Works matching AU Villunger, Andreas

Results: 71

Efficient T cell receptor-mediated apoptosis in nonobese diabetic mouse thymocytes.

Published in:

Nature Immunology, 2003, v. 4, n. 8, p. 717, doi. 10.1038/ni0803-717

By:

Villunger, Andreas;
Marsden, Vanessa S.;
Strasser, Andreas

Publication type:

Article

Embryonic stem cell differentiation requires full length Chd1.

Published in:

Scientific Reports, 2015, p. 8007, doi. 10.1038/srep08007

By:

Piatti, Paolo;
Lim, Chin Yan;
Nat, Roxana;
Villunger, Andreas;
Geley, Stephan;
Shue, Yan Ting;
Soratroi, Claudia;
Moser, Markus;
Lusser, Alexandra

Publication type:

Article

Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53222-4

By:

Schapfl, Marina A.;
LoMastro, Gina M.;
Braun, Vincent Z.;
Hirai, Maretoshi;
Levine, Michelle S.;
Kiermaier, Eva;
Labi, Verena;
Holland, Andrew J.;
Villunger, Andreas

Publication type:

Article

The SKP2-p27 axis de?nes susceptibility to cell death upon CHK1 inhibition.

Published in:

Molecular Oncology, 2022, v. 16, n. 15, p. 2771, doi. 10.1002/1878-0261.13264

By:

Lohmüller, Michael;
Roeck, Bernhard F.;
Szabo, Tamas G.;
Schapfl, Marina A.;
Pegka, Fragka;
Herzog, Sebastian;
Villunger, Andreas;
Schuler, Fabian

Publication type:

Article

Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-?, e and ?

Published in:

EMBO Journal, 1998, v. 17, n. 14, p. 4046, doi. 10.1093/emboj/17.14.4046

By:

Kampfer, Sonja;
Hellbert, Karina;
Villunger, Andreas;
Doppler, Wolfgang;
Baier, Gottfried;
Grunike, Hans H.;
Überall, Florian

Publication type:

Article

The miR-26 family regulates early B cell development and transformation.

Published in:

Life Science Alliance, 2022, v. 5, n. 8, p. 1, doi. 10.26508/lsa.202101303

By:

Hutter, Katharina;
Lindner, Silke E.;
Kurschat, Constanze;
Rülicke, Thomas;
Villunger, Andreas;
Herzog, Sebastian

Publication type:

Article

T Cell Energy Metabolism Is a Target of Glucocorticoids in Mice, Healthy Humans, and MS Patients.

Published in:

Cells (2073-4409), 2023, v. 12, n. 3, p. 450, doi. 10.3390/cells12030450

By:

Meyer-Heemsoth, Leonie;
Mitschke, Katja;
Bier, Jasmina;
Schütz, Konstantin;
Villunger, Andreas;
Legler, Tobias J.;
Weber, Martin S.;
Lühder, Fred;
Reichardt, Holger M.

Publication type:

Article

Cell-Specific Immune Regulation by Glucocorticoids in Murine Models of Infection and Inflammation.

Published in:

Cells (2073-4409), 2022, v. 11, n. 14, p. N.PAG, doi. 10.3390/cells11142126

By:

Rocamora-Reverte, Lourdes;
Villunger, Andreas;
Wiegers, G. Jan

Publication type:

Article

BH3-Only Proapoptotic Bcl-2 Family Members Noxa and Puma Mediate Neural Precursor Cell Death.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 27, p. 7257, doi. 10.1523/JNEUROSCI.0196-06.2006

By:

Akhtar, Rizwan S.;
Ying Geng;
Klocke, Barbara J.;
Latham, Cecelia B.;
Villunger, Andreas;
Michalak, Ewa M.;
Strasser, Andreas;
Carroll, Steven L.;
Roth, Kevin A.

Publication type:

Article

The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.

Published in:

2017

By:

Ebner, Florian;
Sedlyarov, Vitaly;
Tasciyan, Saren;
Ivin, Masa;
Kratochvill, Franz;
Gratz, Nina;
Kenner, Lukas;
Villunger, Andreas;
Sixt, Michael;
Kovarik, Pavel

Publication type:

journal article

Lapatinib and doxorubicin enhance the Stat1-dependent antitumor immune response.

