
Radoul, Marina;
Hong, Chibo;
Chen, Lee;
Kim, Yaewon;
Batsios, Georgios;
Gillespie, Anne Marie;
Pieper, Russel O;
Costello, Joseph F;
Viswanath, Pavithra;
Ronen, Sabrina M

Publication type:

Article

Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.

Published in:

Neuro-Oncology, 2022, v. 24, n. 7, p. 1101, doi. 10.1093/neuonc/noac022

By:

Taglang, Céline;
Batsios, Georgios;
Mukherjee, Joydeep;
Tran, Meryssa;
Gillespie, Anne Marie;
Hong, Donghyun;
Ronen, Sabrina M;
Luchman, Hema Artee;
Pieper, Russell O;
Viswanath, Pavithra

Publication type:

Article

Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.

Published in:

Neuro-Oncology, 2021, v. 23, n. 9, p. 1509, doi. 10.1093/neuonc/noab093

By:

Viswanath, Pavithra;
Batsios, Georgios;
Ayyappan, Vinay;
Taglang, Céline;
Gillespie, Anne Marie;
Larson, Peder E Z;
Luchman, H Artee;
Costello, Joseph F;
Pieper, Russell O;
Ronen, Sabrina M

Publication type:

Article

CBMT-32. IMAGING A HALLMARK OF CANCER: TERT EXPRESSION LEADS TO MRS-DETECTABLE METABOLIC REPROGRAMMING.

Published in:

Neuro-Oncology, 2018, v. 20, p. vi39, doi. 10.1093/neuonc/noy148.151

By:

Viswanath, Pavithra;
Pieper, Russell;
Ronen, Sabrina

Publication type:

Article

EXTH-76. 1H AND HYPERPOLARIZED 13C MRS BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO TEMOZOLOMIDE THERAPY.

Published in:

Neuro-Oncology, 2018, v. 20, p. vi101, doi. 10.1093/neuonc/noy148.423

By:

Subramani, Elavarasan;
Najac, Chloe;
Batsios, Georgios;
Viswanath, Pavithra;
Radoul, Marina;
Gillespie, Anne Marie;
Pieper, Russell;
Ronen, Sabrina

Publication type:

Article

EXTH-35. IN VIVO 1H MRS DETECTS REDUCED 2HG PRODUCTION IN IDH1 MUTANT GLIOMAS TREATED WITH A DUAL PI3K/MTOR INHIBITOR.

Published in:

Neuro-Oncology, 2018, v. 20, p. vi92, doi. 10.1093/neuonc/noy148.384

By:

Batsios, Georgios;
Viswanath, Pavithra;
Gillespie, Anne Marie;
Subramani, Elavarasan;
Phillips, Joanna J;
Pieper, Russell;
Ronen, Sabrina

Publication type:

Article

HDAC inhibition in glioblastoma monitored by hyperpolarized 13C MRSI.

Published in:

NMR in Biomedicine, 2019, v. 32, n. 1, p. N.PAG, doi. 10.1002/nbm.4044

By:

Radoul, Marina;
Najac, Chloé;
Viswanath, Pavithra;
Mukherjee, Joydeep;
Kelly, Mark;
Gillespie, Anne Marie;
Chaumeil, Myriam M.;
Eriksson, Pia;
Delos Santos, Romelyn;
Pieper, Russell O.;
Ronen, Sabrina M.

Publication type:

Article

In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63160-y

By:

Batsios, Georgios;
Najac, Chloé;
Cao, Peng;
Viswanath, Pavithra;
Subramani, Elavarasan;
Saito, Yutaro;
Gillespie, Anne Marie;
Yoshihara, Hikari A. I.;
Larson, Peder;
Sando, Shinsuke;
Ronen, Sabrina M.

Publication type:

Article

PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47021-x

By:

Batsios, Georgios;
Viswanath, Pavithra;
Subramani, Elavarasan;
Najac, Chloe;
Gillespie, Anne Marie;
Santos, Romelyn Delos;
Molloy, Abigail R.;
Pieper, Russell O.;
Ronen, Sabrina M.

Publication type:

Article

Molecular imaging of Metabolic Reprograming in Mutant IDH Cells.

Published in:

Frontiers in Oncology, 2016, p. 1, doi. 10.3389/fonc.2016.00060

By:

Viswanath, Pavithra;
Chaumeil, Myriam M.;
Ronen, Sabrina M.

Publication type:

Article

In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39677-2

By:

Najac, Chloé;
Radoul, Marina;
Le Page, Lydia M.;
Batsios, Georgios;
Subramani, Elavarasan;
Viswanath, Pavithra;
Gillespie, Anne Marie;
Ronen, Sabrina M.

Publication type:

Article

Deuterium Metabolic Imaging—Rediscovery of a Spectroscopic Tool.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 9, p. 570, doi. 10.3390/metabo11090570

By:

Polvoy, Ilona;
Qin, Hecong;
Flavell, Robert R.;
Gordon, Jeremy;
Viswanath, Pavithra;
Sriram, Renuka;
Ohliger, Michael A.;
Wilson, David M.

Publication type:

Article

Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 2, p. 109, doi. 10.3390/metabo11020109

By:

Radoul, Marina;
Hong, Donghyun;
Gillespie, Anne Marie;
Najac, Chloé;
Viswanath, Pavithra;
Pieper, Russell O.;
Costello, Joseph F.;
Luchman, Hema Artee;
Ronen, Sabrina M.;
Martins, Andre F.

