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The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates.
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- Journal of Biomedical Science, 2019, v. 26, n. 1, p. N.PAG, doi. 10.1186/s12929-019-0579-9
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- Article
AMP-activated Protein Kinase Controls Immediate Early Genes Expression Following Synaptic Activation Through the PKA/CREB Pathway.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3716, doi. 10.3390/ijms19123716
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- Article
Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease.
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- Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00229
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- Article
Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease.
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- Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00229
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- Article
Growth arrest-specific 1 (Gas1) binds to and controls the maturation and processing of APP
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- 2011
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- Abstract
Generation and characterization of a CALHM1 knockout mouse model: Relevance for Alzheimer's disease
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- 2011
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- Abstract
Deregulation of AMPK activation in Alzheimer's disease and other tauopathies
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- 2011
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Resveratrol lowers beta-amyloid accumulation and deposition in vivo by controlling AMPK signaling
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- 2010
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Novel resveratrol analogues as activators of AMPK signaling and amyloid-beta peptide clearance
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- 2010
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P4-245: The Alzheimer's disease susceptibility gene CALHM1 encodes a brain calcium channel
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- 2008
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- Abstract
O4-06-06: The calcium homeostasis modulator CALHM1 controls Abeta levels and Alzheimer's disease risk
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- 2008
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- Abstract
AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo.
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- Scientific Reports, 2016, p. 26758, doi. 10.1038/srep26758
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- Article
CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice.
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- Scientific Reports, 2016, p. 24250, doi. 10.1038/srep24250
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- Article
Effect of the CALHM1 G330D and R154H Human Variants on the Control of Cytosolic Ca<sup>2+</sup> and Aβ Levels.
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- PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112484
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- Article
Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing.
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- Frontiers in Cellular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fncel.2018.00435
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- Article
Therapeutic potential of resveratrol in Alzheimer's disease.
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- BMC Neuroscience, 2008, v. 9, p. 1, doi. 10.1186/1471-2202-9-S2-S6
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- Article
Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-ß peptide degradation.
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- FASEB Journal, 2011, v. 25, n. 1, p. 219, doi. 10.1096/fj.10-167361
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- Article
Identification of potent small-molecule inhibitors of STAT3 with anti-inflammatory properties in RAW 264.7 macrophages.
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- FEBS Journal, 2012, v. 279, n. 20, p. 3791, doi. 10.1111/j.1742-4658.2012.08739.x
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- Article
Resveratrol mitigates lipopolysaccharide- and Aβ-mediated microglial inflammation by inhibiting the TLR4/NF-κB/STAT signaling cascade.
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- Journal of Neurochemistry, 2012, v. 120, n. 3, p. 461, doi. 10.1111/j.1471-4159.2011.07594.x
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- Article
Identification and biology of α-secretase.
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- Journal of Neurochemistry, 2012, v. 120, p. 34, doi. 10.1111/j.1471-4159.2011.07477.x
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- Article
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-β precursor protein.
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- Human Molecular Genetics, 2011, v. 20, n. 10, p. 2026, doi. 10.1093/hmg/ddr085
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- Article
Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process.
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- Cell Death & Disease, 2019, v. 10, n. 3, p. 1, doi. 10.1038/s41419-019-1464-x
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- Article
A Modification-Specific Peptide-Based immunization Approach Using CRM197 Carrier Protein: Development of a Selective Vaccine Against Pyroglutamate Aβ Peptides.
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- Molecular Medicine, 2016, v. 22, n. 1, p. 841, doi. 10.2119/molmed.2016.00218
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- Article
CB<sub>2</sub> Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer's Disease.
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- Molecular Medicine, 2014, v. 20, n. 1, p. 29, doi. 10.2119/molmed.2013.00140.revised
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- Article
CB<sub>2</sub> Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer's Disease.
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- Molecular Medicine, 2013, v. 19, n. 2, p. 357, doi. 10.2119/molmed.2013.00140
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- Article
CB<sub>2</sub> Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer's Disease.
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- Molecular Medicine, 2013, v. 19, n. 1, p. 357, doi. 10.2119/molmed.2013.00140
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- Article
Small-Molecule Activators of AMP-Activated Protein Kinase (AMPK), RSVA314 and RSVA405, Inhibit Adipogenesis.
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- Molecular Medicine, 2011, v. 17, n. 9/10, p. 1022, doi. 10.2119/molmed.2011.00163
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- Article
CALHM1 P86L Polymorphism Modulates CSF Aβ Levels in Cognitively Healthy Individuals at Risk for Alzheimer's Disease.
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- Molecular Medicine, 2011, v. 17, n. 9/10, p. 974, doi. 10.2119/molmed.2011.00154
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- Article
AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies.
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- Acta Neuropathologica, 2011, v. 121, n. 3, p. 337, doi. 10.1007/s00401-010-0759-x
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- Article
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes.
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- Nature, 2013, v. 495, n. 7440, p. 223, doi. 10.1038/nature11906
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- Article
Calcium signaling in neurodegeneration.
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- Molecular Neurodegeneration, 2009, v. 4, p. 1, doi. 10.1186/1750-1326-4-20
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- Article
Inhibition of AMP-Activated Protein Kinase Signaling Alleviates Impairments in Hippocampal Synaptic Plasticity Induced by Amyloid β.
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- Journal of Neuroscience, 2014, v. 34, n. 36, p. 12230, doi. 10.1523/JNEUROSCI.1694-14.2014
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- Article
Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke.
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- Proteome Science, 2014, v. 12, n. 1, p. 1, doi. 10.1186/1477-5956-12-24
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- Article