Published in:

European Journal of Immunology, 2013, v. 43, n. 10, p. 2718, doi. 10.1002/eji.201242505

By:

Hannesdóttir, Lára;
Tymoszuk, Piotr;
Parajuli, Nirmala;
Wasmer, Marie‐Helene;
Philipp, Sonja;
Daschil, Nina;
Datta, Sebak;
Koller, Johann‐Benedikt;
Tripp, Christoph H.;
Stoitzner, Patrizia;
Müller‐Holzner, Elisabeth;
Wiegers, Gerrit Jan;
Sexl, Veronika;
Villunger, Andreas;
Doppler, Wolfgang

Publication type:

Article

The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0172850

By:

Voráčová, Kateřina;
Hájek, Jan;
Mareš, Jan;
Urajová, Petra;
Kuzma, Marek;
Cheel, José;
Villunger, Andreas;
Kapuscik, Alexandra;
Bally, Marcel;
Novák, Petr;
Kabeláč, Martin;
Krumschnabel, Gerhard;
Lukeš, Martin;
Voloshko, Ludmila;
Kopecký, Jiří;
Hrouzek, Pavel

Publication type:

Article

At a Crossroads to Cancer: How p53-Induced Cell Fate Decisions Secure Genome Integrity.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10883, doi. 10.3390/ijms221910883

By:

Rizzotto, Dario;
Englmaier, Lukas;
Villunger, Andreas

Publication type:

Article

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD.

Published in:

Biochemical Journal, 2012, v. 444, n. 3, p. 591, doi. 10.1042/BJ20111588

By:

RIBE, Elena M.;
JEAN, Ying Y.;
GOLDSTEIN, Rebecca L.;
MANZL, Claudia;
STEFANIS, Leonidas;
VILLUNGER, Andreas;
TROY, Carol M.

Publication type:

Article

Caspase-2 activation in the absence of PIDDosome formation.

Published in:

Journal of Cell Biology, 2009, v. 185, n. 2, p. 291, doi. 10.1083/jcb.200811105

By:

Manzl, Claudia;
Krumschnabel, Gerhard;
Bock, Florian;
Sohm, Benedicte;
Labi, Verena;
Baumgartner, Florian;
Logette, Emmanuelle;
Tschopp, Jürg;
Villunger, Andreas

Publication type:

Article

Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.

Published in:

Journal of Cell Biology, 2007, v. 176, n. 4, p. 415, doi. 10.1083/jcb.200608070

By:

Naik, Edwina;
Michalak, Ewa M.;
Villunger, Andreas;
Adams, Jerry M.;
Strasser, Andreas

Publication type:

Article

p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis.

Published in:

Journal of Cell Biology, 2006, v. 175, n. 6, p. 861, doi. 10.1083/jcb.200607025

By:

Teis, David;
Taub, Nicole;
Kurzbauer, Robert;
Hilber, Diana;
de Araujo, Mariana E.;
Erlacher, Miriam;
Offterdinger, Martin;
Villunger, Andreas;
Geley, Stephan;
Bohn, Georg;
Klein, Christoph;
Hess, Michael W.;
Huber, Lukas A.

Publication type:

Article

Constituents of autocrine IL-6 loops in myeloma cell lines and their targeting for suppression of neoplastic growth by antibody strategies.

Published in:

International Journal of Cancer, 1996, v. 65, n. 4, p. 498, doi. 10.1002/(SICI)1097-0215(19960208)65:4<498::AID-IJC18>3.0.CO;2-6

By:

Villunger, Andreas;
Egle, Alexander;
Kos, Marion;
Hittmair, Anton;
Maly, Karl;
Greil, Richard

Publication type:

Article

Cellular polyploidy in organ homeostasis and regeneration.

Published in:

Protein & Cell, 2023, v. 14, n. 8, p. 560, doi. 10.1093/procel/pwac064

By:

Fang, Juntao;
de Bruin, Alain;
Villunger, Andreas;
Schiffelers, Raymond;
Lei, Zhiyong;
Sluijter, Joost P G

Publication type:

Article

Expression of Apo-1/Fas (CD95), Bcl-2, Bax and Bcl-x in myeloma cell lines: relationship between responsiveness to anti-Fas mab and p53 functional status.