Publication type:

Article

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 6715, doi. 10.1038/ncomms7715

By:

Hameed P., Shahul;
Solapure, Suresh;
Patil, Vikas;
Henrich, Philipp P.;
Magistrado, Pamela A.;
Bharath, Sowmya;
Murugan, Kannan;
Viswanath, Pavithra;
Puttur, Jayashree;
Srivastava, Abhishek;
Bellale, Eknath;
Panduga, Vijender;
Shanbag, Gajanan;
Awasthy, Disha;
Landge, Sudhir;
Morayya, Sapna;
Koushik, Krishna;
Saralaya, Ramanatha;
Raichurkar, Anandkumar;
Rautela, Nikhil

Publication type:

Article

Acquisition and quantification pipeline for in vivo hyperpolarized 13C MR spectroscopy.

Published in:

Magnetic Resonance in Medicine, 2022, v. 87, n. 4, p. 1673, doi. 10.1002/mrm.29081

By:

Hong, Donghyun;
Batsios, Georgios;
Viswanath, Pavithra;
Gillespie, Anne Marie;
Vaidya, Manushka;
Larson, Peder E. Z.;
Ronen, Sabrina M.

Publication type:

Article

Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone.

Published in:

Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.589570

By:

Batsios, Georgios;
Taglang, Céline;
Cao, Peng;
Gillespie, Anne Marie;
Najac, Chloé;
Subramani, Elavarasan;
Wilson, David M.;
Flavell, Robert R.;
Larson, Peder E. Z.;
Ronen, Sabrina M.;
Viswanath, Pavithra

Publication type:

Article

Non-invasive assessment of telomere maintenance mechanisms in brain tumors.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20312-y

By:

Viswanath, Pavithra;
Batsios, Georgios;
Mukherjee, Joydeep;
Gillespie, Anne Marie;
Larson, Peder E. Z.;
Luchman, H. Artee;
Phillips, Joanna J.;
Costello, Joseph F.;
Pieper, Russell O.;
Ronen, Sabrina M.

Publication type:

Article

Metabolic Reprogramming in Mutant IDH1 Glioma Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118781

By:

Izquierdo-Garcia, Jose L.;
Viswanath, Pavithra;
Eriksson, Pia;
Chaumeil, Myriam M.;
Pieper, Russell O.;
Phillips, Joanna J.;
Ronen, Sabrina M.

Publication type:

Article

Development of a rapid and reliable assay for in vitro determination of compound cidality against the asexual stages of Plasmodium falciparum.

Published in:

Acta Parasitologica, 2016, v. 61, n. 4, p. 828, doi. 10.1515/ap-2016-0115

By:

Viswanath, Pavithra;
Morayya, Sapna;
Rautela, Nikhil;
Sinha, Achyut

Publication type:

Article

Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.252460

By:

Ning Zhao;
Yangjie Huang;
Yung-hua Wang;
Muir, Ryan K.;
Ying-Chu Chen;
Junnian Wei;
Hooshdaran, Nima;
Viswanath, Pavithra;
Youngho Seo;
Ruggero, Davide;
Renslo, Adam R.;
Evans, Michael J.

Publication type:

Article

Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32463-1

By:

Minami, Noriaki;
Hong, Donghyun;
Taglang, Celine;
Batsios, Georgios;
Gillespie, Anne Marie;
Viswanath, Pavithra;
Stevers, Nicholas;
Barger, Carter J.;
Costello, Joseph F.;
Ronen, Sabrina M.

Publication type:

Article

Repositioning: the fast track to new anti-malarial medicines?

Published in:

Malaria Journal, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2875-13-143

By:

Lotharius, Julie;
Gamo-Benito, Francisco Javier;
Angulo-Barturen, Iñigo;
Clark, Julie;
Connelly, Michele;
Ferrer-Bazaga, Santiago;
Parkinson, Tanya;
Viswanath, Pavithra;
Bandodkar, Balachandra;
Rautela, Nikhil;
Bharath, Sowmya;
Duffy, Sandra;
Avery, Vicky M.;
Möhrle, Jörg J.;
Guy, R. Kiplin;
Wells, Timothy

Publication type:

Article

Works by Viswanath, Pavithra

Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-<sup>13</sup>C]-gluconolactone.

Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.

Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.

Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.

Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.

CBMT-32. IMAGING A HALLMARK OF CANCER: TERT EXPRESSION LEADS TO MRS-DETECTABLE METABOLIC REPROGRAMMING.

EXTH-76. 1H AND HYPERPOLARIZED 13C MRS BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO TEMOZOLOMIDE THERAPY.

EXTH-35. IN VIVO 1H MRS DETECTS REDUCED 2HG PRODUCTION IN IDH1 MUTANT GLIOMAS TREATED WITH A DUAL PI3K/MTOR INHIBITOR.

HDAC inhibition in glioblastoma monitored by hyperpolarized <sup>13</sup>C MRSI.

In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine.

PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.

Molecular imaging of Metabolic Reprograming in Mutant IDH Cells.

In vivo investigation of hyperpolarized [1,3-<sup>13</sup>C<sub>2</sub>]acetoacetate as a metabolic probe in normal brain and in glioma.

Deuterium Metabolic Imaging—Rediscovery of a Spectroscopic Tool.

Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate.

Acquisition and quantification pipeline for in vivo hyperpolarized <sup>13</sup>C MR spectroscopy.

Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-<sup>13</sup>C]gluconolactone.

Non-invasive assessment of telomere maintenance mechanisms in brain tumors.

Metabolic Reprogramming in Mutant IDH1 Glioma Cells.

Development of a rapid and reliable assay for in vitro determination of compound cidality against the asexual stages of Plasmodium falciparum.

Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies.

Hyperpolarized δ-[1- <sup>13</sup>C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.

Repositioning: the fast track to new anti-malarial medicines?