Published in:

British Journal of Haematology, 1997, v. 97, n. 2, p. 418, doi. 10.1046/j.1365-2141.1997.382680.x

By:

Egle, Alexander;
Villunger, Andreas;
Marschitz, Ingrid;
Kos, Marion;
Hittmair, Anton;
Lukas, Peter;
Grünewald, Kurt;
Greil, Richard

Publication type:

Article

Extra centrosomes induce PIDD1‐mediated inflammation and immunosurveillance.

Published in:

EMBO Journal, 2023, v. 42, n. 20, p. 1, doi. 10.15252/embj.2023113510

By:

Garcia‐Carpio, Irmina;
Braun, Vincent Z;
Weiler, Elias S;
Leone, Marina;
Niñerola, Sergio;
Barco, Angel;
Fava, Luca L;
Villunger, Andreas

Publication type:

Article

BCL‐2‐family protein tBID can act as a BAX‐like effector of apoptosis.

Published in:

EMBO Journal, 2022, v. 41, n. 2, p. 1, doi. 10.15252/embj.2021108690

By:

Flores‐Romero, Hector;
Hohorst, Lisa;
John, Malina;
Albert, Marie‐Christine;
King, Louise E;
Beckmann, Laura;
Szabo, Tamas;
Hertlein, Vanessa;
Luo, Xu;
Villunger, Andreas;
Frenzel, Lukas P;
Kashkar, Hamid;
Garcia‐Saez, Ana J

Publication type:

Article

Centriolar distal appendages activate the centrosome‐PIDDosome‐p53 signalling axis via ANKRD26.

Published in:

EMBO Journal, 2021, v. 40, n. 4, p. 1, doi. 10.15252/embj.2020104844

By:

Burigotto, Matteo;
Mattivi, Alessia;
Migliorati, Daniele;
Magnani, Giovanni;
Valentini, Chiara;
Roccuzzo, Michela;
Offterdinger, Martin;
Pizzato, Massimo;
Schmidt, Alexander;
Villunger, Andreas;
Maffini, Stefano;
Fava, Luca L

Publication type:

Article

BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.

Published in:

EMBO Journal, 2014, v. 33, n. 19, p. 2171, doi. 10.15252/embj.201387244

By:

Andree, Maria;
Seeger, Jens M;
Schüll, Stephan;
Coutelle, Oliver;
Wagner‐Stippich, Diana;
Wiegmann, Katja;
Wunderlich, Claudia M;
Brinkmann, Kerstin;
Broxtermann, Pia;
Witt, Axel;
Fritsch, Melanie;
Martinelli, Paola;
Bielig, Harald;
Lamkemeyer, Tobias;
Rugarli, Elena I;
Kaufmann, Thomas;
Sterner‐Kock, Anja;
Wunderlich, F Thomas;
Villunger, Andreas;
Martins, L Miguel

Publication type:

Article

Stop competing, start talking!

Published in:

EMBO Journal, 2014, v. 33, n. 17, p. 1849, doi. 10.15252/embj.201489466

By:

Fava, Luca L;
Villunger, Andreas

Publication type:

Article

Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3-only proteins Bim and Bmf.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 1, p. 122, doi. 10.1002/emmm.201201235

By:

Labi, Verena;
Bertele, Daniela;
Woess, Claudia;
Tischner, Denise;
Bock, Florian J.;
Schwemmers, Sven;
Pahl, Heike L.;
Geley, Stephan;
Kunze, Mirjam;
Niemeyer, Charlotte M.;
Villunger, Andreas;
Erlacher, Miriam

Publication type:

Article

PUMA-mediated tumor suppression.

Published in:

Cell Cycle, 2010, v. 9, n. 21, p. 4269, doi. 10.4161/cc.9.21.13666

By:

Labi, Verena;
Villunger, Andreas

Publication type:

Article

Apoptosis in Activated T Cells.

Published in:

Cell Cycle, 2006, v. 5, n. 21, p. 2421, doi. 10.4161/cc.5.21.3397

By:

Häcker, Georg;
Bauer, Anette;
Villunger, Andreas

Publication type:

Article

The great escape: Is immune evasion required for tumor progression?

Published in:

Nature Medicine, 1999, v. 5, n. 8, p. 874, doi. 10.1038/11311

By:

Villunger, Andreas;
Strasser, Andreas

Publication type:

Article

Induction of Noxa-Mediated Apoptosis by Modified Vaccinia Virus Ankara Depends on Viral Recognition by Cytosolic Helicases, Leading to IRF-3/IFN-β-Dependent Induction of Pro-Apoptotic Noxa.

Published in:

PLoS Pathogens, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.ppat.1002083

By:

Ferrer, Pedro Eitz;
Potthoff, Stephanie;
Kirschnek, Susanne;
Gasteiger, Georg;
Kastenmüller, Wolfgang;
Ludwig, Holger;
Paschen, Stefan A.;
Villunger, Andreas;
Sutter, Gerd;
Drexler, Ingo;
Häcker, Georg

Publication type:

Article

Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling.

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 11, p. 1673, doi. 10.1128/MCB.00999-15

By:

Sakamoto, Kazuhito;
Wehde, Barbara L.;
Kyung Hyun Yoo;
Taemook Kim;
Rajbhandari, Nirakar;
Ha Youn Shin;
Triplett, Aleata A.;
Rädler, Patrick D.;
Schuler, Fabian;
Villunger, Andreas;
Keunsoo Kang;
Hennighausen, Lothar;
Wagner, Kay-Uwe

Publication type:

Article

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8<sup>+</sup> T cells sensitizing them to apoptotic cell death.

Published in:

Aging Cell, 2012, v. 11, n. 4, p. 579, doi. 10.1111/j.1474-9726.2012.00819.x

By:

Brunner, Stefan;
Herndler-Brandstetter, Dietmar;
Arnold, Christoph R.;
Wiegers, Gerrit Jan;
Villunger, Andreas;
Hackl, Matthias;
Grillari, Johannes;
Moreno-Villanueva, María;
Bürkle, Alexander;
Grubeck-Loebenstein, Beatrix

Publication type:

Article

PIDDosome-independent tumor suppression by Caspase-2.

Published in:

Cell Death & Differentiation, 2012, v. 19, n. 10, p. 1722, doi. 10.1038/cdd.2012.54

By:

Manzl, C;
Peintner, L;
Krumschnabel, G;
Bock, F;
Labi, V;
Drach, M;
Newbold, A;
Johnstone, R;
Villunger, Andreas

Publication type:

Article

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7.

Published in:

International Immunology, 2009, v. 21, n. 6, p. 715

By:

Nicholas D. Huntington;
Verena Labi;
Ana Cumano;
Paulo Vieira;
Andreas Strasser;
Andreas Villunger;
James P. Di Santo;
Nuno L. Alves

Publication type:

Article

Infiltrating CD11b.

Published in:

International Journal of Cancer, 2010, v. 126, n. 4, p. 896, doi. 10.1002/ijc.24805

By:

Parajuli, Nirmala;
Müller-Holzner, Elisabeth;
Böck, Günther;
Werner, Ernst R.;
Villunger, Andreas;
Doppler, Wolfgang

Publication type:

Article

Signalling strength determines proapoptotic functions of STING.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00573-w

By:

Gulen, Muhammet F.;
Koch, Ute;
Haag, Simone M.;
Schuler, Fabian;
Apetoh, Lionel;
Villunger, Andreas;
Radtke, Freddy;
Ablasser, Andrea

Publication type:

Article

Expression of the vault RNA protects cells from undergoing apoptosis.

Published in:

Nature Communications, 2015, v. 6, n. 5, p. 7030, doi. 10.1038/ncomms8030

By:

Amort, Melanie;
Nachbauer, Birgit;
Tuzlak, Selma;
Kieser, Arnd;
Schepers, Aloys;
Villunger, Andreas;
Polacek, Norbert

Publication type:

Article

The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest.

Published in:

Nature Communications, 2015, v. 6, n. 4, p. 6891, doi. 10.1038/ncomms7891

By:

Haschka, Manuel D.;
Soratroi, Claudia;
Kirschnek, Susanne;
Häcker, Georg;
Hilbe, Richard;
Geley, Stephan;
Villunger, Andreas;
Fava, Luca L.

Publication type:

Article

BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis.

Published in:

Apoptosis, 2013, v. 18, n. 11, p. 1306, doi. 10.1007/s10495-013-0890-y

By:

Wensveen, Felix;
Geest, Christian;
Libregts, Sten;
Derks, Ingrid;
Ekert, Paul;
Labi, Verena;
Villunger, Andreas;
Nolte, Martijn;
Eldering, Eric

Publication type:

Article

AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts.

Published in:

Apoptosis, 2013, v. 18, n. 8, p. 1008, doi. 10.1007/s10495-013-0850-6

By:

González-Gironès, Diana;
Moncunill-Massaguer, Cristina;
Iglesias-Serret, Daniel;
Cosialls, Ana;
Pérez-Perarnau, Alba;
Palmeri, Claudia;
Rubio-Patiño, Camila;
Villunger, Andreas;
Pons, Gabriel;
Gil, Joan

Publication type:

Article

Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members.

Published in:

Apoptosis, 2012, v. 17, n. 11, p. 1197, doi. 10.1007/s10495-012-0756-8

By:

Tischner, Denise;
Manzl, Claudia;
Soratroi, Claudia;
Villunger, Andreas;
Krumschnabel, Gerhard

Publication type:

Article

Bcl2 family proteins in carcinogenesis and the treatment of cancer.

Published in:

Apoptosis, 2009, v. 14, n. 4, p. 584, doi. 10.1007/s10495-008-0300-z

By:

Frenzel, Anna;
Grespi, Francesca;
Chmelewskij, Waldemar;
Villunger, Andreas

Publication type:

Article

Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses.

Published in:

Acta Neuropathologica, 2014, v. 127, n. 5, p. 713, doi. 10.1007/s00401-014-1248-4

By:

Schweingruber, Nils;
Fischer, Henrike;
Fischer, Lisa;
Brandt, Jens;
Karabinskaya, Anna;
Labi, Verena;
Villunger, Andreas;
Kretzschmar, Benedikt;
Huppke, Peter;
Simons, Mikael;
Tuckermann, Jan;
Flügel, Alexander;
Lühder, Fred;
Reichardt, Holger

Publication type:

Article

Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01850-4

By:

Schuler, Fabian;
Weiss, Johannes G.;
Lindner, Silke E.;
Lohmüller, Michael;
Herzog, Sebastian;
Labi, Verena;
Villunger, Andreas;
Spiegl, Simon F.;
Menke, Philipp;
Geley, Stephan

Publication type:

Article

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01022-4

By:

Ottina, Eleonora;
Peperzak, Victor;
Schoeler, Katia;
Carrington, Emma;
Sgonc, Roswitha;
Pellegrini, Marc;
Preston, Simon;
Herold, Marco J.;
Strasser, Andreas;
Villunger, Andreas

Publication type:

Article

Apoptosis as a Barrier against CIN and Aneuploidy.

Published in:

Cancers, 2023, v. 15, n. 1, p. 30, doi. 10.3390/cancers15010030

By:

Weiss, Johannes G.;
Gallob, Filip;
Rieder, Patricia;
Villunger, Andreas

Publication type:

Article

HPV‐induced host epigenetic reprogramming is lost upon progression to high‐grade cervical intraepithelial neoplasia.

Published in:

International Journal of Cancer, 2023, v. 152, n. 11, p. 2321, doi. 10.1002/ijc.34477

By:

Herzog, Chiara;
Vavourakis, Charlotte D.;
Barrett, James E.;
Karbon, Gerlinde;
Villunger, Andreas;
Wang, Jiangrong;
Sundström, Karin;
Dillner, Joakim;
Widschwendter, Martin

Publication type:

Article

Generation and Evaluation of an IPTG-Regulated Version of Vav-Gene Promoter for Mouse Transgenesis.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018051

By:

Grespi, Francesca;
Ottina, Eleonora;
Yannoutsos, Nikolaos;
Geley, Stephan;
Villunger, Andreas

Publication type:

Article

Mutually Exclusive Subsets of BH3-Only Proteins Are Activated by the p53 and c-Jun N-Terminal Kinase/c-Jun Signaling Pathways during Cortical Neuron Apoptosis Induced by Arsenite.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 19, p. 8732, doi. 10.1128/MCB.25.19.8732-8747.2005

By:

Hon Kit Wong;
Fricker, Michael;
Wyttenbach, Andreas;
Villunger, Andreas;
Michalak, Ewa M.;
Strasser, Andreas;
Tolkovsky, Aviva M.

Publication type:

Article

Amplified centrosomes—more than just a threat.

Published in:

EMBO Reports, 2024, v. 25, n. 10, p. 4153, doi. 10.1038/s44319-024-00260-0

By:

Kiermaier, Eva;
Stötzel, Isabel;
Schapfl, Marina A;
Villunger, Andreas

Publication type:

Article